PowerPoint Presentation: Immune System
... cell, the cytotoxic T cell matures. Then, when the mature cytotoxic T cell encounters its specific target antigen combined with a class I marker protein—for instance, on a body cell that has been infected with a virus—it is ready to attack and kill the target cell. ...
... cell, the cytotoxic T cell matures. Then, when the mature cytotoxic T cell encounters its specific target antigen combined with a class I marker protein—for instance, on a body cell that has been infected with a virus—it is ready to attack and kill the target cell. ...
Ralph Steinman and the Discovery of Dendritic Cells Dec. 7 , 2011
... During the Steady State, Dendritic Cells Induce Tolerance, So That During Infection, Dendritic Cell Maturation Does Not Lead to Autoimmunity and Chronic Inflammation Self and harmless environmental antigens ...
... During the Steady State, Dendritic Cells Induce Tolerance, So That During Infection, Dendritic Cell Maturation Does Not Lead to Autoimmunity and Chronic Inflammation Self and harmless environmental antigens ...
Chapter 21b
... • Several antibodies bind close together on a cellular antigen • Their complement-binding sites trigger complement fixation into the cell’s surface • Complement triggers cell lysis ...
... • Several antibodies bind close together on a cellular antigen • Their complement-binding sites trigger complement fixation into the cell’s surface • Complement triggers cell lysis ...
Lymphocytes
... T cells also can turn still other cells into auxiliary APC's by secreting gamma interferon (e.g. endothelial cells). 3. Subtypes of T cells carry out individual functions. Subtypes of T cells used to be named for their particular functions (“helper cells”, “suppressor cells” etc.) Now they are recog ...
... T cells also can turn still other cells into auxiliary APC's by secreting gamma interferon (e.g. endothelial cells). 3. Subtypes of T cells carry out individual functions. Subtypes of T cells used to be named for their particular functions (“helper cells”, “suppressor cells” etc.) Now they are recog ...
Search for Better Health #2
... The maintenance and repair of body tissues in relation to gene expression: Gene expression refers to the transfer of information from a gene to produce a new protein or RNA. It can occur throughout the life of an organism, specifically for repair and maintenance of tissues. Constitutive genes ar ...
... The maintenance and repair of body tissues in relation to gene expression: Gene expression refers to the transfer of information from a gene to produce a new protein or RNA. It can occur throughout the life of an organism, specifically for repair and maintenance of tissues. Constitutive genes ar ...
Cellular Immune Response
... Immunodeficiency disorders are a group of disorders in which part of the immune system is missing or defective. Causes the body's ability to fight infections to be impaired. Person with an immunodeficiency disorder will have frequent infections that are generally more severe and last ...
... Immunodeficiency disorders are a group of disorders in which part of the immune system is missing or defective. Causes the body's ability to fight infections to be impaired. Person with an immunodeficiency disorder will have frequent infections that are generally more severe and last ...
Vaccine
... A fragment of it can create an immune response. Examples include : the subunit vaccine against Hepatitis B virus that is composed of only the surface proteins of the virus (previously extracted from the blood serum of chronically infected patients, but now produced by recombination of the viral gene ...
... A fragment of it can create an immune response. Examples include : the subunit vaccine against Hepatitis B virus that is composed of only the surface proteins of the virus (previously extracted from the blood serum of chronically infected patients, but now produced by recombination of the viral gene ...
Decoding the Patterns of Self and Nonself by the Innate Immune
... kocytes by monitoring the expression of sialic acids on normal self-tissues and antigens (10). Lack of sialic acid expression on most microorganisms, and in some cases, on virally infected and transformed cells may be recognized as a missing-self signal. Siglecs expressed on macrophages, dendritic c ...
... kocytes by monitoring the expression of sialic acids on normal self-tissues and antigens (10). Lack of sialic acid expression on most microorganisms, and in some cases, on virally infected and transformed cells may be recognized as a missing-self signal. Siglecs expressed on macrophages, dendritic c ...
Morphologic Patterns of Acute Inflammation
... • Influx of other cell types via cytokines • Fibroblast proliferation • Angiogenesis Arsenal of mediators make them ...
... • Influx of other cell types via cytokines • Fibroblast proliferation • Angiogenesis Arsenal of mediators make them ...
The Molecular Nature of Tumorigenesis Molecular aspects of cancer
... for therapeutics. It is recommended that people over the age of fifty take one baby aspirin a day to help reduce their risk of certain cancers and tumor-promoting inflammation. Genome Instability and Mutation Oncogenic processes are facilitated by multiple alterations throughout the cancer genome. C ...
... for therapeutics. It is recommended that people over the age of fifty take one baby aspirin a day to help reduce their risk of certain cancers and tumor-promoting inflammation. Genome Instability and Mutation Oncogenic processes are facilitated by multiple alterations throughout the cancer genome. C ...
DiGeorge`s syndrome
... Lesions can occur at any site in the pathway of B-cell development. B-cell defect could be in any level in the pathway ...
... Lesions can occur at any site in the pathway of B-cell development. B-cell defect could be in any level in the pathway ...
