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... resistance and the developmental stage of the potato leaves tested. The aggressiveness of P. infestans isolates is likely to be affected by the length of time in axenic culture and it is thus important to ‘passage’ isolates on leaf material to restore aggressiveness prior to any experiment. Isolates ...
... resistance and the developmental stage of the potato leaves tested. The aggressiveness of P. infestans isolates is likely to be affected by the length of time in axenic culture and it is thus important to ‘passage’ isolates on leaf material to restore aggressiveness prior to any experiment. Isolates ...
Gene conversion analysis of the mouse Pilr locus
... Gene conversion has played a role in shaping the mouse Pilr locus and is detected by a variety of phylogenetic and statistical methods. Phylogenetic analysis of a conserved 3 kb region (the promoter through to intron 3) suggests that Pilrb1 and Pilrb2 are more related to each other than they are to ...
... Gene conversion has played a role in shaping the mouse Pilr locus and is detected by a variety of phylogenetic and statistical methods. Phylogenetic analysis of a conserved 3 kb region (the promoter through to intron 3) suggests that Pilrb1 and Pilrb2 are more related to each other than they are to ...
Sample Chapter
... (called bases and abbreviated A, T, C and G) that are repeated millions or billions of times throughout a genome. The human genome, for example, has 3 billion pairs of bases. In DNA, the particular order of As, Ts, Cs and Gs is extremely important. The order underlies the life’s diversity, even dict ...
... (called bases and abbreviated A, T, C and G) that are repeated millions or billions of times throughout a genome. The human genome, for example, has 3 billion pairs of bases. In DNA, the particular order of As, Ts, Cs and Gs is extremely important. The order underlies the life’s diversity, even dict ...
Poster Patrocles_V3
... Using positional cloning, we have recently identified the mutation responsible for muscular phenotype of the Texel sheep. It is located in the 3’UTR of the GDF8 gene - a known developmental repressor of muscle growth - and creates an illegitimate target site for miRNA expressed in the same tissue. T ...
... Using positional cloning, we have recently identified the mutation responsible for muscular phenotype of the Texel sheep. It is located in the 3’UTR of the GDF8 gene - a known developmental repressor of muscle growth - and creates an illegitimate target site for miRNA expressed in the same tissue. T ...
Week 8 - GEA
... • The program uses an underlying database (MSigDB) of about 11,000 gene sets that include KEGG, BIOCARTA pathways, curated sets from disease states, etc. ...
... • The program uses an underlying database (MSigDB) of about 11,000 gene sets that include KEGG, BIOCARTA pathways, curated sets from disease states, etc. ...
bbr038online 474..484 - Oxford Academic
... segments, which can confound orthology assignment and various laboratory experiments requiring the identification of individual genes. In this study, using the genome of a cartilaginous fish, Callorhinchus milii, as test case, we performed gene prediction using a model specifically trained for this ...
... segments, which can confound orthology assignment and various laboratory experiments requiring the identification of individual genes. In this study, using the genome of a cartilaginous fish, Callorhinchus milii, as test case, we performed gene prediction using a model specifically trained for this ...
Transvection in 2012: Site-Specific Transgenes Reveal a
... fragment stimulates transcription in a different row of cells. (B) Each transgene is inserted in the same chromosomal location. In this case, E2 stimulates transcription from the promoter on the other chromosome. Note that transcription does not occur in all blue cells. (C) In addition to enhancer a ...
... fragment stimulates transcription in a different row of cells. (B) Each transgene is inserted in the same chromosomal location. In this case, E2 stimulates transcription from the promoter on the other chromosome. Note that transcription does not occur in all blue cells. (C) In addition to enhancer a ...
A Long-Term Evolutionary Pressure on the Amount of Noncoding DNA
... the long-term evolvability of a lineage, for instance by promoting genomic rearrangements. They could thus be subject to an indirect selection. Yet, such a long-term effect is difficult to isolate either in vivo or in vitro. Here, by performing in silico experimental evolution, we demonstrate that, ...
