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Endoplasmic Reticulum: An Interface Between the Immune System
Endoplasmic Reticulum: An Interface Between the Immune System

... participates in many important cellular tasks. It has been established that ER is involved in protein and lipid biosynthesis, calcium regulation, redox regulation, cell signaling, and cell death. Given the many vital and complex functions of ER, there is little wonder that its failure can trigger a ...
Canine Herpesvirus-1: A New Pathogenic Role for an Old Virus
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... palsy and the other on biomarkers for inflammatory bowel diseases and several patents. Dr. Satyaraj joined Nestle Purina in 2003 where he currently serves as a Senior Research Scientist at the Nestle Research Center conducting research in the area of nutritional immunology and cytokine biology. Dr. ...
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No Slide Title

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IL-1β inhibition in autoimmune inner ear disease: can you hear me
IL-1β inhibition in autoimmune inner ear disease: can you hear me

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Premature ovarian failure: Think `autoimmune disorder`
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Clinical Testing Suggestions - Institute for Molecular Medicine
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Body System Project - Mercer Island School District
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... Your group will create a power point to educate your classmates about the body system you are assigned. A rubric is provided at the end of this document. Your presentation should include:  The main function(s) of the body system  The main organs (or cell types) of this system and the function of e ...
Immunology: Introduction and Overview
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... fighting infection. ...
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IN AUTISM - Immunosciences Lab
IN AUTISM - Immunosciences Lab

... Evidence has been accumulating to suggest that the pathogenesis of some human diseases may be classified in terms of type-1 and type-2 T-helper cell cytokine profiles. For example, multiple sclerosis, type-1 diabetes, and arthritis are Th1 phenotypes, while allergy, chemical sensitivity, parasitic i ...
GRANULOMATOUS INFLAMMATION Lecture1
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Morphology of autoimmune hepatitis - pathologie
Morphology of autoimmune hepatitis - pathologie

... Kupffer cell hyperplasia: The so-called Kupffer cells are part of the immune system of the liver and can be found wherever there is an immune reaction. In cases of autoimmune hepatitis they are very often present as hyperplastic cell proliferates. ...
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Chapter 19: Disorders of the Immune System
Chapter 19: Disorders of the Immune System

... • foreign antigens that mimic self antigens • peptide antigens from certain viral and bacterial pathogens are very similar to specific self peptides • once an immune response is generated to pathogen, these T and B cells continue to respond to tissues expressing the similar self peptide ...
NAME OF LABORATORY: The Research Center for Digestive Tract
NAME OF LABORATORY: The Research Center for Digestive Tract

... Immune homeostatic responses in the intestinal mucosa. How does the intestinal epithelium respond to commensal flora (bacteria, fungi) and consequently activates the intestinal immune system. Identifying genetic, molecular, microbial, serologic, immune, nutritional and environmental factors associat ...
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... Regulation of Immune response, gene expression and disease prevention Drive for chronic inflammation and Disease Production: Obesity; autoimmunity; cancer Acute infection-inflammation Autism spectrum disorder _______________________ ...
Immune System Powerpoint
Immune System Powerpoint

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Autoimmunity

Autoimmunity is the system of immune responses of an organism against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease. Prominent examples include Celiac disease, diabetes mellitus type 1, Sarcoidosis, systemic lupus erythematosus (SLE), Sjögren's syndrome, Churg-Strauss Syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's Disease, rheumatoid arthritis (RA), Polymyositis (PM), and Dermatomyositis (DM). Autoimmune diseases are very often treated with steroids.The misconception that an individual's immune system is totally incapable of recognizing self antigens is not new. Paul Ehrlich, at the beginning of the twentieth century, proposed the concept of horror autotoxicus, wherein a ""normal"" body does not mount an immune response against its own tissues. Thus, any autoimmune response was perceived to be abnormal and postulated to be connected with human disease. Now, it is accepted that autoimmune responses are an integral part of vertebrate immune systems (sometimes termed ""natural autoimmunity""), normally prevented from causing disease by the phenomenon of immunological tolerance to self-antigens. Autoimmunity should not be confused with alloimmunity.
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