Am. J. Physiol. 1989, 257, L47
... is the CF gene. Detection of genes in mammalian genomic DNA is complicated by two factors. Eukaryotic genes are broken into coding (exons) and noncoding (introns) segments, and some exons can be small, making them difficult to detect. Second, mammalian genomic DNA contains a variety of repetitive DN ...
... is the CF gene. Detection of genes in mammalian genomic DNA is complicated by two factors. Eukaryotic genes are broken into coding (exons) and noncoding (introns) segments, and some exons can be small, making them difficult to detect. Second, mammalian genomic DNA contains a variety of repetitive DN ...
annotation and analysis of newly discovered mycobacteriophage
... host. We are analyzing two novel mycobacteriophage, Firecracker and Dori, which were isolated on the UCSC campus using Mycobacterium Smegmatis as the viral host. After multiple rounds of plaque purification, we performed electron microscopy and observed that Dori has a typical siphoviral morphology ...
... host. We are analyzing two novel mycobacteriophage, Firecracker and Dori, which were isolated on the UCSC campus using Mycobacterium Smegmatis as the viral host. After multiple rounds of plaque purification, we performed electron microscopy and observed that Dori has a typical siphoviral morphology ...
S. latifolia sex-linked genes, p. 1 Evolutionary strata on
... duplicated from an autosomal gene (MATSUNAGA et al. 2003), and only one is degenerated (GUTTMAN and CHARLESWORTH 1998). The five X-linked genes so far mapped are arranged along a gradient of X-Y synonymous divergence (FILATOV 2005a), increasing with distance from the pseudo-autosomal region (FILATOV ...
... duplicated from an autosomal gene (MATSUNAGA et al. 2003), and only one is degenerated (GUTTMAN and CHARLESWORTH 1998). The five X-linked genes so far mapped are arranged along a gradient of X-Y synonymous divergence (FILATOV 2005a), increasing with distance from the pseudo-autosomal region (FILATOV ...
9 December, 2016 Regulations Review Office of the Gene
... nucleotide sequences from another organism, may be obtained by extended passage of micro-organisms under artificial conditions. Single nucleotide substitutions, gene deletions and sequence duplications occur in response to selection for growth under artificial conditions or due to the absence of sel ...
... nucleotide sequences from another organism, may be obtained by extended passage of micro-organisms under artificial conditions. Single nucleotide substitutions, gene deletions and sequence duplications occur in response to selection for growth under artificial conditions or due to the absence of sel ...
Saccharomyces Genome Database.
... about a locus includes the standard gene name, the systematic ORF name, and any aliases; Gene Ontology2'3 annotations describing the gene product's molecular functions, biological processes, and cellular components; additional brief information about the locus and gene product; phenotype information ...
... about a locus includes the standard gene name, the systematic ORF name, and any aliases; Gene Ontology2'3 annotations describing the gene product's molecular functions, biological processes, and cellular components; additional brief information about the locus and gene product; phenotype information ...
![[ 19] Saccharomyces Genome Database - SGD-Wiki](http://s1.studyres.com/store/data/012906934_1-a4c322e0bc64d409034f1882ecf44124-300x300.png)
[ 19] Saccharomyces Genome Database - SGD-Wiki
... about a locus includes the standard gene name, the systematic ORF name, and any aliases; Gene Ontology2'3 annotations describing the gene product's molecular functions, biological processes, and cellular components; additional brief information about the locus and gene product; phenotype information ...
... about a locus includes the standard gene name, the systematic ORF name, and any aliases; Gene Ontology2'3 annotations describing the gene product's molecular functions, biological processes, and cellular components; additional brief information about the locus and gene product; phenotype information ...
Bacteriophage l and Its Relatives
... a map of the l genome where one basis for this regulation can be seen, namely that the genes are clustered by function and organized into operons. This means that their transcription can be controlled in groups and from a small number of promoters. In l, all transcription is done by the host (E. col ...
... a map of the l genome where one basis for this regulation can be seen, namely that the genes are clustered by function and organized into operons. This means that their transcription can be controlled in groups and from a small number of promoters. In l, all transcription is done by the host (E. col ...
Sample pages 2 PDF
... A large number of virulence genes are contained on mobile genetic elements such as plasmids, bacteriophages, and DNA regions that are substrates for recombinases that allow their excision from a particular genome. For a number of pathogenic species, such as Vibrio cholera, Staphylococcus aureus, pat ...
... A large number of virulence genes are contained on mobile genetic elements such as plasmids, bacteriophages, and DNA regions that are substrates for recombinases that allow their excision from a particular genome. For a number of pathogenic species, such as Vibrio cholera, Staphylococcus aureus, pat ...
