Cannabinoid receptors in microglia of the central nervous system
... migrate and proliferate during and after injury and inflammation [22–25]. Once activated, they produce various cytokines including interleukin-1 (IL-1), IL-6, and tumor necrosis factor-␣ (TNF-␣) and express major histocompatibility complex classes I and II antigens and the complement receptor, CR3. ...
... migrate and proliferate during and after injury and inflammation [22–25]. Once activated, they produce various cytokines including interleukin-1 (IL-1), IL-6, and tumor necrosis factor-␣ (TNF-␣) and express major histocompatibility complex classes I and II antigens and the complement receptor, CR3. ...
... Anti-Borrelia burgdorferi immunoglobulin seroprevalence in pulmonary sarcoidosis: a negative report H. Martens*, B. Zöllner**, G. Zissel*, D. Burdon*, M. Schlaak*, J. Müller-Quernheim* Anti-Borrelia burgdorferi immunoglobulin seroprevalence in pulmonary sarcoidosis: a negative report. H. Martens, B. ...
Th1, Th2 and Treg associated factors in relation to allergy Camilla Janefjord
... ISSN: 0345-0082 Paper I and II have been reprinted with permission from Blackwell Publishing Ltd. Printed in Sweden by LiU-Tryck, Linköping 2006 ...
... ISSN: 0345-0082 Paper I and II have been reprinted with permission from Blackwell Publishing Ltd. Printed in Sweden by LiU-Tryck, Linköping 2006 ...
THE HLA SYSTEM
... set up an immune response that will recognize and destroy cells with this same foreign antigen/HLA complex when next encountered. The exact mode of action of HLA Class I and HLA Class II antigens is different in this process. HLA Class I molecules, by virtue of their presence on all nucleated cells, ...
... set up an immune response that will recognize and destroy cells with this same foreign antigen/HLA complex when next encountered. The exact mode of action of HLA Class I and HLA Class II antigens is different in this process. HLA Class I molecules, by virtue of their presence on all nucleated cells, ...
Total white blood cell counts and LPS-induced TNFa
... conditions. For the post-implantation phase of pregnancy, this is once more stressed by the increased numbers of WBC and PMN. # 2003 Elsevier Science Ireland Ltd. All rights reserved. Keywords: Monocytes; TNFa; White blood cells; Progesterone; Placenta; Pregnancy ...
... conditions. For the post-implantation phase of pregnancy, this is once more stressed by the increased numbers of WBC and PMN. # 2003 Elsevier Science Ireland Ltd. All rights reserved. Keywords: Monocytes; TNFa; White blood cells; Progesterone; Placenta; Pregnancy ...
Immunology of Viral Disease, How to Curb Persistent Infection Simone C. Zimmerli
... Publication #2: The second article (section 4.2, page 81) explores new strategies to trigger CD8 T cell immunity against specific HIV-1 proteins believed to be processed and exposed as "infection signal" at the surface of infected cells. Such signals consist of peptide fragments (813 amino acids) or ...
... Publication #2: The second article (section 4.2, page 81) explores new strategies to trigger CD8 T cell immunity against specific HIV-1 proteins believed to be processed and exposed as "infection signal" at the surface of infected cells. Such signals consist of peptide fragments (813 amino acids) or ...
Filip Čulo
... adoptive immunochemotherapy malignant tumors. With collaborators he showed that tumor cells which escape the direct killing with sublethal dose of cyclophosphamide are, for about three weeks, more sensitive to an immunological attack of immunological cells. When these cells are transferred into norm ...
... adoptive immunochemotherapy malignant tumors. With collaborators he showed that tumor cells which escape the direct killing with sublethal dose of cyclophosphamide are, for about three weeks, more sensitive to an immunological attack of immunological cells. When these cells are transferred into norm ...
Type I interferons produced by hematopoietic cells protect
... NK cells are not required for clearance of reovirus T1L NK cells play an essential role in the early response to many, but not all viral infections (25). These cells are particularly important components of host defense against members of the herpesvirus family, several of which have developed strat ...
... NK cells are not required for clearance of reovirus T1L NK cells play an essential role in the early response to many, but not all viral infections (25). These cells are particularly important components of host defense against members of the herpesvirus family, several of which have developed strat ...
PHS 398 (Rev. 9/04), Biographical Sketch Format Page
... Homann, D., T. Dyrberg, J. Petersen, M.B.A. Oldstone, M.G. von Herrath. Insulin in oral immune "tolerance": A one amino acid change in the B-chain makes the difference. J. Immunol. 163:1833-1838 (1999) Oldstone, M.B.A., H. Lewicki, D. Thomas, A. Tishon, D. White, S. Dales, J. Patterson, M. Mancheste ...
