Human polyomavirus JC control region variants in persistently
... from brain parenchyma and from the renal medulla of patients with CNS diseases other than PML or with systemic disorders (Table 1). In none of the cases, neurological symptoms or histopathological patterns indicative of PML were observed. Cellular DNA was subjected to amplification of JCV DNA. One p ...
... from brain parenchyma and from the renal medulla of patients with CNS diseases other than PML or with systemic disorders (Table 1). In none of the cases, neurological symptoms or histopathological patterns indicative of PML were observed. Cellular DNA was subjected to amplification of JCV DNA. One p ...
Single-molecule studies of DNA replication Geertsema, Hylkje
... replication proteins are stably bound and re-used for many cycles of Okazakifragment synthesis. Such a mechanism provides an attractive model for coordinated synthesis of both strands. Dilution experiments of T7 DNA replication reactions showed that both leading- and lagging-strand synthesis are res ...
... replication proteins are stably bound and re-used for many cycles of Okazakifragment synthesis. Such a mechanism provides an attractive model for coordinated synthesis of both strands. Dilution experiments of T7 DNA replication reactions showed that both leading- and lagging-strand synthesis are res ...
Section E
... sites which arrest the movement of the forks by binding the tus gene product, which is an inhibitor of the DnaB helicase; – Hence, if one fork is delayed for some reason, they will still meet within the terminus. • Segregation: – Topoisomerase IV: Once replication is completed, the two daughter circ ...
... sites which arrest the movement of the forks by binding the tus gene product, which is an inhibitor of the DnaB helicase; – Hence, if one fork is delayed for some reason, they will still meet within the terminus. • Segregation: – Topoisomerase IV: Once replication is completed, the two daughter circ ...
DNA - UCSF Tetrad Program
... residual activity in a polA1 mutant may be sufficient. Note, although polA1 has an early nonsense mutation, read-through of the nonsense codon is suspected of generating the residual Pol I activity ...
... residual activity in a polA1 mutant may be sufficient. Note, although polA1 has an early nonsense mutation, read-through of the nonsense codon is suspected of generating the residual Pol I activity ...
Solutions to Genetics Day 6 Interpretation Questions
... If observations were inconsistent with their expectations, you should consider the possibility that their Ara- and KanR phenotypes were not linked. 2. Consider wild type λ phage, the modified λ phage that carried the mini TN10 transposon, the P1 phage we used to make lysates and the P1 phage found i ...
... If observations were inconsistent with their expectations, you should consider the possibility that their Ara- and KanR phenotypes were not linked. 2. Consider wild type λ phage, the modified λ phage that carried the mini TN10 transposon, the P1 phage we used to make lysates and the P1 phage found i ...
Plant Virus RNAs. Coordinated Recruitment of Conserved Host
... which binds eIF1A; the involvement of eIF1A is important as mutations that reduce the binding also reduce (2) strand synthesis and virus accumulation. The exact mechanism is not clear but eIF1A might stimulate replication in association with other host factors (see Zeenko et al., 2002). eIF1A is als ...
... which binds eIF1A; the involvement of eIF1A is important as mutations that reduce the binding also reduce (2) strand synthesis and virus accumulation. The exact mechanism is not clear but eIF1A might stimulate replication in association with other host factors (see Zeenko et al., 2002). eIF1A is als ...
DNA-dependent DNA polymerase (DDDP)
... • Enzymes use two mechanisms to ensure the replication fidelity. – Proofreading and real-time correction ...
... • Enzymes use two mechanisms to ensure the replication fidelity. – Proofreading and real-time correction ...
The Replication of DNA
... called the origin recognition complex (ORC). Subunits are named according to their size, with ORC1 being the largest and ORC6 being the smallest subunit. ORC recongnizes a conserved sequence A element, as well as a less- conserved B1 element. 整个细胞周期中 ...
... called the origin recognition complex (ORC). Subunits are named according to their size, with ORC1 being the largest and ORC6 being the smallest subunit. ORC recongnizes a conserved sequence A element, as well as a less- conserved B1 element. 整个细胞周期中 ...
