clinchem.org - Clinical Chemistry
... some 15q11.2– q13 (3, 4 ). Approximately 70% of PWS cases are associated with a de novo paternally derived deletion, ⬃25% with maternal uniparental disomy 15, and the rest with deletions or epimutations in the imprinting center or from chromosome 15q translocations (5–7 ). Duchenne muscular dystroph ...
... some 15q11.2– q13 (3, 4 ). Approximately 70% of PWS cases are associated with a de novo paternally derived deletion, ⬃25% with maternal uniparental disomy 15, and the rest with deletions or epimutations in the imprinting center or from chromosome 15q translocations (5–7 ). Duchenne muscular dystroph ...
transposon
... Transposition in maize was discovered because of the effects of the chromosome breaks generated by transposition of "controlling elements". The break generates one chromosome that has a centromere and a broken end and one acentric fragment. The acentric fragment is lost during mitosis, and thi ...
... Transposition in maize was discovered because of the effects of the chromosome breaks generated by transposition of "controlling elements". The break generates one chromosome that has a centromere and a broken end and one acentric fragment. The acentric fragment is lost during mitosis, and thi ...
Sleeping Beauty - Weber State University
... Accordingly, a series of constructs was made to bring the coding sequence closer, step-by-step, to the consensus using PCR mutagenesis (SB4-SB10 in Figure 1B). As a general approach, the sequence information predicted by the majority-rule consensus was followed. However, at some codons deamination o ...
... Accordingly, a series of constructs was made to bring the coding sequence closer, step-by-step, to the consensus using PCR mutagenesis (SB4-SB10 in Figure 1B). As a general approach, the sequence information predicted by the majority-rule consensus was followed. However, at some codons deamination o ...
The Advantage and Application of Genetically Humanized Mouse
... or tissue-specific transgene expression and inserted randomly into the genome. Alternatively, cDNA containing the human transgene and small promoter fragment can be targeted to a specific location within the genome. Since cDNA constructs lack the non-coding and regulatory elements found in genomic D ...
... or tissue-specific transgene expression and inserted randomly into the genome. Alternatively, cDNA containing the human transgene and small promoter fragment can be targeted to a specific location within the genome. Since cDNA constructs lack the non-coding and regulatory elements found in genomic D ...
Blue eye color in humans may be caused by a perfectly associated
... quently, several other linkage and association studies conWrmed the locus and OCA2 as the major contributors to human eye color variation (Sturm et al. 2001; Zhu et al. 2004; Posthuma et al. 2006; Frudakis et al. 2003) and 74% of the variation was estimated to a QTL, linked to OCA2 (DuVy et al. 2007 ...
... quently, several other linkage and association studies conWrmed the locus and OCA2 as the major contributors to human eye color variation (Sturm et al. 2001; Zhu et al. 2004; Posthuma et al. 2006; Frudakis et al. 2003) and 74% of the variation was estimated to a QTL, linked to OCA2 (DuVy et al. 2007 ...
Functional analysis of the ABCs of eye color in Helicoverpa
... a fourth (ok). The White, Brown, Scarlet and Ok proteins each have one transmembrane and one cytoplasmic domain and they heterodimerize to form functional transporters with different substrate specificities. We used CRISPR/Cas9 to create somatic and germ-line knockout mutations of these four genes i ...
... a fourth (ok). The White, Brown, Scarlet and Ok proteins each have one transmembrane and one cytoplasmic domain and they heterodimerize to form functional transporters with different substrate specificities. We used CRISPR/Cas9 to create somatic and germ-line knockout mutations of these four genes i ...
Functional Annotation
... Bio-ontologies are used to capture biological information in a way that can be read by both humans and computers. necessary for high-throughput “omics” datasets allows data sharing across databases ...
... Bio-ontologies are used to capture biological information in a way that can be read by both humans and computers. necessary for high-throughput “omics” datasets allows data sharing across databases ...
Evolution of a pseudo-control region in the mitochondrial genome of
... basis of the avian branch that might be shared by all recent bird species. However, the idea of an avian standard gene order was refuted by the discovery of a new mitochondrial gene rearrangement found in Falco peregrinus and other birds (Mindell et al. 1998). In this novel arrangement (Fig. 1) the ...