... Homann, D., T. Dyrberg, J. Petersen, M.B.A. Oldstone, M.G. von Herrath. Insulin in oral immune "tolerance": A one amino acid change in the B-chain makes the difference. J. Immunol. 163:1833-1838 (1999) Oldstone, M.B.A., H. Lewicki, D. Thomas, A. Tishon, D. White, S. Dales, J. Patterson, M. Mancheste ...
Candida
... model suggests that a similar acute PMN migration into the vagina is mediated by chemotactic S100A8 and S100A9 alarmins produced by vaginal epithelial cells in response to Candida. Based on the putative role for the Th17 response in mucosal candidiasis as well as S100 alarmin induction, this study a ...
... model suggests that a similar acute PMN migration into the vagina is mediated by chemotactic S100A8 and S100A9 alarmins produced by vaginal epithelial cells in response to Candida. Based on the putative role for the Th17 response in mucosal candidiasis as well as S100 alarmin induction, this study a ...
Immunoglobulin and T cell receptor genes: IMGT® and
... immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility (MH), and proteins of the IgSF and MhSF superfamilies. IMGT® has been built on the IMGTONTOLOGY axioms and concepts, which bridged the gap between genes, sequences, and three-dimensional (3D) structures.The concepts ...
... immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility (MH), and proteins of the IgSF and MhSF superfamilies. IMGT® has been built on the IMGTONTOLOGY axioms and concepts, which bridged the gap between genes, sequences, and three-dimensional (3D) structures.The concepts ...
Licentiate thesis from the Department of Immunology,
... innate response to control pathogen proliferation and spread until the adaptive response of specific T and B cells has fully developed. The detection of pathogens is first carried out by sentinel cells of the innate immune system, such as macrophages and dendritic cells, located in tissues that are ...
... innate response to control pathogen proliferation and spread until the adaptive response of specific T and B cells has fully developed. The detection of pathogens is first carried out by sentinel cells of the innate immune system, such as macrophages and dendritic cells, located in tissues that are ...
Amniotic Derived Stem Cells: Role and Function in Regenerative
... gestational age and fetal development. In most conditions the amount of amniotic fluid cells increases as gestation advances. If a fetal disease is present amniotic fluid cell counts can be very reduced or abnormally elevated. Based on morphological growth characteristics the amniotic cells are clas ...
... gestational age and fetal development. In most conditions the amount of amniotic fluid cells increases as gestation advances. If a fetal disease is present amniotic fluid cell counts can be very reduced or abnormally elevated. Based on morphological growth characteristics the amniotic cells are clas ...
Yeast Nutrients Make Fermentations Better
... Phosphorus is an essential component of deoxyribonucleic acid (DNA), as well as phospholipids within cell membranes. 3-5% of the dry cell weight material of yeast is phosphorus, most of which is stored in vacuoles inside the yeast cell. If phosphate is lacking, fermentation troubles can arise due to ...
... Phosphorus is an essential component of deoxyribonucleic acid (DNA), as well as phospholipids within cell membranes. 3-5% of the dry cell weight material of yeast is phosphorus, most of which is stored in vacuoles inside the yeast cell. If phosphate is lacking, fermentation troubles can arise due to ...
Inflammation, Immune Activation, and HIV
... The table below lists key chemical messengers contributing to inflammation that are discussed in this article; the immune system uses hundreds of signaling chemicals and this list is by no means complete. Some of these chemicals build up in the bloodstream and can be measured in laboratory tests as ...
... The table below lists key chemical messengers contributing to inflammation that are discussed in this article; the immune system uses hundreds of signaling chemicals and this list is by no means complete. Some of these chemicals build up in the bloodstream and can be measured in laboratory tests as ...
Gut Microbiota_ The Conductor in the Orchestra of Immune
... components.40–42 Elimination of the penetrant bacteria would thus lead to the induction of antigen presentation and processing molecules, innate and adaptive constituents that reside in the lamina propria. Hence, this initial close but regulated contact could benefit the host by strengthening its gut ...
... components.40–42 Elimination of the penetrant bacteria would thus lead to the induction of antigen presentation and processing molecules, innate and adaptive constituents that reside in the lamina propria. Hence, this initial close but regulated contact could benefit the host by strengthening its gut ...
Piperine inhibits cytokine production by human peripheral blood
... significantly inhibited the proliferation of PHA-stimulated PBMCs. Actinomycin D is primarily used to inhibit transcription. It is also widely used as a clinical anti-tumor drug. We compared piperine’s effect on PBMC proliferation with that of actinomycin D. When activated PBMCs were cultured with 1 ...
