The search for small regulatory RNA
... siRNA – Inhibits expression of exogenous genes RNAi – Human exploitation of phenomenon miRNA – Inhibits expression of endogenous genes ...
... siRNA – Inhibits expression of exogenous genes RNAi – Human exploitation of phenomenon miRNA – Inhibits expression of endogenous genes ...
Identification of genes that are associated with DNA repeats in
... contrast, cas homologues were absent from any of the completely sequenced CRISPR-negative genomes, illustrating the strong association of cas genes and CRISPR loci (see Table 1). No CRISPR loci were identified in eukaryotic genomes and, as expected, no homologues of the cas genes were found in these ...
... contrast, cas homologues were absent from any of the completely sequenced CRISPR-negative genomes, illustrating the strong association of cas genes and CRISPR loci (see Table 1). No CRISPR loci were identified in eukaryotic genomes and, as expected, no homologues of the cas genes were found in these ...
Effects of Genic Base Composition on Growth Rate in G+C
... not necessarily toward higher G+C); however, genome comparisons have shown that selection for increased G+C contents also acts on "silent" sites, i.e., noncoding DNA and synonymous codon positions, previously assumed to evolve in a neutral manner. We adopted an experimental approach to study the eff ...
... not necessarily toward higher G+C); however, genome comparisons have shown that selection for increased G+C contents also acts on "silent" sites, i.e., noncoding DNA and synonymous codon positions, previously assumed to evolve in a neutral manner. We adopted an experimental approach to study the eff ...
Rapid divergence and diversification of mammalian duplicate gene
... should be lost within the first few million years of evolution [36]. In Drosophila, many neofunctionalized child genes likely arose with or quickly acquired new beneficial functions that were retained by natural selection [10]. In mammals, for which natural selection is less efficient, such genes ma ...
... should be lost within the first few million years of evolution [36]. In Drosophila, many neofunctionalized child genes likely arose with or quickly acquired new beneficial functions that were retained by natural selection [10]. In mammals, for which natural selection is less efficient, such genes ma ...
Divergent evolution of oxidosqualene cyclases in plants
... Morlacchi et al., 2009). Thus a remarkable amount of chemical diversity is derived from a single substrate 2,3-oxidosqualene. Over the last 16 yr, OSCs have been characterized from a diverse range of plant species. The 13 A. thaliana OSCs and their major cyclization products are summarized in Table ...
... Morlacchi et al., 2009). Thus a remarkable amount of chemical diversity is derived from a single substrate 2,3-oxidosqualene. Over the last 16 yr, OSCs have been characterized from a diverse range of plant species. The 13 A. thaliana OSCs and their major cyclization products are summarized in Table ...
Advances in maize genomics: the emergence of positional cloning
... maize and teosinte to five major QTL. One of these QTL mapped to the region containing teosinte branched1 (tb1), whose mutant phenotype suggests that it is an excellent candidate gene. Cloning of the gene and analysis of both maize and teosinte alleles has supported tb1 as the gene for this QTL [37, ...
... maize and teosinte to five major QTL. One of these QTL mapped to the region containing teosinte branched1 (tb1), whose mutant phenotype suggests that it is an excellent candidate gene. Cloning of the gene and analysis of both maize and teosinte alleles has supported tb1 as the gene for this QTL [37, ...
Divergent evolution of oxidosqualene cyclases in plants
... Morlacchi et al., 2009). Thus a remarkable amount of chemical diversity is derived from a single substrate 2,3-oxidosqualene. Over the last 16 yr, OSCs have been characterized from a diverse range of plant species. The 13 A. thaliana OSCs and their major cyclization products are summarized in Table ...
... Morlacchi et al., 2009). Thus a remarkable amount of chemical diversity is derived from a single substrate 2,3-oxidosqualene. Over the last 16 yr, OSCs have been characterized from a diverse range of plant species. The 13 A. thaliana OSCs and their major cyclization products are summarized in Table ...
Woods Hole – Zebrafish Genetics and Development Bioinformatics
... in situ hybridization. In addition, many other tissues express GFP. Encouraged by this result, you raise the embryos to adulthood and cross them to identify founders. You identify ten founders, but none of your lines express GFP in a pattern consistent with the in situ data: expression in some tissu ...
... in situ hybridization. In addition, many other tissues express GFP. Encouraged by this result, you raise the embryos to adulthood and cross them to identify founders. You identify ten founders, but none of your lines express GFP in a pattern consistent with the in situ data: expression in some tissu ...
A Comparative Gene Map of the Horse (Equus caballus)
... Type I loci In addition to amplifying gene-specific fragments, a key feature necessary for the effective use of PCR-based markers in synteny mapping with interspecific SCH panels is the ability to differentiate between fragments amplified from the donor species (i.e. horse) and the murine background ...
