Towards an accurate identification of mosaic genes and partial
... INTRODUCTION Horizontal gene transfer (HGT) (also called lateral gene transfer) is one of the major mechanisms contributing to microbial genome diversification. HGT is dominant among various groups of genes in prokaryotes (1). The understanding of the key role played by HGT in species evolution has b ...
... INTRODUCTION Horizontal gene transfer (HGT) (also called lateral gene transfer) is one of the major mechanisms contributing to microbial genome diversification. HGT is dominant among various groups of genes in prokaryotes (1). The understanding of the key role played by HGT in species evolution has b ...
QUANTITATIVE TRAITS - QUALITATIVE TRAITS AND
... or intelligence in man; amount of flowers, fruits, seeds, milk, meat or egg produced by plants or animals, etc. The quantitative traits are also called metric traits. They do not show clear cut differences between individuals and forms a spectrum of phenotypes which blend imperceptively from one typ ...
... or intelligence in man; amount of flowers, fruits, seeds, milk, meat or egg produced by plants or animals, etc. The quantitative traits are also called metric traits. They do not show clear cut differences between individuals and forms a spectrum of phenotypes which blend imperceptively from one typ ...
Comparison of Statistical Models for Affymetrix GeneChip
... Model-based estimators are superior to simple averaging Full model superior to reduced this does not necessarily mean that the mismatch probes are a good idea - but if they are present we should use them we have demonstrated this using both analytic considerations and experimental data a carefully d ...
... Model-based estimators are superior to simple averaging Full model superior to reduced this does not necessarily mean that the mismatch probes are a good idea - but if they are present we should use them we have demonstrated this using both analytic considerations and experimental data a carefully d ...
High-resolution haplotype structure in the human genome
... (shown elsewhere in this issue)20. This allows the common variation in a gene to be tested exhaustively for association with disease (given a specified level of genotype relative risk and disease allele frequency). Although this analysis, such as presented in the companion paper1, will not always di ...
... (shown elsewhere in this issue)20. This allows the common variation in a gene to be tested exhaustively for association with disease (given a specified level of genotype relative risk and disease allele frequency). Although this analysis, such as presented in the companion paper1, will not always di ...
Genetic epidemiology: Systemic lupus erythematosus | Arthritis
... haplotype has been associated with SLE in whites and confers a two- to threefold increased risk of SLE [1]. The TNF-α –308A polymorphism is located within the promoter region of the gene and is associated with increased production of TNF-α. This polymorphism is in strong linkage disequilibrium with ...
... haplotype has been associated with SLE in whites and confers a two- to threefold increased risk of SLE [1]. The TNF-α –308A polymorphism is located within the promoter region of the gene and is associated with increased production of TNF-α. This polymorphism is in strong linkage disequilibrium with ...
Analysis of imputed rare variants
... the trait of all rare variants within the functional unit. • Methodology allowing for different directions of effect of rare variants are well established for resequencing data, and are being generalised to allow for imputation. • The most powerful rare variant test will depend on the underlying gen ...
... the trait of all rare variants within the functional unit. • Methodology allowing for different directions of effect of rare variants are well established for resequencing data, and are being generalised to allow for imputation. • The most powerful rare variant test will depend on the underlying gen ...
Mapping quantitative trait loci and expressed sequence tags related
... association with the desired trait. Genetic mapping with markers derived from expressed sequence tags (ESTs) or known genes whose functions are possibly related to the phenotypic traits is an effective method for identifying QTLassociated genes. Using this strategy, expressed sequence tags (ESTs) and ...
... association with the desired trait. Genetic mapping with markers derived from expressed sequence tags (ESTs) or known genes whose functions are possibly related to the phenotypic traits is an effective method for identifying QTLassociated genes. Using this strategy, expressed sequence tags (ESTs) and ...
Significant enhancement of fatty acid composition in seeds of the
... mutations in the FAD2 genes of Arabidopsis and Camelina plants was confirmed by DNA sequencing. Sequence analyses of DNA from leaf and seed samples (Data Set S2) confirmed multiple mutations over multiple generations at each of the three target sites in each of the three different FAD2 gene types pr ...
... mutations in the FAD2 genes of Arabidopsis and Camelina plants was confirmed by DNA sequencing. Sequence analyses of DNA from leaf and seed samples (Data Set S2) confirmed multiple mutations over multiple generations at each of the three target sites in each of the three different FAD2 gene types pr ...
Drosophila Infections in for Resistance to Gram
... Drosophila Diptericin and Attacin are thought to be active on Gram-negative bacteria. In addition to its main anti-Gram-negative activity, Cecropin has been reported to be also active on fungi (7). Defensin is the peptide that displays the major anti-Gram-positive activity in Drosophila (P. Bulet, p ...
... Drosophila Diptericin and Attacin are thought to be active on Gram-negative bacteria. In addition to its main anti-Gram-negative activity, Cecropin has been reported to be also active on fungi (7). Defensin is the peptide that displays the major anti-Gram-positive activity in Drosophila (P. Bulet, p ...
Copy number variations involving the microtubule
... CNVs (copy number variations) are unbalanced structural variations of genomic DNA, such as duplications and deletions. They have originally been defined as ‘segments of at least 1 kb in size, for which copy number differences have been observed in the comparison of two or more genomes’ [1]. With the ...
... CNVs (copy number variations) are unbalanced structural variations of genomic DNA, such as duplications and deletions. They have originally been defined as ‘segments of at least 1 kb in size, for which copy number differences have been observed in the comparison of two or more genomes’ [1]. With the ...
Population Differences in Transcript
... This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. Funding: This research was supp ...
... This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. Funding: This research was supp ...
