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Thyroid hormones
Thyroid hormones

... • 1. Growth Hormone (GH or somatotropin) • GH produced by somatotropic cells of the anterior lobe • Stimulates most cells, but target bone and skeletal muscle • Stimulates the liver and other tissues to secrete insulin-like growth factor I (IGF-I or somatomedin) • IGF-I stimulates proliferation of c ...
Slide - Texas Tech University Departments
Slide - Texas Tech University Departments

... decreased expression of TRH mRNA in the hypothalamus.6,7 A tissue specific increase in type 3 deiodinase (Dio3) activity8, as observed in consumptive hypothyroidism, combined with decreased activity of type 1 deiodinase (Dio1)9,10 results in inactivation of T4 into rT3 and reduced synthesis and incr ...
Hypothalamus and Pituitary
Hypothalamus and Pituitary

... hypothalamus-pituitary unit reflects this relationship. • The pituitary gland lies in a pocket of bone at the base of the brain, just below the hypothalamus to which it is connected by a stalk containing nerve fibers and blood vessels. The pituitary is composed to two lobes-- anterior and posterior ...
MEN1 - NET Patient Foundation
MEN1 - NET Patient Foundation

... Growths in the parathyroid glands resulting in hyperparathyriodism (high level of parathyroid hormone PTH) occur in more than 90% (9 out of 10) of MEN1 patients. The parathyroid glands lie just behind or are sometimes contained within the thyroid in the neck, although there are occasionally extra gl ...
effects-of-the-envir.. - Thyroid Disease Manager
effects-of-the-envir.. - Thyroid Disease Manager

... elevated.60a The elevation of TRH was accompanied by normal levels of proTRH mRNA and decreased pituitary TSH; it was suggested that this represented decreased TRH release. 60a In a different study of starved rats, the hypothalamic proTRH mRNA and the TRH content were both decreased,60b but these ef ...
Effects Of The Environment, Chemicals And Drugs On Thyroid
Effects Of The Environment, Chemicals And Drugs On Thyroid

... elevated.60a The elevation of TRH was accompanied by normal levels of proTRH mRNA and decreased pituitary TSH; it was suggested that this represented decreased TRH release. 60a In a different study of starved rats, the hypothalamic proTRH mRNA and the TRH content were both decreased,60b but these ef ...
The Endocrine System - Ms. Cox, Holy Name Central Catholic High
The Endocrine System - Ms. Cox, Holy Name Central Catholic High

... tissue isthmus -Produces two hormones 1. Thyroid hormone (to body tissues for controlling growth, development, + energy utilization) 2. Calcitonin-regulates amount of blood calcium levels in the body ...
hypthalamus and pitutary glands
hypthalamus and pitutary glands

... – may result from a pituitary tumour – principal symptoms are infertility and menstrual complaints – in men, decreased libido, – inadequate sperm production and impotence, whereas in women, there may be a complete lack of menstruation – inappropriate (non-pregnant) milk production Dr. M. Alzaharna ( ...
Endocrine Physiology
Endocrine Physiology

... cell whose action addresses the biological need. Key features of this stimulus response system are: ...
Title page Title: Thyroid-stimulating hormone reference range and
Title page Title: Thyroid-stimulating hormone reference range and

... TSH reference range would be over time reduced from the current 4.0 – 4.5 mU/L to 2.5 ...
The newborn thyroid stimulating hormone levels in
The newborn thyroid stimulating hormone levels in

... related to neonatal thyroid function, as measured by neonatal TSH levels. Therefore, careful consideration of these factors should be drawn while assessing blood spot TSH levels and providing antenatal care. Key words: pregnancy, blood spot thyroid stimulating hormone (TSH), newborn screening, mater ...
Parathyroid - Dartmouth
Parathyroid - Dartmouth

... • The parathyroid glands develop at 6 weeks and migrate caudally at 8 weeks • The paired superior parathyroid glands develop with the thyroid gland from the fourth branchial pouch and are generally consistent in position, residing lateral and posterior to the upper pole of the thyroid at the level o ...
The Adverse Effects of Mild-to-Moderate Iodine Deficiency during
The Adverse Effects of Mild-to-Moderate Iodine Deficiency during

... and the fetus, newborn, and young child are particularly vulnerable to iodine deficiency. The iodine requirement increases during pregnancy and recommended intakes are in the range of 220–250 mg=day. Monitoring iodine status during pregnancy is a challenge. New recommendations from World Health Orga ...
Anterior pituitary insufficiency
Anterior pituitary insufficiency

... • Primary hypothyroidism means decreased secretion of thyroid hormone from the Thyroid gland • Secondary hypothyroidism means deficiency of Anterior pituitary/ Hypothalamic hormone which stimulates production of thyroid hormone from the thyroid gland (defect not in the thyroid gland) ...
Expressing the quantity variants of fibroblast growth factors
Expressing the quantity variants of fibroblast growth factors

... Thyroid hormone is essential for metabolism, nerve excitability and physical development. Congenital hypothyroidism leads to dysfunction of neuronal migration for thyroid hormone deficiency, and even delays psychomotor formation and development in serious congenital hypothyroidism. Congenital hypoth ...
The Endocrine System 2
The Endocrine System 2

