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Immunity
Immunity

... antigens and produce antibodies. Clonal selection theory: During fetal development, B cells are produced which can bind with any potential antigen. Each B cell binds only one antigen. ...
By: Diana Marzulli, Sony Abraham and
By: Diana Marzulli, Sony Abraham and

... blood supply causes the redness, heat, and associated with inflammation.  This increased blood flow delivers antimicrobial proteins and other healing elements to the site.  The body may also initiate a systemic response in which a fever or increase in white blood cell count. The most severe of sys ...
The Lymphatic and System and the Immune System
The Lymphatic and System and the Immune System

... system overreacts to the presence of an antigen such as pollen. 2. An autoimmune disease is one in which the immune system attacks its own body cells. Ex. M.S. and Arthritis 3. Rejection of organ transplants (cells are foreign). 4. Cancer cells are naturally destroyed by the body; however, when the ...
How Immunity Evolved
How Immunity Evolved

... the Control of Adaptive Immunity • Antigen receptors expressed on lymphocytes have randomly generated specificities that cannot determine the origin or biological context of their ligands. • Signaling through an antigen receptor is insufficient on its own to induce the activation of lymphocytes or t ...
PowerPoint 簡報
PowerPoint 簡報

... Detect and eliminate cells that harbor intracellular pathogens. Ag-specific cells – CD4+ T cells, CD8+ T cells Ag-nonspecific cells – NK cells macrophages neutrophils eosinophils ...
Specific Immunity
Specific Immunity

... Specific Immunity: The immune response comes into play when pathogens make it past the first and second defenses. The Immune Response Makes Cells SPECIFIC for a Particular Pathogen’s Antigen Markers! G. The Immune Response and How It Works 26. This specific immune response attacks specific antigens ...
The humoral immune response defends against pathogens that are
The humoral immune response defends against pathogens that are

... Antibodies fight infections in three ways: they mark pathogens for destruction by phagocytic cells in a process known asopsonization, they coat key sites on pathogens necessary for infection, and they induce the complement cascade to occur against antibody-bound pathogens. Once the adaptive immune r ...
Chimeric Immune System
Chimeric Immune System

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... Viral DNA is created and inserts into cell’s DNA Infected cell divides with new DNA code Cell division creates raw protein material Raw infected material is packaged into an immature virus cell Leaves infected cell through “budding” New immature cell matures and then attacks another healthy cell New ...
anatomy and physiology answers
anatomy and physiology answers

... A) is based on recognition of antigens that are specific to different pathogens. B) is found only in vertebrate animals. C) depends on a newly infected animalʹs previous exposure to the same pathogen. D) is activated immediately upon infection. E) utilizes highly specific antigen receptors on B cell ...
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... their organelles, and turn the cell into a virus makingfactory. The cell will eventually burst, releasing thousands of viruses to infect new cells.  If you have ever heard of HIV, chicken pox, cold sores or the flu – then you have heard of viruses. *A virus will insert its DNA into the nucleus of t ...
The Immune System - SD43 Teacher Sites
The Immune System - SD43 Teacher Sites

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Immune System Cartoon Strip
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... Objective: Describe the role of the skin in providing non-specific defense against pathogens, Differentiate between specific and non-specific defenses, Explain the process in which antibodies oppose antigens in order to combat pathogens, Contrast T and B lymphocytes, Explain the role of vaccinations ...
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... macrophages and dendritic cells under normal states, and (2) in response to inflammation signals, monocytes can move quickly (approx. 8–12 hours) to sites of infection in the tissues and divide/differentiate into macrophages and dendritic cells to elicit an immune response. Half of them are stored i ...
ANTIBODIES - immunology.unideb.hu
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... Antibodies target virus infected cells, flagging them for the recognition by natural killer (NK) cells ...
Introduction To Immunology - Dow University of Health Sciences
Introduction To Immunology - Dow University of Health Sciences

... provide immediate protection and Vaccine to provide long term protection These preparations should be given at different sites in the body to prevent the antibodies from neutralizing the immunogen in the vaccine. This approach is used in the prevention of Tetanus, Rabies and Hepatitis B ...
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Adaptive immune system



The adaptive immune system, also known as the acquired immune or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogen growth. The adaptive immune system is one of the two main immunity strategies found in vertebrates (the other being the innate immune system). Adaptive immunity creates immunological memory after an initial response to a specific pathogen, leads to an enhanced response to subsequent encounters with that pathogen. This process of acquired immunity is the basis of vaccination. Like the innate system, the adaptive system includes both humoral immunity components and cell-mediated immunity components.Unlike the innate immune system, the adaptive immune system is highly specific to a specific pathogen. Adaptive immunity can also provide long-lasting protection: for example; someone who recovers from measles is now protected against measles for their lifetime but in other cases it does not provide lifetime protection: for example; chickenpox. The adaptive system response destroys invading pathogens and any toxic molecules they produce. Sometimes the adaptive system is unable to distinguish foreign molecules, the effects of this may be hayfever, asthma or any other allergies. Antigens are any substances that elicit the adaptive immune response. The cells that carry out the adaptive immune response are white blood cells known as lymphocytes. Two main broad classes—antibody responses and cell mediated immune response—are also carried by two different lymphocytes (B cells and T cells). In antibody responses, B cells are activated to secrete antibodies, which are proteins also known as immunoglobulins. Antibodies travel through the bloodstream and bind to the foreign antigen causing it to inactivate, which does not allow the antigen to bind to the host.In acquired immunity, pathogen-specific receptors are ""acquired"" during the lifetime of the organism (whereas in innate immunity pathogen-specific receptors are already encoded in the germline). The acquired response is called ""adaptive"" because it prepares the body's immune system for future challenges (though it can actually also be maladaptive when it results in autoimmunity).The system is highly adaptable because of somatic hypermutation (a process of accelerated somatic mutations), and V(D)J recombination (an irreversible genetic recombination of antigen receptor gene segments). This mechanism allows a small number of genes to generate a vast number of different antigen receptors, which are then uniquely expressed on each individual lymphocyte. Because the gene rearrangement leads to an irreversible change in the DNA of each cell, all progeny (offspring) of that cell inherit genes that encode the same receptor specificity, including the memory B cells and memory T cells that are the keys to long-lived specific immunity.A theoretical framework explaining the workings of the acquired immune system is provided by immune network theory. This theory, which builds on established concepts of clonal selection, is being applied in the search for an HIV vaccine.
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