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3000-13-3d
3000-13-3d

... generation 31,500 • bacterial stocks AFTER generation 20,000 restarted in longterm experiment; some of them evolved citrate metabolism • prior to 20,000: nada ...
Nuclear genome 1
Nuclear genome 1

... Genetic Redundancy • The sizes of many gene families have increased much more in certain organisms. • May account for much of the unexpectedly high genetic complexity of angiosperms ...
Identification of rare cancer driver mutations by network reconstruction
Identification of rare cancer driver mutations by network reconstruction

... • The aim is to find which specific gene and/or mutation is contributing to tumorigenesis in addition to the acknowledged cancer associated gene. Thus, new drug targets may be found. • Exons sequencing for mutations • SNP chip for detecting deletion and amplification • SAGE for expression, for confi ...
Pi kur, 2004
Pi kur, 2004

... speciation in yeasts. Nature 422: 68–72. Frazer, K.A., et al. (2003) Cross-species sequence comparisons: a review of methods and available resources.Genome Res 13: ...
Gene Finding
Gene Finding

... scores exon predicted by multiple predictors. • Used as a starting point for refinement/verification ...
Fernanda Appleton Biology 1615 Research Paper:” The Oxytricha
Fernanda Appleton Biology 1615 Research Paper:” The Oxytricha

... growth, consistent with the observation of amicronucleate Oxytricha species capable of vigorous growth in laboratory conditions. The macronuclear genome inherits considerable diversity from the micronuclear genome, in the form of abundant nucleotide polymorphisms (SNP heterozygosity is ~4.0%). Addit ...
A T C G - National Angus Conference
A T C G - National Angus Conference

... and computing power for analysis than by data generation ...
Week 13
Week 13

... Copy number analysis Reconstruction of extinct species’ genomes Whole transcriptome (poly-A selection) Small RNA analysis (siRNA, snoRNA, lincRNA, etc.) Gene expression profiling for selected target genes Rare cell identification ...
Ensembl - Internet Database Lab.
Ensembl - Internet Database Lab.

... All of data are also available for download ...
Of Genes and Genomes.
Of Genes and Genomes.

... to learn how to use the genomic information in order to look into the future. There is a big opportunity to try to understand what goes on in cancer—because we have reasons to believe that current technology will allow us to discover many genes that have mutated to cause aberrations in growth and di ...
rs8362 and rs6139034 was carried out. The results showed that only
rs8362 and rs6139034 was carried out. The results showed that only

... The present study aims to find any unreported susceptibility genes to young tuberculosis (TB) in the candidate region on chromosome (Chr.) 20 in Thai population. TB is one of the three major infectious diseases worldwide and is known to be a complex disease that both genetic and environmental factor ...
Gene Technology
Gene Technology

...  Summarize the steps involved in making a vaccine  Describe how gene therapy is being used to treat genetic disorders  Identify uses of DNA fingerprinting  Describe the goals of the Human Genome Project ...
Ribosomal MLST - The Maiden Lab
Ribosomal MLST - The Maiden Lab

... The Ribosomal Multi-Locus Sequence Typing (rMLST) database hosted on the PubMLST website provides allelic sequence definitions for more than 3,000 different bacterial species and can be used for rapid speciation and sequence typing across the bacterial domain [1]. The rMLST approach indexes the vari ...
Lecture 25 - life.illinois.edu
Lecture 25 - life.illinois.edu

... 13. What is the "central dogma" of biology? DNA encodes RNA which encodes protein 14. What does "PCR" stand for? How does it work? Polymerase Chain Reaction. It amplifies a single molecule of DNA millions of times. 15. True or false: Transposable elements are very rare in Drosophila melanogaster. 16 ...
Biological databases-Intro
Biological databases-Intro

... available is PubMed. But PubMed has only short abstracts. NO information about conditions, M&M etc We need to change this culture ...
Obtaining the gene of interest: 2 ways: 1. Using a radioactive DNA
Obtaining the gene of interest: 2 ways: 1. Using a radioactive DNA

... giving rise to blood and immune system) are prime candidates. • Success = cells will multiply and express the normal gene, engineered cells will supply the missing protein, patient will be cured. • Ex:Treatment of infants with SCID. But it was halted- they got leukemia symptoms. ...
Gram positive and other bacteria Gram positive bacteria are broken
Gram positive and other bacteria Gram positive bacteria are broken

... B. anthracis-causes anthrax Bt toxin comes from species that produces it to kill larvae Toxin proteins forms crystal that lodges in trachea Clostridium-obligate anaerobes In anaerobic soil conditions Spores can be found in aerobic niches Some human pathogens: tetanus, botulism, gangrene Mollicutes-l ...
Dr. Andrea Bräutigam
Dr. Andrea Bräutigam

... plasmodesmata density, organelle content) and tissue architecture (vein spacing). We hypothesized that a global systemic analysis will reveal the extent of transcriptional regulation of known C4-related genes, identify potential regulators of C4 genes and generate new candidate genes and pathways ne ...
Document
Document

... to the hypothesis that their adaptation to different aphid species is an ongoing process. ...
The majority of genes in the pathogenic Neisseria species are
The majority of genes in the pathogenic Neisseria species are

... in which the two groups adopted fundamentally different approaches that may help to explain the discrepancies observed. Snyder and Saunders employed an intensitybased method that analysed the two channels of a twocolour microarray independently whereas Stabler et al. used a ratio-based method that a ...
What I`ve done this summer
What I`ve done this summer

... GPA, GPB and GPE are highly homologous and form a gene cluster on chromosome 4(q28 - 31). The antigens for the MNS blood group system are GPA and GPB. The existence of about 40 variant phenotypes of this blood group system has been documented by serological analyses. ...
Structural and Functional Genomics of Tomato
Structural and Functional Genomics of Tomato

... create a coordinated network of knowledge about the Solanaceae family ...
슬라이드 1
슬라이드 1

... outcome of infections in different ways that can be either beneficial or detrimental to the host. A function of the multiple copy families, scattered throughout the genome, has been reported regulatory functions on the gene expression of nearby located genes. A small minority of such sequences has a ...
Introduction to your genome
Introduction to your genome

... • If you want to do that, order ASAP, it takes several weeks to get the data back. • Your grade does not depend in any way on whether you analyze your own genome. • You do not need to tell me if you analyze your own genome. • We cannot offer to pay for the test, or provide any counseling ...
Overview of Human Linkage Analysis Terry Speed
Overview of Human Linkage Analysis Terry Speed

... Definition vague, but usually thought of as having multiple, possibly interacting loci, with unknown penetrances; and phenocopies. The terms polygenic and oligogenic are also used, but these do have more specific meanings. There is some evidence that using a range of made-up models can help map gene ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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