Program - Facultatea de Biologie - Universitatea „Alexandru Ioan
... reaching the maximum levels after about 11 hours of growth. Two other products could be detected by HPLC, one which was identified as the nicotineblue (NB) pigment and a second a still unknown end-product. ...
... reaching the maximum levels after about 11 hours of growth. Two other products could be detected by HPLC, one which was identified as the nicotineblue (NB) pigment and a second a still unknown end-product. ...
Lymphatic System PowerPoint
... Functions of Lymphocytes • Cell Mediated Immunity ( T Lymphocytes) – Lymphokines - are produced by T cells to direct the immune system response by signaling between its cells. Lymphokines attract other immune cells, like macrophages and other lymphocytes, to an infected site and to help attack the ...
... Functions of Lymphocytes • Cell Mediated Immunity ( T Lymphocytes) – Lymphokines - are produced by T cells to direct the immune system response by signaling between its cells. Lymphokines attract other immune cells, like macrophages and other lymphocytes, to an infected site and to help attack the ...
Immunological Memory And Role Of T Lymphocytes During Viral
... encounter with a pathogen and to respond more rapidly and effectively following re-infection with the same pathogen. This process named “immunological memory” is at the basis of vaccination, a practice that has successfully eradicated deadly viruses such as variola virus (small pox) and which to dat ...
... encounter with a pathogen and to respond more rapidly and effectively following re-infection with the same pathogen. This process named “immunological memory” is at the basis of vaccination, a practice that has successfully eradicated deadly viruses such as variola virus (small pox) and which to dat ...
Immunology for Anaesthetists Part 1 - Basic Immunology
... Activation of naïve T-cells occurs in a process called ‘antigen presentation’. Dendritic cells and macrophages involved in the innate response migrate to lymphoid tissue where they present antigen in association with MHC, this is why they are called antigen presenting cells (APCs). CD8+ T-cells are ...
... Activation of naïve T-cells occurs in a process called ‘antigen presentation’. Dendritic cells and macrophages involved in the innate response migrate to lymphoid tissue where they present antigen in association with MHC, this is why they are called antigen presenting cells (APCs). CD8+ T-cells are ...
GM.011 Immune A AB - Anti IgG Gel Card
... >1.0%) may result in false-positive or false-negative reactions. 8.5.4 Anomalous results may be caused by fresh serum, fibrin or particulate matter in serum or plasma, or red cells that stick to the sides of the microtube. Use of EDTA plasma will minimize this problem. 8.5.5 Adherence to the manufac ...
... >1.0%) may result in false-positive or false-negative reactions. 8.5.4 Anomalous results may be caused by fresh serum, fibrin or particulate matter in serum or plasma, or red cells that stick to the sides of the microtube. Use of EDTA plasma will minimize this problem. 8.5.5 Adherence to the manufac ...
ImmunLec22
... • Took Sing Sing prisoners (male) and injected them with different blood types. • Identified a D antigen, a minor antigen that is T cell dependent and evokes a Ig G response, but only if Ig M to major blood group antigens hasn’t occurred. • Developed Rhogam , recombinant Ig G to D antigen. Injected ...
... • Took Sing Sing prisoners (male) and injected them with different blood types. • Identified a D antigen, a minor antigen that is T cell dependent and evokes a Ig G response, but only if Ig M to major blood group antigens hasn’t occurred. • Developed Rhogam , recombinant Ig G to D antigen. Injected ...
幻灯片 1
... Dominant Epitope Epitope in primary immune response Cryptic Epitope Epitope in continuous immune response ...
... Dominant Epitope Epitope in primary immune response Cryptic Epitope Epitope in continuous immune response ...
Chapter 12: The Cell Cycle Asexual Cell Division • Creates
... Cells stop dividing when they touch (form single layer in culture) Remove neighbors = division Membrane proteins b/w cells interact to inhibit division o Anchorage Dependence Most animal cells only divide if anchored to substratum Typically ECM of a tissue Control seems to come from conn ...
