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Cardiac Pathophysiology
Cardiac Pathophysiology

... • Chamber dilation and myocardial hypertrophy are compensatory mechanisms to increase the pumping capability of the heart. • Eventually, the heart fails from overwork ...
Coronary Artery Disease - Angina, Unstable Angina, Myocardial
Coronary Artery Disease - Angina, Unstable Angina, Myocardial

... individuals had received a diagnosis of vascular disease or had a high prevalence of coronary risk factors. While individuals who exercise rarely may be more likely to suffer a heart attack after strenuous exertion than those who exercise regularly, the absolute risk of a cardiac event after any sin ...
Congenital Heart Disease
Congenital Heart Disease

...  Pulmonary becomes low pressure system  Pressure decreases on right side of heart  Pressure increases on left side of heart  PDA closes due to oxygen constricting the ductus  Foramen ovale (opening between the atria) closes due to pressure changes in the heart Heart Pressures: Newborn ...
Unit 2: Exercise Physiology
Unit 2: Exercise Physiology

... Describe the anatomy of the heart with reference to the heart chambers, valves and major blood vessels ...
Chapter 12 Cardiovascular and Respiratory Health
Chapter 12 Cardiovascular and Respiratory Health

... release clotting factors to eventually form a scab. ...
Medical Management of Stable Coronary Artery Disease
Medical Management of Stable Coronary Artery Disease

... All patients with stable coronary artery disease require medical therapy to prevent disease progression and recurrent cardiovascular events. Three classes of medication are essential to therapy: lipid-lowering, antihypertensive, and antiplatelet agents. Lipid-lowering therapy is necessary to decreas ...
Title: Hypertension and Left Ventricular Hypertrophy (LVH) Author
Title: Hypertension and Left Ventricular Hypertrophy (LVH) Author

... LVH
represents
an
extreme
increase
in
the
left
ventricular
 mass
of
the
heart.
The
left
ventricle
is
the
part
of
the
heart
 most
responsible
for
pumping
blood
to
our
body,
and
like
 any
muscle,
grows
in
reaction
to
more
rigorous
use.
Most
 cases
of
LVH
are
thought
to
result
naturally
from
a
“hard‐ w ...
High-Sensitivity C-Reactive Protein and Cardiovascular
High-Sensitivity C-Reactive Protein and Cardiovascular

... a causative factor in atherothrombosis is lacking. Whether measurement of hsCRP levels provides consistent, clinically meaningful incremental predictive value in risk prediction and reclassification beyond conventional factors remains debated. Despite publication of guidelines on the use of hsCRP in ...
Advantages and Disadvantages of Beta- Adrenergic
Advantages and Disadvantages of Beta- Adrenergic

... fat content in the case of hyperlipidemia and patients at high risk, and the salt content) and to smoking habits, physical activity. stress. personality, and drug therapy, especially anovulant preparations. Other diseases, such as diabetes mellitus, which are associated with a high incidence of hype ...
Performance enhancing drug abuse and cardiovascular risk
Performance enhancing drug abuse and cardiovascular risk

... clinical perspective it is also worth noting that EPO is predominantly used to boost endurance exercise performance and in general has not crossed over to amateur and recreational sports performers. AS, HGH, HCG and insulin/insulin-like growth factors, however, are routinely used by professional, am ...
Anatomy of the Cardiovascular System
Anatomy of the Cardiovascular System

... – Causes: myocardial infarction – S/S: decreased pumping pressure in systemic circulation; retained fluids • Can lead to congestion in pulmonary circulation  pulmonary edema  right-sided heart failure ...
Heart Beat and Blood Pressure
Heart Beat and Blood Pressure

... The Cardiac Cycle • The heart beats or contracts 70 times per minute. The human heart will undergo over 3 billion contraction cycles during a normal lifetime. • The cardiac cycle consists of two parts: 1. systole (contraction of the heart muscle) The contraction of the ventricles that opens the v ...
Pathophysiology of Right Heart Failure
Pathophysiology of Right Heart Failure

... Ventricular Interdependence RA and RV distension reduce LV filling (reduced LV compliance) ↓SV and contribute to pulmonary oedema development effect is present in both systole and diastole ...
Cardiovasular-Heart-2404heart02-22-07
Cardiovasular-Heart-2404heart02-22-07

... • Multiple waves of impulses randomly signal the AV node • Signals ventricles to contract quickly and irregularly ...
11_Skarvan_The aging heart: what can echocardiography tells us
11_Skarvan_The aging heart: what can echocardiography tells us