... Type I loci In addition to amplifying gene-specific fragments, a key feature necessary for the effective use of PCR-based markers in synteny mapping with interspecific SCH panels is the ability to differentiate between fragments amplified from the donor species (i.e. horse) and the murine background ...
Developmental Biology BY1101 P. Murphy Lecture 10 Master
... •And chromosomal arrangement of the genes is conserved. •They have also conserved the order and relative position along the AP axis of the embryo where they are expressed and function (colinearity) The genes are in fact so closely similar that the mouse version of one gene has been transferred to th ...
... •And chromosomal arrangement of the genes is conserved. •They have also conserved the order and relative position along the AP axis of the embryo where they are expressed and function (colinearity) The genes are in fact so closely similar that the mouse version of one gene has been transferred to th ...
A virulence-associated gene microarray: a tool for
... Staphylococcus aureus strains has been constructed. The array comprises 383 probes based on virulence-associated genes present in four key strains. Twelve strains including seven for which the complete chromosomal nucleotide sequence was available were tested on the array. Twenty-six per cent of the ...
... Staphylococcus aureus strains has been constructed. The array comprises 383 probes based on virulence-associated genes present in four key strains. Twelve strains including seven for which the complete chromosomal nucleotide sequence was available were tested on the array. Twenty-six per cent of the ...
Author`s personal copy - Real Jardín Botánico
... rather assignable almost solely to seed plants. We show that early diverging land plants and presumably streptophyte algae share a co-localization of all rRNA genes within one repeat unit. This raises the possibility that the state of rDNA gene co-localization had occurred in their common ancestor. ...
... rather assignable almost solely to seed plants. We show that early diverging land plants and presumably streptophyte algae share a co-localization of all rRNA genes within one repeat unit. This raises the possibility that the state of rDNA gene co-localization had occurred in their common ancestor. ...
S1 Supporting Information
... The amplified 5.1 kb fragment was BglII digested and ligated with the 3.4 kb pyrG fragment to give plasmid pMAT768. A 5.5 kb replacement fragment harboring the pyrG gene flanked by 1.1 kb and 1.0 kb of sequences adjacent to 136157 was released from plasmid pMAT768 by PvuII digestion, amplified with ...
... The amplified 5.1 kb fragment was BglII digested and ligated with the 3.4 kb pyrG fragment to give plasmid pMAT768. A 5.5 kb replacement fragment harboring the pyrG gene flanked by 1.1 kb and 1.0 kb of sequences adjacent to 136157 was released from plasmid pMAT768 by PvuII digestion, amplified with ...
PDF - WashU Epigenome Browser
... Learn more about the supported numerical track formats bedGraph (http: //wiki.wubrowse.org/bedgraph) and bigWig (http://wiki.wubrowse.org/bigwig). ...
... Learn more about the supported numerical track formats bedGraph (http: //wiki.wubrowse.org/bedgraph) and bigWig (http://wiki.wubrowse.org/bigwig). ...
PDF
... homonomous - though there is at present no way of knowing where to place that ancestor on the phylogenetic tree. We do question whether homonomy is generally a primitive trait among extant arthropods. In an environment where it is useful for all segments to have legs, this adaptive change may be rel ...
... homonomous - though there is at present no way of knowing where to place that ancestor on the phylogenetic tree. We do question whether homonomy is generally a primitive trait among extant arthropods. In an environment where it is useful for all segments to have legs, this adaptive change may be rel ...
Sorting Out the Genome
... Mathematical graph theory is the primary tool for calculating reversal distance. A graph consists of vertices (or dots) and edges (lines that connect the vertices). In this graph of a 10-element unsigned permutation (with additional anchoring elements 0 and 11) there are two kinds of edges. Solid ed ...
... Mathematical graph theory is the primary tool for calculating reversal distance. A graph consists of vertices (or dots) and edges (lines that connect the vertices). In this graph of a 10-element unsigned permutation (with additional anchoring elements 0 and 11) there are two kinds of edges. Solid ed ...
Dual-Tagging Gene Trap of Novel Genes in Drosophila
... exhibiting reporter gene expression than enhancer-trap systems. In the enhancer-trap system, the reporter gene is expressed regardless of its orientation relative to the inserted gene, whereas in the gene-trap system, the vector needs to be integrated in the same orientation as the trapped gene (see ...
... exhibiting reporter gene expression than enhancer-trap systems. In the enhancer-trap system, the reporter gene is expressed regardless of its orientation relative to the inserted gene, whereas in the gene-trap system, the vector needs to be integrated in the same orientation as the trapped gene (see ...