Transvection, nuclear structure, and chromatin proteins.
... transvection might persist long after the critical pairing event, as has been proposed by Sabl and Laird (1992). Zachar et al. (1985) also focus on events before transcription and propose that pairing functions to colocalize genes to the proper nuclear compartment. If diploidy or multigene families ...
... transvection might persist long after the critical pairing event, as has been proposed by Sabl and Laird (1992). Zachar et al. (1985) also focus on events before transcription and propose that pairing functions to colocalize genes to the proper nuclear compartment. If diploidy or multigene families ...
- The Boyle Lab
... As the sequencing of healthy and disease genomes becomes more commonplace, detailed annotation provides interpretation for individual variation responsible for normal and disease phenotypes. Current approaches focus on direct changes in protein coding genes, particularly nonsynonymous mutations that ...
... As the sequencing of healthy and disease genomes becomes more commonplace, detailed annotation provides interpretation for individual variation responsible for normal and disease phenotypes. Current approaches focus on direct changes in protein coding genes, particularly nonsynonymous mutations that ...
Kernels for gene regulatory regions
... In a eukaryotic cell, a variety of DNA switches—promoters, enhancers, silencers, etc.— regulate the production of proteins from DNA. These switches typically contain multiple binding site motifs, each of length 5–15 nucleotides, for a class of DNA-binding proteins known as transcription factors. As ...
... In a eukaryotic cell, a variety of DNA switches—promoters, enhancers, silencers, etc.— regulate the production of proteins from DNA. These switches typically contain multiple binding site motifs, each of length 5–15 nucleotides, for a class of DNA-binding proteins known as transcription factors. As ...
Natural Transfer of Conjugative Transposon Tn916 between Gram
... The data presented in this report provide evidence that the streptococcal conjugative transposon Tn916 is able to cross naturally the barrier between a variety of gram-positive and gram-negative eubacteria, with subsequent expression in the new host. Although we did not make any attempt to determine ...
... The data presented in this report provide evidence that the streptococcal conjugative transposon Tn916 is able to cross naturally the barrier between a variety of gram-positive and gram-negative eubacteria, with subsequent expression in the new host. Although we did not make any attempt to determine ...
synthesis Gene Cluster of Streptomyces clavuligerus
... Characteristics of argD ORF4 (1203 nt with a G+C content of 71.3%) encodes a 400 amino acid protein with a calculated Mr of 41,972. The argB stop codon overlaps with the initiation codon of ORF3. A search in the Swiss-Prot database with the FASTA Program revealed that the protein encoded by ORF3 has ...
... Characteristics of argD ORF4 (1203 nt with a G+C content of 71.3%) encodes a 400 amino acid protein with a calculated Mr of 41,972. The argB stop codon overlaps with the initiation codon of ORF3. A search in the Swiss-Prot database with the FASTA Program revealed that the protein encoded by ORF3 has ...
The WD40-Repeat Proteins NFC101 and NFC102
... (ZCN8), key activators of the floral transition. In addition, the abolition of NFC101/NFC102 association with repetitive sequences of different transposable elements (TEs) resulted in tissue-specific upregulation of nonpolyadenylated RNAs produced by these regions. All direct nfc101/nfc102 targets sho ...
... (ZCN8), key activators of the floral transition. In addition, the abolition of NFC101/NFC102 association with repetitive sequences of different transposable elements (TEs) resulted in tissue-specific upregulation of nonpolyadenylated RNAs produced by these regions. All direct nfc101/nfc102 targets sho ...
Identification of a Class of Chromatin Boundary Elements
... limiting their action to the domain in which they reside. The biological activity of a boundary element is experimentally measured by either position-independent expression or enhancerblocking assays. If this view of chromosomal organization is correct, boundary elements play a very important functi ...
... limiting their action to the domain in which they reside. The biological activity of a boundary element is experimentally measured by either position-independent expression or enhancerblocking assays. If this view of chromosomal organization is correct, boundary elements play a very important functi ...
DNA constructs designed to produce short hairpin, interfering RNAs
... from positions ± 10 to ± 15. The targeted sequences for Nat1 and Nat2 (Table 1) fit these specifications quite well. However, the target sequence for NAT1 (a human transgene present in other lines), does not fit these specifications since it was G-C rich in those internal positions. Other aspects of ...
... from positions ± 10 to ± 15. The targeted sequences for Nat1 and Nat2 (Table 1) fit these specifications quite well. However, the target sequence for NAT1 (a human transgene present in other lines), does not fit these specifications since it was G-C rich in those internal positions. Other aspects of ...