... Cells stop dividing when they touch (form single layer in culture) Remove neighbors = division Membrane proteins b/w cells interact to inhibit division o Anchorage Dependence Most animal cells only divide if anchored to substratum Typically ECM of a tissue Control seems to come from conn ...
Example Project Descriptions
... They have to decide what type of cell they want to be and never ask you any questions! What makes a red blood cell a red blood cell and a skin cell a skin cell? By switching on different genes, a cell is able to become specialised so that it is able to perform a specific task within your body. A red ...
... They have to decide what type of cell they want to be and never ask you any questions! What makes a red blood cell a red blood cell and a skin cell a skin cell? By switching on different genes, a cell is able to become specialised so that it is able to perform a specific task within your body. A red ...
Hematopoiesis Hematopoiesis Hematopoiesis Apoptosis
... • Lack TCR of T cells or sIg of B cells • Unique surface markers: CD16 (FcγRIII) and CD56 • Action similar to Tc (CD8+) cells • Role: destroys tumor cells and virus-infected cells • Recognition due to altered expression of MHC-I and ADCC (Ab-dependent cell cytotoxicity) • NK1-T cell: T cell and NK c ...
... • Lack TCR of T cells or sIg of B cells • Unique surface markers: CD16 (FcγRIII) and CD56 • Action similar to Tc (CD8+) cells • Role: destroys tumor cells and virus-infected cells • Recognition due to altered expression of MHC-I and ADCC (Ab-dependent cell cytotoxicity) • NK1-T cell: T cell and NK c ...
Virus Notes - ScienceCo
... o The third line of defence is specific to the pathogen responsible for infection. o This line of defence is triggered by the presence of specific substances known as antigens. Antigens can be surface proteins, lipids, or carbohydrates found on viruses, bacteria, or other pathogens. o The key to thi ...
... o The third line of defence is specific to the pathogen responsible for infection. o This line of defence is triggered by the presence of specific substances known as antigens. Antigens can be surface proteins, lipids, or carbohydrates found on viruses, bacteria, or other pathogens. o The key to thi ...
Defense Lecture Study ppt File
... – Lymphocytes produce gamma (), or immune, interferon – Most other WBCs produce alpha () interferon – Fibroblasts produce beta () interferon – Interferons also activate macrophages and mobilize NKs ...
... – Lymphocytes produce gamma (), or immune, interferon – Most other WBCs produce alpha () interferon – Fibroblasts produce beta () interferon – Interferons also activate macrophages and mobilize NKs ...
Membrane Receptors for Antigen
... called HLA-A, HLA-B and HLA-C (HLA stands for Human Leukocyte Antigen – they were originally called antigens because animals make antibodies against MHC molecules from different individual) ...
... called HLA-A, HLA-B and HLA-C (HLA stands for Human Leukocyte Antigen – they were originally called antigens because animals make antibodies against MHC molecules from different individual) ...
Slide 1
... Tumours represent the most important of the white cell disorders. They can be divided into three broad categories based on the origin of the tumour cells: 1-Lymphoid neoplasms, which include lymphomas, lymphocytic leukaemia, and plasma cell dyscrasia. 2-Myeloid neoplasms arise from stem cells that n ...
... Tumours represent the most important of the white cell disorders. They can be divided into three broad categories based on the origin of the tumour cells: 1-Lymphoid neoplasms, which include lymphomas, lymphocytic leukaemia, and plasma cell dyscrasia. 2-Myeloid neoplasms arise from stem cells that n ...
Adv Phys Immune System
... normally to have millions of different kinds of antibody molecules in our bodies Each of these has its own uniquely shaped combining sites Antigen binding sites are in variable regions ...
... normally to have millions of different kinds of antibody molecules in our bodies Each of these has its own uniquely shaped combining sites Antigen binding sites are in variable regions ...
Immune System
... – Large lymphocytes (large granular lymphocytes) • Natural killer (NK) cells (CD16, CD56) • Innate immunity to viruses and other intracellular pathogens • Participate in antibody-dependent cell-mediated cytotoxicity (ADCC) ...