... the long-term evolvability of a lineage, for instance by promoting genomic rearrangements. They could thus be subject to an indirect selection. Yet, such a long-term effect is difficult to isolate either in vivo or in vitro. Here, by performing in silico experimental evolution, we demonstrate that, ...
Newsletter - UC Cooperative Extension
... dominant to red coat color (bb). Crossing a homozygous dominant “BB” black bull to a homozygous recessive “bb” red cow will result in all heterozygous black “Bb” offspring. Many gene c defects are recessive, and the reason for this is that mutant alleles o en render the resul ng protein nonfunc ...
... dominant to red coat color (bb). Crossing a homozygous dominant “BB” black bull to a homozygous recessive “bb” red cow will result in all heterozygous black “Bb” offspring. Many gene c defects are recessive, and the reason for this is that mutant alleles o en render the resul ng protein nonfunc ...
Body maps on the human genome | SpringerLink
... The human genome may show “little evidence of organization” [1] and be in “an alarming state of disarray” [2], but it seems to have a global landscape, with largescale patterns encompassing all chromosomes together. One key to revealing this structure is chromosome territories, that is, their sites ...
... The human genome may show “little evidence of organization” [1] and be in “an alarming state of disarray” [2], but it seems to have a global landscape, with largescale patterns encompassing all chromosomes together. One key to revealing this structure is chromosome territories, that is, their sites ...
Section J Analysis and Uses of Cloned DNA
... Purpose: Some proteins that are known to be missing or defective in various disorders. These include growth hormone, insulin, interferon, blood clotting factor VIII and so on. Production of protein from a cloned gene can solve these problems. Main methods: • In bacteria: Initially, production in b ...
... Purpose: Some proteins that are known to be missing or defective in various disorders. These include growth hormone, insulin, interferon, blood clotting factor VIII and so on. Production of protein from a cloned gene can solve these problems. Main methods: • In bacteria: Initially, production in b ...
Examining the Process of de Novo Gene Birth
... the gene-birth continuum. To determine which genes are in the process of forming, the age of a gene can be estimated based on conservation with other species. The divergence of species during evolutionary history is a way of counting the passage of time (on a millions of years scale). If a particula ...
... the gene-birth continuum. To determine which genes are in the process of forming, the age of a gene can be estimated based on conservation with other species. The divergence of species during evolutionary history is a way of counting the passage of time (on a millions of years scale). If a particula ...
Tutorial for Interpretation of T-REx Results
... Goal: Find genes that connects contrasts (the cohesion of contrasts). This alternative for Venn Diagrams provides a clear overview of the number of genes shared by contrasts or that are specific for one contrast. The list of genes can be easily downloaded via a direct link in the cohesion of contras ...
... Goal: Find genes that connects contrasts (the cohesion of contrasts). This alternative for Venn Diagrams provides a clear overview of the number of genes shared by contrasts or that are specific for one contrast. The list of genes can be easily downloaded via a direct link in the cohesion of contras ...
Novartis Innovation Vol.3
... who leads a CART group at NIBR. It also might offer improved ways to turn off cell activity if patients have overly strong immune reactions, or to add other immunotherapy weaponry, Yang speculates. CRISPR’s Advantages and Drawbacks Compared with an earlier genome editing method called TALEN, the CRI ...
... who leads a CART group at NIBR. It also might offer improved ways to turn off cell activity if patients have overly strong immune reactions, or to add other immunotherapy weaponry, Yang speculates. CRISPR’s Advantages and Drawbacks Compared with an earlier genome editing method called TALEN, the CRI ...
Genome history in the symbiotic hybrid Euglena gracilis
... three groups is by the nearest neighbor method. In this approach, the gene is classified into the group of its closest related (i.e., most similar) sequence. We employed the nearest neighbor method by two approaches, first by using only sequence similarity — the nearest neighbor is the homologue wit ...
... three groups is by the nearest neighbor method. In this approach, the gene is classified into the group of its closest related (i.e., most similar) sequence. We employed the nearest neighbor method by two approaches, first by using only sequence similarity — the nearest neighbor is the homologue wit ...
Microbial Genetics - University of Montana
... – correlate with Inc group to prevent transfer of plasmids to recipients already carrying plasmids incompatible with donor cell plasmid ...
