Detection of cystic fibrosis transmembrane conductance regulator
... analysis of the CFTR gene using varied screening methods, a number of cases remain unsolved and could be attributable to the presence of large gene rearrangements, as recently shown for CF patients. METHODS: We carried out a complete CFTR gene study in a group of 222 CBAVD patients with strict diagn ...
... analysis of the CFTR gene using varied screening methods, a number of cases remain unsolved and could be attributable to the presence of large gene rearrangements, as recently shown for CF patients. METHODS: We carried out a complete CFTR gene study in a group of 222 CBAVD patients with strict diagn ...
Selection and Adaptation of Fitness
... sexual maturity, return timing to the natal stream, resulting size at spawning) have been shown to be under selection (van den Berghe and Gross 1989; Seamons et al. 2004, 2007; Serbezov et al. 2010; Anderson et al. 2010). Such traits tend to evolve quickly under consistent directional selection (Cro ...
... sexual maturity, return timing to the natal stream, resulting size at spawning) have been shown to be under selection (van den Berghe and Gross 1989; Seamons et al. 2004, 2007; Serbezov et al. 2010; Anderson et al. 2010). Such traits tend to evolve quickly under consistent directional selection (Cro ...
CFTR Mutations in Congenital Absence of Vas Deferens
... mutation. In the CBAVD patients in which a mutation is found on both CFTR genes, about 88% of them carry one severe mutation on one CFTR gene and a mild mutation on the second CFTR gene, and about 12% carry mild mutations on both CFTR genes (7). This in contrast to CF, were about 88% of the CF patie ...
... mutation. In the CBAVD patients in which a mutation is found on both CFTR genes, about 88% of them carry one severe mutation on one CFTR gene and a mild mutation on the second CFTR gene, and about 12% carry mild mutations on both CFTR genes (7). This in contrast to CF, were about 88% of the CF patie ...
Visualization, description and analysis of the Drosophila melanogaster
... evolutionary process. On one hand, the molecule is intrinsically mutable, being this the origin of genetic variation. On the other hand, it allows the replication of old and new variants from one generation to another. The reproductive or survival advantage or disadvantage an individual has for carr ...
... evolutionary process. On one hand, the molecule is intrinsically mutable, being this the origin of genetic variation. On the other hand, it allows the replication of old and new variants from one generation to another. The reproductive or survival advantage or disadvantage an individual has for carr ...
Exam 2 Answer Key Spring 1996 Mcbio 316 - page 1
... As expected, ØPK2 would be repressed by a ØPK2 lysogen c. Suggest a simple explanation for the behavior of ØPK1 on each of these strains. Either the repressor produced by the ØPK2 lysogen can also repress any superinfecting ØPK1 (that is, the two phage are homoimmune) or the ØPK2 lysogen produces a ...
... As expected, ØPK2 would be repressed by a ØPK2 lysogen c. Suggest a simple explanation for the behavior of ØPK1 on each of these strains. Either the repressor produced by the ØPK2 lysogen can also repress any superinfecting ØPK1 (that is, the two phage are homoimmune) or the ØPK2 lysogen produces a ...
Convergent Evolution in the Genetic Basis of Müllerian Mimicry in
... colored wing patterns in local populations and different phenotypes between geographic regions of Central and South America, while H. numata is a species with polymorphic populations in which a single genetic locus controls multiple morphs. A positional cloning approach in H. melpomene led to identi ...
... colored wing patterns in local populations and different phenotypes between geographic regions of Central and South America, while H. numata is a species with polymorphic populations in which a single genetic locus controls multiple morphs. A positional cloning approach in H. melpomene led to identi ...
Convergent Evolution in the Genetic Basis of Müllerian
... colored wing patterns in local populations and different phenotypes between geographic regions of Central and South America, while H. numata is a species with polymorphic populations in which a single genetic locus controls multiple morphs. A positional cloning approach in H. melpomene led to identi ...
... colored wing patterns in local populations and different phenotypes between geographic regions of Central and South America, while H. numata is a species with polymorphic populations in which a single genetic locus controls multiple morphs. A positional cloning approach in H. melpomene led to identi ...