Chicago Department of Public Health
... Noroviruses are a group of viruses that cause the “stomach flu,” or gastroenteritis in people. The term norovirus was recently approved as the official name for this group of viruses. Several other names have been used for noroviruses, including: Norwalk-like viruses (NLVs) caliciviruses (beca ...
... Noroviruses are a group of viruses that cause the “stomach flu,” or gastroenteritis in people. The term norovirus was recently approved as the official name for this group of viruses. Several other names have been used for noroviruses, including: Norwalk-like viruses (NLVs) caliciviruses (beca ...
The S RNA segment of tomato spotted wilt virus has an ambisense
... Analysis of the six different reading frames of the viral and viral complementary R N A strand revealed two long open reading frames (ORFs), one on each strand. No additional ORFs of significant length (i.e. ORFs encoding proteins larger than 5K) could be detected in any of the other reading frames ...
... Analysis of the six different reading frames of the viral and viral complementary R N A strand revealed two long open reading frames (ORFs), one on each strand. No additional ORFs of significant length (i.e. ORFs encoding proteins larger than 5K) could be detected in any of the other reading frames ...
Envelope gene sequences encoding variable regions 3 and 4 are
... lymphocytes and macrophages (Beebe et al., 1994 ; Dean et al., 1996 ; English et al., 1993). The envelope glycoprotein plays a key role in the initial virus–cell interaction, although other virus proteins may also be involved. The tropism of FIV for CRFK cells has been shown to be affected by the th ...
... lymphocytes and macrophages (Beebe et al., 1994 ; Dean et al., 1996 ; English et al., 1993). The envelope glycoprotein plays a key role in the initial virus–cell interaction, although other virus proteins may also be involved. The tropism of FIV for CRFK cells has been shown to be affected by the th ...
Mugisha, L., Leendertz, FH, Opuda-Asibo, J., Olobo, JO, Ehlers, B. A
... players involved in diseases threatening the health of nonhuman primates [11, 20]. Herpesviruses may play an important role in multifactorial disease progressions, and despite various discoveries of novel herpesviruses in wild great apes and other primates [8, 18, 20], the spectrum of herpesviruses ...
... players involved in diseases threatening the health of nonhuman primates [11, 20]. Herpesviruses may play an important role in multifactorial disease progressions, and despite various discoveries of novel herpesviruses in wild great apes and other primates [8, 18, 20], the spectrum of herpesviruses ...
DNA Replication
... DNA – deoxyribonucleic acid is the nucleic acid that stores and transmits genetic info. from one generation to the next. •present in all organisms, but different (unique) in each individual, except for identical twins. ...
... DNA – deoxyribonucleic acid is the nucleic acid that stores and transmits genetic info. from one generation to the next. •present in all organisms, but different (unique) in each individual, except for identical twins. ...
sequence DNA - DigitalCommons@University of Nebraska
... also be noted that microelectronics fabrication has had an impact on other biomedical technologies by massive miniaturization of fluid processing. These developments are referred as ‘lab-on-a-chip’ (Burns et al 1998). Thus it is conjectured that in the future a combination of microfluidics (i.e. la ...
... also be noted that microelectronics fabrication has had an impact on other biomedical technologies by massive miniaturization of fluid processing. These developments are referred as ‘lab-on-a-chip’ (Burns et al 1998). Thus it is conjectured that in the future a combination of microfluidics (i.e. la ...
12–1 DNA
... If Hershey and Chase could determine which part of the virus entered an infected cell, they would learn whether genes were made of protein or DNA. They grew viruses in cultures containing radioactive isotopes of phosphorus-32 (32P) and ...
... If Hershey and Chase could determine which part of the virus entered an infected cell, they would learn whether genes were made of protein or DNA. They grew viruses in cultures containing radioactive isotopes of phosphorus-32 (32P) and ...
12–1 DNA - Cloudfront.net
... If Hershey and Chase could determine which part of the virus entered an infected cell, they would learn whether genes were made of protein or DNA. They grew viruses in cultures containing radioactive isotopes of phosphorus-32 (32P) and ...
