Fluid Mosaic Model
... Membrane Proteins and their Functions: Proteins determine most of the membranes specific functions Bound to cytoskeleton on cytoplasmic side and ECM on extracellular side ...
... Membrane Proteins and their Functions: Proteins determine most of the membranes specific functions Bound to cytoskeleton on cytoplasmic side and ECM on extracellular side ...
Lecture 02
... In water, the salt NaCl molecule breaks down, and we get charged atoms, called ions: Natrium with a positive charge (Na+) , and chlorine (Cl-) with a negative charge. There are also potassium (K+) ions. Out (+) ...
... In water, the salt NaCl molecule breaks down, and we get charged atoms, called ions: Natrium with a positive charge (Na+) , and chlorine (Cl-) with a negative charge. There are also potassium (K+) ions. Out (+) ...
Diffusion
... Diffusion through protein channels &gating of these channels • Ion channels are integral proteins, tubular pathway all the way from extra cellular to intracellular fluid, substance can move by simple diffusion directly along these channels • These channels are distinguish by two imp characteristics ...
... Diffusion through protein channels &gating of these channels • Ion channels are integral proteins, tubular pathway all the way from extra cellular to intracellular fluid, substance can move by simple diffusion directly along these channels • These channels are distinguish by two imp characteristics ...
bio 342 human physiology
... axons are enveloped by Schwann cells in CNS or Oligodendrocytes in PNS ...
... axons are enveloped by Schwann cells in CNS or Oligodendrocytes in PNS ...
chapter 7 membranes
... C7 Membranes Video Membranes: Held together mostly by hydrophobic interactions Most lipids and some proteins drift randomly in the plane of the membrane Rarely flip-flop from one side to the other Must be fluid to work properly Fluid mosaic model – arrangement of phospholipid layer(s) with ...
... C7 Membranes Video Membranes: Held together mostly by hydrophobic interactions Most lipids and some proteins drift randomly in the plane of the membrane Rarely flip-flop from one side to the other Must be fluid to work properly Fluid mosaic model – arrangement of phospholipid layer(s) with ...
PHYSIOLOGY OF THE NERVE
... As the stimulus intensity is increased (submaximal stimulus), more and more neurons will be brought about into action (recruitment) producing larger AP. The stimulus which excites all neurons is called maximal stimulus. After that, increasing stimulus intensity (supramaximal stimulus) will produce ...
... As the stimulus intensity is increased (submaximal stimulus), more and more neurons will be brought about into action (recruitment) producing larger AP. The stimulus which excites all neurons is called maximal stimulus. After that, increasing stimulus intensity (supramaximal stimulus) will produce ...
Neural_Tissue_notes
... Electrical events of the action potential include resting potential, rising phase of act. pot., falling phase of act. pot., period of hyperpolarization. What properties of the nerve cell membrane cause or account for each of the phases? Voltage-gated Na and K channels play key roles. APs are self-pr ...
... Electrical events of the action potential include resting potential, rising phase of act. pot., falling phase of act. pot., period of hyperpolarization. What properties of the nerve cell membrane cause or account for each of the phases? Voltage-gated Na and K channels play key roles. APs are self-pr ...
Lipids and Membranes, Fall 13--Worksheet Crowe
... Adapted from a POGIL exercise developed by J. Loertscher & V. Minderhout ...
... Adapted from a POGIL exercise developed by J. Loertscher & V. Minderhout ...
Generation and propagation of axon potentials
... In water, the salt NaCl molecule breaks down, and we get charged atoms, called ions: Natrium with a positive charge (Na+) , and chlorine (Cl−) with a negative charge. There are also potassium (K+) ions. Out (+) ...
... In water, the salt NaCl molecule breaks down, and we get charged atoms, called ions: Natrium with a positive charge (Na+) , and chlorine (Cl−) with a negative charge. There are also potassium (K+) ions. Out (+) ...