Mechanisms and impact of genetic recombination in the evolution of
... [7]. In addition to geography, additional factors including, age, smoking and co-infection with other diseases such as HIV predispose individuals to pneumococcal infections [8]. At least 93 pneumococcal serotypes are known, based on the structure and antigenicity of the pneumococcal polysaccharide c ...
... [7]. In addition to geography, additional factors including, age, smoking and co-infection with other diseases such as HIV predispose individuals to pneumococcal infections [8]. At least 93 pneumococcal serotypes are known, based on the structure and antigenicity of the pneumococcal polysaccharide c ...
Learning objectives
... 38. Describe the advantages and disadvantages of water as a respiratory medium. 39. Describe countercurrent exchange in fish gills. Explain why it is more efficient than the concurrent flow of water and blood. 40. Describe the advantages and disadvantages of air as a respiratory medium and explain h ...
... 38. Describe the advantages and disadvantages of water as a respiratory medium. 39. Describe countercurrent exchange in fish gills. Explain why it is more efficient than the concurrent flow of water and blood. 40. Describe the advantages and disadvantages of air as a respiratory medium and explain h ...
Methods for detection of point mutations
... for amplification. The error rate of Taq polymerase is in the range of 1024 to 1025 per nucleotide and is strongly affected by the reaction conditions (e.g., concentrations of magnesium chloride and dNTPs, pH, and temperature). Depending on the method of choice, polymerase errors may contribute reas ...
... for amplification. The error rate of Taq polymerase is in the range of 1024 to 1025 per nucleotide and is strongly affected by the reaction conditions (e.g., concentrations of magnesium chloride and dNTPs, pH, and temperature). Depending on the method of choice, polymerase errors may contribute reas ...
36 The Roots of Narcissus: Old and New Models of the Evolution of
... nonnarcissists. Although selfreports of a larger penis might be explained by the selfenhancing tendencies of narcissists, other findings are more difficult to explain as artifacts of reporting. Thus, some connection between physical characteris tics and narcissistic attributes m ...
... nonnarcissists. Although selfreports of a larger penis might be explained by the selfenhancing tendencies of narcissists, other findings are more difficult to explain as artifacts of reporting. Thus, some connection between physical characteris tics and narcissistic attributes m ...
A GENETIC LINKAGE MAP OF Phycomyces blakesleeanus
... fragments (contigs), with 99.4% being covered in 51 scaffolds. However, when I started ...
... fragments (contigs), with 99.4% being covered in 51 scaffolds. However, when I started ...
Sp. A Sp. B Sp. C Crown group Stem group
... angiosperms and their sister group among living gymnosperms; node "B" represents the most recent common ancestor of all modern (living) angiosperms. The stem lineage of angiosperms runs from B to A; the crown group of angiosperms includes all descendants of B. By the time that B arose (but possibly ...
... angiosperms and their sister group among living gymnosperms; node "B" represents the most recent common ancestor of all modern (living) angiosperms. The stem lineage of angiosperms runs from B to A; the crown group of angiosperms includes all descendants of B. By the time that B arose (but possibly ...
One - Svet logike
... our own species, and merely hints at the promise Darwin sees in his view of life, ethics and politics come to the foreground in The Descent of Man. Here Darwin puts forward an evolutionary explanation of our ability to sense the difference between right and wrong, he suggests ways in which his natur ...
... our own species, and merely hints at the promise Darwin sees in his view of life, ethics and politics come to the foreground in The Descent of Man. Here Darwin puts forward an evolutionary explanation of our ability to sense the difference between right and wrong, he suggests ways in which his natur ...
The struggle for existence. How the notion of carrying capacity, K
... understanding population regulation in the simplest organisms or cases, and many general conclusions from logistic models should be true also for more realistic situations. Furthermore, the Lotka-Volterra extension of the logistic to competition is also unrealistic for the same reasons as is the log ...