... If Hershey and Chase could determine which part of the virus entered an infected cell, they would learn whether genes were made of protein or DNA. They grew viruses in cultures containing radioactive isotopes of phosphorus-32 (32P) and ...
Nucleic acid hybridisation and polymerase chain reaction
... containing the SP6 promoter. R N A probes are single-stranded (ss) and thus there is no competing reassociation during hybridisation; they are therefore more sensitive than double-stranded (ds) D N A probes (1). If the P C R has been optimised for a particular pathogen, p r o b e s for detection of ...
... containing the SP6 promoter. R N A probes are single-stranded (ss) and thus there is no competing reassociation during hybridisation; they are therefore more sensitive than double-stranded (ds) D N A probes (1). If the P C R has been optimised for a particular pathogen, p r o b e s for detection of ...
DNA - An overview - World of Teaching
... uni - and bidirectional replication. • We now have direct evidence showing that replication in E.coli and several other organisms proceeds bidirectionally from a unique origin. ...
... uni - and bidirectional replication. • We now have direct evidence showing that replication in E.coli and several other organisms proceeds bidirectionally from a unique origin. ...
Innate immune detection of microbial nucleic acids
... other studies demonstrated sequence-specific sensing by TLR13 of 23S rRNA [13,14]. This establishes 23S rRNA as a bona fide PAMP and provides a rare example (to date) of PRR sensing of bacterial, as opposed to viral, RNA. Very interestingly, the RNA sequence recognized by TLR13 is within a region of ...
... other studies demonstrated sequence-specific sensing by TLR13 of 23S rRNA [13,14]. This establishes 23S rRNA as a bona fide PAMP and provides a rare example (to date) of PRR sensing of bacterial, as opposed to viral, RNA. Very interestingly, the RNA sequence recognized by TLR13 is within a region of ...
CHAPTER 27: DNA STRUCTURE, REPLICATION, REPAIR
... E. coli mutants lacking Pol I have normal growth and DNA replication ...
... E. coli mutants lacking Pol I have normal growth and DNA replication ...
Virus Inactivation - Evaluation of Processes used in Biowaste
... thermal and biological treatments such as composting, and disinfection using chemicals such as ammonia. As the high eggshell content of HW could make it unsuitable for composting and anaerobic digestion, liming is often used in Sweden as a chemical method for sanitation. However, this treatment resu ...
... thermal and biological treatments such as composting, and disinfection using chemicals such as ammonia. As the high eggshell content of HW could make it unsuitable for composting and anaerobic digestion, liming is often used in Sweden as a chemical method for sanitation. However, this treatment resu ...
Biosafety Manual - UC Berkeley, EHS
... infection and disease in otherwise healthy adults. Many RG2 agents have been associated with laboratory-acquired infections. The progression from invasion to infection to disease following contact with an infectious agent depends upon the route of transmission, inoculum, invasive characteristics of ...
... infection and disease in otherwise healthy adults. Many RG2 agents have been associated with laboratory-acquired infections. The progression from invasion to infection to disease following contact with an infectious agent depends upon the route of transmission, inoculum, invasive characteristics of ...
video slide - Biology Junction
... • The broadest variety of RNA genomes – Is found among the viruses that infect animals ...
... • The broadest variety of RNA genomes – Is found among the viruses that infect animals ...
DNA virus
A DNA virus is a virus that has DNA as its genetic material and replicates using a DNA-dependent DNA polymerase. The nucleic acid is usually double-stranded DNA (dsDNA) but may also be single-stranded DNA (ssDNA). DNA viruses belong to either Group I or Group II of the Baltimore classification system for viruses. Single-stranded DNA is usually expanded to double-stranded in infected cells. Although Group VII viruses such as hepatitis B contain a DNA genome, they are not considered DNA viruses according to the Baltimore classification, but rather reverse transcribing viruses because they replicate through an RNA intermediate. Notable diseases like smallpox, herpes, and chickenpox are caused by such DNA viruses.