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Use of GenoType MTBDR plus assay for the detection of
Use of GenoType MTBDR plus assay for the detection of

... possible by using genetic methods. This paper presents a comparison of drug resistance test results performed by the phenotypic Bactec MGIT 960 and the molecular method using the GenoType MTBDR plus. Results of many studies of comparative tests for GenoType MTBDR plus in relation to conventional met ...
The eukaryotic genome: a system regulated at different hierarchical
The eukaryotic genome: a system regulated at different hierarchical

... identified in a variety of loci (Li et al., 1999; Li et al., 2002). Activation of a genomic domain by such control elements is necessary for activation of individual genes in the cluster but may not be sufficient. The second class of element comprises the enhancers and promoters that decide the acti ...
Genetic analysis of metabolites in apple fruits indicates an mQTL
Genetic analysis of metabolites in apple fruits indicates an mQTL

Two Linked Blood Pressure Quantitative Trait Loci on
Two Linked Blood Pressure Quantitative Trait Loci on

... Figure 1 shows the progenitor strain S.LEW(10) and 5 congenic strains derived from the progenitor strain. This original strain had a 74-cM segment from LEW rats introgressed into the S genetic background and showed a major lowering of BP by ⬇43 mm Hg compared with that of S. This has been reported p ...
Prof. Kamakaka`s Lecture 16 Notes
Prof. Kamakaka`s Lecture 16 Notes

... Catabolite Repression of the lac operonWhen we introduced the subject of regulation of gene expression, I gave an example of the response of E. coli when placed in a media containing both glucose and lactose. The induction of the lac operon does not occur until all the glucose has been metabolized. ...
Strains of Salmonella typhimurium and Other
Strains of Salmonella typhimurium and Other

... The strains of Salmonella typhimurium (official designation, Salmonella enterica serovar Typhimurium) which have been subjected to the most rigorous genetic analysis were originally collected and studied by Lilleengen (36). He tested 703 different strains of S. typhimurium for sensitivity to a set o ...
Casey Gailey 1 Biological Warfare: Preventing a Preplanned Plague
Casey Gailey 1 Biological Warfare: Preventing a Preplanned Plague

... resources quickly in the case of a biological attack. To negate this viable risk, the government should organize various laboratories to remain on call in case of emergencies; so, if there is a plague epidemic and the hospitals involved begin to exhaust their antibiotic supplies, these labs could be ...
Mid-term PowerPoint Presentation
Mid-term PowerPoint Presentation

... The research of Johnston et. al. indicates that E. coli contamination in produce increases during the packaging and processing of cantaloupe, but not in green leafy vegetables. Mubiru et. al. compared the survival rates of pathogenic versus nonpathogenic E. coli and discovered that there is no stati ...
Transgenic Plastids in Basic Research and Plant Biotechnology
Transgenic Plastids in Basic Research and Plant Biotechnology

Evolution of a pseudo-control region in the mitochondrial genome of
Evolution of a pseudo-control region in the mitochondrial genome of

... section between the /RNAG'" and /RNAPh'genes consisting of a 338 bp nonrepetitive section followed by a cluster of 23 tandem repeats with a unit length of 48 bp. Since this noncoding section seems to be the remnant of an ancestral duplicated control region, it was named pseudo-control region (YCR). ...
v2 PEBiosystems News 2 01/00
v2 PEBiosystems News 2 01/00

... sequence was a major scientific accomplishment, but the application of this genomic information to the understanding of biology and disease will have the greatest potential to impact medicine. In this phase of discovery, life science researchers will need the ability to transform the 3.2 Gb of raw s ...
MAK, a computational tool kit for automated MITE
MAK, a computational tool kit for automated MITE

... retrieved (Fig. 1C). False predictions usually result from transposon nesting events and thus can be identified with BLASTN searches. If only the predicted transposase-like regions inside the predicted element are repetitive at the DNA sequence level, such entries are discarded. Since the long eleme ...
Biological interpretation of genome-wide association studies using
Biological interpretation of genome-wide association studies using

... he causal variants, genes and pathways in many genomewide association studies (GWAS) loci often remain elusive, due to linkage disequilibrium (LD) between associated variants, long-range regulation and incomplete biological knowledge of gene function. To translate genetic associations into biologica ...
Genetic evaluation with major genes and polygenic
Genetic evaluation with major genes and polygenic

Genome Biology - Institute for Applied Ecology
Genome Biology - Institute for Applied Ecology

... dosage compensation. A male-specific mechanism means that the male downregulates expression of some genes to match the level of expression in females (Figure 5). This mechanism, by itself, could lower average Z gene expression levels below that of autosomal genes, which conflicts with the observed Z ...
Mapping of the Recessive White Locus and
Mapping of the Recessive White Locus and

Advances in Environmental Biology  Escherichia coli from Frozen Bovine Meat in Algeria
Advances in Environmental Biology Escherichia coli from Frozen Bovine Meat in Algeria

... Some studies show that the presence of the stx2 gene was most of the time associated with the presence of the gene eaeA [37]. Only some studies have shown the presence in the same strain genes stx1, stx2 and eaeA ...
Gene Duplication - Semantic Scholar
Gene Duplication - Semantic Scholar

SNP discovery
SNP discovery

... (1). Third stage filtering: focal points 1 cM intervals across the apple genome, choosing SNPs in 100 kb windows initially based on 712 GDsnp markers (Figure 3) for a total of 842 focal points (2). 6074 SNPs based on focal points + 712 GDsnp + 1652 candidate gene SNPs = 8438 SNPs chosen by this stag ...
Genetic evaluation with major genes and polygenic inheritance
Genetic evaluation with major genes and polygenic inheritance

Analysis of DNA transcription termination sequences of gene coding
Analysis of DNA transcription termination sequences of gene coding

... which has ATPase activity. The second one, called Rhoindependent termination (or intrinsic termination), is related with presence of palindromic sequence that forms a stemloop hairpin structure, which leads to the dissociation of the ternary elongation complex (TEC). Based on recent analysis, only a ...
Uria_et_al_2006 _ADH paper
Uria_et_al_2006 _ADH paper

... Oceans are vast untapped reservoirs of highly diverse and unique natural products accumulated in marine organisms. Enzymes belong to the most interesting natural products from both scientific and industrial perpectives. They are enjoying increasing popularity in the chemical and pharmaceutical indus ...
Gene conversion and purifying selection shape nucleotide variation
Gene conversion and purifying selection shape nucleotide variation

... (Ex3_Rev, Ex5_For and other primers set inside the amplified region). Operationally, we first sequenced the L and M opsin genes of both DNA strands from a sample of a male as only one X-chromosome is present. We sequenced only one strand for other samples if there was no nucleotide difference from t ...
Codon usage bias from tRNA`s point of view
Codon usage bias from tRNA`s point of view

... much more universal trend in the evolution of anticodon and codon choice than previously thought. It also provides new evidence that a selective force for the optimization of the translation machinery is the maximization of growth. [Supplemental material is available online at www.genome.org.] Due t ...
Attack of the Superbugs
Attack of the Superbugs

... treated. However, strains of pneumococcal bacteria resistant to penicillin were discovered in the 1960s. Since then, new strains of pneumococcal bacteria resistant to multiple antibiotics have been emerging. Over the last decade, almost every type of bacteria known to cause disease has become strong ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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