SilkDB: a knowledgebase for silkworm biology and genomics
... database is through the ‘Data’ module, where users can get an overview of the data content, data statistics and the correlations between each data type. The provided hyperlinks facilitate users to browse the details of each data entry directly. MapView and Search Engine are two self-developed tools ...
... database is through the ‘Data’ module, where users can get an overview of the data content, data statistics and the correlations between each data type. The provided hyperlinks facilitate users to browse the details of each data entry directly. MapView and Search Engine are two self-developed tools ...
Slide 1
... Cytoplasmic inheritance This results when a trait is entirely or partially encoded by an organelle (e.g. chloroplast or mitochondrion) genome. ...
... Cytoplasmic inheritance This results when a trait is entirely or partially encoded by an organelle (e.g. chloroplast or mitochondrion) genome. ...
Chromosomes and Diseases - Faculty of Science at Bilkent
... apes had 24 pairs of chromosomes and that the fusion of two of the ancestor's chromosomes (chromosomes 2p and 2q) created chromosome 2 in humans ...
... apes had 24 pairs of chromosomes and that the fusion of two of the ancestor's chromosomes (chromosomes 2p and 2q) created chromosome 2 in humans ...
The Difference Makers
... their living by getting copied into RNA over and over again. Broken transposons can provide raw materials that over time become complex gene-regulating switches. Many of the transcription factor binding sites important for controlling human and mouse genes may have come from transposable elements, r ...
... their living by getting copied into RNA over and over again. Broken transposons can provide raw materials that over time become complex gene-regulating switches. Many of the transcription factor binding sites important for controlling human and mouse genes may have come from transposable elements, r ...
Lecture_13_2005
... that are controlled by redundant genes. • Synthetic lethal screens • Synthetic lethal = when two mutations that are not essential for growth individually are essential when combined. • Done on a genome wide scale for yeast. ...
... that are controlled by redundant genes. • Synthetic lethal screens • Synthetic lethal = when two mutations that are not essential for growth individually are essential when combined. • Done on a genome wide scale for yeast. ...
Bioinformatics to Study PTC Bitter Taste Receptor 1. Go to Kathryn
... __________19.Click on Genome View button to see the chromosome location of the BLAST hit. On what chromosome have you landed? 20. Click on the marked chromosome to move to the TAS2R38 locus. 21. Click on the small blue arrow labeled Genes seq to display genes. The TAS2R38 gene occupies the whole fie ...
... __________19.Click on Genome View button to see the chromosome location of the BLAST hit. On what chromosome have you landed? 20. Click on the marked chromosome to move to the TAS2R38 locus. 21. Click on the small blue arrow labeled Genes seq to display genes. The TAS2R38 gene occupies the whole fie ...
Sex determination
... transferred from the Hfr strain. Genes from the donor Hfr strain first appeared in the F- strain at the times listed. Give the order of the genes on the bacterial chromosome and indicate the minimum distances between them. gly+ 3 min. his+ 14 min. bio+ 35 min. gal+ 36 min. pur+ 38 min. ...
... transferred from the Hfr strain. Genes from the donor Hfr strain first appeared in the F- strain at the times listed. Give the order of the genes on the bacterial chromosome and indicate the minimum distances between them. gly+ 3 min. his+ 14 min. bio+ 35 min. gal+ 36 min. pur+ 38 min. ...
How do we know that DNA carries genetic information?
... 1978: The first human gene is cloned – insulin 1982: Genetically-engineered insulin is approved for use 1985: PCR (Polymerase Chain Reaction) is invented ...
... 1978: The first human gene is cloned – insulin 1982: Genetically-engineered insulin is approved for use 1985: PCR (Polymerase Chain Reaction) is invented ...
Multiple Choice
... ____ 4. During mitosis, the a. DNA molecules unwind. b. histones and DNA molecules separate. c. DNA molecules become more tightly coiled. d. nucleosomes become less tightly packed. ____ 5. Unlike DNA, RNA contains a. adenine. c. phosphate groups. b. uracil. d. thymine. ____ 6. Which type(s) of RNA i ...
... ____ 4. During mitosis, the a. DNA molecules unwind. b. histones and DNA molecules separate. c. DNA molecules become more tightly coiled. d. nucleosomes become less tightly packed. ____ 5. Unlike DNA, RNA contains a. adenine. c. phosphate groups. b. uracil. d. thymine. ____ 6. Which type(s) of RNA i ...
Genetics: The Science of Heredity
... ______ 19. Vultures, which feed on the bodies of dead organisms, are a. first-level consumers. c. producers. b. scavengers. d. herbivores. ______ 20. Consumers that eat both plants and animals are called a. omnivores. c. carnivores. b. herbivores. d. scavengers. ______ 21. If a kestrel eats a mouse ...
... ______ 19. Vultures, which feed on the bodies of dead organisms, are a. first-level consumers. c. producers. b. scavengers. d. herbivores. ______ 20. Consumers that eat both plants and animals are called a. omnivores. c. carnivores. b. herbivores. d. scavengers. ______ 21. If a kestrel eats a mouse ...
File
... The order of the bases of DNA determines the information available for building and maintaining an organism. This order is referred to as genetic code. ...
... The order of the bases of DNA determines the information available for building and maintaining an organism. This order is referred to as genetic code. ...
