alternatively-spliced protein sequences derived
... only be verified using information already present in SWISS-PROT. The results of similarity searches performed against a protein database (using algorithms such as FASTA and BLAST) will clearly be affected by the choice of the isoform whose sequence is displayed for each protein in the database. Imp ...
... only be verified using information already present in SWISS-PROT. The results of similarity searches performed against a protein database (using algorithms such as FASTA and BLAST) will clearly be affected by the choice of the isoform whose sequence is displayed for each protein in the database. Imp ...
IOSR Journal of Computer Engineering (IOSR-JCE)
... Small data sets are used for results. W. Haiying, et al [7], addresses two algorithms self-organizing map and hierarchical clustering for SAGE (Serial Analysis of Gene Expression) data analysis. SOM perform pattern discovery and visualization for SAGE data in a more effective way. Estimation of opti ...
... Small data sets are used for results. W. Haiying, et al [7], addresses two algorithms self-organizing map and hierarchical clustering for SAGE (Serial Analysis of Gene Expression) data analysis. SOM perform pattern discovery and visualization for SAGE data in a more effective way. Estimation of opti ...
Candidate gene prioritization with Endeavour
... estimate actual performance (because leakage of information across multiple sources can lead to overly optimistic results), and time-stamped strategies are often preferable (25). We have therefore defined a time-stamped benchmark that resembles the CAFA strategy (10). The principle is that predictio ...
... estimate actual performance (because leakage of information across multiple sources can lead to overly optimistic results), and time-stamped strategies are often preferable (25). We have therefore defined a time-stamped benchmark that resembles the CAFA strategy (10). The principle is that predictio ...
Extreme Evolution
... Victoria had mutation rates several times higher than the tilapia’s. Many of the affected genes are known to be involved in jaw development, which makes sense, given the range of dietary adaptations seen in cichlids. Thus, one mechanism that has hastened cichlid speciation is intense selection press ...
... Victoria had mutation rates several times higher than the tilapia’s. Many of the affected genes are known to be involved in jaw development, which makes sense, given the range of dietary adaptations seen in cichlids. Thus, one mechanism that has hastened cichlid speciation is intense selection press ...
Chapter 1 - Bioinformatics Research Center
... situ hybridization (and, where an antibody exists, Western blots and immunohistochemistry). Genomic methods rely more on detecting a tag corresponding to each gene in a library of hundreds of thousands of sequenced fragments. EST sequencing, as well as methods such as SAGE and differential display, ...
... situ hybridization (and, where an antibody exists, Western blots and immunohistochemistry). Genomic methods rely more on detecting a tag corresponding to each gene in a library of hundreds of thousands of sequenced fragments. EST sequencing, as well as methods such as SAGE and differential display, ...
Notes S1 Simple sequence repeats and transposable elements
... constraint that may be expected in regions less directly involved in the regulation of gene expression. A similar lack of constraint is exemplified by the dominance of tetranucleotides detected in introns of the H. irregulare genome. 1.2. Transposable element identification and characterization Repe ...
... constraint that may be expected in regions less directly involved in the regulation of gene expression. A similar lack of constraint is exemplified by the dominance of tetranucleotides detected in introns of the H. irregulare genome. 1.2. Transposable element identification and characterization Repe ...
Gene duplications in prokaryotes can be
... example energy production, cell motility, ion transport, and defence mechanisms. A statistical overrepresentation analysis of gene and protein annotations was based on paralogs of the 200 prokaryotes with the highest fraction of paralog-forming genes. Biclustering of overrepresented gene ontology te ...
... example energy production, cell motility, ion transport, and defence mechanisms. A statistical overrepresentation analysis of gene and protein annotations was based on paralogs of the 200 prokaryotes with the highest fraction of paralog-forming genes. Biclustering of overrepresented gene ontology te ...
Ancient Ciphers: Minireview Translation in
... ribosomal protein genes of S. acidocaldarius, it has been suggested that the Shine-Dalgarno sequence overlaps with the GUG initiation codon rather than preceding it by the standard distance of 3 to 10 nt. It is difficult to imagine how this region of the mRNA could interact simultaneously with both ...
... ribosomal protein genes of S. acidocaldarius, it has been suggested that the Shine-Dalgarno sequence overlaps with the GUG initiation codon rather than preceding it by the standard distance of 3 to 10 nt. It is difficult to imagine how this region of the mRNA could interact simultaneously with both ...