... – Large lymphocytes (large granular lymphocytes) • Natural killer (NK) cells (CD16, CD56) • Innate immunity to viruses and other intracellular pathogens • Participate in antibody-dependent cell-mediated cytotoxicity (ADCC) ...
Slide 1
... • Primary therapy is directed at suppressing the patients immune system with corticosteroids – Reports from 1990’s indicate that 80% of responses incomplete or not sustained • The survival in patients who do not respond to steroids is around 10% ...
... • Primary therapy is directed at suppressing the patients immune system with corticosteroids – Reports from 1990’s indicate that 80% of responses incomplete or not sustained • The survival in patients who do not respond to steroids is around 10% ...
Adaptive Immune System Chapter 16
... – IgG–most common (80% of serum antibodies) and longest-lasting antibody – IgA– associated with body secretions, provides nursing newborns some protection against foreign antigens, newborn receives antibodies against antigens that have infected their mothers ...
... – IgG–most common (80% of serum antibodies) and longest-lasting antibody – IgA– associated with body secretions, provides nursing newborns some protection against foreign antigens, newborn receives antibodies against antigens that have infected their mothers ...
Higher Human Biology Unit 4 Pupil Notes Chapter 21 Body defends
... Infected cell undergoes apoptosis This is followed by phagocytosis Cancer cells Other cytotoxic T cells recognise antigens on the surface of cancer cells and attack them Lysis (bursting) of the cancer cells occurs ...
... Infected cell undergoes apoptosis This is followed by phagocytosis Cancer cells Other cytotoxic T cells recognise antigens on the surface of cancer cells and attack them Lysis (bursting) of the cancer cells occurs ...
T cells - apbiostafford
... How is any cell tagged with antigens? • Major histocompatibility (MHC) proteins – proteins which constantly carry bits of cellular material from the cytosol to the cell surface – “snapshot” of what is going on inside cell – give the surface of cells a unique label or “fingerprint” MHC protein ...
... How is any cell tagged with antigens? • Major histocompatibility (MHC) proteins – proteins which constantly carry bits of cellular material from the cytosol to the cell surface – “snapshot” of what is going on inside cell – give the surface of cells a unique label or “fingerprint” MHC protein ...
The Regulatory Network of Lymphopoiesis in
... Once B cells have completed their development in the bone marrow, they move to the bloodstream as naive B lymphocytes. When activated, these cells differentiation towards effector plasma cells (PCs), which secrete soluble antibodies. The modeling of regulatory networks has been shown to be an adequa ...
... Once B cells have completed their development in the bone marrow, they move to the bloodstream as naive B lymphocytes. When activated, these cells differentiation towards effector plasma cells (PCs), which secrete soluble antibodies. The modeling of regulatory networks has been shown to be an adequa ...
III. Immunology and Complement
... Produced in response to a wide variety of antigens, including bacteria, viruses and RBC and WBC alloantigens. Coats organisms to enhance phagocytosis by neutrophils and macrophages. Through its ability to cross the placenta, maternal IgG provides the major line of defense against infection for the f ...
... Produced in response to a wide variety of antigens, including bacteria, viruses and RBC and WBC alloantigens. Coats organisms to enhance phagocytosis by neutrophils and macrophages. Through its ability to cross the placenta, maternal IgG provides the major line of defense against infection for the f ...
The Immune System
... involves nonspecific responses to pathogens. Innate immunity consists of external barriers plus internal cellular and chemical defenses • Adaptive immunity, or acquired immunity, develops after exposure to agents such as microbes, toxins, or other foreign substances, and it involves a very specific ...
... involves nonspecific responses to pathogens. Innate immunity consists of external barriers plus internal cellular and chemical defenses • Adaptive immunity, or acquired immunity, develops after exposure to agents such as microbes, toxins, or other foreign substances, and it involves a very specific ...
Cancer immunotherapy
Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.