Non-Mendelian Inheritance | Principles of Biology from Nature
... heterozygous Tay-Sachs carriers, the functional allele in carriers produces some enzyme but not as much as homozygous non-carriers make, similar to the way the red allele produces enough red pigment in heterozygous snapdragons to make them pink. Most genes have multiple phenotypic effects. Genes cod ...
... heterozygous Tay-Sachs carriers, the functional allele in carriers produces some enzyme but not as much as homozygous non-carriers make, similar to the way the red allele produces enough red pigment in heterozygous snapdragons to make them pink. Most genes have multiple phenotypic effects. Genes cod ...
reviews
... As more whole-genome sequences become available, it is becoming increasingly important to understand the forces that have shaped their organization. Here, we review the mechanisms that lead to retention versus loss of duplicated genes and consider the broader implications at both a genetic and an ev ...
... As more whole-genome sequences become available, it is becoming increasingly important to understand the forces that have shaped their organization. Here, we review the mechanisms that lead to retention versus loss of duplicated genes and consider the broader implications at both a genetic and an ev ...
Molecular Cytogenetics
... Background: Characterization of disease-associated balanced translocations has led to the discovery of genes responsible for many disorders, including syndromes that include various forms of diabetes mellitus. We studied a man with unexplained maturity onset diabetes of the young (MODY)-like diabete ...
... Background: Characterization of disease-associated balanced translocations has led to the discovery of genes responsible for many disorders, including syndromes that include various forms of diabetes mellitus. We studied a man with unexplained maturity onset diabetes of the young (MODY)-like diabete ...
Praktikum der Microarray-Datenanalyse
... • if H0 is true, no more than a fraction α of the replications will yield a p-value ≤ α • subject-sampling p-value: replications involve taking a new sample of subjects and measure same genes → a significant p-values gives confidence to find the same associations within a new sample of subjects • ge ...
... • if H0 is true, no more than a fraction α of the replications will yield a p-value ≤ α • subject-sampling p-value: replications involve taking a new sample of subjects and measure same genes → a significant p-values gives confidence to find the same associations within a new sample of subjects • ge ...
Analysis of SV - Genome Analysis Wiki
... Mappers will not be able to place reads correctly in the inversion, or across the breakpoints ...
... Mappers will not be able to place reads correctly in the inversion, or across the breakpoints ...
Community Genome Annotation Training
... Checker (GEP website, custom software) is a great tool for catching many annotation errors and eliminating implausible gene models, but does not give students information about the correct model. CGAT database could be used by students after the Gene Model Checker as a training tool (and/or the next ...
... Checker (GEP website, custom software) is a great tool for catching many annotation errors and eliminating implausible gene models, but does not give students information about the correct model. CGAT database could be used by students after the Gene Model Checker as a training tool (and/or the next ...
towards synthetic plant genomes, transcriptomes and epigenomes
... *For correspondence (e-mail [email protected]). ...
... *For correspondence (e-mail [email protected]). ...
Decomposition of DNA Sequence Complexity
... authors have observed [13]. (2) Four-symbol decomposition, allowing one to compare single-base contributions, shows that A and T profiles were generally above the C and G ones (Fig. 3). Note that the overall complexity of the entire genome sequence of E. coli is very similar to that obtained with on ...
... authors have observed [13]. (2) Four-symbol decomposition, allowing one to compare single-base contributions, shows that A and T profiles were generally above the C and G ones (Fig. 3). Note that the overall complexity of the entire genome sequence of E. coli is very similar to that obtained with on ...
Identification of Mga1, a G‐protein α‐subunit gene involved in
... Heterotrimeric G-proteins consist of three subunits: Ga, Gb and Gg. They function as ‘molecular switches’ in G-protein signalling pathways to regulate the duration and intensity of the signal, eventually going on to regulate downstream cell processes. Most characterized filamentous fungi possess thr ...
... Heterotrimeric G-proteins consist of three subunits: Ga, Gb and Gg. They function as ‘molecular switches’ in G-protein signalling pathways to regulate the duration and intensity of the signal, eventually going on to regulate downstream cell processes. Most characterized filamentous fungi possess thr ...
Annotation report - GEP Community Server
... position. For example, the presence of RNA-Seq read coverage upstream of the annotated TSS indicates that the TSS is located further upstream and it would be considered to be evidence against (i.e. Refute) the annotated TSS. In contrast, the lack of RNA-Seq read coverage is a negative result and it ...
... position. For example, the presence of RNA-Seq read coverage upstream of the annotated TSS indicates that the TSS is located further upstream and it would be considered to be evidence against (i.e. Refute) the annotated TSS. In contrast, the lack of RNA-Seq read coverage is a negative result and it ...
