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HOMEOSTASIS
HOMEOSTASIS

... homeostatic functions including water balance People with adrenal insufficiency: these stresses can cause hypotension, shock and death: must give glucocorticoids, eg for surgery or if have infection, etc. ...
Accumulation and Biotransformation of BDE
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... they are not agonists of the aryl hydrocarbon receptor (AhR).16 Therefore, PBDEs were hypothesized to potentially affect thyroid hormone homeostasis. Concentrations of BDE-47 were negatively correlated with circulating concentrations of free T4 (FT4) in blood plasma of white whales (Delphinapterus le ...
The Endocrine System
The Endocrine System

... •  Develops suddenly, usually before age 15 •  T cell–mediated autoimmune response destroys beta cells ...
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Chapter 21: Blood Vessels and Circulation
Chapter 21: Blood Vessels and Circulation

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Effects of repeated whole-body cold exposures on serum
Effects of repeated whole-body cold exposures on serum

... (fT3, fT4). One group of healthy females (n = 6) was exposed to WS (water 0–2 °C) for 20 s and another group (n = 6) to WBC (air 110 °C) for 2 min, three times a week for 12 weeks. Blood samples used for the hormone measurements were taken on weeks 1, 4 and 12 before and 35 min after the cold expos ...
Henriette Undeutsch – Dissecting New Molecular
Henriette Undeutsch – Dissecting New Molecular

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WebbThesis - VTechWorks
WebbThesis - VTechWorks

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Pathomechanisms of the development of obesity in some
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... can contribute to weight gain even when levels of thyroid stimulating hormone (TSH) are normal [22, 23]. Others believe that increased weight is the primary reason for the hormonal disorders observed in thyroid diseases [23–26]. Studies have shown that even slight disturbances in thyroid functioning ...
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Parathyroid glands produce parathyroid hormone, which

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1 Growth Hormone Treatment of Adults with Prader Willi Syndrome
1 Growth Hormone Treatment of Adults with Prader Willi Syndrome

... edema (5 patients) was the most serious treatment emergent adverse event; one patient withdrew from the study because of myalgias associated with lower leg swelling. There was no other evidence of fluid retention for these or any other subjects at baseline or during the study. Baseline cardiac ultra ...
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multiple pituitary hormone deficiencies (MPHD)
multiple pituitary hormone deficiencies (MPHD)

... the gonadotrophins. More details about these hormones are given in booklet No.3 (Puberty and the Growth Hormone Deficient Child). In children with GnRH insufficiency which started before birth, the diagnosis can often be made from signs such as a very small penis (micropenis) and both testes having ...
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... known thyroid system agonists and antagonists [6,29]. In this study, an alternative testing protocol for a Xenopus metamorphosis assay (XEMA) was developed specifically to address ED effects on the thyroid system. During test development, special emphasis was placed on the ability of the test protoc ...
05. Assessment of age dependent reference range of thyrotropin
05. Assessment of age dependent reference range of thyrotropin

... 0.4–2.5 µIU/mL, because research had shown that adults with an initially measured thyrotropin level of over 2.0 µIU/mL had an increased odds ratio of developing hypothyroidism over the following 20 years, especially if thyroid antibodies were elevated. Our present studies have suggested that thyrotr ...
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... – When blood glucose levels fall,  cells  the amount of glucagon in the blood – The surge of glucagon stimulates liver to release glucose stores by the breakdown of glycogen into ...
138 Hormones and the Body
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... (T3 , or triiodothyronine, contains three iodine atoms, while T4  contains four iodine atoms.) If an iodine deficiency occurs, the body cannot make sufficient thyroid hormones, resulting in hypothyroidism. The hypothalamus senses low levels of circulating thyroid hormone and synthesizes TRH in respo ...
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... REC:Post-operative diagnostic radioiodine whole-body scans may be useful when the extent of the thyroid remnant or residual disease cannot be accurately ascertained from the surgical report or neck ultrasonography, and when the results may alter the decision to treat, or the activity of RAI that is ...
Chapter 39 Endocrine and Reproductive Systems, TE
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Hypothalamus - pituitary
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... GH increases fat utilization for energy: • It causes release of fatty acids from adipose tissue (increases the concentration of FFA in the body fluids) • It also causes increased convertion of FFA to acetylcoenzyme A (acetyl-CoA) with subsequent utilization of this for energy (ATP) • Excessive amou ...
Nerve activates contraction
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... •Growth hormone (GH) disorders •Pituitary dwarfism  results from hyposecretion of GH during childhood •Body proportions are fairly normal, but the person is a living minaiture (4 ft. max) •Gigantism  results from hypersecretion of GH during childhood •Anywhere between 8 and 9 ft. is common •Acrome ...
endocrine dysfunctions in tuberculosis
endocrine dysfunctions in tuberculosis

... Autopsy series in 1800’s found the incidence of tuberculosis ranged from 38% to more than 50% in subjects with diabetes [1]. However, in the later series, it was found that the incidence of pulmonary tuberculosis in diabetics was 10 times more than that in non-diabetics [56]. Even as large a number ...
Fatigue and TSH Levels in Hypothyroid Patients
Fatigue and TSH Levels in Hypothyroid Patients

... reductions in TSH levels. Those subjects reporting relief from fatigue tended to be males (p = 0.003), had lower TSH levels at follow-up (p < 0.001), had larger TSH differences from baseline (p =0.007), and had a primary diagnosis of acquired hypothyroidism (p < 0.001). Females were 2.9 times more l ...
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Hyperthyroidism



Hyperthyroidism, also known as over active thyroid and hyperthyreosis, is the condition that occurs due to excessive production of thyroid hormone by the thyroid gland. Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism. Some, however, use the terms interchangeably. Signs and symptoms vary between people and may include irritability, muscle weakness, sleeping problems, a fast heartbeat, poor tolerance of heat, diarrhea, enlargement of the thyroid, and weight loss. Symptoms are typically less in the old and during pregnancy. An uncommon complication is thyroid storm in which an event such as an infection results in worsening symptoms such as confusion and a high temperature and often results in death. The opposite is hypothyroidism, when the thyroid gland does not make enough thyroid hormone.Graves' disease is the cause of about 50% to 80% of case of hyperthyroidism in the United States. Other causes include multinodular goiter, toxic adenoma, inflammation of the thyroid, eating too much iodine, and too much synthetic thyroid hormone. A less common cause is a pituitary adenoma. The diagnosis may be suspected based on signs and symptoms and then confirmed with blood tests. Typically blood tests show a low thyroid stimulating hormone (TSH) and raised T3 or T4. Radioiodine uptake by the thyroid, thyroid scan, and TSI antibodies may help determine the cause.Treatment depends partly on the cause and severity of disease. There are three main treatment options: radioiodine therapy, medications, and thyroid surgery. Radioiodine therapy involves taking iodine-131 by mouth which is then concentrated in and destroys the thyroid over weeks to months. The resulting hypothyroidism is treated with synthetic thyroid hormone. Medications such as beta blockers may control the symptoms and anti-thyroid medications such as methimazole may temporarily help people while other treatments are having effect. Surgery to remove the thyroid is another option. This may be used in those with very large thyroids or when cancer is a concern. In the United States hyperthyroidism affects about 1.2% of the population. It occurs between two and ten times more often in women. Onset is commonly between 20 and 50 years of age. Overall the disease is more common in those over the age of 60 years.
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