... deposits in the mitral and aortic annulus. However, not more than a mild valvular regurgitation should be present. The diameter of the aortic root is usually increased and an atheromatosis of the ascending aorta of varying grade is usually found. Doppler measurements of transmitral and pulmonary ven ...
What is the mitral valve? What causes mitral valve disease? What
What is the mitral valve? What causes mitral valve disease? What

... from a breed with a high risk of developing mitral valve disease you might ask your vet to check them for a presence of a murmur. Most animals with mitral valve disease are middle-aged or older but young animals can be affected. The initial sign of mitral valve disease may be reluctance to exercise, ...
Lyme Carditis: Complete Atrioventricular Dissociation with Need for
Lyme Carditis: Complete Atrioventricular Dissociation with Need for

... brief asystoles; and iii) fluctuating bundle branch block depicting either transient His-Purkinje involvement ...
Is it Form or Function? - JACC: Cardiovascular Interventions
Is it Form or Function? - JACC: Cardiovascular Interventions

... which is perhaps more interesting, was that left ventricular ejection fraction and the anatomic burden of disease at baseline were predictors of the combined endpoints of death, myocardial infarction, or non–ST-segment elevation acute coronary syndromes, but the ischemic burden was not. These finding ...
6) Blood Flow and Blood Pressure
6) Blood Flow and Blood Pressure

... Stroke (CVA)= the brain is deprived of oxygen, there are 4 types. 1. thrombus: blood clot in the brain 2. Embolus: blood clot breaks loose & is carried by blood flow 3. Hemorrhage: great loss of blood 4. Aneurysm: weak spot in an arteryballoons up & may rupture ...
6) Blood Flow and Blood Pressure
6) Blood Flow and Blood Pressure

... Stroke (CVA)= the brain is deprived of oxygen, there are 4 types. 1. thrombus: blood clot in the brain 2. Embolus: blood clot breaks loose & is carried by blood flow 3. Hemorrhage: great loss of blood 4. Aneurysm: weak spot in an arteryballoons up & may rupture ...
Two Ecstasy-Induced Myocardial Infarctions During A Three Month
Two Ecstasy-Induced Myocardial Infarctions During A Three Month

... Compared with the previous case reports, our case presented with normal coronary arteries at first admission. It can be due to coronary artery vasospasm or resolved thrombosis. On the other hand, in his second admission, angiography showed total occlusion of the proximal part of the LAD — similar to ...
Cardiovascular disease in women
Cardiovascular disease in women

... Isolated systolic hypertension (with its higher incidence in older women) is at least as powerful a risk factor as hypertension (12) (Level IV). Additionally, hypertension is an important marker for patients with a highrisk profile (12). Reducing blood pressure with medication decreases cardiovascul ...
Update on Percutaneous Mitral Valve Therapy
Update on Percutaneous Mitral Valve Therapy

... regurgitation (MR ≥ 3+) due to primary abnormality of the mitral apparatus [degenerative MR] in patients who have been determined to be at prohibitive risk for mitral valve surgery by a heart team, which includes a cardiac surgeon experienced in mitral valve surgery and a cardiologist experienced in ...
Cardiovascular Pharmacology
Cardiovascular Pharmacology

... III. Background to Congestive Heart Failure Maintenance of Normal Heart Function Normal cardiac output needed to adequately perfuse peripheral organs ...
Food Animal Cardiology
Food Animal Cardiology

... high altitude disease, or high mountain disease Cor pulmonale reflects effect of lung dysfunction on heart, therefore, heart disease is secondary ...
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Cardiovascular disease



Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. Cardiovascular disease includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs are stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, atrial fibrillation, congenital heart disease, endocarditis, aortic aneurysms, peripheral artery disease and venous thrombosis.The underlying mechanisms vary depending on the disease in question. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow untreated strep throat.It is estimated that 90% of CVD is preventable. Prevention of atherosclerosis is by decreasing risk factors through: healthy eating, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating high blood pressure and diabetes is also beneficial. Treating people who have strep throat with antibiotics can decrease the risk of rheumatic heart disease. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. The United States Preventive Services Task Force recommends against its use for prevention in women less than 55 and men less than 45 years old; however, in those who are older it is recommends in some individuals. Treatment of those who have CVD improves outcomes.Cardiovascular diseases are the leading cause of death globally. This is true in all areas of the world except Africa. Together they resulted in 17.3 million deaths (31.5%) in 2013 up from 12.3 million (25.8%) in 1990. Deaths, at a given age, from CVD are more common and have been increasing in much of the developing world, while rates have declined in most of the developed world since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80 while it is around 68 in the developing world. Disease onset is typically seven to ten years earlier in men as compared to women.
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