• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Disruption of Individual Members of Arabidopsis Syntaxin Gene
Disruption of Individual Members of Arabidopsis Syntaxin Gene

Your Genes, Your Choices
Your Genes, Your Choices

... is not albino. If it is, he and his wife could choose to have an abortion and try again. What do you think of this choice? Adoption is another choice Martin and his wife could make, instead of risking bearing children who are albino. With adoption, the children would not be their own, genetically. B ...
Chapter 13: Genetic Technology
Chapter 13: Genetic Technology

... across both strands. These are called blunt ends. Other enzymes, such as the enzyme called EcoRI, cut palindromic sequences of DNA by unzipping them for a few nucleotides, as shown in Figure 13.4. When this DNA is cut, double-stranded fragments with single-stranded ends are formed. The single-strand ...
Binding of ColEl-kan Plasmid DNA by Tobacco
Binding of ColEl-kan Plasmid DNA by Tobacco

... DNA that was partially degraded by nucleases. Complete integrity of the plasmid DNA would not be required for maintenance of the kanamycin resistance gene if that DNA segment was integrated into the plant cell genome. Third, molecular barriers at the transcription or translation levels may exist whi ...
Genetics Notes - Cobb Learning
Genetics Notes - Cobb Learning

... Mendel’s cross between tall pea plants yielded all tall pea plants. His cross between small pea plants yielded all small pea plants. ...
Tutorial - Ensembl
Tutorial - Ensembl

... the live-site, search for ‘human EPO gene’ and click on the Ensembl gene identifier (ENSG0000130427)- this will link you to the ‘GeneView’ page for the Erythropoeitin precursor. Please note that since this tutorial was constructed updates may have been made, so to emulate this tutorial exactly, plea ...
The Concept of the Gene in Development and Evolution
The Concept of the Gene in Development and Evolution

... cases in which polypeptides are very different, an indicator of functional divergence, some authors recommend subdividing a site of expression into separate genes (Alberts et al. 1994). How different do the polypeptides have to be to split the locus into more than one gene? Molecular biologists do n ...
Nucleotide Sequence and Organization of the Rat Heme Oxygenase
Nucleotide Sequence and Organization of the Rat Heme Oxygenase

... contains a sequence with an imperfect dyad symmetry, GGGTGCTGCACTC (nucleotide residues -581 to -569), which contains two copies of core sequences of metal regulatory elements found in metallothionein genes (34). However, the heme oxygenase gene contains no heme-responsive element of the yeast iso-1 ...
Investigation of the premelanosome protein
Investigation of the premelanosome protein

... cuniculus) has been the objective of pioneering studies on coat colour genetics. However, despite the early role of this species in defining genetic mechanisms determining this phenotypic trait, only recently a few loci have been characterized at the molecular level analysing also in rabbits genes a ...
The Big Picture: an outline of the concepts covered to date
The Big Picture: an outline of the concepts covered to date

... On average ~60 crossovers in paternal genome Recombination is 1.7x more frequent in females than males ~100 out of ~160 Crossovers were at hotspots of recombination ...
Chapter 2 – Alleles at a Single Locus
Chapter 2 – Alleles at a Single Locus

Accepted version  - Queen Mary University of London
Accepted version - Queen Mary University of London

... Benznidazole is the front-line drug used against Trypanosoma cruzi, the causative agent of Chagas disease. This pro-drug is activated within the parasite by a mitochondrial type I nitroreductase. Loss or disruption of a single copy of the gene encoding this flavoprotein is sufficient to cause resist ...
Module 4: The Role of Genes in Cancer
Module 4: The Role of Genes in Cancer

... When a mutation occurs in reproductive cells (a man’s sperm or a woman’s egg cells), then the faulty gene can be passed onto children. This would be an example of an inherited mutation.9 When inherited mutations occur, the mutation will be in all of the offspring's body cells. The fact that every ce ...
Embryo Genome Profiling by Single-Cell
Embryo Genome Profiling by Single-Cell

... indication for PGD as well. Hence, genome-wide profiling of embryos with diagnosis of single gene disorders, HLA matching, sex, and aneuploidy provides an approach to PGD for mendelian disorder carriers, such as the carriers of ␤-thalassemia. Traditionally, multiplex PCR has been used to detect the ...
Scholarship Biology (93101) 2014
Scholarship Biology (93101) 2014

... Giant weta are usually observed alone, or else with a single male close by a female; the male is thought to be attracted to the female by pheromones. It is not clear if stridulatory sounds are important in giant weta mating. D. mahoenui have been seen mating during the day on a gorse bush, tightly l ...
Ku Binds Telomeric DNA in Vitro - Titia de Lange Lab
Ku Binds Telomeric DNA in Vitro - Titia de Lange Lab

CpG Mutation Rates in the Human Genome Are
CpG Mutation Rates in the Human Genome Are

... whose sequences had more than one polymorphic position or more than two possible bases at the polymorphic position. A total of 23,208 human SNPs passed all of these tests and, thus, had an unambiguously orthologous sequence in Pan troglodytes. We chose to discard repetitive sequences because it woul ...
2014 Personalized Medicine Module Presentation
2014 Personalized Medicine Module Presentation

... nucleotides that encode for many genes. Gene RNA: A single-stranded copy of one gene. RNA Protein: Proteins are composed amino acids. Amino acids are made from triplets of nucleotides called codons. ...
Example - Hivebench
Example - Hivebench

Array Flip Book
Array Flip Book

... genetic material across the entire human genome (with the exception of centromeres, telomeres, and satellites) • GenomeDx uses a new technology called ‘Oligonucleotide Array Comparative Genomic Hybridization,’ for short ‘Oligo aCGH’ • Oligo array is a test in which a patient’s DNA and control DNA ar ...
Studies on Chlamydomonas Chloroplast Transformation: Foreign
Studies on Chlamydomonas Chloroplast Transformation: Foreign

... Taken together, the availability of chloroplast DNA mutants, the ability to correct stably deletions in the C. reinhardtii chloroplast genome with introduced homologous DNA, and the high degree of DNA sequence homology to the chloroplast genomes of higher plants suggest that this organism may be wel ...
Display gene network using Data Step Graphics Interface (DSGI)
Display gene network using Data Step Graphics Interface (DSGI)

... Figure 1, an example of gene network data. 2.2 Generate two SAS datasets: gene_list and correlation_list SAS datastep was first applied to generate two SAS datasets according to the preceding gene network data. One dataset “gene_list” contained gene symbols and the known/unknown function information ...
Complete Sequence of the Mitochondrial DNA of
Complete Sequence of the Mitochondrial DNA of

... 4L]). In addition, metazoan mtDNA usually contains at least one lengthy noncoding sequence which regulates and initiates mtDNA replication and transcription (control region; Wolstenholme 1992). In coelomate animals, mitochondrial gene arrangements are generally conserved within each phylum. For exam ...
The complete nucleotide sequence of the chick a
The complete nucleotide sequence of the chick a

... t h i s heating step s u b s t a n t i a l l y improved the resolution of individual bands over background in the sequence l a d d e r . ...
Using comparative genomic hybridization to
Using comparative genomic hybridization to

... (10-15 MY diverged relative to D. melanogaster)[28] provides us with a unique opportunity to demonstrate the degree to which hybridization ratio reflects underlying sequence divergence. It is not our goal to devise an explicit model to explain variation in hybridization due to other sequence charact ...
< 1 ... 77 78 79 80 81 82 83 84 85 ... 445 >

Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report