Evolutionary analysis of the female
... more than 1.5 times the interquartile distance. Outliers exceed this limit. ...
... more than 1.5 times the interquartile distance. Outliers exceed this limit. ...
A.3.1.5SecretsInGenes - Life Science Academy
... A logarithm is the power to which a base must be raised to produce a desired value. In the case of a base 2 logarithm, for every increase or decrease of one, there is a two fold change. For example: Log2(0.0625) = -4 Log2(0.125) = -3 Log2(0.25) = -2 Log2(0.5) = -1 Log2(1) = 0 Log2(2) = 1 Log2(4) = 2 ...
... A logarithm is the power to which a base must be raised to produce a desired value. In the case of a base 2 logarithm, for every increase or decrease of one, there is a two fold change. For example: Log2(0.0625) = -4 Log2(0.125) = -3 Log2(0.25) = -2 Log2(0.5) = -1 Log2(1) = 0 Log2(2) = 1 Log2(4) = 2 ...
Characterization of the Human Gene for a Newly Discovered
... corresponding regions of the human CA I, CA II, and CA III proteins, respectively. This region of the carbonic anhydrases is precisely encoded by exon 6 of all other characterized vertebrate CA genes (Tashian et al., 1990; Hewett-Emmett and Tashian, 1991). Additional potential coding material, which ...
... corresponding regions of the human CA I, CA II, and CA III proteins, respectively. This region of the carbonic anhydrases is precisely encoded by exon 6 of all other characterized vertebrate CA genes (Tashian et al., 1990; Hewett-Emmett and Tashian, 1991). Additional potential coding material, which ...
ppt - Chair of Computational Biology
... Detect syntenic regions with PatternHunter - perform sequence comparison of entire mouse and human genome sequences to identify regions with a high similarity score > 40 (corresponding to a 40-base perfect match with penalties for mismatches and gaps) - also require that each sequence is the other‘ ...
... Detect syntenic regions with PatternHunter - perform sequence comparison of entire mouse and human genome sequences to identify regions with a high similarity score > 40 (corresponding to a 40-base perfect match with penalties for mismatches and gaps) - also require that each sequence is the other‘ ...
Monooxygenases in the Butane and Cyclohexane Degradation
... until now. Studies indicated that this enzyme could be related to the soluble butane monooxygenase. The cyclohexane pathway contains a second monooxygenase, type: Baeyer-Villiger monooxygenase (BVO). The sequences of many of these enzymes are published, their sequences are diverse. The enrichment of ...
... until now. Studies indicated that this enzyme could be related to the soluble butane monooxygenase. The cyclohexane pathway contains a second monooxygenase, type: Baeyer-Villiger monooxygenase (BVO). The sequences of many of these enzymes are published, their sequences are diverse. The enrichment of ...
Chromosomal theory of inheritance
... Non-‐Mendelian Inheritance • Ques*on 10: What are Bateson’s three types of non-‐Mendelian inheritance? • Blended inheritance or con*nuous varia*on: mul*ple genes influence a trait. • First crosses that breed true: ...
... Non-‐Mendelian Inheritance • Ques*on 10: What are Bateson’s three types of non-‐Mendelian inheritance? • Blended inheritance or con*nuous varia*on: mul*ple genes influence a trait. • First crosses that breed true: ...
cis667-10
... • The reversal distance of oriented permutations is given by: • d(a) = n + 1 - c(a) + h(a) + f(a) c(a) - number of cycles (proper and non) h(a) - number of hurdles f(a) - a a fortress? (1 else 0) n + 1 - c(a) good components and bad components which become good during sort h(a) - bad compo ...
... • The reversal distance of oriented permutations is given by: • d(a) = n + 1 - c(a) + h(a) + f(a) c(a) - number of cycles (proper and non) h(a) - number of hurdles f(a) - a a fortress? (1 else 0) n + 1 - c(a) good components and bad components which become good during sort h(a) - bad compo ...
P.abyssi PDF version
... (Lucas et al., 2003). Pyrococcus abyssi and closely related strain devoid of plasmids (e.g. GE9) appear thus promising species to develop genetic tools for hyperthermophiles. The complete genome of P. abyssi GE5 (deposited at the CNCM under strain Orsay) has been sequenced at Genoscope in 1998 and r ...
... (Lucas et al., 2003). Pyrococcus abyssi and closely related strain devoid of plasmids (e.g. GE9) appear thus promising species to develop genetic tools for hyperthermophiles. The complete genome of P. abyssi GE5 (deposited at the CNCM under strain Orsay) has been sequenced at Genoscope in 1998 and r ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.