The influence of sex and gender on immunity, infection and
... immune response. Gender refers to the differences between males and females regulated by cultural and social factors that, involving all areas of human life, consequently affect the different steps of the immune response. Exposure to various types of antigens, access to health promotion programs and ...
... immune response. Gender refers to the differences between males and females regulated by cultural and social factors that, involving all areas of human life, consequently affect the different steps of the immune response. Exposure to various types of antigens, access to health promotion programs and ...
Licentiate-thesis from the Department of Immunology, Wenner-Gren Institute, Stockholm University, Sweden
... lymphocytes that are primed in the PP migrate to the MLN for further differentiation, then enter the bloodstream and further accumulate in the mucosa. As with B lymphocytes, T lymphocytes up regulate the adhesion molecules CCR9 and α4β7 which facilitates the migration to the gut mucosa. Both CD4+ a ...
... lymphocytes that are primed in the PP migrate to the MLN for further differentiation, then enter the bloodstream and further accumulate in the mucosa. As with B lymphocytes, T lymphocytes up regulate the adhesion molecules CCR9 and α4β7 which facilitates the migration to the gut mucosa. Both CD4+ a ...
Induction of protective immunity to Cryptococcal infection in mice by
... component of the cryptococcal capsule, peptide mimotopes of GXM, complex mixtures of cell surface mannoproteins, and melanin (13–16). Moreover, fungal -glucan particles have been exploited as an adjuvant and, also, as a vaccine delivery system due to their ability to stimulate dendritic cells to se ...
... component of the cryptococcal capsule, peptide mimotopes of GXM, complex mixtures of cell surface mannoproteins, and melanin (13–16). Moreover, fungal -glucan particles have been exploited as an adjuvant and, also, as a vaccine delivery system due to their ability to stimulate dendritic cells to se ...
by a Novel Mass Spectrometric Technique Cysteinylated Cysteine
... Mass spectrometric identification of the A1-HY epitope HLA-A*0101-associated peptides were purified from male Rp cells and fractionated by reverse phase HPLC using HFBA as the ion-pairing reagent. Epitope reconstitution was performed by adding aliquots of these fractions to the HLA-A*01011 female ta ...
... Mass spectrometric identification of the A1-HY epitope HLA-A*0101-associated peptides were purified from male Rp cells and fractionated by reverse phase HPLC using HFBA as the ion-pairing reagent. Epitope reconstitution was performed by adding aliquots of these fractions to the HLA-A*01011 female ta ...
Lymphatic Vessels, Inflammation, and Immunity
... (21). B cells secrete (auto)antibodies that form immune complexes with complement proteins—these accumulate in skin and influence resident and recruited myeloid cells’ activation and function (20). Tumor-infi ltrating leukocytes play an important role in regulating angiogenic responses, which, in turn ...
... (21). B cells secrete (auto)antibodies that form immune complexes with complement proteins—these accumulate in skin and influence resident and recruited myeloid cells’ activation and function (20). Tumor-infi ltrating leukocytes play an important role in regulating angiogenic responses, which, in turn ...
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... Hemolytic anemias – result from shortened RBC survival due to increased rate of destruction Pathogenesis – anemia occurs when rate of destruction exceeds ability of marrow to replace RBCs o Bone marrow – can increase rate of production 6-8 times baseline rate o Absence of anemia – doesn’t rule o ...
... Hemolytic anemias – result from shortened RBC survival due to increased rate of destruction Pathogenesis – anemia occurs when rate of destruction exceeds ability of marrow to replace RBCs o Bone marrow – can increase rate of production 6-8 times baseline rate o Absence of anemia – doesn’t rule o ...
International Society for Biological Therapy of Cancer 24th Annual
... strongly inhibited the growth of B16 melanoma and MC38 colon cancers significantly prolonged the survival of tumor-bearing animals without any treatment-related adverse toxicities. The in vivo antitumor activity of DC101-CAR modified T cells directly correlated with number-infused T cells. The presenc ...
... strongly inhibited the growth of B16 melanoma and MC38 colon cancers significantly prolonged the survival of tumor-bearing animals without any treatment-related adverse toxicities. The in vivo antitumor activity of DC101-CAR modified T cells directly correlated with number-infused T cells. The presenc ...
Induction of Th2 type immunity in a mouse system
... peptide plus splenic CD11c⫹ dendritic cells in the absence of exogenous cytokines for 3 days. About 40% of the activated 5C.C7 CD4 T cells produced IFN␥ and no IL-4 upon restimulation (Figure 2A). Addition of 2 ⫻ 104 FACS-sorted basophils in the culture shifted T-cell differentiation patterns. Thus, ...