The causes and molecular consequences of polyploidy
... lead to reproductive isolation of the newly formed polyploid owing to minority cytotype exclusion.30 A recent study demonstrated that one genetic component of the triploid block in A. thaliana is the paternally expressed gene ADMETOS.31 This study involved a mutant screen in a JASON mutant backgroun ...
... lead to reproductive isolation of the newly formed polyploid owing to minority cytotype exclusion.30 A recent study demonstrated that one genetic component of the triploid block in A. thaliana is the paternally expressed gene ADMETOS.31 This study involved a mutant screen in a JASON mutant backgroun ...
1 Counting 1.1 Orderings
... Another common idea in counting is to divide up the collection into separate cases. In this approach, we count the individual cases separately and then add the answers we get. Example 1.6. Suppose we roll two dice. If the dice are distinguishable, how many outcomes are there? What if the dice are in ...
... Another common idea in counting is to divide up the collection into separate cases. In this approach, we count the individual cases separately and then add the answers we get. Example 1.6. Suppose we roll two dice. If the dice are distinguishable, how many outcomes are there? What if the dice are in ...
Consensus Clustering for Binning Metagenome Sequences
... During the last years, the development of next-generation sequencing technologies allows researchers to sequence multiple genomes of different organisms within an environmental sample. These sequencing methods have the capacity to sequence uncultivable organisms, which have lead a revolution in gene ...
... During the last years, the development of next-generation sequencing technologies allows researchers to sequence multiple genomes of different organisms within an environmental sample. These sequencing methods have the capacity to sequence uncultivable organisms, which have lead a revolution in gene ...
Predicting the Genes Regulated by MicroRNAs via Binding Sites in
... Abstract: MicroRNAs form one of the groups of small noncoding RNA molecules that have completely changed our understanding of gene regulatory networks. Because microRNAs have been discovered only relatively recently, most of their functions remain unknown, providing a challenge to both experiment an ...
... Abstract: MicroRNAs form one of the groups of small noncoding RNA molecules that have completely changed our understanding of gene regulatory networks. Because microRNAs have been discovered only relatively recently, most of their functions remain unknown, providing a challenge to both experiment an ...
Text S1.
... molecular evolution studies of the S-locus in Brassicaceae (e.g. [23]). Hence, these two pairs of sequences are certainly corresponding to four distinct S-alleles present in the common ancestor of both A. halleri and A. lyrata. ...
... molecular evolution studies of the S-locus in Brassicaceae (e.g. [23]). Hence, these two pairs of sequences are certainly corresponding to four distinct S-alleles present in the common ancestor of both A. halleri and A. lyrata. ...
5 Complementation Analysis: How Many Genes are Involved?
... such as a homodimer, or if it encodes a single polypeptide that carries out several distinctfunctions.Inthe case of thehomomultimericprotein, mutant subunits encoded by different mutant genes associate with one another in the multimeric protein and are able to accommodate each other’s mutant alterat ...
... such as a homodimer, or if it encodes a single polypeptide that carries out several distinctfunctions.Inthe case of thehomomultimericprotein, mutant subunits encoded by different mutant genes associate with one another in the multimeric protein and are able to accommodate each other’s mutant alterat ...
Genetic Basis of Coronary Atherosclerosis
... genome-wide SNPs association studies (13). While there is a considerable debate regarding the best approach for genome -wide SNP association studies, candidate gene approach has emerged as the practical approach that could be pursued at multiple levels. Because SNPs do not exist in isolation, compre ...
... genome-wide SNPs association studies (13). While there is a considerable debate regarding the best approach for genome -wide SNP association studies, candidate gene approach has emerged as the practical approach that could be pursued at multiple levels. Because SNPs do not exist in isolation, compre ...
Horizontal transfer of non-LTR retrotransposons: artifact or rare event
... with the origin of a second ORF in front of the RT-encoding ORF. Our knowledge of non-LTR retrotransposon diversity is likely to increase further: almost all studies of the entire genomic sequences detect new phylogenetic groups, especially those which have a limited distribution and/or are represen ...
... with the origin of a second ORF in front of the RT-encoding ORF. Our knowledge of non-LTR retrotransposon diversity is likely to increase further: almost all studies of the entire genomic sequences detect new phylogenetic groups, especially those which have a limited distribution and/or are represen ...
Determinants of pathogenic@ and avirulence in plant pathogenic
... cognate R gene [26,48*,49]. A key question is whether this results from interaction of abnormally high levels of the bacterial protein with plant virulence targets or from interaction with cross-reacting R-gene products. Further evidence suggesting that some avr genes in I! syringae are beneficial t ...
... cognate R gene [26,48*,49]. A key question is whether this results from interaction of abnormally high levels of the bacterial protein with plant virulence targets or from interaction with cross-reacting R-gene products. Further evidence suggesting that some avr genes in I! syringae are beneficial t ...