Potential of promotion of alleles by genome editing for improving
... Overall hypothesis of GS2.0 • Sequence data has huge potential in livestock and plant breeding • Huge volumes of sequence needed to realize ...
... Overall hypothesis of GS2.0 • Sequence data has huge potential in livestock and plant breeding • Huge volumes of sequence needed to realize ...
The hybrid origins of three perennial Medicago species
... lineage arises through the merging of two different parental genomes, without an increase in ploidy level (Buerkle and Rieseberg 2008). For a homoploid hybrid species to be viable, the parental species need to be close relatives so that the merging of chromosomes won’t be problematic. The first gene ...
... lineage arises through the merging of two different parental genomes, without an increase in ploidy level (Buerkle and Rieseberg 2008). For a homoploid hybrid species to be viable, the parental species need to be close relatives so that the merging of chromosomes won’t be problematic. The first gene ...
Functional Annotation
... Bio-ontologies are used to capture biological information in a way that can be read by both humans and computers. necessary for high-throughput “omics” datasets allows data sharing across databases ...
... Bio-ontologies are used to capture biological information in a way that can be read by both humans and computers. necessary for high-throughput “omics” datasets allows data sharing across databases ...
PraderWilli syndrome resulting from an unbalanced translocation
... proband, array CGH and FISH analyses demonstrated an approximate 7 Mb deletion of distal 5p suggesting a mechanism other than affinity to telomeric sequences. Proximal 15q is rich in repeat sequences and duplicons that are involved in the microdeletion seen in PWS, as well as in the formation of chr ...
... proband, array CGH and FISH analyses demonstrated an approximate 7 Mb deletion of distal 5p suggesting a mechanism other than affinity to telomeric sequences. Proximal 15q is rich in repeat sequences and duplicons that are involved in the microdeletion seen in PWS, as well as in the formation of chr ...
- Iranian Journal of Basic Medical Sciences
... spread of MDR strains and so, rapid identification of resistant strains has a special impact on the treatment and control of dissemination of MDR strains in the communities (4, 5). INH is a pro-drug that enters into the bacillus via passive diffusion, changes into an active form by enzyme catalase-p ...
... spread of MDR strains and so, rapid identification of resistant strains has a special impact on the treatment and control of dissemination of MDR strains in the communities (4, 5). INH is a pro-drug that enters into the bacillus via passive diffusion, changes into an active form by enzyme catalase-p ...
Nucleotide sequence changes in the MSX1 and IRF6 genes in
... >350 recognisable Mendelian single gene disorders [4], teratogenic effects and various uncategorised syndromes. The majority of OFC cases (~70%) are considered nonsyndromic (NS-OFC) where the clefts are isolated, i.e. occur without other anomalies. NS-OFC arises as a complex multifactorial trait wit ...
... >350 recognisable Mendelian single gene disorders [4], teratogenic effects and various uncategorised syndromes. The majority of OFC cases (~70%) are considered nonsyndromic (NS-OFC) where the clefts are isolated, i.e. occur without other anomalies. NS-OFC arises as a complex multifactorial trait wit ...
Lluís Millán Ariño GENOMIC DISTRIBUTION AND FUNCTIONAL SPECIFICITY OF
... 3.1. All H1 variants are non-specifically present at gene promoters and are depleted from transcription start sites (TSS) in active genes In our first attempt to elucidate H1 variant distribution in the genome, we tested occupancy in specific loci corresponding to diverse genomic features. Therefore ...
... 3.1. All H1 variants are non-specifically present at gene promoters and are depleted from transcription start sites (TSS) in active genes In our first attempt to elucidate H1 variant distribution in the genome, we tested occupancy in specific loci corresponding to diverse genomic features. Therefore ...
A Tn 10-lacZ-kanR-URA3 Gene Fusion Transposon for Insertion Mutagenesis and Fusion Analysis of Yeast and Bacterial Genes.
... that produces a high, IPTG-inducible level of TnlO transposase function (WAYet al. 1984). pNK629 carries a selectable TetR marker and is compatible with pBR322derived plasmids. Pure preparations of monomeric target DNA were obtained by transforming the target plasmid into a RecA- host such as NK5830 ...
