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Models in Genetics - Cherokee High School
Models in Genetics - Cherokee High School

... enthusiast began to breed mice in the early 1900’s for their interesting fur colors.  Harvard University began to use them in research  This led indirectly to the development of Jackson Laboratories in Maine ...
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... piercing prey and sucking the juices out of them. All developing probosci express the pb Hox gene. How would you explain the morphological diversity of these structures? 6. A human patient presents with polydactyly, six fingers on each hand. Why is this likely to be a regulatory mutation and not due ...
Protocol S1
Protocol S1

... putative GI width must be over 15 kb; 2) the G+C% of the potential GI must have over 4.5 differences greater or smaller than the G+C% of S. suis P1/7. To determine possible sources of horizontally transferred GIs, we performed BLASTN. If the hit nucleotide sequence had >80% identity with the possibl ...
슬라이드 1
슬라이드 1

... Fig. 2. RT-PCR analysis of LTR10A derived transcript (A) and methylation analysis (B) from different human tissues. Methylation state of all cytosines in the CpG sequences was analyzed by the bisulfite-modified DNA sequencing method. Each nucleotide position is symbolized by a circle representing th ...
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... Only a small amount (percentage) of human DNA contains information that is ostensibly converted into proteins: these sequences are associated with genes. The proteins coded for by genes do biochemical work and regulate cell division, generate energy, respond to the environment, provide immunity to i ...
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... • Transposons make up 40 percent of human genome, only 3 - 10 percent in other sequenced eukaryotes • Transposons are not tandemly repeated but, rather, exist as isolated elements that may be present in many thousands of copies per genome. • SINEs (short interspersed elements) range in length from 1 ...
The Good, the bad and the ugly of Genetic Engineering
The Good, the bad and the ugly of Genetic Engineering

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Lecture8-Chap5 Sept26
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... enzymes to cleave regions that contain short repeated sequences, or by PCR. – The lengths of the repeated regions are unique to every individual. – The presence of a particular subset in any two individuals can be used to define their common inheritance (e.g., a parent–child relationship). ...
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D. melanogaster

... “In many ways we are like children in an enchanted forest, wandering almost aimlessly from discovery to discovery. For the moment, at least, that should be sufficient. At some point we will inevitably emerge into a clearing where principles and patterns in the organization and evolution of the geno ...
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The Little Things About the Little Things Inside of Us The Eukaryotic

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... a) Which alignment would you consider more likely to identify a homologous gene, and why? The first alignment shows identity over a long stretch, and only two molecular changes differentiate the sequences. The large number of gaps may suggest that the function of the gene has changed, but these are ...
Human Genome Project
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... from another organism, it has been evolutionarily conserved, and that usually means that it is an expressed gene. Exon prediction: exons need to be open reading frames (no stop codons), and they display patterns of nucleotide usage different from random DNA. Several different programs exist, and the ...
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1. Compare the organization of prokaryotic and

... 5. Describe where satellite DNA is found and what role it may play in the cell. • Satellite DNA  highly repetitive DNA consisting of short unusual nucleotide sequences that are tandemly repeated 1000’s of times • It is found at the tips of chromosomes and the centromere • Its function is not known ...
1. Compare the organization of prokaryotic and eukaryotic genomes.
1. Compare the organization of prokaryotic and eukaryotic genomes.

... 5. Describe where satellite DNA is found and what role it may play in the cell. • Satellite DNA  highly repetitive DNA consisting of short unusual nucleotide sequences that are tandemly repeated 1000’s of times • It is found at the tips of chromosomes and the centromere • Its function is not known ...
ppt - Barley World
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... A low pressure helium pulse delivers the coated gold particles into virtually any target cell or tissue. The particles carry the DNA so that you do not have to remove cells from tissue in order to transform the cells.” ...
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Sequencing genomes

... conservation and variation can be identified. • The degree of sequence conservation in the alignment reveals evolutionary relatedness of different sequences • The variation between sequences reflects the changes that have occurred during evolution in the form of substitutions and/or indels. • Identi ...
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Supplemental Information - Molecular Cancer Research

... Fisher's exact test computes a 2-tailed p-value = 0.000261. The gene universe used in this calculation (~22,000) is not an exact known number. However, running the test with a smaller gene universe (20,000) or a larger gene universe (30,000) still generates a significant p-value (20,000 p-value = 0. ...
Unit2Day5
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... 169 different genes with expression differences between human and chimp in cortex Most genes were more highly expressed in human vs. chimp Caceres et al., 2003, PNAS, 100: 13030-13035 ...
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Transcription Regulation (Prof. Fridoon)
Transcription Regulation (Prof. Fridoon)

... Many genes also have enhancer (1000 nucleotide away) where specific activators only made by certain cells can bind. ...
11-GeneTech
11-GeneTech

... What can cloned genes be used for? Transferring to other organisms, e.g. -- insulin production to bacteria -- herbicide/ insect resistance to plants -- crop yield & nutritional value (e.g. ‘golden rice’) -- biofuel (e.g., rape seed oil) ...
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Transposable element



A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.
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