Chapter 21 - next2eden.net
... Which of the following best describes the immune system? a. The set of clearly defined organs that connect structurally to defend the body from pathogens b. The organ set that accumulates pathogens and kills them c. The diverse set of molecules and immune cells that are found in lymphoid tissue and ...
... Which of the following best describes the immune system? a. The set of clearly defined organs that connect structurally to defend the body from pathogens b. The organ set that accumulates pathogens and kills them c. The diverse set of molecules and immune cells that are found in lymphoid tissue and ...
Genetic Disorders
... cascade with their Fc region and initiate activation of the "classical" complement system This results in the killing of bacteria in two ways; First, the binding of the antibody and complement molecules marks the microbe for ingestion by phagocytes in a process called opsonization; Secondly, some co ...
... cascade with their Fc region and initiate activation of the "classical" complement system This results in the killing of bacteria in two ways; First, the binding of the antibody and complement molecules marks the microbe for ingestion by phagocytes in a process called opsonization; Secondly, some co ...
Lymphatic system - Seattle Central
... Lymphatic system A series of highways training centers & checkpoints for our immune cells ...
... Lymphatic system A series of highways training centers & checkpoints for our immune cells ...
Hypersensitivity Reactions
... Defence against variety of intracellular persistent or non-degradable antigens, such as tubercle bacilli. pathogens, including mycobacteria, fungi, and certain parasites, It may also be involved in transplant rejection. Tumour immunity NOTE: In AIDS loss of CD4+ T lymphocytes increased s ...
... Defence against variety of intracellular persistent or non-degradable antigens, such as tubercle bacilli. pathogens, including mycobacteria, fungi, and certain parasites, It may also be involved in transplant rejection. Tumour immunity NOTE: In AIDS loss of CD4+ T lymphocytes increased s ...
Immunogerontology Ed`s update
... robust findings, beyond the fact that the elderly sometimes do not mount quite such high titers of antibodies in response to stimulation. Since the CD28 molecule is used by T-cells to stimulate B-cells, perhaps this is the explanation. However, the most recent big study of vaccine responses in older ...
... robust findings, beyond the fact that the elderly sometimes do not mount quite such high titers of antibodies in response to stimulation. Since the CD28 molecule is used by T-cells to stimulate B-cells, perhaps this is the explanation. However, the most recent big study of vaccine responses in older ...
Licensing opportunity Oral CXCR4 Antagonists Potential in
... Oral One compound in Phase I (others in preclinical) Other CXCR4 antagonists, none approved (most advanced in Ph1/2, Majority of other compounds in development are injectable) ...
... Oral One compound in Phase I (others in preclinical) Other CXCR4 antagonists, none approved (most advanced in Ph1/2, Majority of other compounds in development are injectable) ...
HIV-1 Lifecycle (Assembly and Maturation)
... • HIV life cycle involves transcription of viral RNA into DNA and integration into human genome. • Mutational potential of HIV-1 results in worldwide diversity (subtypes), viral escape from immune response and development of drug resistance. • Viral replication persists throughout infection. • Funda ...
... • HIV life cycle involves transcription of viral RNA into DNA and integration into human genome. • Mutational potential of HIV-1 results in worldwide diversity (subtypes), viral escape from immune response and development of drug resistance. • Viral replication persists throughout infection. • Funda ...
89 Blood typ cont`d
... Glycoprotein (DAF or CD55, regulates complement fractions C3 and C5, attached to the membrane by GPI). ...
... Glycoprotein (DAF or CD55, regulates complement fractions C3 and C5, attached to the membrane by GPI). ...
Slide 1 - buechner
... Depends on actions of several types of T cells Antibodies are not produced, instead they directly attack foreign cells that carry antigens Other T cells release proteins to coordinate other actions of the immune response: T cells, B cells and macrophages Protects against parasites, bacteria, fungi, ...
... Depends on actions of several types of T cells Antibodies are not produced, instead they directly attack foreign cells that carry antigens Other T cells release proteins to coordinate other actions of the immune response: T cells, B cells and macrophages Protects against parasites, bacteria, fungi, ...
PowerPoint - Scranton Prep Biology
... against specific antigens When an antigen enters the body it activates only a small subset of lymphocytes that have complementary receptors. In clonal selection, the selected lymphocyte cells – multiply into clones of short-lived effector cells, specialized for defending against the antigen that ...
... against specific antigens When an antigen enters the body it activates only a small subset of lymphocytes that have complementary receptors. In clonal selection, the selected lymphocyte cells – multiply into clones of short-lived effector cells, specialized for defending against the antigen that ...
Slide 1 - buechner
... Depends on actions of several types of T cells Antibodies are not produced, instead they directly attack foreign cells that carry antigens Other T cells release proteins to coordinate other actions of the immune response: T cells, B cells and macrophages Protects against parasites, bacteria, fungi, ...
... Depends on actions of several types of T cells Antibodies are not produced, instead they directly attack foreign cells that carry antigens Other T cells release proteins to coordinate other actions of the immune response: T cells, B cells and macrophages Protects against parasites, bacteria, fungi, ...
Cancer immunotherapy
Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.