Masters_Thesis_Final - JScholarship
... over 3500 associated SNPs, shows that about 88% of these SNPs lie within non-coding region of the genome [5]. These non-coding variants are hypothesized to lie in regulatory regions of the genome, which regulate gene expression. So, the aim to identify the causal variation would be a step closer if ...
... over 3500 associated SNPs, shows that about 88% of these SNPs lie within non-coding region of the genome [5]. These non-coding variants are hypothesized to lie in regulatory regions of the genome, which regulate gene expression. So, the aim to identify the causal variation would be a step closer if ...
The Close Relationship Between the A and B Genomes in Avena L
... morphology of the genus Aena, did not support the autoploid origin of the barbata group tetraploids from the strigosa group of diploids as previously suggested by Oinuma (1952). Karyotypic observation confirmed the presence of an A. strigosa chromosome set (As genome) in the barbata group tetraploi ...
... morphology of the genus Aena, did not support the autoploid origin of the barbata group tetraploids from the strigosa group of diploids as previously suggested by Oinuma (1952). Karyotypic observation confirmed the presence of an A. strigosa chromosome set (As genome) in the barbata group tetraploi ...
Evolution by gene duplication: an update
... lacks necessary elements for transcription and thus immediately becomes a pseudogene. Nevertheless, several retroposition-mediated duplicate genes are expressed, probably because of the chance insertion of cDNA into a genomic location that is downstream of a promoter sequence [17]. Chromosomal or ge ...
... lacks necessary elements for transcription and thus immediately becomes a pseudogene. Nevertheless, several retroposition-mediated duplicate genes are expressed, probably because of the chance insertion of cDNA into a genomic location that is downstream of a promoter sequence [17]. Chromosomal or ge ...
Integrons and the Origin of Antibiotic Resistance Gene Cassettes
... of Xanthomonas and Vibrio SIs (Fig. 3). Once mobile, one can imagine that the subsequent harvesting of cassettes from various SI sources led to contemporary RIs, including the great diversity of attC sites associated with these gene cassettes. Two recent observations support this account of how RIs ...
... of Xanthomonas and Vibrio SIs (Fig. 3). Once mobile, one can imagine that the subsequent harvesting of cassettes from various SI sources led to contemporary RIs, including the great diversity of attC sites associated with these gene cassettes. Two recent observations support this account of how RIs ...
Genes without frontiers?
... Ochman et al, 2000; Gogarten et al, 2002). This evolution need not be slow. The intense selection pressure imposed on microbial communities by worldwide antibiotic use reveals that new multiresistance plasmids can arise from diverse origins and spread in less than five decades (Hartl and Dykhuizen, ...
... Ochman et al, 2000; Gogarten et al, 2002). This evolution need not be slow. The intense selection pressure imposed on microbial communities by worldwide antibiotic use reveals that new multiresistance plasmids can arise from diverse origins and spread in less than five decades (Hartl and Dykhuizen, ...
The Macaque Genome: Lessons from Comparative
... characteristics are derived from a given organism's DNA, or genome. That means that the finer details about the relatedness among organisms and the traits that make them similar or different, can often be inferred by examining them at the DNA level, i.e., by looking at their DNA sequences. Comparing ...
... characteristics are derived from a given organism's DNA, or genome. That means that the finer details about the relatedness among organisms and the traits that make them similar or different, can often be inferred by examining them at the DNA level, i.e., by looking at their DNA sequences. Comparing ...
Genetic Imprinting in Maize Bhavani P1*, Harinikumar K. M1
... phenotype while maternally inherited R allele gives solid phenotype (Kermicle, 1970). The imprinting of R allele appears to be due to differential expression of the maternal allele in relation to paternal allele rather than silencing of paternal allele (Kermicle and Alleman, 1990). Alpha-tubulin gen ...
... phenotype while maternally inherited R allele gives solid phenotype (Kermicle, 1970). The imprinting of R allele appears to be due to differential expression of the maternal allele in relation to paternal allele rather than silencing of paternal allele (Kermicle and Alleman, 1990). Alpha-tubulin gen ...
Chapter 3 Transposon Mutagenesis of Rhodobacter sphaeroides
... transposition happens at a frequency of 10-4 to 10-7, it is important to eliminate the vast majority of organisms that do not have an insertion before proceeding. Finally, transposons cause very clean mutations. When an organism is mutagenized with chemicals or irradiated, it is possible to get more ...
... transposition happens at a frequency of 10-4 to 10-7, it is important to eliminate the vast majority of organisms that do not have an insertion before proceeding. Finally, transposons cause very clean mutations. When an organism is mutagenized with chemicals or irradiated, it is possible to get more ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.