... that produces a high, IPTG-inducible level of TnlO transposase function (WAYet al. 1984). pNK629 carries a selectable TetR marker and is compatible with pBR322derived plasmids. Pure preparations of monomeric target DNA were obtained by transforming the target plasmid into a RecA- host such as NK5830 ...
16S rRNA Sequence Analysis of Bacteria Present in Foaming Activated Sludge Introduction
... reclassified from Rhodococcus maris by RAINEY et al. (1995). D. maris has been isolated as a dominant microbe from activated sludge foam (SEZGIN et al. 1988). In Group 2 clones 14 and 17 grouped with Nostocoida limicola II often associated with foaming activated sludge (SEVIOUR and BLACKALL, 1999). ...
... reclassified from Rhodococcus maris by RAINEY et al. (1995). D. maris has been isolated as a dominant microbe from activated sludge foam (SEZGIN et al. 1988). In Group 2 clones 14 and 17 grouped with Nostocoida limicola II often associated with foaming activated sludge (SEVIOUR and BLACKALL, 1999). ...
Phenotypic overlap in the contribution of individual genes to CNV
... CNV phenotypes. Every phenotype scoring above a similarity threshold is selected to be part of the resulting ‘phenogram’ (described below; see also Quantification of Phenogram Score in the Methods section), and each phenogram is scored according to its IC power sum. An empirical P-value is calculate ...
... CNV phenotypes. Every phenotype scoring above a similarity threshold is selected to be part of the resulting ‘phenogram’ (described below; see also Quantification of Phenogram Score in the Methods section), and each phenogram is scored according to its IC power sum. An empirical P-value is calculate ...
Fungal - CBS-KNAW Fungal Biodiversity Centre
... et al., 2001; Pretorius et al., 2003; Stewart et al., 1999). Based on these data, it is clear that if sexual states do exist for these species, they would reside in Mycosphaerella. In the absence of a known sexual stage, several approaches can be used to test for evidence of sexual reproduction. Pop ...
... et al., 2001; Pretorius et al., 2003; Stewart et al., 1999). Based on these data, it is clear that if sexual states do exist for these species, they would reside in Mycosphaerella. In the absence of a known sexual stage, several approaches can be used to test for evidence of sexual reproduction. Pop ...
PHS 416-1/416-9Continuation (Rev. 10/05), Continuation Format
... because genes for complex behavioral disorders have proven more difficult to find than initially anticipated {Plomin, 2005}. DYX1C1 (or EKN1), which resides in the 15q21 region, was the first candidate gene proposed for RD {Taipale, 2003}. More recently, three new candidate genes have been proposed: ...
... because genes for complex behavioral disorders have proven more difficult to find than initially anticipated {Plomin, 2005}. DYX1C1 (or EKN1), which resides in the 15q21 region, was the first candidate gene proposed for RD {Taipale, 2003}. More recently, three new candidate genes have been proposed: ...
Genomic Analysis of Hox Clusters in the Sea Lamprey
... were aligned with those from mouse and amphioxus. This alignment was then used in a neighbor-joining analysis resulting in the bootstrapped tree of Figure 3. The known mouse Hox gene cognates cluster together on the neighbor-joining tree in all cases. Note that for the posterior (i.e., 5′) cognate g ...
... were aligned with those from mouse and amphioxus. This alignment was then used in a neighbor-joining analysis resulting in the bootstrapped tree of Figure 3. The known mouse Hox gene cognates cluster together on the neighbor-joining tree in all cases. Note that for the posterior (i.e., 5′) cognate g ...
TNFα signals through specialized factories where responsive coding
... small? Does it mean that the vast majority of reads in the 4C -Seq readout are just hits on the same small number of contacts? Does it mean that the library contacts are primarily the high frequency contacts while the additional contacts revealed by the Seq approach are primarily much lower probabil ...
