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BIOLOGY PRESENTATION
BIOLOGY PRESENTATION

... found in human it’s called HLA-C (human leukocyte antigen) it’s the human MHC and HLA C is the less polymorphic of all the HLA just to keep the barrier as neutral as possible. Immunosuppresion is a way of suppressing the immune response to protect the fetus against rejection. Two scientists called M ...
Why an immune system? - Fairfield Public Schools
Why an immune system? - Fairfield Public Schools

... • When a local response is not enough • system-wide response to infection • activated macrophages release interleukin-1 • triggers hypothalamus in brain to readjust body thermostat to raise body temperature ...
Infections in the compromised host
Infections in the compromised host

Isotype switching Diversification of Igs after B cells encounter antigens
Isotype switching Diversification of Igs after B cells encounter antigens

...  Constant regions of IgM and IgA antibodies contain a region essential for polymerization.  J chain–small peptide that links the polymerization region of Ig molecules to form a polymer.  J chains allow IgA to form dimers and IgM to form pentamers. ...
Calcium-independent calcineurin regulation
Calcium-independent calcineurin regulation

... there is compelling evidence that aberrant expression of Fas ligand precipitates the TH1 defect in Csp1-deficient lymphocytes. Finally, the authors propose a hierarchical model for Csp1 alteration of calcineurin dependent transcription. The activation thresholds of several genes were measured in ter ...
Study Guide - Communicable Diseases, Ch
Study Guide - Communicable Diseases, Ch

... your body from disease, the adaptive immune system mounts specific attacks against particular types of pathogens.) 1) Lymphocytes - A type of white blood cell that fights pathogens. a) B Cells—Turn into plasma cells, which produce antibodies. (Antibodies are proteins that destroy or neutralize invad ...
HUMAN CELL TYPES
HUMAN CELL TYPES

... particular pathogens. Recognition occurs by the body cell usually having some of the pathogen’s antigens on their surface. Body cells are destroyed when their membrane is punctured. 5. Suppressor T cells – responsible for shutting down the immune response after the pathogen has been cleared from the ...
Chapter 50
Chapter 50

... Copyright © 2008 Lippincott Williams & Wilkins. ...
Biochemistry of the immune system
Biochemistry of the immune system

... • Interleukins - presumed targets are principally leukocytes. • Lymphokines - produced by activated T lymphocytes direct the immune system response by signaling between its cells ...
Mediators of inflammation
Mediators of inflammation

... Activation of leukocytes and other cellsstimulates microbicidal activity of macrophages by inducing production of NO. IL1 activates fibroblasts to synthesize collagen and stimulates proliferation of synovial and other mesenchymal cells. stimulates TH17 responses- induce acute inflmmation ...
Lecture 1 Food Allergy Immunology and Symptoms
Lecture 1 Food Allergy Immunology and Symptoms

... » Interferon-gamma (IFN-) » Interleukin-2 (IL-2) » Tumor necrosis factor alpha (TNF) » IL-12 • Th2 subclass produces: » Interleukin-4 (IL-4) » Interleukin-5 (IL-5) » Interleukin-6 (IL-6) » Interleukin-8 (IL-8) » Interleukin-10 (IL-10) » Interleukin-13 (IL-13) ...
Answers / Solutions
Answers / Solutions

... 1. Acid base balance : It is the regulation of H+ ions in the body fluids. Any change in the pH value can cause alterations in the rate of chemical reactions. This can be maintained by buffering systems within the body. 2. Ionic balance : It is the regulation of ions like H, Na, Cl, K, Mg, HCO3 whic ...
Immune responses to bacteria
Immune responses to bacteria

... survive inside cells. Macrophages are a common targets for intracellular bacteria (e.g. Salmonella spp.) that live inside cell compartments. These bacteria cannot be detected by complement or antibody but, instead, are eliminated using a cell-mediated response. Infected macrophages present bacterial ...
Immune Responses to Bacteria
Immune Responses to Bacteria

... survive inside cells. Macrophages are a common targets for intracellular bacteria (e.g. Salmonella spp.) that live inside cell compartments. These bacteria cannot be detected by complement or antibody but, instead, are eliminated using a cell-mediated response. Infected macrophages present bacterial ...
McDermott
McDermott

... provided for topics we will cover and consist of a series of questions pertaining to the topic. As we finish a topic, answers to the questions posed on the Objective Sheets will be due the next class period and will be worth up to 1 extra credit point each (15-20/semester). Extra credit points will ...
幻灯片 1
幻灯片 1

... TI-1 antigen: also named B cell mitogen 1. Contains B cell mitogen and repeated B epitopes 2. Can induce immature and mature B cell-mediate immune response 3. In high concentrations, can induce polyclonal B-cell activation 4. In lower concentrations, only the BCR-binding TI-1 antigens can activate ...
The Lymphatic System and Body Defenses
The Lymphatic System and Body Defenses

... Functions of Cells and Molecules Involved in Immunity Humoral (Antibody-Mediated) Immune Response  B lymphocytes with specific receptors bind to a specific antigen  The binding event activates the lymphocyte to undergo clonal selection  A large number of clones are produced (primary humoral respo ...
prevent - Model High School
prevent - Model High School

... genetic material, causing new strains to develop in a single generation. ...
Innate immunity 2015-16
Innate immunity 2015-16

... Innate immunity: always present (ready to attack); many pathogenic microbes have evolved to resist innate immunity Adaptive immunity: stimulated by exposure to microbe; more potent ! ...
Answer Key- Chapter 24 - Scarsdale Public Schools
Answer Key- Chapter 24 - Scarsdale Public Schools

... 15. Refer to Figure 24.8B on page 493 of your textbook. How many days did it take for antibody concentration to peak after initial exposure to antigen X? How many days did it take for antibody concentration to peak after exposure to antigen X the second time? How many days did it take for the seco ...
DEFINITIONS - Microbiology Book
DEFINITIONS - Microbiology Book

... Contribution of the Biological System • Genetics – Species – Individual • Responders vs Non-responders ...
Immunology in Rheumatic Diseases
Immunology in Rheumatic Diseases

... Unlike the other cells, TH cells only recognize antigen that is properly presented with MHC by other cells These specialized cells are called antigen presenting cells They include macrophages, B cells, fibroblasts & dendritic cells ...
Cancer immunotherapy comes of age
Cancer immunotherapy comes of age

... Kaufman. Around 20% of all cancers respond to this type of certain T cells to identify the tumor as nonself. treatment, he estimates. Those tend to be the people who already T cells use T-cell receptors (TCRs) to identify antigens. have cancer-targeted T cells waiting in their tumors before Research ...
Missing genetic link found in a challenging immune disease
Missing genetic link found in a challenging immune disease

Powerpoint
Powerpoint

... – cytokines & other mediators produced by macrophages & epithelial cells ...
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Immunosuppressive drug

For a list of immunosuppressive drugs, see the transplant rejection page.Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act non-selectively, resulting in increased susceptibility to infections and decreased cancer immunosurveillance. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs.
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