... understanding population regulation in the simplest organisms or cases, and many general conclusions from logistic models should be true also for more realistic situations. Furthermore, the Lotka-Volterra extension of the logistic to competition is also unrealistic for the same reasons as is the log ...
Reebop Ratios - West Branch Schools
... Mendel and Charles Darwin were alive, “blending inheritance” was a popular idea. • According to blending inheritance, traits from parents “blended” in offspring producing intermediate traits. • Example: The offspring of one short parent and one tall parent would be of medium height. This offspring w ...
... Mendel and Charles Darwin were alive, “blending inheritance” was a popular idea. • According to blending inheritance, traits from parents “blended” in offspring producing intermediate traits. • Example: The offspring of one short parent and one tall parent would be of medium height. This offspring w ...
Committee Opinion #691
... If an individual is found to be a carrier for a specific condition, the individual’s reproductive partner should be offered testing in order to receive informed genetic counseling about potential reproductive outcomes. Concurrent screening of the patient and her partner is suggested if there are tim ...
... If an individual is found to be a carrier for a specific condition, the individual’s reproductive partner should be offered testing in order to receive informed genetic counseling about potential reproductive outcomes. Concurrent screening of the patient and her partner is suggested if there are tim ...
Genetic diversity, virulence and fitness evolution in an obligate
... 2009). When cooperative interactions are considered, the evolutionary relationships between virulence and transmission then become even more complex (Alizon & Lion, 2011; Alizon et al., 2013). It is clear that more empirical studies of the effects on virulence and transmission in parasites evolving ...
... 2009). When cooperative interactions are considered, the evolutionary relationships between virulence and transmission then become even more complex (Alizon & Lion, 2011; Alizon et al., 2013). It is clear that more empirical studies of the effects on virulence and transmission in parasites evolving ...
MeCP2 mutations in children with and without
... protein or interfering with its association with transcriptional co-repressors.25,26 Most studies have reported a relatively high prevalence of de novo mutations in the MeCP2 gene in RTT.14,16-24 These findings are consistent with a high sporadic mutation rate and high incidence of isolated cases.8, ...
... protein or interfering with its association with transcriptional co-repressors.25,26 Most studies have reported a relatively high prevalence of de novo mutations in the MeCP2 gene in RTT.14,16-24 These findings are consistent with a high sporadic mutation rate and high incidence of isolated cases.8, ...
Pristionchus pacificus
... biology (Hong and Sommer, 2006). P. pacificus is a self-fertilizing hermaphrodite, has a 4-day life cycle at 20°C and can be cultured on OP50. P. pacificus is amenable to various cellular, genetic and molecular techniques successfully used in C. elegans. In addition to forward genetics, morpholino k ...
... biology (Hong and Sommer, 2006). P. pacificus is a self-fertilizing hermaphrodite, has a 4-day life cycle at 20°C and can be cultured on OP50. P. pacificus is amenable to various cellular, genetic and molecular techniques successfully used in C. elegans. In addition to forward genetics, morpholino k ...
CFTR mutation classifications toward genotype
... (CFTR) gene, also referred to as ABCC7, cause Cystic Fibrosis (CF), a severe autosomal recessive disease. CF affects 1 in 2,500 to 4,500 newborns among the Caucasian population. All other ethnic groups are affected to a lesser extent. In 1989, Francis Collins, Lap-Chee Tsui and John R. Riordan (Kere ...
... (CFTR) gene, also referred to as ABCC7, cause Cystic Fibrosis (CF), a severe autosomal recessive disease. CF affects 1 in 2,500 to 4,500 newborns among the Caucasian population. All other ethnic groups are affected to a lesser extent. In 1989, Francis Collins, Lap-Chee Tsui and John R. Riordan (Kere ...
Positive and Negative Selection on the Human Genome
... mutations that survive to be polymorphic in a population are either neutral or advantageous. Standing polymorphism, therefore, would not be of health concern. The increased rate of stillbirths and prereproductive mortality with inbreeding reveals substantial effects of partially recessive deleteriou ...
