CELL WALLS OF GROWING PLANT CELLS
... significantly increased the hydration of cellulose composite; hydration rate was 15 -16% more than the composite without RG-II and thus increased the pellicle extensibility. From the results, it is evidenced that cell wall extension is not only the consequences of breaking hydrogen bonds between cel ...
... significantly increased the hydration of cellulose composite; hydration rate was 15 -16% more than the composite without RG-II and thus increased the pellicle extensibility. From the results, it is evidenced that cell wall extension is not only the consequences of breaking hydrogen bonds between cel ...
Selective and differential interactions of BNN27
... Nerve growth factor (NGF) holds a pivotal role in brain development and maintenance, been also involved in the pathophysiology of neurodegenerative diseases. Here, we provide evidence that a novel C17-spiroepoxy steroid derivative, BNN27, specifically interacts with and activates the TrkA receptor of ...
... Nerve growth factor (NGF) holds a pivotal role in brain development and maintenance, been also involved in the pathophysiology of neurodegenerative diseases. Here, we provide evidence that a novel C17-spiroepoxy steroid derivative, BNN27, specifically interacts with and activates the TrkA receptor of ...
Nanoscale Architecture of Endoplasmic Reticulum Export Sites and
... produced by plant cells are unstable, transient membrane structures that are resorbed back into the ER unless they are immediately transferred to a Golgi stack. Considering the slow rate of chemical fixation compared to the rate of COPII vesicle assembly/disassembly and the rapid translational movem ...
... produced by plant cells are unstable, transient membrane structures that are resorbed back into the ER unless they are immediately transferred to a Golgi stack. Considering the slow rate of chemical fixation compared to the rate of COPII vesicle assembly/disassembly and the rapid translational movem ...
The SOX9 upstream region prone to chromosomal aberrations
... existing in strategies available to prevent and treat these diseases. Post-transcriptional and post-translational mechanisms undoubtedly participate in modulating SOX9 protein level and activity, but above that, it is clear that transcription is a first and critical level of regulation of SOX9 (6). ...
... existing in strategies available to prevent and treat these diseases. Post-transcriptional and post-translational mechanisms undoubtedly participate in modulating SOX9 protein level and activity, but above that, it is clear that transcription is a first and critical level of regulation of SOX9 (6). ...
An evolutionarily conserved mechanism for cAMP elicited axonal
... inability to regenerate nerve fibers is not set in stone. Instead, it can be unlocked by a second injury in nerves elsewhere in the body, the so-called “peripheral nervous system”. This process relies on an enzyme called DLK, which becomes activated in damaged nerve fibers. But how does DLK ‘sense’ ...
... inability to regenerate nerve fibers is not set in stone. Instead, it can be unlocked by a second injury in nerves elsewhere in the body, the so-called “peripheral nervous system”. This process relies on an enzyme called DLK, which becomes activated in damaged nerve fibers. But how does DLK ‘sense’ ...
Muddashetty RS, Nalavadi VC, Gross C, Yao X, Xing L, Laur O, Warren ST, and Bassell GJ. Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling. Molecular Cell 42: 673-688 (June 2011).
... the mutant mRNA reporter did not differ from wild-type (data not shown). This suggests that a single miR125a target site may be largely responsible for AGO2-mediated translational regulation in the context of the PSD-95 30 UTR. Next, we investigated whether miR-125a had a role in mGluRmediated activ ...
... the mutant mRNA reporter did not differ from wild-type (data not shown). This suggests that a single miR125a target site may be largely responsible for AGO2-mediated translational regulation in the context of the PSD-95 30 UTR. Next, we investigated whether miR-125a had a role in mGluRmediated activ ...
7 - Dynamic Microtubules and the Texture of Plant Cell Walls
... wall was examined by polarized light microscopy. Using this technique, Van Iterson (1937) deduced that Tradescantia stamen hairs would have more or less transverse wall fibers. This is consistent with the biophysical explanation that transverse stress, which is twice the longitudinal force in an exp ...
... wall was examined by polarized light microscopy. Using this technique, Van Iterson (1937) deduced that Tradescantia stamen hairs would have more or less transverse wall fibers. This is consistent with the biophysical explanation that transverse stress, which is twice the longitudinal force in an exp ...
Increased Secretion of Lipoproteins in Transgenic Mice Expressing
... introduce the D374Y mutation and a C-terminal myc2 tag. Transgenic mice that expressed 1 copy of the mutant or wild-type (WT) PCSK9 bacterial artificial chromosome were produced. Human PCSK9 mRNA was expressed at levels comparable to endogenous pcsk9 and with the same tissue specificity. The express ...
... introduce the D374Y mutation and a C-terminal myc2 tag. Transgenic mice that expressed 1 copy of the mutant or wild-type (WT) PCSK9 bacterial artificial chromosome were produced. Human PCSK9 mRNA was expressed at levels comparable to endogenous pcsk9 and with the same tissue specificity. The express ...
Interactions of Elongation Factor 1 Cell Protrusions with F-Actin and
... Bassell et al., 1998). The involvement of EF1␣ in mRNA localization is also suggested from in vivo studies. For example, Bni1p, a yeast protein that is involved in the asymmetric localization of ASH1 mRNA in the daughter cell (Long et al., 1997), has been identified as an EF1␣-binding protein (Umika ...
... Bassell et al., 1998). The involvement of EF1␣ in mRNA localization is also suggested from in vivo studies. For example, Bni1p, a yeast protein that is involved in the asymmetric localization of ASH1 mRNA in the daughter cell (Long et al., 1997), has been identified as an EF1␣-binding protein (Umika ...
