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Control of the acetamidase gene of Mycobacterium smegmatis by
Control of the acetamidase gene of Mycobacterium smegmatis by

... and looked for acetamidase expression under the same conditions as for Mad2. In this case, no induction of the acetamidase was seen. This was not due to deletion of a promoter region as the identi¢ed promoters were all present in the deletion strain [7]. Since amiD is immediately downstream of amiA, ...
Nucleotide sequence analysis - Bioinformatics Unit
Nucleotide sequence analysis - Bioinformatics Unit

... •BLAST  stands  for  Basic  Local  Alignment  Search  Tool.  It  is  used  to  compare  a  novel  sequence  with  those  contained  in  nucleotide  and  protein  databases.  The  emphasis  of  this  tool  is  to  find  regions  of  sequence  similarity.  These  can  yield  clues  about the structure ...
Whole Exome Re-Sequencing Implicates CCDC38 and
Whole Exome Re-Sequencing Implicates CCDC38 and

... Copyright: ß 2014 Wain et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: The whole exome re-sequen ...
Ch. 7: Presentation Slides
Ch. 7: Presentation Slides

... • In spite of the large variation in chromosome number and genome size, there are a number of genetic and physical linkages between single-copy genes that are remarkably conserved in all grasses amid a background of rapidly evolving repetitive DNA • Each of the conserved regions (synteny groups) can ...
Albinism - Harlem Children Society
Albinism - Harlem Children Society

... Albinism is an inherited problem by the imperfection in one or more of the genes responsible for directing the eyes and skin to make melanin. Albinism is mostly a recessively inherited disease which means that you have inherited two albinism genes which causes the development of the disease. ...
Curr. Microbiol. 42
Curr. Microbiol. 42

... thuringiensis standard strains, as well as on 27 B. thuringiensis field isolates, which have previously been found positive to a pair of universal primers (Un7,8 for cry7 and cry8 groups) [2]. Among the standard strains, only B. thuringiensis subsp. dakota HD-511 and B. thuringiensis subsp. kumamoto ...
In vivo evidence for the prokaryotic model of extended codon
In vivo evidence for the prokaryotic model of extended codon

GENES AND DEVELOPMENTAL PATHWAYS
GENES AND DEVELOPMENTAL PATHWAYS

... or polypeptide. It is useful to define the gene in this way since it allows one to retain the widely applicable principle of "one-gene one-enzyme" or "one-gene onepolypeptide." However, it is important to keep in mind that this does not provide an operational definition of the gene. The problem of t ...
Harrisslides
Harrisslides

... • Develop tools: • to query and modify the vocabularies and annotations • annotation tools for curators ...
AtMetExpress Development: A Phytochemical
AtMetExpress Development: A Phytochemical

... (AtMetExpress development) demonstrated that Arabidopsis has the capability of producing diverse metabolites with high tissue specificity. The AtMetExpress development dataset also makes it possible to understand the mechanism behind the variations in metabolic profiles among plant tissues by invest ...
Genome-Wide Gene Expression Effects of Sex Chromosome
Genome-Wide Gene Expression Effects of Sex Chromosome

... and histone modifications established during oogenesis and spermatogenesis (Sha 2008). In mammals, gynogenetic offspring are inviable (McGrath and Solter 1984; Thomson and Solter 1988), indicating that a balanced contribution of chromosomes of paternal and maternal origin is required for development ...
– findings from cross-species Anxiety genetics genome-wide approaches
– findings from cross-species Anxiety genetics genome-wide approaches

... susceptible individuals, and therefore genetic research offers a great route to unravel molecular basis of these diseases. As anxiety is an evolutionarily conserved response, mouse models can be used to carry out genome-wide searches for specific genes in a setting that controls for the environmenta ...
Molecular Mechanisms of Plant and Microbe Coexistence
Molecular Mechanisms of Plant and Microbe Coexistence

... hundreds of microorganisms, mostly bacteria (DeLong 2002). Combinations of new molecular methodology and genomics have been used successfully to link microbial phylogeny with function in several ecological studies and the same approach could provide significant insights into plant–microbe interactio ...
Chapter 1.
Chapter 1.

... Individuals developed from backcrossing or selfing, should have similar genetic backgrounds. Two sister lines, one resistant and the other susceptible are similar to two near-isogenic lines, and can be used as a pair of NILs for screening markers associated with resistance alleles. The advantage of ...
Phenotypic data in FlyBase
Phenotypic data in FlyBase

as a PDF
as a PDF

... (Meyer et al., 1991). However, their capacity to use alternative genetic decoding can be extended to the utilization of ⫹1 frameshifting to express nuclear proteins (Klobutcher and Farabaugh, 2002). It has been estimated that ⬎5% of genes require ⫹1 frameshifting for their expression and although th ...
Test Info Sheet
Test Info Sheet

... dominant, recessive or X-linked dominant traits. The neuroradiologic presentation, age of onset, and accompanying clinical signs are often sufficiently distinct to allow clinical classification of the PCH type and correlate with a molecular diagnosis.1-4 PCH typically manifests as a true Mendelian t ...
Plant Molecular Biology
Plant Molecular Biology

... induced on the inoculated plants. The nucleotide sequence of this gene is presented. On the basis of the sequence a membrane integrated protein is predicted with a molecular weight of 20.1 kDa. Microscopical analysis of the infection process by nodL mutants indicate a role for nodL in maintaining th ...
- eScholarship@UMMS - University of Massachusetts
- eScholarship@UMMS - University of Massachusetts

A global picture of tRNA genes in plant genomes
A global picture of tRNA genes in plant genomes

Genome-Wide Analysis of In Vivo Binding of the Master Regulator
Genome-Wide Analysis of In Vivo Binding of the Master Regulator

... To allow activation and screening of cryptic antibiotic biosynthetic clusters, detailed insight is required into the linkages between environmental (nutritional) signals and secondary metabolite production. Carbon source utilization is a major determining factor in the metabolic control of antibioti ...
HL7 V2.5.1 Genetic Test Result Message
HL7 V2.5.1 Genetic Test Result Message

... Coordinator for Health IT published the Personalized Healthcare Detailed Use Case (Click here to see the use case) in response to a request and specifications from the American Health Information Community. The use case focuses on supporting secure access to electronic genetic laboratory results and ...
Package ‘GenomicFeatures’ October 14, 2014
Package ‘GenomicFeatures’ October 14, 2014

Supplementary Notes S1 (doc 64K)
Supplementary Notes S1 (doc 64K)

... resulted in a final list of 11,000 target chromosomal regions, mostly corresponding to exons. 3. Add flanking sequence to uniform length of 1200 bp in size. Flanking regions were added to all regions less than 600 bp so that their final size will be 1200 bpto accommodate >8 50-60mer probes per regio ...
A Study of Gene Linkage and Mapping Using Tetrad Analysis
A Study of Gene Linkage and Mapping Using Tetrad Analysis

... could use the same approach to develop detailed predictions for the linked model (with genes on opposite or on the same side of the centromere). All models presented here consider only single crossovers. The effect of multiple crossovers and the use of mapping functions and the Poisson distribution ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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