Evolution of antifreeze glycoprotein gene from a trypsinogen gene in
... member gene encodes a large polyprotein precursor containing multiple AFGP molecules (12, 14). The first AFGP gene characterized is from the Antarctic notothenioid Notothenia coriiceps, and the AFGP polyprotein precursor it encodes contains 46 AFGP molecules (44 AFGP8 and 2 AFGP7 isoforms) linked in ...
... member gene encodes a large polyprotein precursor containing multiple AFGP molecules (12, 14). The first AFGP gene characterized is from the Antarctic notothenioid Notothenia coriiceps, and the AFGP polyprotein precursor it encodes contains 46 AFGP molecules (44 AFGP8 and 2 AFGP7 isoforms) linked in ...
Floral organ identity genes in the orchid
... angiosperms, orchids are unique in their floral patterning, particularly in floral structures and organ identity. The ABCDE model was proposed as a general model to explain flower development in diverse plant groups, however the extent to which this model is applicable to orchids is still unknown. T ...
... angiosperms, orchids are unique in their floral patterning, particularly in floral structures and organ identity. The ABCDE model was proposed as a general model to explain flower development in diverse plant groups, however the extent to which this model is applicable to orchids is still unknown. T ...
Negative regulation of defense responses in Arabidopsis by two
... SA induces redox changes, which appear to regulate the translocation of the NPR1 protein from the cytoplasm to the nucleus (Mou et al., 2003). Increasing evidence indicates that NPR1 functions through its association with TGA transcription factors. NPR1 interacts with various TGA transcription facto ...
... SA induces redox changes, which appear to regulate the translocation of the NPR1 protein from the cytoplasm to the nucleus (Mou et al., 2003). Increasing evidence indicates that NPR1 functions through its association with TGA transcription factors. NPR1 interacts with various TGA transcription facto ...
Is targeted modification of cytokinin regulatory gene activity in Rapid
... Larkin et al. (2007). Sequences were compared to Arabidopsis and other known protein and nucleotide sequences using MEGA5 (Tamura et al., 2007). The phylogenetic relationship between genes was determined using BLAST to identify homologous genes from the sequence data ...
... Larkin et al. (2007). Sequences were compared to Arabidopsis and other known protein and nucleotide sequences using MEGA5 (Tamura et al., 2007). The phylogenetic relationship between genes was determined using BLAST to identify homologous genes from the sequence data ...
Statistical analysis of DNA microarray data
... photodetector voltage, imbalance in total amount of RNA in each sample, difference in uptaking of the dyes, etc. The objective is is to adjust the gene expression values of all genes so that the ones that are not really differentially expressed have similar values across the array(s). ...
... photodetector voltage, imbalance in total amount of RNA in each sample, difference in uptaking of the dyes, etc. The objective is is to adjust the gene expression values of all genes so that the ones that are not really differentially expressed have similar values across the array(s). ...
Identification and characterization of an early gene in the Lymantria
... SK(+) (Stratagene) to generate pDB120. This fragment contains two internal StyI sites (at nucleotide positions 430 and 1018, see Fig. 3). Digestion of pDB120 with StyI, end-filling the overhangs with Sequenase (USB), and religation, resulted in a subclone, pDB162, which contains a truncated form of ...
... SK(+) (Stratagene) to generate pDB120. This fragment contains two internal StyI sites (at nucleotide positions 430 and 1018, see Fig. 3). Digestion of pDB120 with StyI, end-filling the overhangs with Sequenase (USB), and religation, resulted in a subclone, pDB162, which contains a truncated form of ...
The genetic basis of evolutionary change in gene expression levels
... King & Wilson (1975) wrote what was to become an especially influential paper, arguing that comparisons between human and chimpanzee peptide sequences showed too few differences to account for their observed morphological differences, though they actually provided no guidance as to what level of div ...
... King & Wilson (1975) wrote what was to become an especially influential paper, arguing that comparisons between human and chimpanzee peptide sequences showed too few differences to account for their observed morphological differences, though they actually provided no guidance as to what level of div ...
Navigating the NCBI Intructions
... c. With the exception of MT, the chromosomes of the human genome are in pairs. X and Y are a pair. Using this information and the information from your answer to Question 9A, how many pairs of chromosomes are in the human genome? 10. The Breast Cancer Susceptibility gene BRCA1 is on chromosome 17 in ...
... c. With the exception of MT, the chromosomes of the human genome are in pairs. X and Y are a pair. Using this information and the information from your answer to Question 9A, how many pairs of chromosomes are in the human genome? 10. The Breast Cancer Susceptibility gene BRCA1 is on chromosome 17 in ...
PPTX - Bioinformatics.ca
... • Goal is to segment the genome into sub-classes. In each case, the tools identify certain data properties that subsets of the genome. Based on the groupings, the presence of known features (e.g. transcription start regions) is scored to suggest the functional meaning of the classes established. ...
... • Goal is to segment the genome into sub-classes. In each case, the tools identify certain data properties that subsets of the genome. Based on the groupings, the presence of known features (e.g. transcription start regions) is scored to suggest the functional meaning of the classes established. ...
Variable Autosomal and X Divergence Near and Far from Genes
... on both the autosomes and the X chromosome, we evaluated divergence in windows of increasing genetic distance from the nearest gene for ten great ape populations (fig. 1). We found that divergence in putatively neutral regions increased as the distance from genes increased on both the X and the auto ...
... on both the autosomes and the X chromosome, we evaluated divergence in windows of increasing genetic distance from the nearest gene for ten great ape populations (fig. 1). We found that divergence in putatively neutral regions increased as the distance from genes increased on both the X and the auto ...