![2610//16 1 Allele-specific expression, ASE [1] Defini8on of allele](http://s1.studyres.com/store/data/006248723_1-82195dc62ecf1cc4d0499f4ecaf3249f-300x300.png)
2610//16 1 Allele-specific expression, ASE [1] Defini8on of allele
... • feat: FeatureID as specified in the input file (typically a gene idenBfier) • n.vars: Number of variants within the gene • mean.s: Mean of s across the variants within the gene • median.s: Median of s across the variants within the gene • sd.s: Standard deviaBon of s across the variants with ...
... • feat: FeatureID as specified in the input file (typically a gene idenBfier) • n.vars: Number of variants within the gene • mean.s: Mean of s across the variants within the gene • median.s: Median of s across the variants within the gene • sd.s: Standard deviaBon of s across the variants with ...
GENETIC ENGINEERING
... and is required in order for glucose to pass from'the blood stream into celts which require it for respiration. Until recently, INSULIN obtained from pigs and cattle pancreases was injected into diabetics daily. The supply had been decreasing. An unfortunate side-effect is an allergic reaction. Thos ...
... and is required in order for glucose to pass from'the blood stream into celts which require it for respiration. Until recently, INSULIN obtained from pigs and cattle pancreases was injected into diabetics daily. The supply had been decreasing. An unfortunate side-effect is an allergic reaction. Thos ...
USB® Thermo Sequenase Cycle Sequencing Kit
... This kit and all enclosed reagents should be stored frozen at -20°C (NOT in a frostfree freezer). Keep all reagents on ice when removed from storage for use. The kit can conveniently be stored at +4°C for periods of up to 3 months with no loss of performance, but this should be avoided if it is expe ...
... This kit and all enclosed reagents should be stored frozen at -20°C (NOT in a frostfree freezer). Keep all reagents on ice when removed from storage for use. The kit can conveniently be stored at +4°C for periods of up to 3 months with no loss of performance, but this should be avoided if it is expe ...
MSWord
... Coinertia analysis has been applied to the cross-platform comparison (meta-analysis) of microarray gene expression datasets (Culhane et al., 2003). CIA is a multivariate method that identifies trends or co-relationships in multiple datasets which contain the same samples. That is either the rows or ...
... Coinertia analysis has been applied to the cross-platform comparison (meta-analysis) of microarray gene expression datasets (Culhane et al., 2003). CIA is a multivariate method that identifies trends or co-relationships in multiple datasets which contain the same samples. That is either the rows or ...
Molecular studies on an ancient gene encoding
... Eukaryotic genes, as well as a small number of prokaryotic and organellar genes, have long intervening unexpressed sequences (introns) dividing the coding sequence into pieces (exons). The existence of introns in contemporary genomes has led to several mechanistic and historical questions. The debat ...
... Eukaryotic genes, as well as a small number of prokaryotic and organellar genes, have long intervening unexpressed sequences (introns) dividing the coding sequence into pieces (exons). The existence of introns in contemporary genomes has led to several mechanistic and historical questions. The debat ...
Supplemental Table 11
... in elevated rpd for silent sites relative to neutral expectations (AKASHI 1995, 1999). This can lead ...
... in elevated rpd for silent sites relative to neutral expectations (AKASHI 1995, 1999). This can lead ...
Supplementary Information (doc 62K)
... The first version of the microarray contained 461 DNA hybridization probes targeting microorganisms and 164 positive (16S conserved regions) and negative controls. The probes (approximately 20 base pairs targeting 16S or 18S rRNA gene sequences unique for certain species or higher taxonomic levels, ...
... The first version of the microarray contained 461 DNA hybridization probes targeting microorganisms and 164 positive (16S conserved regions) and negative controls. The probes (approximately 20 base pairs targeting 16S or 18S rRNA gene sequences unique for certain species or higher taxonomic levels, ...
Identification of large-scale human-specific copy number
... studies and our findings suggest that this degree of conservation may extend to the sub-microscopic level. Of the 322 CND sites identified, 14 human lineage-specific gains were observed. Most of these human-specific copy number gains span regions previously identified as segmental duplications (SDs) and ...
... studies and our findings suggest that this degree of conservation may extend to the sub-microscopic level. Of the 322 CND sites identified, 14 human lineage-specific gains were observed. Most of these human-specific copy number gains span regions previously identified as segmental duplications (SDs) and ...
