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... at least two different kinds of complement receptors that aid in phagocytosis. C3b, a cleavage product formed during activation is the major player. Antigen coated with C3b binds to cells bearing complement receptors and if the cell is a phagocyte the antigen will be phagocytosed. ...
Cytopenias developing after solid organ transplantation
Cytopenias developing after solid organ transplantation

...  Leukopenia by marrow suppression  Sirolimus  Anemia esp in renal transplant (iron hemostasis, direct anti proliferative effect, IL 10 activation)  Azathioprine  Anemia/pancytopenia  Alemtuzumab: reports of PRCA and immune hemolysis  Pure red-cell aplasia : MMF, tacrolimus, azothioprine and A ...
PowerPoint Presentation - I. Introduction to class
PowerPoint Presentation - I. Introduction to class

... surface of host cells then leads to:  Opsonization of the host cell.  Activation of the classical complement pathway causing MAC lysis ( membrane attack complex ) of the cells.  ADCC (Antibody-Dependent CellMediated Cytotoxicity ) destruction of the host cells. ...
Document
Document

... barriers, they must face your body’s fighters in hand-tohand combat. • Invaders are winning= you are sick • Your body is winning= you are healthy ...
Handout
Handout

... those with intracellular bacteria can also function as antigen presenting cells – ‘showing’ antigen to T cells (see fig 17.12) ...
Power Point
Power Point

... The complement system (Abbr. C): • A group of proteins present in the plasma of all individuals. Part of the innate immune system. • A major biological effector system of both the innate and the adaptive immune responses. • The C components are present in the plasma in an inactive state. • Upon acti ...
Immunology 1
Immunology 1

... connection of components consisting of two main branches, a vast number of different kinds of cells carrying out different functions, interacting via an equally vast number and different kinds of noncellular, small molecules, etc. The immune system, in a nutshell, can carry out this function by two ...
Disseminated ldiopathic Myositis in Young Marshall Farms Ferrets
Disseminated ldiopathic Myositis in Young Marshall Farms Ferrets

... cells). Another form of immuneDisseminated Idiopathic Myositis mediated anemia can occur if the is a descriptive term for what the immune system damages the bone "disseminated"means diseasedoes: "idiopathic" means marrow, but the anemia in those widespread; (no new "of unknown origin or cause"; and ...
Lymphatic System
Lymphatic System

... Usually less than 2.5 cm long Bean shaped FUNCTIONS:  Filters potentially harmful particles ...
Executive Summary
Executive Summary

Module 6 Immunology
Module 6 Immunology

... Major immunoglobulin of defense Part of secondary immune response This is the only antibody that can cross through the placenta Causes agglutination of pathogens Coats surface of foreign bodies for ingestion by phagocytes Activates complement system ...
Transplantation Immunology October 1st, 2003 HHSC 401 Outline
Transplantation Immunology October 1st, 2003 HHSC 401 Outline

... (Prevent hyperacute rejection in solid organs) (Prevent transfusion reaction in BM/PBSC) ...
Aankondiging_Immuno_7nov
Aankondiging_Immuno_7nov

1 CAR-‐T Cell Therapy – Fact Sheet
1 CAR-‐T Cell Therapy – Fact Sheet

... safely  and  successfully.  The  genetic  modification  step  involves  introducing  into  the  T  cells  an   extra  gene  using  a  vector  that  carries  instructions  to  recognize  tumour  cells.  As  a  result,  the  T   cell  bec ...
Detailed Outline and Resources for Lesson Planning
Detailed Outline and Resources for Lesson Planning

...  Helper T cells – release cytokines that promote T cell growth and plasma cell production of antibodies  Suppressor T cells – shut down immune response when no longer needed  Fig 12-7 summarizes immune responses ...
body defenses - Mr. Van Arsdale
body defenses - Mr. Van Arsdale

... ______ Cells held in reserve; differentiate to form plasma cells with second exposure to antigen ______ Responsible for cell-mediated immunity; track down and attack bacteria, fungi, protozoa and foreign tissues that contain targeted antigen ______ Release cytokines that coordinate specific & nonspe ...
Transplantation Immunology
Transplantation Immunology

... 3- detection of preformed Abs against donor cells in the serum of the recipient ...
3.6 Immune System
3.6 Immune System

... down  along  with  any  human  cells  damaged  by the pathogen.  Fragments  of  dead  pathogen  and  white  blood  cells  form  _________________​ ...
Immune Work-Up for the General Pediatrician
Immune Work-Up for the General Pediatrician

... seen after 6 months when maternal antibodies lost  Growth usually normal unless patient with chronic infections ...
Human Defence System - Mr Murphy`s Science Blog
Human Defence System - Mr Murphy`s Science Blog

... tissue, e.g. spleen and lymph nodes  There are many millions of different B-cells  Each B-cell is adapted to recognise only one specific antigen, which is usually present on the surface of a macrophage  Each B-cell produces only one type of antibody  When a B-cell comes into contact with the ant ...
Wk13-P.aerug.
Wk13-P.aerug.

... • Capable of causing disease in plants, animals and immunocompromised humans • Has the ability to colonize a wide variety of tissues in the body and is capable of causing extensive tissue damage • This ability to cause damage is a direct result of its quorum sensing ...
Lecture 5 T Cell-Mediated Immunity
Lecture 5 T Cell-Mediated Immunity

... microbial preparation (eg. heat-killed extract of Mycobacterium tuberculosis) aqueous phase containing antigen ...
PowerPoint 演示文稿
PowerPoint 演示文稿

... 4. Symptom control diuretics and anti-hypertension therapy ...
31.4 Immunity and Technology KEY CONCEPT help keep a person healthy.
31.4 Immunity and Technology KEY CONCEPT help keep a person healthy.

... – examples include vinegar and soap • Antibiotics kill pathogens inside the body. – target one specific bacterium or fungus – not effective against viruses ...
Master Answers for the Autoimmune Disease Small group Master
Master Answers for the Autoimmune Disease Small group Master

... preferentially destroyed by virus and tolerance to beta cells is lost. Yet another possibility is that Beta cells are destroyed as “collateral damage” during a TIMI response in neighboring pancreatic tissue Yet another possibility is that the patient has a partial autoimmune regulator (Aire) defect ...
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Immunosuppressive drug

For a list of immunosuppressive drugs, see the transplant rejection page.Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act non-selectively, resulting in increased susceptibility to infections and decreased cancer immunosurveillance. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs.
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