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htr1A - Utrecht University Repository
htr1A - Utrecht University Repository

Supplementary Material for Autozygome Sequencing Expands the
Supplementary Material for Autozygome Sequencing Expands the

... conservation (to detect possible reference genome sequence errors), and the transcriptomic context to detect the presence of alternative splicing and its interaction ...
A Genetic, Deletion, Physical, and Human Homology Map of the
A Genetic, Deletion, Physical, and Human Homology Map of the

... zebrafish and human suggests that the average size of homology segments is on the order of 600 kb (S.L.J. et al., manuscript submitted). In this study, we suggest that the LG2:Hsa1 conserved synteny group in the deletion region is composed of two adjacent homology segments. The order of markers wz45 ...
FocalScan: Scanning for altered genes in cancer based on
FocalScan: Scanning for altered genes in cancer based on

... right). The tile-based analysis scores the genome independently of any reference annotation. It can thus be used to discover potentially interesting changes also in intergenic regions (for instance, relating to novel lncRNAs). For this purpose, by default the genome is divided into 1000 bp overlappi ...
Dragon Genetics
Dragon Genetics

... The Law of Independent Assortment activities help students to understand that genes located on two separate chromosomes are inherited independently. First, the basis for understanding the Law of Independent Assortment is developed by analyzing expected outcomes of meiosis and fertilization. Then, a ...
Identification of Transcription Factors GZF3, RFX1, Orf19.3928 as
Identification of Transcription Factors GZF3, RFX1, Orf19.3928 as

Lecture 11 Beyond Mendel
Lecture 11 Beyond Mendel

... molecules under genetic control. Using genetic analysis one can often detect the patterns of these interactions. For example: • a. In the dihybrid cross AaBb´ x AaBb, nine genotypes will result. If each allelic pair controls a distinct trait and exhibits complete dominance, a 9;3;3;1 phenotypic rati ...
Slide 1
Slide 1

... sequencing small segments of expressed transcripts ("SAGE tags") in such a way that the number of times a SAGE tag sequence is observed is directly proportional to the abundance of the transcript from which it is derived. ...
User_68962022017Bio
User_68962022017Bio

... A chromosome contains alleles for blue eyes and blond hair. After meiosis this original (but modified) chromosome contains alleles for blue eyes and brown hair. This occurred because of Question 4 options: ...
excercise handout
excercise handout

... 17417065 There is a relationship between polymorphisms of the Fyn gene, related to the function of glutamatergic system, and a performance on neuropsychological test of prefrontal cortex activity in schizophrenic patients. ...
DNA Duplications and Deletions Help Determine Health
DNA Duplications and Deletions Help Determine Health

Comparative Genomics
Comparative Genomics

...  Tells us what is common and what is unique between different species at the genome level  The function of human genes and other regions may be revealed by studying their counterparts in lower organisms  Helps identify both coding and non-coding genes and regulatory elements ...
An intron nucleotide sequence variant in a
An intron nucleotide sequence variant in a

... The G->A replacement is not seen in a |5- globin gene isolated from a patient doubly heterozygous for § p° and ^ thalassaemia (N. Moschonas and E. de Boer, personal communication). These data confirm that the intron sequence variant is real and is not due to an artefact in the cloning or sequencing ...
Chelatococcus sambhunathii sp. nov., a moderately thermophilic
Chelatococcus sambhunathii sp. nov., a moderately thermophilic

... subcontinent (Gupta et al., 1975), but the micro-organisms present in these environments have been little studied (but The GenBank/EMBL/DDBJ accession number for the 16S rRNA gene sequence of strain HT4T is DQ322070. A supplementary table detailing the fatty acid composition of strain HT4T and other ...
16S rRNA - Mesa Biological Indicators
16S rRNA - Mesa Biological Indicators

... anomalies. Base differences in the interior of the sequence are more likely to be real differences. In this case, all differences were near both sample ends. Table 2. The concise alignment of the spore crop sample (KAM 1) sequence and the Geobacillus stearothermophilus sequence in the MicroSeq  da ...
J-Express Pro Practicals 2
J-Express Pro Practicals 2

Endogenous Microbial Flora
Endogenous Microbial Flora

... - Humans differ - Most diversity unexplained ...
The white gene
The white gene

... Up until this point, genes have been viewed as a linear array Of indivisible functional units on a chromosome ...
Genes involved in plant stress response and their
Genes involved in plant stress response and their

Memetic Algorithms For Feature Selection On Microarray Data
Memetic Algorithms For Feature Selection On Microarray Data

... wrapper method is how to search the space of feature subsets. On microarray data, as the number of genes (features) are typically very large, most of existing search methods (e.g., complete search, heuristic search, and random search) face the problems of intractable computational time. Genetic Algo ...
The yeast Saccharomyces cerevisiae A model organism in genetics
The yeast Saccharomyces cerevisiae A model organism in genetics

...  In nature, yeast cells always grow as diploids: increases their chance to survive mutation of an essential gene (because there is always a second gene copy).  However, from time to time deleterious mutations need to be ”cleaned out” and advantageous mutations should eventually be manifested.  Un ...
Missing Value Estimation for Gene Expression Profile Data
Missing Value Estimation for Gene Expression Profile Data

The osmZ
The osmZ

Study of lipid metabolism-related genes as candidate
Study of lipid metabolism-related genes as candidate

... There is strong evidence that the onset of puberty is related to growth rate and the amount of body fat. Nellore heifers that are heavier at 12 and 18 months go into first heat at a younger age (Alencar et al., 1987). Recent studies in humans have shown that girls with a relatively higher body mass ...
Davies, Kelli: Eukaryotic Gene Prediction
Davies, Kelli: Eukaryotic Gene Prediction

... discovery. Once genes are identified, further analysis of the coding sequence can be used to identify protein domains to help illuminate function and determine candidates for further study. Homologs in different organisms can be identified via sequence alignment and then further studies can be condu ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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