... mutations that survive to be polymorphic in a population are either neutral or advantageous. Standing polymorphism, therefore, would not be of health concern. The increased rate of stillbirths and prereproductive mortality with inbreeding reveals substantial effects of partially recessive deleteriou ...
Baldwinian Accounts of Language Evolution
... neglected evolutionary process of the Baldwin effect has been widely acknowledged. Especially in the field of language evolution, the Baldwin effect (Baldwin 1896d, Simpson 1953) has been expected to salvage the long-lasting deadlocked situation of modern linguistics: i.e., it may shed light on the ...
... neglected evolutionary process of the Baldwin effect has been widely acknowledged. Especially in the field of language evolution, the Baldwin effect (Baldwin 1896d, Simpson 1953) has been expected to salvage the long-lasting deadlocked situation of modern linguistics: i.e., it may shed light on the ...
pdf
... is unclear what circumstances caused this relatively rapid speciation and migrations of these taxa (The Yeti sample, we are told, comes from the mountains of Nepal, while the Leprechaun seems to exist primarily in Ireland). But Bogeyreta is the most taxon-rich monophyletic group encountered so far, ...
... is unclear what circumstances caused this relatively rapid speciation and migrations of these taxa (The Yeti sample, we are told, comes from the mountains of Nepal, while the Leprechaun seems to exist primarily in Ireland). But Bogeyreta is the most taxon-rich monophyletic group encountered so far, ...
Chapter 15 Powerpoint
... How to Use This Presentation • To View the presentation as a slideshow with effects select “View” on the menu bar and click on “Slide Show.” • To advance through the presentation, click the right-arrow key or the space bar. • From the resources slide, click on any resource to see a presentation for ...
... How to Use This Presentation • To View the presentation as a slideshow with effects select “View” on the menu bar and click on “Slide Show.” • To advance through the presentation, click the right-arrow key or the space bar. • From the resources slide, click on any resource to see a presentation for ...
Koinophilia
Koinophilia is an evolutionary hypothesis concerning sexual selection which proposes that animals seeking mate preferentially choose individuals with a minimum of unusual features. Koinophilia intends to explain the clustering of organisms into species and other issues described by Darwin's Dilemma. The term derives from the Greek, koinos, ""the usual"", and philos, ""fondness"".Natural selection causes beneficial inherited features to become more common and eventually replace their disadvantageous counterparts. A sexually-reproducing animal would be expected to avoid individuals with unusual features, and to prefer to mate with individuals displaying a predominance of common or average features. This means that mates displaying mutant features are also avoided. This is advantageous because most mutations that manifest themselves as changes in appearance, functionality or behavior, are disadvantageous. Because it is impossible to judge whether a new mutation is beneficial or not, koinophilic animals avoid them all, at the cost of avoiding the occasional beneficial mutation. Thus, koinophilia, although not infallible in its ability to distinguish fit from unfit mates, is a good strategy when choosing a mate. A koinophilic choice ensures that offspring are likely to inherit features that have been successful in the past.Koinophilia differs from assortative mating, where ""like prefers like"". If like preferred like, leucistic animals (such as white peacocks) would be sexually attracted to one another, and a leucistic subspecies would come into being. Koinophilia predicts that this is unlikely because leucistic animals are attracted to the average in the same way as other animals. Since non-leucistic animals are not attracted by leucism, few leucistic individuals find mates, and leucistic lineages will rarely form.Koinophilia provides simple explanations for the rarity of speciation (in particular Darwin's Dilemma), evolutionary stasis, punctuated equilibria, and the evolution of cooperation. Koinophilia might also contribute to the maintenance of sexual reproduction, preventing its reversion to the much simpler and inherently more advantageous asexual form of reproduction.The koinophilia hypothesis is supported by research into the physical attractiveness of human faces by Judith Langlois and her co-workers. They found that the average of two human faces was more attractive than either of the faces from which that average was derived. The more faces (of the same gender and age) that were used in the averaging process the more attractive and appealing the average face became. This work into averageness supports koinophilia as an explanation of what constitutes a beautiful face, and how the individuality of a face is recognized.