... peptide plus splenic CD11c⫹ dendritic cells in the absence of exogenous cytokines for 3 days. About 40% of the activated 5C.C7 CD4 T cells produced IFN␥ and no IL-4 upon restimulation (Figure 2A). Addition of 2 ⫻ 104 FACS-sorted basophils in the culture shifted T-cell differentiation patterns. Thus, ...
Wheat Amylase Trypsin Inhibitors as Nutritional Activators of Innate
... monocytes, DCs, and polymorphonuclear leukocytes that by means of their pattern-recognition receptors, such as TLRs, induce the release of proinflammatory cytokines and chemokines, resulting in recruitment and activation of additional inflammatory cells (Medzhitov, 2007). Thus, peptides p31-43 or p3 ...
... monocytes, DCs, and polymorphonuclear leukocytes that by means of their pattern-recognition receptors, such as TLRs, induce the release of proinflammatory cytokines and chemokines, resulting in recruitment and activation of additional inflammatory cells (Medzhitov, 2007). Thus, peptides p31-43 or p3 ...
CELLS, ORGANS & THE HUMAN BODY SYSTEMS TEACHER
... The books are self-explanatory as to what lesson they would be best used. Scheduling: Body Systems Unit can take from 10 – 16 weeks depending on the maturity of the students and the time allotted for science lessons. There are 8 “Lessons” with ~4 activities within each that include lab activities fo ...
... The books are self-explanatory as to what lesson they would be best used. Scheduling: Body Systems Unit can take from 10 – 16 weeks depending on the maturity of the students and the time allotted for science lessons. There are 8 “Lessons” with ~4 activities within each that include lab activities fo ...
Lymphatic System - El Camino College
... Right Lymphatic duct – collects lymph from right arm, right side of head, neck and thorax. When absent, the lymphatic trunks directly open into veins of the neck. Thoracic Duct – collects lymph from rest of the body. It arises inferiorly as an extended sac – Cisterna Chyli, in front of 1st and 2nd l ...
... Right Lymphatic duct – collects lymph from right arm, right side of head, neck and thorax. When absent, the lymphatic trunks directly open into veins of the neck. Thoracic Duct – collects lymph from rest of the body. It arises inferiorly as an extended sac – Cisterna Chyli, in front of 1st and 2nd l ...
Full-Text PDF
... 2. Differentiation of B-Cells and Generation of IgA Induced by Gut Microbiota The process of intestinal colonization starts at birth, when neonates are exposed to microorganisms from the maternal birth canal and the external environment. Bacterial colonization of the gut is a trigger for the inducti ...
... 2. Differentiation of B-Cells and Generation of IgA Induced by Gut Microbiota The process of intestinal colonization starts at birth, when neonates are exposed to microorganisms from the maternal birth canal and the external environment. Bacterial colonization of the gut is a trigger for the inducti ...
Article (Author postprint)
... cell type specificity of the reactions is the foundation of immunological research, and capturing this specificity is of paramount importance when using pathway-based analyses to decipher complex immunological datasets. Here, we present DC-ATLAS, a novel and versatile resource for the interpretation ...
... cell type specificity of the reactions is the foundation of immunological research, and capturing this specificity is of paramount importance when using pathway-based analyses to decipher complex immunological datasets. Here, we present DC-ATLAS, a novel and versatile resource for the interpretation ...
Photochemotherapy induces the apoptosis of - HAL
... immunomodulation and effectors identified in these studies could be different than those involved in human ECP. Among the treated cells, monocytes are a major group since they represent up to 30% of PBMC(12). It is well known that monocytes play an important role in adaptive immunity as they modulat ...
... immunomodulation and effectors identified in these studies could be different than those involved in human ECP. Among the treated cells, monocytes are a major group since they represent up to 30% of PBMC(12). It is well known that monocytes play an important role in adaptive immunity as they modulat ...
Effects of deviating the Th2-response in murine mercury
... diseases. In many Th1-dependent autoimmune models, treatment with recombinant interleukin-12 (rIL12) accelerates the autoimmune response. Mercury-induced autoimmunity (HgIA) in mice is an H-2 regulated condition with antinucleolar antibodies targeting fibrillarin (ANoA), systemic immunecomplex (IC) ...