Statistical analysis of DNA microarray data
... not in cell function and proliferation. These genes will be similarly expressed in all samples but they may be difficult to identify – need to be confirmed. Affymetrix GeneChip provides a set of house keeping genes (but still no guarantee). ...
... not in cell function and proliferation. These genes will be similarly expressed in all samples but they may be difficult to identify – need to be confirmed. Affymetrix GeneChip provides a set of house keeping genes (but still no guarantee). ...
Ensembl gene annotation project (e!74
... supported by biological sequence evidence (see the “Supporting evidence” link on the left-hand menu of a Gene page or Transcript page); ab initio models are not included in our gene set. Ab initio predictions and the full set of cDNA and EST alignments to the genome are available on our website. ...
... supported by biological sequence evidence (see the “Supporting evidence” link on the left-hand menu of a Gene page or Transcript page); ab initio models are not included in our gene set. Ab initio predictions and the full set of cDNA and EST alignments to the genome are available on our website. ...
Notes Packet - Ms. Ottolini`s Biology Wiki!
... F. DNA fingerprints can also be used in medicine to determine if a person has a DNA banding pattern characteristic of a genetic (inherited) disease like cystic fibrosis, sickle cell disease, etc. G. DNA fingerprints can also be used to compare DNA samples from different species. 8. Other methods can ...
... F. DNA fingerprints can also be used in medicine to determine if a person has a DNA banding pattern characteristic of a genetic (inherited) disease like cystic fibrosis, sickle cell disease, etc. G. DNA fingerprints can also be used to compare DNA samples from different species. 8. Other methods can ...
A simple set of rules for primer sequence design is as follows
... For example, there is a ¼ chance of finding an A, G, C or T in any given DNA sequence; there is a 1/16 chance of finding any dinucleotide sequence (eg. AG); a 1/256 chance of finding a given 4-base sequence. So, a sixteen base sequence will statistically be present only once in every 4,294,967,296 b ...
... For example, there is a ¼ chance of finding an A, G, C or T in any given DNA sequence; there is a 1/16 chance of finding any dinucleotide sequence (eg. AG); a 1/256 chance of finding a given 4-base sequence. So, a sixteen base sequence will statistically be present only once in every 4,294,967,296 b ...
human gene testing - National Academy of Sciences
... copies of the selected DNA with their own DNA each time they divided. Because a single bacterium grows rapidly, producing more than 1 billion copies of itself in 15 hours, large quantities of a specific DNA sequence can be produced in this manner—called cloning. This DNA can either be used for furth ...
... copies of the selected DNA with their own DNA each time they divided. Because a single bacterium grows rapidly, producing more than 1 billion copies of itself in 15 hours, large quantities of a specific DNA sequence can be produced in this manner—called cloning. This DNA can either be used for furth ...
Functional genomics and gene chips
... possible bases. Alternatively, the presence of a consensus sequence can be tested using one or two probes representing specific alleles. To genotype heterozygous or genetically mixed samples, arrays with many probes can be created to provide redundant information, resulting in unequivocal genotyping ...
... possible bases. Alternatively, the presence of a consensus sequence can be tested using one or two probes representing specific alleles. To genotype heterozygous or genetically mixed samples, arrays with many probes can be created to provide redundant information, resulting in unequivocal genotyping ...
Gene testing - Margie Patlak
... copies of the selected DNA with their own DNA each time they divided. Because a single bacterium grows rapidly, producing more than 1 billion copies of itself in 15 hours, large quantities of a specific DNA sequence can be produced in this manner—called cloning. This DNA can either be used for furth ...
... copies of the selected DNA with their own DNA each time they divided. Because a single bacterium grows rapidly, producing more than 1 billion copies of itself in 15 hours, large quantities of a specific DNA sequence can be produced in this manner—called cloning. This DNA can either be used for furth ...
Biometrics 59, 822-828 December 2003 M. Kathleen Kerr
... Do we want to make inferences about differences in gene expression across AML subpopulations? Or, do we want to make inferences about differences in gene expression in two particular AML patients, each of whom has a different type of AML? ...
... Do we want to make inferences about differences in gene expression across AML subpopulations? Or, do we want to make inferences about differences in gene expression in two particular AML patients, each of whom has a different type of AML? ...
Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Recent studies use either ""shotgun"" or PCR directed sequencing to get largely unbiased samples of all genes from all the members of the sampled communities. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale and detail than before.