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The Geographic Distribution of Monoamine Oxidase Haplotypes
The Geographic Distribution of Monoamine Oxidase Haplotypes

... pair for the MAOA gene and 0.007 substitution per intronic base pair for the MAOB gene. The diversity in exonic sequences was similar for the two genes with 0.003 substitution per exonic base pair and 0.004 substitution per exonic base pair for the MAOA and MAOB genes, respectively. To assess the po ...
Detection of Inherited Mutations for Breast and Ovarian
Detection of Inherited Mutations for Breast and Ovarian

"What is a gene, in the post-ENCODE era?"
"What is a gene, in the post-ENCODE era?"

... It was the solution of the three-dimensional structure of DNA by Watson and Crick in 1953 (Watson and Crick 1953) that explained how DNA could function as the molecule of heredity. Base pairing explained how genetic information could be copied, and the existence of two strands explained how occasion ...
Convergent evolution of genes controlling mitonuclear
Convergent evolution of genes controlling mitonuclear

... repeat containing), that control stability of mitochondrial RNAs (Sasarman, et al. 2010), were positively selected in PR-branch. Three proteins annotated as mitochondrial ribosome (MRPs) were under positive selection in each of the two branches (GO:0005761, fold enrichment= 9.1 and 14.7, respectivel ...
What is a gene, post-ENCODE? History and updated definition
What is a gene, post-ENCODE? History and updated definition

... It was the solution of the three-dimensional structure of DNA by Watson and Crick in 1953 (Watson and Crick 1953) that explained how DNA could function as the molecule of heredity. Base pairing explained how genetic information could be copied, and the existence of two strands explained how occasion ...
Lecture: Genome-Wide Association Studies (GWAS)
Lecture: Genome-Wide Association Studies (GWAS)

... Aim 3. To perform second stage of confirmatory association tests between lung cancer risk and more than 500 SNPs that were replicated in Aim 2 among an additional 600 cases and 600 controls. Additional SNPs will also be added from our ongoing pathway specific analyses of DNA repair, cell cycle regul ...
CHAPTER 2 Genome Sequence Acquisition and
CHAPTER 2 Genome Sequence Acquisition and

... It is unlikely that a cytoplasmic structural protein such as dystrophin also regulates transcription. However, there is evidence that muscular dystrophy has a signaling component, and it might be possible that the dystrophin gene produces truncated proteins that might be functional DNA binding prote ...
2014-2015 Internship descriptions
2014-2015 Internship descriptions

... Right now we are interested in assembling reporter gene constructs and tranforming them into plants. This will allow us to monitor transcription in every single cell using the RNA binding protein of the MS2 system. DNA constructs will be assembled using a custom modular cloning system that has been ...
What is a gene, post-ENCODE? History and updated
What is a gene, post-ENCODE? History and updated

... It was the solution of the three-dimensional structure of DNA by Watson and Crick in 1953 (Watson and Crick 1953) that explained how DNA could function as the molecule of heredity. Base pairing explained how genetic information could be copied, and the existence of two strands explained how occasion ...
Chromatin signature reveals over a thousand highly conserved
Chromatin signature reveals over a thousand highly conserved

... Although there are some well-characterized examples, most (.95%) show little evidence of evolutionary conservation and have been suggested to represent transcriptional noise5,6. Here we report a new approach to identifying large non-coding RNAs using chromatin-state maps to discover discrete transcr ...
2 - GEP Community Server
2 - GEP Community Server

... 2. An initial report describing the annotation of one gene found in each student’s data set is required on Feb. 4. This is worth 10 points. 3. The complete annotation report is due on March 4. This is worth 28points. 4. The simulations report is due on March 25. This is worth 10 points. 5. The compl ...
Codon Bias
Codon Bias

... equal proportions. However, this is not the case for many species. For example, analysis of genes in E. coli shows that some valine codons are used more frequently than others are. The GUU codon is used in 25%, GUC is used in 21%, GUA is used in 15%, and GUG is used in 38% of the time. This phenomen ...
Identification and Characterization of a Novel Human Testis
Identification and Characterization of a Novel Human Testis

... tentatively named TSKS (for testis-specific kinase substrate; GenBank Accession No. AF200923). This gene is located closed to RRAS and the human IRF3 gene. On homology analysis, the human TSKS gene was found to be similar to the Mus musculus tssk1 and tssk2 substrate (tssks) gene, described by Kueng ...
Genes
Genes

... small effect ...
Antibiotic Resistance - Colorado State University
Antibiotic Resistance - Colorado State University

Access to the Maize Genome: An Integrated Physical and Genetic Map
Access to the Maize Genome: An Integrated Physical and Genetic Map

BSc in Applied Biotechnology 3 BO0048 ‑ GENETICS PROGRAM
BSc in Applied Biotechnology 3 BO0048 ‑ GENETICS PROGRAM

... • The amount of melanin developing in an individual is determined by two pairs of genes. • There are genes present at two different loci and each dominant gene is responsible for the synthesis of fixed amount of melanin. • The effect of all the genes is addittive and the amount of melanin produced i ...
Presentation
Presentation

... – Copy and paste sequence into text entry box – Await search or analysis on remote database – Get an isolated report that the user must ...
Monohybrid cross
Monohybrid cross

... • This workforce solution was funded by a grant awarded under the President’s Community-Based Job Training Grants as implemented by the U.S. Department of Labor’s Employment and Training Administration. The solution was created by the grantee and does not necessarily reflect the official position of ...
Analyzing stochastic transcription to elucidate the nucleoid`s
Analyzing stochastic transcription to elucidate the nucleoid`s

... view. It might confirm, confute or add new hypotheses. Indeed, since their arrival at the end of the 1980s [5,6], microarrays have been used to explore the chromosomal organization at a small scale (DNA stretches tens to hundreds of bps long) or large scale (thousands of bps long) ...
The genome-scale interplay amongst xenogene silencing
The genome-scale interplay amongst xenogene silencing

... We had previously constructed a double Δhns-stpA deletion mutant in E. coli K12 MG1655 using homologous recombination (6). The transcriptome of this strain––relative to the wild type––during mid-exponential phase in LB medium exhibits an increase in the expression of many A+T-rich genes, consistent ...
NARRATOR: Pembrey was stunned. Angelman syndrome and
NARRATOR: Pembrey was stunned. Angelman syndrome and

... The difference was striking. Less nurtured rats had multiple epigenetic marks silencing the gene. The result? With the gene less active, stress levels in neglected rats soared. In stark contrast, nurtured rats could better handle stress because they had nothing dimming the genes' activity. MOSHE SZY ...
TaWRKY70 transcription factor in wheat QTL-2DL regulates
TaWRKY70 transcription factor in wheat QTL-2DL regulates

... resistant cultivars is considered to be the most efficient, economic and environmental friendly method1. More than 200 QTL have been identified, including a total of 52 QTL associated with rachis resistance based on single floret inoculation2. Among these, the QTL-2DL is one of the major and the mos ...
Document
Document

... If the A to d distance is small, then most chromosomes that carry D also carry A1 Not vice versa (most chromosomes with A1 need not carry D)! Linkage disequilibrium) – nonrandom association of alleles in linked loci – founder effect. Decreases over time. ...
7.1 Chromosomes and Phenotype
7.1 Chromosomes and Phenotype

... • Female mammals have an XX genotype. – Expression of sex-linked genes is similar to autosomal genes in females. – X chromosome inactivation randomly “turns off” one X ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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