... significantly inhibited the proliferation of PHA-stimulated PBMCs. Actinomycin D is primarily used to inhibit transcription. It is also widely used as a clinical anti-tumor drug. We compared piperine’s effect on PBMC proliferation with that of actinomycin D. When activated PBMCs were cultured with 1 ...
Basophils contribute to TH2-IgE responses in vivo via IL
... undergo differentiation in situ1,7. Thus, normally, mature mast cells are not found in the circulation. In contrast, basophils are rare circulating granulocytes that originate from progenitors in the bone marrow. Basophils constitute less than 1% of blood leukocytes and are normally not present in t ...
... undergo differentiation in situ1,7. Thus, normally, mature mast cells are not found in the circulation. In contrast, basophils are rare circulating granulocytes that originate from progenitors in the bone marrow. Basophils constitute less than 1% of blood leukocytes and are normally not present in t ...
An evaluation of the anti-inflammatory properties
... 3.3 Effect of potassium humate on mononuclear human lymphocytes in vitro..............62 3.4 The effect of potassium humate on TNF-α production on resting and PHA stimulated human lymphocytes in vitro ...............................................63 3.5 The effect of potassium humate on IL-1β produ ...
... 3.3 Effect of potassium humate on mononuclear human lymphocytes in vitro..............62 3.4 The effect of potassium humate on TNF-α production on resting and PHA stimulated human lymphocytes in vitro ...............................................63 3.5 The effect of potassium humate on IL-1β produ ...
Salp15 Binding to DC-SIGN Inhibits Cytokine Expression by Impairing both Nucleosome
... control) and Salp15. As negative control beads we used antibody (anti-V5) coated beads. Immature DCs were incubated with the ligands and binding was measured by FACS analysis. Specificity was determined by preincubation of DCs with EDTA or mannan (significance determined by a two-sided one way ANOVA ...
... control) and Salp15. As negative control beads we used antibody (anti-V5) coated beads. Immature DCs were incubated with the ligands and binding was measured by FACS analysis. Specificity was determined by preincubation of DCs with EDTA or mannan (significance determined by a two-sided one way ANOVA ...
Mitochondrial dynamics and the cell cycle
... in Arabidopsis during the cell cycle. During the G1/S stages of the cell cycle in the shoot apical meristem, there is one large mitochondria found at the end of the nucleus with additional small round shaped mitochondria in other parts of the cell. During the G2, the large and small mitochondria dou ...
... in Arabidopsis during the cell cycle. During the G1/S stages of the cell cycle in the shoot apical meristem, there is one large mitochondria found at the end of the nucleus with additional small round shaped mitochondria in other parts of the cell. During the G2, the large and small mitochondria dou ...
Product List Autobio Diagnostics
... AFP CLIA for the quantitative determination of alpha feto-Protein in human serum. CEA CLIA for the quantitative determination of carcinoembryonic antigen in human serum. PSA CLIA for the quantitative determination of prostate specific antigen (PSA) in Human Serum. f-PSA CLIA for the quantitative det ...
... AFP CLIA for the quantitative determination of alpha feto-Protein in human serum. CEA CLIA for the quantitative determination of carcinoembryonic antigen in human serum. PSA CLIA for the quantitative determination of prostate specific antigen (PSA) in Human Serum. f-PSA CLIA for the quantitative det ...
Th17 Cell Frequency and IL-17 Concentration Correlate
... egeneration of the human intervertebral disk (IVD) is a widespread and debilitating disorder characterized by pronounced anatomic and biological changes in a process that is strongly associated with aging.1 Low back pain in humans, which is an increasingly common and costly health problem, is mainly ...
... egeneration of the human intervertebral disk (IVD) is a widespread and debilitating disorder characterized by pronounced anatomic and biological changes in a process that is strongly associated with aging.1 Low back pain in humans, which is an increasingly common and costly health problem, is mainly ...
3D Structure - Canadian Bioinformatics Workshops
... Membrane or Water Soluble? • Most protein scientists prefer to work with water soluble proteins or domains • Membrane proteins are very difficult to clone, express and purify and special techniques must be used • Potential problems can be avoided by knowing whether the protein contains one or more ...
... Membrane or Water Soluble? • Most protein scientists prefer to work with water soluble proteins or domains • Membrane proteins are very difficult to clone, express and purify and special techniques must be used • Potential problems can be avoided by knowing whether the protein contains one or more ...
Polyclonal B cell response
Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.