... diseases. In many Th1-dependent autoimmune models, treatment with recombinant interleukin-12 (rIL12) accelerates the autoimmune response. Mercury-induced autoimmunity (HgIA) in mice is an H-2 regulated condition with antinucleolar antibodies targeting fibrillarin (ANoA), systemic immunecomplex (IC) ...
SUMMARY AND EXPLANATION OF THE TEST
... normal epithelial cell lines.8,9 Using in situ hybridization methods in tumor specimens, hCFHrp was shown to be produced by cancer cells and macrophages but not by normal epithelia . hCFH plays a key inhibitory role in the control of the alternative complement pathway that functions to lyse cells re ...
... normal epithelial cell lines.8,9 Using in situ hybridization methods in tumor specimens, hCFHrp was shown to be produced by cancer cells and macrophages but not by normal epithelia . hCFH plays a key inhibitory role in the control of the alternative complement pathway that functions to lyse cells re ...
Giuliana Magri Characterization of natural killer cell response to human cytomegalovirus
... and recognition of transformed or infected cells, as well as via antibody dependent cellular cytotoxicity (ADCC) through engagement of FcγRIII receptor (CD16)15. The main cytotoxic pathway involves perforin and granzymes that are stored in granules inside NK cells and get released by exocytosis upon ...
... and recognition of transformed or infected cells, as well as via antibody dependent cellular cytotoxicity (ADCC) through engagement of FcγRIII receptor (CD16)15. The main cytotoxic pathway involves perforin and granzymes that are stored in granules inside NK cells and get released by exocytosis upon ...
Introduction to Immunoassays
... of laboratory tests, such as colorimetric tests, because they use antibody:antigen complexes to generate a signal that can be measured. • In contrast, most routine clinical chemistry tests utilize chemical reactions between the reagent (a solution of chemicals or other agents) and patient sample to ...
... of laboratory tests, such as colorimetric tests, because they use antibody:antigen complexes to generate a signal that can be measured. • In contrast, most routine clinical chemistry tests utilize chemical reactions between the reagent (a solution of chemicals or other agents) and patient sample to ...
HIC1 links retinoic acid signalling to group 3 innate
... Burrows et al. 5 2016), with one study showing a concomitant increase in ILC2 numbers and enhanced type 2 immunity within the intestine (Spencer et al., 2014). In addition, intestinal DC differentiation is influenced by atRA as mice raised on a VAD diet display reduced numbers of CD103+ CD11b+ DCs ( ...
... Burrows et al. 5 2016), with one study showing a concomitant increase in ILC2 numbers and enhanced type 2 immunity within the intestine (Spencer et al., 2014). In addition, intestinal DC differentiation is influenced by atRA as mice raised on a VAD diet display reduced numbers of CD103+ CD11b+ DCs ( ...
dependent regulation of intestinal immunity and homeostasis
... Burrows et al. 5 2016), with one study showing a concomitant increase in ILC2 numbers and enhanced type 2 immunity within the intestine (Spencer et al., 2014). In addition, intestinal DC differentiation is influenced by atRA as mice raised on a VAD diet display reduced numbers of CD103+ CD11b+ DCs ( ...
... Burrows et al. 5 2016), with one study showing a concomitant increase in ILC2 numbers and enhanced type 2 immunity within the intestine (Spencer et al., 2014). In addition, intestinal DC differentiation is influenced by atRA as mice raised on a VAD diet display reduced numbers of CD103+ CD11b+ DCs ( ...
BIO INSPIRED COMPUTING In
... perspective. In addition to its potential applications, such as DNA computation, nanofabrication, storage devices, sensing, and health care, biocomputation also has implications for basic scientific research. It can provide biologists, for example, with an IT-oriented paradigm for looking at how cel ...
... perspective. In addition to its potential applications, such as DNA computation, nanofabrication, storage devices, sensing, and health care, biocomputation also has implications for basic scientific research. It can provide biologists, for example, with an IT-oriented paradigm for looking at how cel ...
Current Progress in Non-Invasive Imaging of Beta Cell Mass of the
... by T and B lymphocytes, monocytes/macrophages, and natural killer cells [18]. Recently, studies have also suggested that there may be significant residual pancreatic insulin secretory capacity at diagnosis. These studies are based on indirect evidence and need clarification [19]. Undoubtedly, direct ...
... by T and B lymphocytes, monocytes/macrophages, and natural killer cells [18]. Recently, studies have also suggested that there may be significant residual pancreatic insulin secretory capacity at diagnosis. These studies are based on indirect evidence and need clarification [19]. Undoubtedly, direct ...