Cell fate specification and polarisation in mouse preimplantation
... This thesis may be made available for consultation within the University Library and may be photocopied or lent to other libraries for the purposes of consultation with effect from ………………….. Signed on behalf of the Faculty of Science …………………….. ...
... This thesis may be made available for consultation within the University Library and may be photocopied or lent to other libraries for the purposes of consultation with effect from ………………….. Signed on behalf of the Faculty of Science …………………….. ...
abbs.info - Semantic Scholar
... and spectrum analysis indicated that tryptophan, arginine, cysteine and carboxyl group residues were essential for its hemagglutinating activity. However, they might not be present in the active center, except some carboxyl group residues. AEL also showed significant in vitro antiproliferative activ ...
... and spectrum analysis indicated that tryptophan, arginine, cysteine and carboxyl group residues were essential for its hemagglutinating activity. However, they might not be present in the active center, except some carboxyl group residues. AEL also showed significant in vitro antiproliferative activ ...
Low peak bone mass and attenuated anabolic response to
... bone mass in ColCre;Cx43–/fl mice relative to the wild-type and heterozygous equivalent mice. Histomorphometric analysis evidenced a markedly more reduced trabecular bone mass in ColCre;Cx43–/fl mice, with approximately 40% reduction in bone volume/total volume and more than 50% reduction in osteobl ...
... bone mass in ColCre;Cx43–/fl mice relative to the wild-type and heterozygous equivalent mice. Histomorphometric analysis evidenced a markedly more reduced trabecular bone mass in ColCre;Cx43–/fl mice, with approximately 40% reduction in bone volume/total volume and more than 50% reduction in osteobl ...
RabGDI controls axonal midline crossing by regulating Robo1
... the developing nervous system [34,35]. Robo4 (Magic Roundabout) differs markedly in its domain structure from the other Robos and is expressed exclusively in endothelial cells [36,37]. A role for Robo4 in angiogenesis has been described in mice [38] and zebrafish [39]. In the developing nervous syst ...
... the developing nervous system [34,35]. Robo4 (Magic Roundabout) differs markedly in its domain structure from the other Robos and is expressed exclusively in endothelial cells [36,37]. A role for Robo4 in angiogenesis has been described in mice [38] and zebrafish [39]. In the developing nervous syst ...
Low peak bone mass and attenuated anabolic response to
... bone mass in ColCre;Cx43–/fl mice relative to the wild-type and heterozygous equivalent mice. Histomorphometric analysis evidenced a markedly more reduced trabecular bone mass in ColCre;Cx43–/fl mice, with approximately 40% reduction in bone volume/total volume and more than 50% reduction in osteobl ...
... bone mass in ColCre;Cx43–/fl mice relative to the wild-type and heterozygous equivalent mice. Histomorphometric analysis evidenced a markedly more reduced trabecular bone mass in ColCre;Cx43–/fl mice, with approximately 40% reduction in bone volume/total volume and more than 50% reduction in osteobl ...
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... PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation Hongge Jia, Yajuan Liu, Wei Yan and Jianhang Jia* The seven-transmembrane protein Smoothened (Smo) and Zn-finger transcription factor Ci/Gli are crucial components in Hedgehog (Hh) signal transduction that mediates a ...
... PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation Hongge Jia, Yajuan Liu, Wei Yan and Jianhang Jia* The seven-transmembrane protein Smoothened (Smo) and Zn-finger transcription factor Ci/Gli are crucial components in Hedgehog (Hh) signal transduction that mediates a ...
Nkx2-5 mutation causes anatomic hypoplasia of the cardiac
... Conflict of interest: The authors have declared that no conflict of interest exists. Citation for this article: J. Clin. Invest. 113:1130–1137 (2004). doi:10.1172/JCI200419846. ...
... Conflict of interest: The authors have declared that no conflict of interest exists. Citation for this article: J. Clin. Invest. 113:1130–1137 (2004). doi:10.1172/JCI200419846. ...
Serrated carcinomas form a subclass of colorectal cancer with
... 2003) and that allelic imbalance of the 18q is more common and 5q less common in the serrated adenomas when compared to other polyps (Yashiro et al., 2005). Kambara et al. (2004) found an association between BRAF mutations and DNA methylation in sessile serrated adenomas and suggested that mutations ...
... 2003) and that allelic imbalance of the 18q is more common and 5q less common in the serrated adenomas when compared to other polyps (Yashiro et al., 2005). Kambara et al. (2004) found an association between BRAF mutations and DNA methylation in sessile serrated adenomas and suggested that mutations ...
Mouse Hoxa2 mutations provide a model for microtia and auricle
... External ear abnormalities are frequent in newborns ranging from microtia to partial auricle duplication. Little is known about the molecular mechanisms orchestrating external ear morphogenesis. In humans, HOXA2 partial loss of function induces a bilateral microtia associated with an abnormal shape ...
... External ear abnormalities are frequent in newborns ranging from microtia to partial auricle duplication. Little is known about the molecular mechanisms orchestrating external ear morphogenesis. In humans, HOXA2 partial loss of function induces a bilateral microtia associated with an abnormal shape ...
Functional redundancy of mammalian Polycomb genes
... consistent with very similar posterior transformations of the axial skeleton and severe combined immunodeficiency, which are due to impaired responsiveness to lymphokines such as interleukin 7, observed in Mel18- and Bmi1-deficient mice. However, differences in function between Mel18 and Bmi1 are al ...
... consistent with very similar posterior transformations of the axial skeleton and severe combined immunodeficiency, which are due to impaired responsiveness to lymphokines such as interleukin 7, observed in Mel18- and Bmi1-deficient mice. However, differences in function between Mel18 and Bmi1 are al ...