... basis of the avian branch that might be shared by all recent bird species. However, the idea of an avian standard gene order was refuted by the discovery of a new mitochondrial gene rearrangement found in Falco peregrinus and other birds (Mindell et al. 1998). In this novel arrangement (Fig. 1) the ...
Review Molecular Biology in Arteriosclerosis Research
... dramatic Impact on arteriosclerosis research. DNA clones for a small number of relevant proteins have been isolated, and studies are underway in numerous laboratories to extend these initial studies. The techniques of molecular biology will provide major advances in our understanding of numerous pro ...
... dramatic Impact on arteriosclerosis research. DNA clones for a small number of relevant proteins have been isolated, and studies are underway in numerous laboratories to extend these initial studies. The techniques of molecular biology will provide major advances in our understanding of numerous pro ...
Genes - Gerstein Lab Publications
... expression in tumour cells, e.g. in laryngeal squamous cell carcinoma [6] or in glioblastoma [7]. Pseudogenes are important in the study of molecular evolution, since they generally acquire mutations, insertions and deletions without any apparent evolutionary pressures. (However, in Drosophila for e ...
... expression in tumour cells, e.g. in laryngeal squamous cell carcinoma [6] or in glioblastoma [7]. Pseudogenes are important in the study of molecular evolution, since they generally acquire mutations, insertions and deletions without any apparent evolutionary pressures. (However, in Drosophila for e ...
Blue cone monochromacy: Causative mutations and associated
... followed by one or more M opsin genes [1,8]. The number of M genes is polymorphic: Approximately 25% of male caucasians have a single M gene, while 50% have two M genes and the remainder have 3 or more genes [1,8,9]. Expression of the L and M genes is regulated by the Locus Control Region (LCR), a c ...
... followed by one or more M opsin genes [1,8]. The number of M genes is polymorphic: Approximately 25% of male caucasians have a single M gene, while 50% have two M genes and the remainder have 3 or more genes [1,8,9]. Expression of the L and M genes is regulated by the Locus Control Region (LCR), a c ...
Polymorphic miRNA-mediated gene regulation: contribution to
... site content. Quite logically, given that they have to operate in all cell types, the 30 UTRs of housekeeping genes are depleted in target sites in general and (presumably as a means to avoid target sites) are shorter than the 30 UTRs of other genes [33]. Some genes are under evolutionary pressure t ...
... site content. Quite logically, given that they have to operate in all cell types, the 30 UTRs of housekeeping genes are depleted in target sites in general and (presumably as a means to avoid target sites) are shorter than the 30 UTRs of other genes [33]. Some genes are under evolutionary pressure t ...
A genome screen for linkage in Australian sibling-pairs with
... tosus.26–28 Chromosome 16q24 also showed evidence of linkage in inflammatory bowel disease29 as well as two independent screens of rheumatoid arthritis,25,30 and the region on 4q24 showed the strongest evidence of linkage outside the HLA region in a genome screen of rheumatoid arthritis.25 In additi ...
... tosus.26–28 Chromosome 16q24 also showed evidence of linkage in inflammatory bowel disease29 as well as two independent screens of rheumatoid arthritis,25,30 and the region on 4q24 showed the strongest evidence of linkage outside the HLA region in a genome screen of rheumatoid arthritis.25 In additi ...
"PCR-based Species Identification and Gene Tagging"
... maize leaf _Bots infected leaf pt3 infected leaf pt1 P sorghi pt3 P sorghi pt1 Marker ...
... maize leaf _Bots infected leaf pt3 infected leaf pt1 P sorghi pt3 P sorghi pt1 Marker ...
Article A Distinct Mitochondrial Genome with DUI
... Heterodonta, order Veneroida and is the sole living representative of the Arcticidae family (Morton 2011). This species, known as the longest-lived non colonial species with a maximum reported life span of 507 years, is of great interest for studies of aging in marine non model species (Strahl and A ...