... – correlate with Inc group to prevent transfer of plasmids to recipients already carrying plasmids incompatible with donor cell plasmid ...
What is a gene, post-ENCODE? History and updated definition
... The classical view of a gene as a discrete element in the genome has been shaken by ENCODE The ENCODE consortium recently completed its characterization of 1% of the human genome by various high-throughput experimental and computational techniques designed to characterize functional elements (The EN ...
... The classical view of a gene as a discrete element in the genome has been shaken by ENCODE The ENCODE consortium recently completed its characterization of 1% of the human genome by various high-throughput experimental and computational techniques designed to characterize functional elements (The EN ...
29 August 2002
... tackle some thorny problems concerning evolutionary change. A recent study comparing humans, rats and mice3, for example, suggested that the rate of sequence divergence in mammals has been different for different chromosomes. Preliminary comparisons between the human genome and a sample of chimp DNA ...
... tackle some thorny problems concerning evolutionary change. A recent study comparing humans, rats and mice3, for example, suggested that the rate of sequence divergence in mammals has been different for different chromosomes. Preliminary comparisons between the human genome and a sample of chimp DNA ...
Genes and Genomes
... DNA markers 'mark' locations where DNA sequence varies (2 or more alleles) – Such polymorphisms can vary within and among individuals (e.g. heterozygotes vs. homozygotes) and populations ...
... DNA markers 'mark' locations where DNA sequence varies (2 or more alleles) – Such polymorphisms can vary within and among individuals (e.g. heterozygotes vs. homozygotes) and populations ...
probability and statistics
... principles to maize to produce numerous highly-productive strains; many of these are used today. Not only has genetics been important to maize, but maize has been important to genetics. Because of its economic value, maize has long been the subject of intensive genetic investigations. Many of the ba ...
... principles to maize to produce numerous highly-productive strains; many of these are used today. Not only has genetics been important to maize, but maize has been important to genetics. Because of its economic value, maize has long been the subject of intensive genetic investigations. Many of the ba ...
DNA Replication, Repair, and Recombination
... Due to the action of variable genetic elements, i.e. non-Mendelian inheritance 20 years later, evidence for mobile genetic elements in E. coli Transposable elements, transposons in prokaryotes and euk. Each transposon encodes for a transposase that catalyzes illegitimate recombination, because it re ...
... Due to the action of variable genetic elements, i.e. non-Mendelian inheritance 20 years later, evidence for mobile genetic elements in E. coli Transposable elements, transposons in prokaryotes and euk. Each transposon encodes for a transposase that catalyzes illegitimate recombination, because it re ...
Molecular cloning, characterization and expression analysis of WAG
... Floral organ formation has been the subject of intensive study for over 20 years, particularly in the model dicot species Arabidopsis thaliana and Antirrhinum majus. These studies have led to the establishment of a general model for the development of floral organs in higher plants. The so-called AB ...
... Floral organ formation has been the subject of intensive study for over 20 years, particularly in the model dicot species Arabidopsis thaliana and Antirrhinum majus. These studies have led to the establishment of a general model for the development of floral organs in higher plants. The so-called AB ...
Biotechnology-
... Recombinant DNA Technology: practice questions The following comprehension questions (at end of each chapter section) in Brooker, Concepts of Genetics are recommended: • Comprehension Questions (at end of each section): 19.1,19.2, 19.3. Answers to Comprehension Questions are at the very end of ever ...
... Recombinant DNA Technology: practice questions The following comprehension questions (at end of each chapter section) in Brooker, Concepts of Genetics are recommended: • Comprehension Questions (at end of each section): 19.1,19.2, 19.3. Answers to Comprehension Questions are at the very end of ever ...
Lecture 8
... * These paralogs are more similar to each other than to orthologs → result of duplication after the species split * The remaining 13% (=253 ORFs) perhaps older paralogs that have been lost in the other species due to specialisation ...
... * These paralogs are more similar to each other than to orthologs → result of duplication after the species split * The remaining 13% (=253 ORFs) perhaps older paralogs that have been lost in the other species due to specialisation ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.