... only specific target cells. Hormones, like neurotransmitters, influence their target cells by chemically binding to specific protein receptors. Only the target cells for a given hormone have receptors that bind and recognize that hormone. For example, thyroid-stimulating hormone (TSH) binds to recep ...
THE EFFECT AND DEPENDENCY OF L
THE EFFECT AND DEPENDENCY OF L

... production of thyroid hormones. Two major disorders are hyperthyroidism and hypothyroidism (Porterfield, 1997). Hyperthyroidism, also called Grave’s disease, is characterized by the over production of thyroid hormones (Duncan, 1959). Symptoms of the disorder include palpitation, tachycardia, exophth ...
endocrine system - Northwest ISD Moodle
endocrine system - Northwest ISD Moodle

... 1. Stimulates carbohydrate, lipid & protein metabolism Glucose & fat catabolism ~ energy produced Protein & cholesterol synthesis ~ growth 2. Increases basal metabolic rate & O2 consumption Calorigenic Effect ~ burn calories ~ body heat Promotes normal oxygen use by cells 3. Regulates tissue growth, ...
Relationship between TSH, T4, T3 and Prolactin in overweight and
Relationship between TSH, T4, T3 and Prolactin in overweight and

... to controls[5]. Remarkably, serum androgens correlate with weight not only in PCOS, but also in those with simple obesity[6]. PCOS is believed to be a heterogeneous dysfunction of multifactorial etiology. It can also be linked to primary hypothyroidism in 6 .3% of PCOS patients[7]. The measurement o ...
Maternal thyroid function during gestation is related to breech
Maternal thyroid function during gestation is related to breech

... poor obstetric outcome.14 The cutoff used in the current study to define high TSH (‡90th percentile, 2Æ5 mIU/l) at 36 weeks gestation, was even lower than the cutoff of 3Æ0 mIU/l as recently recommended by the American Endocrine Society in pregnant women with hypothyroidism who are treated with thyr ...
Photosynthesis
Photosynthesis

... Anterior pituitary hormones that affect other glands: Thyroid-Stimulating Hormone (TSH) Adrenocorticotropic Hormone (ACTH) Gonadotropic Hormones ...
endocrine system - Northwest ISD Moodle
endocrine system - Northwest ISD Moodle

... 1. Stimulates carbohydrate, lipid & protein metabolism Glucose & fat catabolism ~ energy produced Protein & cholesterol synthesis ~ growth 2. Increases basal metabolic rate & O2 consumption Calorigenic Effect ~ burn calories ~ body heat Promotes normal oxygen use by cells 3. Regulates tissue growth, ...
Bio 20
Bio 20

... 14) Which of the following is a true statement? A) Sperm have most of their mitochondria in the head. B) The flagellum (tail) of a sperm is essential for ejaculation to occur. C) The head of a sperm contains mostly digestive enzymes for eating a hole in the zona pellucida. D) All of the above E) No ...
Hormones - Castle High School
Hormones - Castle High School

... metabolic rate. Thyroxine regulates cell metabolism by acting as a transcription factor for many genes and is crucial during development. Hypothalamus releases thyrotropinreleasing hormone (TRH), which causes anterior pituitary to secrete thyroidstimulating hormone (TSH). TSH causes the thyroid to p ...
Hormones - Humble ISD
Hormones - Humble ISD

... metabolic rate. Thyroxine regulates cell metabolism by acting as a transcription factor for many genes and is crucial during development. Hypothalamus releases thyrotropinreleasing hormone (TRH), which causes anterior pituitary to secrete thyroidstimulating hormone (TSH). TSH causes the thyroid to p ...
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Hyperthyroidism



Hyperthyroidism, also known as over active thyroid and hyperthyreosis, is the condition that occurs due to excessive production of thyroid hormone by the thyroid gland. Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism. Some, however, use the terms interchangeably. Signs and symptoms vary between people and may include irritability, muscle weakness, sleeping problems, a fast heartbeat, poor tolerance of heat, diarrhea, enlargement of the thyroid, and weight loss. Symptoms are typically less in the old and during pregnancy. An uncommon complication is thyroid storm in which an event such as an infection results in worsening symptoms such as confusion and a high temperature and often results in death. The opposite is hypothyroidism, when the thyroid gland does not make enough thyroid hormone.Graves' disease is the cause of about 50% to 80% of case of hyperthyroidism in the United States. Other causes include multinodular goiter, toxic adenoma, inflammation of the thyroid, eating too much iodine, and too much synthetic thyroid hormone. A less common cause is a pituitary adenoma. The diagnosis may be suspected based on signs and symptoms and then confirmed with blood tests. Typically blood tests show a low thyroid stimulating hormone (TSH) and raised T3 or T4. Radioiodine uptake by the thyroid, thyroid scan, and TSI antibodies may help determine the cause.Treatment depends partly on the cause and severity of disease. There are three main treatment options: radioiodine therapy, medications, and thyroid surgery. Radioiodine therapy involves taking iodine-131 by mouth which is then concentrated in and destroys the thyroid over weeks to months. The resulting hypothyroidism is treated with synthetic thyroid hormone. Medications such as beta blockers may control the symptoms and anti-thyroid medications such as methimazole may temporarily help people while other treatments are having effect. Surgery to remove the thyroid is another option. This may be used in those with very large thyroids or when cancer is a concern. In the United States hyperthyroidism affects about 1.2% of the population. It occurs between two and ten times more often in women. Onset is commonly between 20 and 50 years of age. Overall the disease is more common in those over the age of 60 years.
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