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Evolution of Immune Systems
Evolution of Immune Systems

... Immunity = The ability to differentiate between ‘self’ and ‘non-self’ ...
Immune System
Immune System

...  Abnormal cells –like those with viruses – make MHCs which bind to viral proteins  Those antigens are presented on the surface of the ...
Cells of the Immune System Principles of Immunology 1/26/06
Cells of the Immune System Principles of Immunology 1/26/06

... Monocytes and Macrophages  Large WBCs ...
Immune System Notes
Immune System Notes

... B LYMPHOCYTES (B cells) make ANTIBODIES IMMUNOGLOBULINS (proteins) Antibodies weaken pathogens and mark for phagocytic cells to “eat” 2. CELL-MEDIATED IMMUNE RESPONSE- important in VIRUSES, CANCER, TRANSPLANTS • Uses T LYMPHOCYTES (T cells) • Made in bone marrow; become T cells in thymus 1. CYTOTOXI ...
Chapter 35
Chapter 35

... Complement proteins attack bacteria White cells attack invaders and clean up Walling Off (like clotting) contains the infection ...
Edward Jenner, 1796 - University of California, Los Angeles
Edward Jenner, 1796 - University of California, Los Angeles

... adaptive immunity – just past the the appearance of vertebrates – jawless fish lack RAG and lymphoid organs whereas the cartilagenous fish have a RAG genes and a well developed adaptive immune response ...
Immun System/PART 2 The immune adaptive defense system
Immun System/PART 2 The immune adaptive defense system

... carrying on their surface aspecific antigen receptors recognition sites, all these cells ineract by their cellular activity or by releasing enzymes, immunologically active biochemical elements in collaboration with macrophages to neutralize or kill and destroy the recognized Ag. ...
All normal, healthy body cells have MHC
All normal, healthy body cells have MHC

Origins and means of the immune response
Origins and means of the immune response

... firm adhesion between leucocytes and endothelium ...
IMMUNOLOGY 2010™ Poster Symposia Schedule
IMMUNOLOGY 2010™ Poster Symposia Schedule

... CD8 T Cell Memory and Plasma Cell Responses Chemokines and Their Receptors in Health and Disease Cytokines II: Immunomodulatory Cytokines Effector Cells and Tissue Damage in Autoimmunity Host Defense: Innate Immune Receptors and Signal Transduction Immune Regulation of Host Immunity during Viral Inf ...
Response to Pathogens
Response to Pathogens

... • How does a vaccine activate your immune system? ...
Figure 16.20 Activation of T cells
Figure 16.20 Activation of T cells

Essential Cell Biology
Essential Cell Biology

... cells respond with a normal biological response to the appropriate first messenger. In mutated cells, however, no response was evoked, because the cells lacked the G-protein. The function could be restored by G-protein derived from another tissue such as brain. ...
11.1 HL Immune System Part 1
11.1 HL Immune System Part 1

... • Immunocompetence means they have the ability to recognize one specific antigen ( the bodies antigen or MHC). • Immunocompetent lymphocytes are stored in the lymph nodes. ...
Chapter 51
Chapter 51

... What would happen if an NK cell killed a virally infected target cell by simply causing the cell to burst, releasing all the cell contents into the tissues? (Figure 51.2) Answer: The viruses would be liberated into the body where they could infect numerous additional cells. ...
Viruses (dellpassovoy) - Ms. Pass's Biology Web Page
Viruses (dellpassovoy) - Ms. Pass's Biology Web Page

... Strictly speaking, they should not be considered "living" organisms at all. However, they are more complex than a lifeless collection of macromolecules and they do show one of the most important signs of life: the ability to ...
9B2.1 anti-glass INVESTIGATOR Name Gerald M. Rubin
9B2.1 anti-glass INVESTIGATOR Name Gerald M. Rubin

... nucleus of the developing photoreceptor cells in a sequence that reflects their acquisition of neuronal identity. 9B2.1 gives strong staining of the morphogenetic furrow and all of the cells that arise from the furrow. It works well on Westerns. ...
Cell Parts Worksheet
Cell Parts Worksheet

... 1. Red blood cells are _____________ (size) than an amoeba cell (pg. 265). 2. Cells are the building blocks of _______________ (pg. 265). 3. _________________ fibers make cell walls rigid (fig. 6.8). 4. Hydrogen, Oxygen, Nitrogen, and _______________ are found in life more commonly than in the Earth ...
Big_Idea_2-4D_Immune_Response
Big_Idea_2-4D_Immune_Response

... does not involve antibodies but rather involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes(a type of white blood cell), and the release of various cytokines in response to an antigen  Cell-mediated immunity is directed ...
Immunity Answers
Immunity Answers

... What is meant by “herd immunity”?  Herd immunity occurs when a large number of people are vaccinated at the same time. This prevents the pathogen from being transmitted within the population because there are no longer any host individuals who act as reservoirs of infection. ...
投影片 1
投影片 1

... http://www.biochemweb.org/neutrophil.shtml ...
TAKS Obj 2 -BIOLOGY
TAKS Obj 2 -BIOLOGY

... inflammatory response (swelling, redness due to histamine release), fever, white blood cells such as phagocytes and macrophages destroying the pathogens and infected tissue cells. ...
The spreading out of particles from an area of high concentration to
The spreading out of particles from an area of high concentration to

... A way to show the genotype of offspring from genetic crosses. Dominant and recessive alleles are identified using capital and ...
A41-Immune Response
A41-Immune Response

... Immune Response 2nd line of defense (nonspecific): increased body temperature (fever) to create conditions unsuitable for pathogen growth; increased blood flow to injured or infected site resulting in inflammation; blood brings white blood cells called macrophages that engulf and kill pathogens ...
1. dia
1. dia

... Normal tissue cells do not express MHC class II NO SIGNAL 1. for CD4+ Th activation Normal tissue cells do not express co-stimulatory molecules and do not produce T cell differentiating cytokines NO SIGNAL 2. for CD4+ Th activation Migration of naive T lymphocytes to normal tissues is limited Antige ...
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Polyclonal B cell response



Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.
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