The Plasma Membrane
... permeable membrane 1. simple diffusion thru membrane small polar molecule that “wiggles” thru nonpolar bilayer when membrane lipids randomly move Aquaporins (leakage channels) unsaturated fatty acid tails & cholesterol leave tiny spaces ...
... permeable membrane 1. simple diffusion thru membrane small polar molecule that “wiggles” thru nonpolar bilayer when membrane lipids randomly move Aquaporins (leakage channels) unsaturated fatty acid tails & cholesterol leave tiny spaces ...
Ian Parker Department of Neurobiology
... Imaging can give information about the AMPLITUDES of signals e.g. Neuronal a4b2 nAChRs show multiple Ca2+ permeability levels whereas muscle abgd nAChRs have (mostly) uniform Ca2+ permeability ...
... Imaging can give information about the AMPLITUDES of signals e.g. Neuronal a4b2 nAChRs show multiple Ca2+ permeability levels whereas muscle abgd nAChRs have (mostly) uniform Ca2+ permeability ...
poster and abstract PDF
... Voltage-gated potassium channels are primary determinants of cellular excitability in the mammalian nervous system. The localization of these channels to distinct cellular compartments influences components of neuronal function, including resting membrane potential, action potential characteristics ...
... Voltage-gated potassium channels are primary determinants of cellular excitability in the mammalian nervous system. The localization of these channels to distinct cellular compartments influences components of neuronal function, including resting membrane potential, action potential characteristics ...
厦门大学细胞生物学课程试卷
... transduction, endocytosis and cholesterol trafficking. （2） Proteasome (4) A: Large protein complex in the cytosol with proteolytic activity that is responsible for degrading proteins that have been marked for destruction by ubiquitylation or by some other means. （3） Endomembrane system (4) A: the st ...
... transduction, endocytosis and cholesterol trafficking. （2） Proteasome (4) A: Large protein complex in the cytosol with proteolytic activity that is responsible for degrading proteins that have been marked for destruction by ubiquitylation or by some other means. （3） Endomembrane system (4) A: the st ...
Human Physiology
... 2.2 Facilitated diffusion through channel 2.2.1 Voltage-gated ion channel 2.2.2 Chemically-gated ion channel 2.2.3 Mechanically-gated ion channel 2.2.4 Water channel ...
... 2.2 Facilitated diffusion through channel 2.2.1 Voltage-gated ion channel 2.2.2 Chemically-gated ion channel 2.2.3 Mechanically-gated ion channel 2.2.4 Water channel ...
Biology 212: January 30, 2002
... Note: the sodium gradient isn’t appreciably changed. Even after even many APs, there are still far more sodium ions outside the cell than inside. After that, permeability to sodium ions rapidly decreases again. This is because each channel is programmed to be open for only about 0.5 msec. It the ...
... Note: the sodium gradient isn’t appreciably changed. Even after even many APs, there are still far more sodium ions outside the cell than inside. After that, permeability to sodium ions rapidly decreases again. This is because each channel is programmed to be open for only about 0.5 msec. It the ...
Research Highlights
... objects such as cells, droplets, foams, vesicles and polymers. The flow and the shape of these deformable objects inside a micrometer sized channel are controlled by the fluid pressure, the viscous stresses, and the particular properties of the objects. The hydrodynamic resistance resulting from the ...
... objects such as cells, droplets, foams, vesicles and polymers. The flow and the shape of these deformable objects inside a micrometer sized channel are controlled by the fluid pressure, the viscous stresses, and the particular properties of the objects. The hydrodynamic resistance resulting from the ...
042407
... • Types of motion – Lateral diffusion • Moves in same monolayer • mSecond timescale • Lipids and proteins – Flip-flop diffusion • Uncommon unless catalyzed (flippase) • Flippases are very specific – Membrane lipids synthesis and transport – Bacterial plasma membrane phospholipids ...
... • Types of motion – Lateral diffusion • Moves in same monolayer • mSecond timescale • Lipids and proteins – Flip-flop diffusion • Uncommon unless catalyzed (flippase) • Flippases are very specific – Membrane lipids synthesis and transport – Bacterial plasma membrane phospholipids ...
