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Chapter 23 - dewhozitz.net
Chapter 23 - dewhozitz.net

... -> q = square root of 1/10,000 = 0.01 -> p = freq. of dominant allele = 1 - q = 0.99 -> freq. of heterozygotes = 2pq = 2 (0.99)(0.01) = 0.0198 or ~2 % ⇒ This is the predicted presence of PKU carriers in US population ...
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Evolution: Natural Selection II
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The Selfish Gene

The Selfish Gene is a book on evolution by Richard Dawkins, published in 1976. It builds upon the principal theory of George C. Williams's first book Adaptation and Natural Selection. Dawkins used the term ""selfish gene"" as a way of expressing the gene-centred view of evolution as opposed to the views focused on the organism and the group, popularising ideas developed during the 1960s by W. D. Hamilton and others. From the gene-centred view follows that the more two individuals are genetically related, the more sense (at the level of the genes) it makes for them to behave selflessly with each other. This should not be confused with misuse of the term along the lines of a selfishness gene.An organism is expected to evolve to maximise its inclusive fitness—the number of copies of its genes passed on globally (rather than by a particular individual). As a result, populations will tend towards an evolutionarily stable strategy. The book also coins the term meme for a unit of human cultural evolution analogous to the gene, suggesting that such ""selfish"" replication may also model human culture, in a different sense. Memetics has become the subject of many studies since the publication of the book.In the foreword to the book's 30th-anniversary edition, Dawkins said he ""can readily see that [the book's title] might give an inadequate impression of its contents"" and in retrospect thinks he should have taken Tom Maschler's advice and called the book The Immortal Gene.
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