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Cell Communication
Cell Communication

...  Within multicellular organisms, cells must communicate with one another to coordinate their activities  A signal transduction pathway is a series of steps by which a signal on a cell’s surface is converted into a specific cellular response  Signal transduction pathways are very similar in all or ...
Lymphatic System Notes- Chapter 12
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... *Most become _______________ that secrete _____________________ and last _____ * Some become __________________ and cause a _____________ response the 2nd time -T cells become immunocompetent in ________________________ *Cytotoxic T cells- specialized in _______________________________ *____________ ...
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... 3. The nucleus is the control center of cellular activities. DNA is the “boss” of the cell and is passed down from one generation to another. PROKARYOTIC cells such as bacteria have no nucleus but still possess DNA to direct cellular functions. EUKARYOTIC cells have a nucleus which housed the DNA. E ...
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... antigen-presenting B cell • Helper T cell binds to antigen-MHC complex on the B cell • Interleukins stimulate B cell division and ...
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... results about the expression of CD1d and Rae-1. CD1d is constitutively expressed and the higher expression is observed in the subventricular zone (SVZ). A weak expression of Rae-1 is detected solely in the SVZ of normal brain and its expression is strongly induced in the olfactory bulbs after olfact ...
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...  Rh factor incompatibility – Rh- mom w/Rh+ fetus  Mom makes IgG, binds to fetal Rh+ blood, newborn born with anemia because RBCs were destroyed by fetal immune system (also hyperbilirubinemia)  Graves’ disease – antibody binds to TSH receptors and activates them  Myasthenia Gravis – antibody bin ...
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... The agents of IMMSIM behave like cellular automata (a), but they represent all types of cells of the immune system with their specific receptors and paratopes, the antigens and the invading viruses. T cell helps B cell upon antigen binding of the B receptor, leading to the initiation of the humoral ...
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... antigen to specific T cells, triggering the proliferation of effector T cells and subsequently the production of antibodies. Immune T cells and antibodies attack directly or indirectly the antigen. The adaptive immune response is characterized by specificity for the antigen, the ability to respond m ...
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Antibodies (Immunoglobulin)

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Host Parasite - De Anza College

... • Proliferates into clone with same receptor on surface – If T dependent antigen (proteins), T helper cell will activate B cell to produce plasma cells – Some become memory cells for long term immunity – Self tolerance • B & T cells that react with self antigens removed during early development ...
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... in the spleen, the particles are engulfed by macrophages (white blood cells that engulf pathogens and unwanted materials , then send signals to other immune cells to target those materials) so they are recognised as ordinary dying blood cells by the immune system. ...
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... responsible for production of interferon is placed into the genome of bacteria. Why bacteria? Because, bacteria do not have a nucleus. They have a single circular DNA and chromosome does not have to think on which side of cell they will go. So the rate of bacteria fission is rapid, large amounts of ...
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Immunology: Basic Principles of Adaptive Immunity and Immunizations
Immunology: Basic Principles of Adaptive Immunity and Immunizations

... membrane where they become anchored. Here, the peptide and MHC-I/peptide complexes can be recognized by CTLs by way of TCRs and CD8 molecules having a complementary shape. ...
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Polyclonal B cell response



Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.
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