Word File - University of Georgia College of Veterinary Medicine
... supplementation of the maternal diet, and the desired effects on inflammatory and adaptive immunity observed (17). Further, the impact of omega-3 polyunsaturated fatty acids has even been demonstrated in neonatal piglets kept in a germ-free environment (18). Compared to unsupplemented piglets, the o ...
... supplementation of the maternal diet, and the desired effects on inflammatory and adaptive immunity observed (17). Further, the impact of omega-3 polyunsaturated fatty acids has even been demonstrated in neonatal piglets kept in a germ-free environment (18). Compared to unsupplemented piglets, the o ...
The Present Situation and Prospection of Gene
... gene which expression of tumor antigen into the virus, make its can not only express the tumor antigen but also express the virus antigen, activation of specific T cells, and then induce specific cellular immunity and humoral immunity. ...
... gene which expression of tumor antigen into the virus, make its can not only express the tumor antigen but also express the virus antigen, activation of specific T cells, and then induce specific cellular immunity and humoral immunity. ...
B cell tolerance
... This process activates an anergic B cell via a mechanism that does not involve the specific activation of the B cell by the binding of antigen to the immunoglobulin receptor but involves the nonspecific activation of the B cell by nonspecific multivalent antigens containing multiple repeating struct ...
... This process activates an anergic B cell via a mechanism that does not involve the specific activation of the B cell by the binding of antigen to the immunoglobulin receptor but involves the nonspecific activation of the B cell by nonspecific multivalent antigens containing multiple repeating struct ...
Intracellular Vesicular Traffic
... The basolateral and the apical domains of the plasma membrane communicate with separate early endosomal compartments ...
... The basolateral and the apical domains of the plasma membrane communicate with separate early endosomal compartments ...
Immunostimulating activity of maysin i
... and other polysaccharides isolated from natural materials (21). It has been reported that MAPKs play important roles in the activation of NF-κB and subsequent pro-inflammatory cytokine expression (22). Similarly, our results demonstrated that corn silk maysin significantly increase the levels of pho ...
... and other polysaccharides isolated from natural materials (21). It has been reported that MAPKs play important roles in the activation of NF-κB and subsequent pro-inflammatory cytokine expression (22). Similarly, our results demonstrated that corn silk maysin significantly increase the levels of pho ...
Le Mercier I et al, 2013
... Transplantable HER2/neu-expressing tumors escape immune response in WT mice while preserving HER2/neu expression. In order to characterize the potential role of pDC in primary breast tumor progression, we selected a clinically relevant murine mammary tumor model. HER-2/neu FVB/N transgenic mice expr ...
... Transplantable HER2/neu-expressing tumors escape immune response in WT mice while preserving HER2/neu expression. In order to characterize the potential role of pDC in primary breast tumor progression, we selected a clinically relevant murine mammary tumor model. HER-2/neu FVB/N transgenic mice expr ...
Antiinflammatory effects of apoptotic cells
... and removal of inflammatory cells. In a 1998 paper published in the JCI (7), we demonstrated that interaction of macrophages with apoptotic cells led to active suppression of their inflammatory mediator production (Figure 1A). This contributed to the current understanding of apoptotic cells as being ...
... and removal of inflammatory cells. In a 1998 paper published in the JCI (7), we demonstrated that interaction of macrophages with apoptotic cells led to active suppression of their inflammatory mediator production (Figure 1A). This contributed to the current understanding of apoptotic cells as being ...
Pattern recognition receptors
... receptors called pattern recognition receptors (PRRs) that are specialised in their recognition. These receptors are a key element of the innate immune system. They are mainly expressed by antigen presenting cells such as dendritic cells and macrophages, but they are also found in other immune and n ...
... receptors called pattern recognition receptors (PRRs) that are specialised in their recognition. These receptors are a key element of the innate immune system. They are mainly expressed by antigen presenting cells such as dendritic cells and macrophages, but they are also found in other immune and n ...
Immunology
... o Activation: requires presentation of membrane-bound Ag in association with MHC PLUS interaction of costimulatory molecules on APCs and T cells ...
... o Activation: requires presentation of membrane-bound Ag in association with MHC PLUS interaction of costimulatory molecules on APCs and T cells ...
Projects
... Project 5. Optimizing vaccination scheduler for sexually transmitted diseases, and in particular for human papillomavirus (HPV) 16 and 18 infection. Supervisors: Andrei Korobeinikov and Tomas Alarcon (CRM), and Mireia Diaz Sanchis (Unit of Infections and Cancer, Institut Català d' Oncologia, IDIBELL ...
... Project 5. Optimizing vaccination scheduler for sexually transmitted diseases, and in particular for human papillomavirus (HPV) 16 and 18 infection. Supervisors: Andrei Korobeinikov and Tomas Alarcon (CRM), and Mireia Diaz Sanchis (Unit of Infections and Cancer, Institut Català d' Oncologia, IDIBELL ...
