Breast Cancer Cell–Derived GM-CSF Licenses
... EnVision Detection Systems Peroxidase/DAB (Dako) or GMCSF antibody and BDCA2 antibody (Dendritics). Bronchoalveolar adenocarcinoma tissue was kindly provided by Dr. Aurelie Fabre (Centre for Biological Resources, Bichat-Claude Bernard Hospital, Paris, France) and it was used as a positive control f ...
... EnVision Detection Systems Peroxidase/DAB (Dako) or GMCSF antibody and BDCA2 antibody (Dendritics). Bronchoalveolar adenocarcinoma tissue was kindly provided by Dr. Aurelie Fabre (Centre for Biological Resources, Bichat-Claude Bernard Hospital, Paris, France) and it was used as a positive control f ...
papillomaviruses and cancer: from basic studies to
... cells can impair the function of viral oncoproteins is still indirect and, so far, exists only for the E6 oncoprotein in cells that have been immortalized by E6 alone55. In cell lines that have been transfected with E6 DNA, the CDKN2A gene — which encodes INK4A — is commonly inactivated by methylati ...
... cells can impair the function of viral oncoproteins is still indirect and, so far, exists only for the E6 oncoprotein in cells that have been immortalized by E6 alone55. In cell lines that have been transfected with E6 DNA, the CDKN2A gene — which encodes INK4A — is commonly inactivated by methylati ...
ECronicon
... Trastuzumab: A recombinant humanized monoclonal antibody directed against human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpr ...
... Trastuzumab: A recombinant humanized monoclonal antibody directed against human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpr ...
Infection T Cell Response during Chronic Viral +CD8 Exhaustion
... protect against a primary infection with a viral variant mutated in the critical epitope. However, single-epitope-vaccinated individuals infected with a wild-type virus might subsequently be more susceptible to viral variants than unvaccinated, wild-type virus-infected individuals due to a more narr ...
... protect against a primary infection with a viral variant mutated in the critical epitope. However, single-epitope-vaccinated individuals infected with a wild-type virus might subsequently be more susceptible to viral variants than unvaccinated, wild-type virus-infected individuals due to a more narr ...
The challenges of modelling antibody repertoire dynamics in HIV
... Neutralizing antibodies specific to the transmitted HIV strain, called autologous antibodies, eventually arise, but are typically not detected until months after infection, with some patients taking more than a year [2,16,20,21]. The epitopes targeted by these neutralizing antibodies tend to be in v ...
... Neutralizing antibodies specific to the transmitted HIV strain, called autologous antibodies, eventually arise, but are typically not detected until months after infection, with some patients taking more than a year [2,16,20,21]. The epitopes targeted by these neutralizing antibodies tend to be in v ...
Basophils: new players in the cytokine network
... [20], in spite of the fact that this growth factor promotes their in vitro differentiation from normal bone marrow cells [21, 22], mediates in vivo basophilia after injection [23], maintains their survival through a Pim1-dependent mechanism [24], and is required for their expansion during parasitosi ...
... [20], in spite of the fact that this growth factor promotes their in vitro differentiation from normal bone marrow cells [21, 22], mediates in vivo basophilia after injection [23], maintains their survival through a Pim1-dependent mechanism [24], and is required for their expansion during parasitosi ...
FULL TEXT - Journal of Pre-Clinical and Clinical Research
... of divergent results, no final statement on the association between childhood disease and cancer may be made. However, taking into consideration our results and published data we must stress that febrile contagious illnesses during early life are probably not sufficient to protect against cancer becaus ...
... of divergent results, no final statement on the association between childhood disease and cancer may be made. However, taking into consideration our results and published data we must stress that febrile contagious illnesses during early life are probably not sufficient to protect against cancer becaus ...
Strengthening the Immune System
... responses designed to free our systems of potentially dangerous substances: viruses, bacteria, parasites, chemical and environmental poisons, free radicals and industrial pollutants. In its simplest form, the immune system is a system of barriers to pathogens or irritations, detection of invaders an ...
... responses designed to free our systems of potentially dangerous substances: viruses, bacteria, parasites, chemical and environmental poisons, free radicals and industrial pollutants. In its simplest form, the immune system is a system of barriers to pathogens or irritations, detection of invaders an ...
Fish and Shellfish Immunology
... The Gram-negative bacteria Aeromonas hydrophila is a heterogeneous organism that causes the disease known as motile aeromonad septicaemia, which is responsible for serious economic loss in seabream culture due to bacterial infections. However, the immune mechanisms involved in this disease in fish ar ...
... The Gram-negative bacteria Aeromonas hydrophila is a heterogeneous organism that causes the disease known as motile aeromonad septicaemia, which is responsible for serious economic loss in seabream culture due to bacterial infections. However, the immune mechanisms involved in this disease in fish ar ...
CC Chemokine Receptor 4 Contributes to Innate NK and Chronic
... CCR4 is reportedly expressed by platelets, natural killer (NK) cells, macrophages, basophils, and dendritic cells (DCs).1 Regarding T-cell subsets, naïve T cells do not express CCR4, suggesting a role in memory or effector T-cell function. Initially, CCR4 was purported to be a marker of Th2 cells, b ...
... CCR4 is reportedly expressed by platelets, natural killer (NK) cells, macrophages, basophils, and dendritic cells (DCs).1 Regarding T-cell subsets, naïve T cells do not express CCR4, suggesting a role in memory or effector T-cell function. Initially, CCR4 was purported to be a marker of Th2 cells, b ...
Cytokine production of RSV/PHA-stimulated tonsillar mononuclear S. Ichinohe , I.R. Hussain
... Cytokine production of RSV/PHA-stimulated tonsillar mononuclear cells: influences of age and atopy. S. Ichinohe, I.R. Hussain, S.L. Johnston. #ERS Journals Ltd 2003. ABSTRACT: Links between immune responses to respiratory syncytial virus (RSV), age and atopic sensitisation are poorly understood. Thi ...
... Cytokine production of RSV/PHA-stimulated tonsillar mononuclear cells: influences of age and atopy. S. Ichinohe, I.R. Hussain, S.L. Johnston. #ERS Journals Ltd 2003. ABSTRACT: Links between immune responses to respiratory syncytial virus (RSV), age and atopic sensitisation are poorly understood. Thi ...
Explaining Therapies – Annemieke Aartsma-Rus
... • How does drug development work • What genetic approaches are in development to replace dystrophin? ...
... • How does drug development work • What genetic approaches are in development to replace dystrophin? ...
Immunology Program Graduates
... Thesis Advisor: Dr. Angus Thomson Ethanol Exposure and Dendritic Cell Function Lazar Vujanovic, Ph.D., 2006 Thesis Advisor: Dr. Walter Storkus Promoting Type-1 CD4+ T Cell Immune Responses against Tumor-associated Antigen MAGE-A6 Pamela Beatty, Ph.D., 2006 Thesis Advisosr: Dr. Olivera Finn MUC1 in t ...
... Thesis Advisor: Dr. Angus Thomson Ethanol Exposure and Dendritic Cell Function Lazar Vujanovic, Ph.D., 2006 Thesis Advisor: Dr. Walter Storkus Promoting Type-1 CD4+ T Cell Immune Responses against Tumor-associated Antigen MAGE-A6 Pamela Beatty, Ph.D., 2006 Thesis Advisosr: Dr. Olivera Finn MUC1 in t ...
