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Pathophysiology of inflammation
Pathophysiology of inflammation

Chapter 21 - Immune System
Chapter 21 - Immune System

... – B-cells and T-cells recognize foreign molecules or antigens (Ag) • Memory – they remember which antigens have entered the body ...
Virus Notes - ScienceCo
Virus Notes - ScienceCo

“The Immune System”
“The Immune System”

... • Killer T cells destroy our cancerous cells. • Immune system fails to locate and remove cancerous cell, & it multiplies to form a ...
The immune system may be viewed as one aspect of the lymphatic
The immune system may be viewed as one aspect of the lymphatic

... groups: IgM, IgA, IgD, IgG, IgE (the acronym MADGE may help to remember them). Further, antigens that provoke an allergic response are called allergens. For unknown reasons, in some people IgE antibodies (produced in response to past exposure to allergens on pollen, mold spores, animal dander, etc.) ...
Backup of 43
Backup of 43

... A. The skin and mucous membranes (Barrier defenses) ...
ABSTRACT  THESIS: STUDENT:
ABSTRACT THESIS: STUDENT:

... Oral tolerance is an immunologic hyporesponsiveness to an orally administered antigen. Probiotics (beneficial intestinal bacteria), T regulatory cells (Tregs), and dendritic cells (DCs) are all essential for generating tolerance and suppressing immune responses toward harmless antigens. Antibiotics ...
lung cancer 3
lung cancer 3

... The effector cell types implicated in the tumour rejection process are cytotoxic T lymphocytes (CTLs), Ab-dependent killer cells, natural killer (NK) cells and macrophages, all of which act either alone or together with other cell types. ...
Freeman 1e: How we got there
Freeman 1e: How we got there

... intrinsic properties of immunogens. • Molecular size is an important component of immunogenicity. For example, low-molecularweight compounds called haptens cannot induce an immune response but can bind to antibodies. Because haptens are bound by antibodies, they are antigens even though they are not ...
Vaccination - WordPress.com
Vaccination - WordPress.com

Immune Checkpoint Inhibitors
Immune Checkpoint Inhibitors

Hypersensitivity-contact dermatitis
Hypersensitivity-contact dermatitis

... •Hypersensitivity reaction in which antibody on mast cells quickly reacts with an antigen. •Mast cells release histamine & other mediators that lead to edema. •Local allergies- confined to skin and mucous membranes ...
CHAPTER 42 Pathogenesis of Fungal Infections
CHAPTER 42 Pathogenesis of Fungal Infections

... A. Innate Immunity 1. Normal persons have a high level of innate immunity to most fungal infections 2. Important receptors include a lectin-like structure on phagocytes and Toll-like receptors 3. Most fungi are readily killed by phagocytes 4. Tissue phases of dimorphic fungi resist phagocytic killin ...
The Body`s Defenses - Life is a journey: Mr. T finding his way
The Body`s Defenses - Life is a journey: Mr. T finding his way

... • Natural Killer Cell – is similar to the CD8+ T Cell but it kills melanomas, lymphomas, viral- infected cells, and most herpes. • Granulocytes or Polymorphonuclear (PMN) Leukocytes - this cells contain of three cells (neutrophils, eosinophils, and basophils) they usually rid of parasites, and bacte ...
Tolerance - BHS116.3 Physiology III
Tolerance - BHS116.3 Physiology III

... • Tolerance is the process by which the body ensures that immune responses are directed against foreign or altered self antigens and not normal self. • It is defined as “the state of specific unresponsiveness of an individual to a particular antigenic epitope”. • Regulation of antigen-specific recep ...
May 14, 2011 Review for final exam (May 21, 2011, 8 AM) The final
May 14, 2011 Review for final exam (May 21, 2011, 8 AM) The final

... Enclosed below are multiple choice questions 64 to 145 and short answer questions 149-150 from last year’s final exam. These questions covered the material from the third portion of the course. The questions from last year’s final not included here (1-63 and 146-148) were drawn from the first two th ...
Enhancing the Innate Immune System with
Enhancing the Innate Immune System with

... all infections in general Specific innate immunity: This is a natural resistance to a particular kind of germ only. The major functions of the innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediat ...
Slide 1
Slide 1

... • Humoral immunity: – is mediated by molecules in the blood and mucosal secretions, called antibodies – against extracellular microbes and their toxins – Antibodies themselves are specialized, (phagocytosis and trigger the release of ...
cytotoxic T cells
cytotoxic T cells

... Though the destructive effects of electricity originate in several physical and physiological influences, even so the accidents can be classified into two groups: Electric shocks and injuries which may come off jointly. 1. Electric shock occurs when an electric current flowing through the body and c ...
Immunity
Immunity

... • In the regional lymph nodes the phagocytes present the antigen in association with MHC class I molecule to lymphocytes. • That is why phagocytes ( macrophages) are called antigen presenting cells (APC). ...
Specific Host Defense Mechanisms
Specific Host Defense Mechanisms

... Memory cells • Whether the body's response is primarily humoral (through antibodies) or cell-mediated, certain T and B cells become 'memory cells.' These cells remember their exposure to the specific antigens. This is the mechanism by which vaccination helps protect the body from disease. • 'prime' ...
Document
Document

... survive inside cells. Macrophages are a common targets for intracellular bacteria (e.g. Salmonella spp.) that live inside cell compartments. These bacteria cannot be detected by complement or antibody but, instead, are eliminated using a cell-mediated response. Infected macrophages present bacterial ...
VACCINES - Rovira i Virgili University
VACCINES - Rovira i Virgili University

... designed primarily for very young children because their immune systems can’t recognize the outer coats of certain bacteria. ...
Lymphatic System Notes
Lymphatic System Notes

... secretions can also defend – Mucous Membranes: Mucus and nasal hairs trap microorganisms; Cilia move mucus out of body; Gastric juice, saliva, and tears have ...
Immunit - El Camino College
Immunit - El Camino College

... 2. Most can survive outside a ________ with necessary requirements 3. _______________ can be used to kill most bacteria B. ___________ are not cellular; features are 1. Nucleic acid (______ or ______) core surrounded by a 2. ___________ coat of proteins 3. Some viruses have an additional ___________ ...
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Immunosuppressive drug

For a list of immunosuppressive drugs, see the transplant rejection page.Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act non-selectively, resulting in increased susceptibility to infections and decreased cancer immunosurveillance. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs.
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