Membrane structure, I
... Become limp or flaccid when lose turgor pressure Plasmolysis - plasma membrane pulls away from cell wall ...
... Become limp or flaccid when lose turgor pressure Plasmolysis - plasma membrane pulls away from cell wall ...
Membrane structure, I
... Become limp or flaccid when lose turgor pressure Plasmolysis - plasma membrane pulls away from cell wall ...
... Become limp or flaccid when lose turgor pressure Plasmolysis - plasma membrane pulls away from cell wall ...
concentration gradient
... 1. The structure of a bimolecular sheet is inherent in the structure of the constituent lipid molecules. 2. The growth of lipid bilayers from phospholipids is a rapid and spontaneous process in aqueous solution. ...
... 1. The structure of a bimolecular sheet is inherent in the structure of the constituent lipid molecules. 2. The growth of lipid bilayers from phospholipids is a rapid and spontaneous process in aqueous solution. ...
membrane notes - hrsbstaff.ednet.ns.ca
... Slide2: Artificial membranes. Phospholipids are amphipathic molecules- they have a hydrophobic and hydrophilic section. When they come in contact with water (since water is polar) the hydrophilic section sticks into water and the hydrophobic section is held away. Please note what we talked about in ...
... Slide2: Artificial membranes. Phospholipids are amphipathic molecules- they have a hydrophobic and hydrophilic section. When they come in contact with water (since water is polar) the hydrophilic section sticks into water and the hydrophobic section is held away. Please note what we talked about in ...
Minerals on the Go
... Rule: Whereas macrominerals (Ca2+, Mg2+, Na+, Cl- etc.) travel in the blood and access cells primarily as free ions, the micronutrients (Cu2+, Zn2+, Fe2+, Mn2,, Se) rely on proteins and other ligands for transport and delivery Rule: Targeting microminerals to select organs and locations within cells ...
... Rule: Whereas macrominerals (Ca2+, Mg2+, Na+, Cl- etc.) travel in the blood and access cells primarily as free ions, the micronutrients (Cu2+, Zn2+, Fe2+, Mn2,, Se) rely on proteins and other ligands for transport and delivery Rule: Targeting microminerals to select organs and locations within cells ...
Model Description Sheet
... with G proteins to activate a signaling cascade that leads to downstream effects including the modulation of various ion channels. The GABAB receptor is a dimer composed of two different subunits (GBR1 and GBR2), each with 7 helices within the membrane and an extracellular domain that binds GABA. On ...
... with G proteins to activate a signaling cascade that leads to downstream effects including the modulation of various ion channels. The GABAB receptor is a dimer composed of two different subunits (GBR1 and GBR2), each with 7 helices within the membrane and an extracellular domain that binds GABA. On ...
Mechanosensitive channels
Mechanosensitive channels or mechanosensitive ion channels are membrane proteins capable of responding to mechanical stress over a wide dynamic range of external mechanical stimuli. They are found in prokaryotes and eukaryotes. The channels vary in selectivity for the permeating ions from nonselective between anions and cations in bacteria, to cation selective allowing passage Ca2+, K+ and Na+ in eukaryotes, and highly selective K+ channels in bacteria and eukaryotes.All organisms, and apparently all cell types, sense and respond to mechanical stimuli. MSCs function as mechanotransducers capable of generating both electrical and ion flux signals as a response to external or internal stimuli. Under extreme turgor in bacteria, non selective MSCs such as MSCL and MSCS serve as safety valves to prevent lysis. In specialized cells of the higher organisms, other types of MSCs are probably the basis of the senses of hearing and touch and sense the stress needed for muscular coordination. However, none of these channels have been cloned. MSCs also allow plants to distinguish up from down by sensing the force of gravity. MSCs are not pressure-sensitive, but sensitive to local stress, most likely tension in the surrounding lipid bilayer.