Cell-mediated immunity to pseudorabies virus: cytolytic effector cells
... are important in the cytolysis of PRV-infected cells by LAK cells, we transfected L14 cells with plasmid pEVhis 14 containing one of the virus genes encoding gB, gC, gD or the immediate early (IE) protein, or with the empty control vector pEVhisl4. L14 cell lines stably expressing gB, gC, gD or the ...
... are important in the cytolysis of PRV-infected cells by LAK cells, we transfected L14 cells with plasmid pEVhis 14 containing one of the virus genes encoding gB, gC, gD or the immediate early (IE) protein, or with the empty control vector pEVhisl4. L14 cell lines stably expressing gB, gC, gD or the ...
Blood, Blood, and more Blood
... Every two seconds someone in the U.S. needs blood. More than 41,000 blood donations are needed every day. A total of 30 million blood components are transfused each year in the U.S. The average red blood cell transfusion is approximately 3 pints. The blood type most often requested by hospitals is T ...
... Every two seconds someone in the U.S. needs blood. More than 41,000 blood donations are needed every day. A total of 30 million blood components are transfused each year in the U.S. The average red blood cell transfusion is approximately 3 pints. The blood type most often requested by hospitals is T ...
Document
... receptors called pattern recognition receptors (PRRs) that are specialised in their recognition. These receptors are a key element of the innate immune system. They are mainly expressed by antigen presenting cells such as dendritic cells and macrophages, but they are also found in other immune and n ...
... receptors called pattern recognition receptors (PRRs) that are specialised in their recognition. These receptors are a key element of the innate immune system. They are mainly expressed by antigen presenting cells such as dendritic cells and macrophages, but they are also found in other immune and n ...
Protein Kinase R and dsRNAs, New Regulators of Mammalian Cell
... Discovery of new regulators of cell division The research team of the Center for RNA Research at IBS has succeeded in revealing that the dsRNAs and Protein Kinase R (PKR) regulate division of mammalian cells. This finding will provide important clues to understanding the process of tumor formation a ...
... Discovery of new regulators of cell division The research team of the Center for RNA Research at IBS has succeeded in revealing that the dsRNAs and Protein Kinase R (PKR) regulate division of mammalian cells. This finding will provide important clues to understanding the process of tumor formation a ...
About Chronic Myeloid Leukemia What Is Chronic Myeloid Leukemia?
... acute leukemia would only live a few months. Some types of acute leukemia respond well to treatment, and many patients can be cured. Other types of acute leukemia have a less favorable outlook. Lymphocytic leukemias (also known as lymphoid or lymphoblastic leukemia) start in the cells that become ly ...
... acute leukemia would only live a few months. Some types of acute leukemia respond well to treatment, and many patients can be cured. Other types of acute leukemia have a less favorable outlook. Lymphocytic leukemias (also known as lymphoid or lymphoblastic leukemia) start in the cells that become ly ...
Analysis of tumour infiltrating leukocytes in colon cancer
... Tumour immunity is a balance between immune mediators that promote tumor progression versus mediators that promote tumor rejection. Infiltrating lymphocytes in human colorectal cancer tissues are independent prognostic factors for a better survival and a high number of cytotoxic CD8+ T-cells have be ...
... Tumour immunity is a balance between immune mediators that promote tumor progression versus mediators that promote tumor rejection. Infiltrating lymphocytes in human colorectal cancer tissues are independent prognostic factors for a better survival and a high number of cytotoxic CD8+ T-cells have be ...
E-Mail Newsletter - Central Georgia Equine Services
... reduce vision if the immune system is not properly controlled. There are a set of checks and balances that minimize the chance of an unnecessary, overly aggressive immune response inside the eye. However, the immune system is out of balance in ERU; normal eye tissue is mistakenly attacked and damage ...
... reduce vision if the immune system is not properly controlled. There are a set of checks and balances that minimize the chance of an unnecessary, overly aggressive immune response inside the eye. However, the immune system is out of balance in ERU; normal eye tissue is mistakenly attacked and damage ...
e-Bug: Vaccinations
... inactivated by being killed or denatured by heat, radiation or other harmful conditions. The antigen is the same but the microorganism can no longer cause the infectious disease. Vaccines provide immunity by stimulating the immune system to produce antibodies to fight a particular infection or preve ...
... inactivated by being killed or denatured by heat, radiation or other harmful conditions. The antigen is the same but the microorganism can no longer cause the infectious disease. Vaccines provide immunity by stimulating the immune system to produce antibodies to fight a particular infection or preve ...
Two-zone tumor tolerance can arise from a simple
... (y, p) system using techniques suitable for planar systems, such as phase planes and nullclines. Information regarding the asymptotic behavior of u can be inferred from that of the (y, p) system. Suppose that we have determined that a solution (y(t), p(t)) tends to an equilibrium (ȳ, p̄) with p̄ 6= ...
... (y, p) system using techniques suitable for planar systems, such as phase planes and nullclines. Information regarding the asymptotic behavior of u can be inferred from that of the (y, p) system. Suppose that we have determined that a solution (y(t), p(t)) tends to an equilibrium (ȳ, p̄) with p̄ 6= ...
Cancer immunotherapy
Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.