... small? Does it mean that the vast majority of reads in the 4C -Seq readout are just hits on the same small number of contacts? Does it mean that the library contacts are primarily the high frequency contacts while the additional contacts revealed by the Seq approach are primarily much lower probabil ...
CentrosomeDB: a new generation of the
... domains in centrosomal proteins. Along with the 3D structure of the protein and information on the GO, CentrosomeDB users can also find information on the known PPIs. Two levels of interactions have been provided. PPI were given a higher importance in this new version, supporting not only interaction ...
... domains in centrosomal proteins. Along with the 3D structure of the protein and information on the GO, CentrosomeDB users can also find information on the known PPIs. Two levels of interactions have been provided. PPI were given a higher importance in this new version, supporting not only interaction ...
Erp, an extracellular protein family specific to
... paratuberculosis (http :\\www.cbc.umn.edu\cgi-bin\ blasts\AGAC.restrict\blastn.cgi) were released, showing the erp gene to be present in both species, thereby confirming and extending our data. It is thus very likely that erp is common to all members of the genus Mycobacterium. Conservation of the e ...
... paratuberculosis (http :\\www.cbc.umn.edu\cgi-bin\ blasts\AGAC.restrict\blastn.cgi) were released, showing the erp gene to be present in both species, thereby confirming and extending our data. It is thus very likely that erp is common to all members of the genus Mycobacterium. Conservation of the e ...
Fifteen years of genomewide scans for selection: trends, lessons
... over the last 15 years due to increased availability of genome-scale genetic data. Here, we report a representative survey of GWSS from 1999 to present and find that (i) between 1999 and 2009, 35 of 49 (71%) GWSS focused on human, while from 2010 to present, only 38 of 83 (46%) of GWSS focused on hu ...
... over the last 15 years due to increased availability of genome-scale genetic data. Here, we report a representative survey of GWSS from 1999 to present and find that (i) between 1999 and 2009, 35 of 49 (71%) GWSS focused on human, while from 2010 to present, only 38 of 83 (46%) of GWSS focused on hu ...
Endocytobiosis and Cell Research
... Bradyrhizobium japonicum and Sinorhizobium fredii are sensitive towards the phytoalexin glyceollin. The antibacterial effect of the soybean phytoalexin glyceollin was assayed using a liquid microculture technique (Parniske et al., 1991). Log-phase cells of Bradyrhizobium japonicum and Sinorhizobium ...
... Bradyrhizobium japonicum and Sinorhizobium fredii are sensitive towards the phytoalexin glyceollin. The antibacterial effect of the soybean phytoalexin glyceollin was assayed using a liquid microculture technique (Parniske et al., 1991). Log-phase cells of Bradyrhizobium japonicum and Sinorhizobium ...
R i
... • Information theory provides general solutions to the problem of how to recognize members of a group of related nucleic acid (or protein) sequences. ...
... • Information theory provides general solutions to the problem of how to recognize members of a group of related nucleic acid (or protein) sequences. ...
Environmental Pollution
... above-mentioned target genes. This method provided a clone library, and sequencing revealed information on new prokaryotes which grouped mainly next to uncultured microorganisms. However, due to the high diversity of approximately 104 ribotypes (wdifferent bacteria) in soils (Torsvik et al., 1990), ...
... above-mentioned target genes. This method provided a clone library, and sequencing revealed information on new prokaryotes which grouped mainly next to uncultured microorganisms. However, due to the high diversity of approximately 104 ribotypes (wdifferent bacteria) in soils (Torsvik et al., 1990), ...
Mating-Type Genes From the Homothallic Fungus Sordaria
... macrospora genomic DNA and cosmid DNAs revealed that the cloned DNAs are not rearranged with respect to their true genomic organization and that the S. macrospora mating-type genes all have a single copy in the genome (data not shown). The deduced physical map of the genome in the mating-type region ...
... macrospora genomic DNA and cosmid DNAs revealed that the cloned DNAs are not rearranged with respect to their true genomic organization and that the S. macrospora mating-type genes all have a single copy in the genome (data not shown). The deduced physical map of the genome in the mating-type region ...