Topic 3: Genetics (18 hours)
... Developments in scientific research follow improvements in technology—gene sequencers are used for the sequencing of genes. (1.8) Understandings: International-mindedness: • A gene is a heritable factor that consists of a length of • Sequencing of the human genome shows that all humans DNA and influ ...
... Developments in scientific research follow improvements in technology—gene sequencers are used for the sequencing of genes. (1.8) Understandings: International-mindedness: • A gene is a heritable factor that consists of a length of • Sequencing of the human genome shows that all humans DNA and influ ...
second of Chapter 10: RNA processing
... Exon-shuffle model • Introns may play a role in gene evolution. • In some proteins, each exon has its own independent folding characteristics. • Folding domains (=exons) can be grouped together to give new proteins with new functions. • This is called the exon-shuffle model. • Not all genes have do ...
... Exon-shuffle model • Introns may play a role in gene evolution. • In some proteins, each exon has its own independent folding characteristics. • Folding domains (=exons) can be grouped together to give new proteins with new functions. • This is called the exon-shuffle model. • Not all genes have do ...
Gene
... • We have 1000’s of genes and each one is found at a specific location on a specific chromosome – What does that mean? • All genes have a certain part (location) of a chromosome where they are found ...
... • We have 1000’s of genes and each one is found at a specific location on a specific chromosome – What does that mean? • All genes have a certain part (location) of a chromosome where they are found ...
Slide 1
... frequency – Finds “putative” coding regions, not introns, exons, or splice sites • TestCode finds ORFs based on compositional bias with a periodicity of three ...
... frequency – Finds “putative” coding regions, not introns, exons, or splice sites • TestCode finds ORFs based on compositional bias with a periodicity of three ...
STRUCTURAL CHROMOSOMAL ABERRATIONS Structural
... In this mutation, the mutants genes are displayed twice on the same chromosome due to duplication of these genes. This can prove to be an advantageous mutation as no genetic information is lost or altered and new genes are gained Normal chromosome before mutation ...
... In this mutation, the mutants genes are displayed twice on the same chromosome due to duplication of these genes. This can prove to be an advantageous mutation as no genetic information is lost or altered and new genes are gained Normal chromosome before mutation ...
Document
... 4. In the following diagrams, the vertical lines represent EcoRI restriction sites. An asterisk over the site represents a polymorphism (presence or absence of the site in individuals) in the population. The double arrow represents the boundaries of the cloned DNA used in the Southern blot analysis. ...
... 4. In the following diagrams, the vertical lines represent EcoRI restriction sites. An asterisk over the site represents a polymorphism (presence or absence of the site in individuals) in the population. The double arrow represents the boundaries of the cloned DNA used in the Southern blot analysis. ...
Alternative splicing
... but also codon bias, intron-exon boundaries and transcriptional control elements (e.g. the TATA box) However, the sequences can be quite variable!! Alternative approach: To use previously identified genes as a guide, try to assign similar (homologous) to any existing genes. Exceptions: pseudogenes ...
... but also codon bias, intron-exon boundaries and transcriptional control elements (e.g. the TATA box) However, the sequences can be quite variable!! Alternative approach: To use previously identified genes as a guide, try to assign similar (homologous) to any existing genes. Exceptions: pseudogenes ...
Document
... custom images of the physical or genetic positions of specified sets of genes in one or more genomes or parts of genomes. The positions of user-selected sets of genes are displayed along the chromosomes based on either physical or genetic distances. Multiple sets of genes can be shown simultaneously ...
... custom images of the physical or genetic positions of specified sets of genes in one or more genomes or parts of genomes. The positions of user-selected sets of genes are displayed along the chromosomes based on either physical or genetic distances. Multiple sets of genes can be shown simultaneously ...
Chapter 10: Retroelements in the Mouse
... (LINE) which alone account for ~20% of the mouse genome __________________ are large numbers of non-autonomous retroelements that encode no proteins and are dependent on the reverse transcriptase-competent autonomous retroelements for their mobility. Which of the following have open reading frames t ...
... (LINE) which alone account for ~20% of the mouse genome __________________ are large numbers of non-autonomous retroelements that encode no proteins and are dependent on the reverse transcriptase-competent autonomous retroelements for their mobility. Which of the following have open reading frames t ...
Slide 1
... Rich in sulfides (black smokers), Ba-Ca-Si (white smokers); Chimneys can be up to 60 m. One species of green-sulfur bacterium (Chlorobiaceae) called GSB1 uses the faint red glow of black smokers to power photosynthesis! Chemotrophic bacteria extract energy from sulfide reactions, and give the energy ...
... Rich in sulfides (black smokers), Ba-Ca-Si (white smokers); Chimneys can be up to 60 m. One species of green-sulfur bacterium (Chlorobiaceae) called GSB1 uses the faint red glow of black smokers to power photosynthesis! Chemotrophic bacteria extract energy from sulfide reactions, and give the energy ...
introduction - Genomics
... Whole genome sequences are now available for several organisms, including human, mouse, Drosophila, Fugu and Caenorhabditis, and for these and many more species there are large, publicly available collections of ESTs. Scientists are now faced with the challenge of extracting information from these s ...
... Whole genome sequences are now available for several organisms, including human, mouse, Drosophila, Fugu and Caenorhabditis, and for these and many more species there are large, publicly available collections of ESTs. Scientists are now faced with the challenge of extracting information from these s ...
Human genome
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.