... Heterodonta, order Veneroida and is the sole living representative of the Arcticidae family (Morton 2011). This species, known as the longest-lived non colonial species with a maximum reported life span of 507 years, is of great interest for studies of aging in marine non model species (Strahl and A ...
Preimplantation genetic diagnosis: State of the ART 2011
... nucleotide polymorphism arrays have been introduced clinically for PGD and PGS. For PGD, the use of SNP arrays brings with it ethical concerns as a large amount of genetic information will be available from each embryo. For PGS, RCTs need to be conducted using both array-CGH and SNP arrays to determ ...
... nucleotide polymorphism arrays have been introduced clinically for PGD and PGS. For PGD, the use of SNP arrays brings with it ethical concerns as a large amount of genetic information will be available from each embryo. For PGS, RCTs need to be conducted using both array-CGH and SNP arrays to determ ...
Advances in Environmental Biology Zahra Maryami, Arash Fazeli, Ali-Ashraf Mehrabi
... The main component in wheat flour is starch, which is formed of two type’s glucose polymers: amylose and amylopectin [1,2], amylose is the linear amylose (23-35%) and amylopectin is the highly branched amylopectin (68-75%) to the total starch [3]. The ratio of polymers is important as it affects pro ...
... The main component in wheat flour is starch, which is formed of two type’s glucose polymers: amylose and amylopectin [1,2], amylose is the linear amylose (23-35%) and amylopectin is the highly branched amylopectin (68-75%) to the total starch [3]. The ratio of polymers is important as it affects pro ...
Molecualr Biology and Evolution
... lies within the proteobacterial clade with bootstrap sup- smaller subclones of the n$K region in pUCl19. port of 80%. Normand et al. ( 1992) provided an additional test of the horizontal transfer hypothesis by ex- Sequencing amining the phylogeny of another nf gene, n$D. Initial sequencing was done ...
... lies within the proteobacterial clade with bootstrap sup- smaller subclones of the n$K region in pUCl19. port of 80%. Normand et al. ( 1992) provided an additional test of the horizontal transfer hypothesis by ex- Sequencing amining the phylogeny of another nf gene, n$D. Initial sequencing was done ...
The Nucleotide Sequence Determination of Catalases of Three
... It has been shown that C. glabrata is a more closely related species to S. cerevisiae than any other pathogenic Candida species16）. S. cerevisiae has two types of catalase, CTA1 and CTT117, 18）. The two catalases differ in sequence, localization, and transcriptional regulation17−21）. To know which t ...
... It has been shown that C. glabrata is a more closely related species to S. cerevisiae than any other pathogenic Candida species16）. S. cerevisiae has two types of catalase, CTA1 and CTT117, 18）. The two catalases differ in sequence, localization, and transcriptional regulation17−21）. To know which t ...
Mendel and After - U3A Site Builder Home Page
... The title of Mendel’s paper is ‘Experiments in plant hybridization’ and in the introduction he states explicitly that he is presenting the results of a detailed experiment, the aim of which was to establish a ‘generally applicable law governing the formation and development of hybrids’. Mendel’s co ...
... The title of Mendel’s paper is ‘Experiments in plant hybridization’ and in the introduction he states explicitly that he is presenting the results of a detailed experiment, the aim of which was to establish a ‘generally applicable law governing the formation and development of hybrids’. Mendel’s co ...
Part 3 - Bioinformatics.ca
... – Unfiltered predictions are too noisy for most applications – Organisms with short regulatory sequences are less problematic (e.g. ...
... – Unfiltered predictions are too noisy for most applications – Organisms with short regulatory sequences are less problematic (e.g. ...
Isolation and Characterization of a Histidine Biosynthetic Gene in
... containing the longest insert was sequenced completely and used for further analyses. Strain UTH903 was transformed with either pAt-IE or an empty pBluescript, and crude cell extracts were prepared for an AICAR production assay. The AICAR production observed with the cells transformed with pAt-IE (2 ...
... containing the longest insert was sequenced completely and used for further analyses. Strain UTH903 was transformed with either pAt-IE or an empty pBluescript, and crude cell extracts were prepared for an AICAR production assay. The AICAR production observed with the cells transformed with pAt-IE (2 ...