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Name: Date: Per:______ DNA Guided Reading There are two types
Name: Date: Per:______ DNA Guided Reading There are two types

... Mistakes in the process of meiosis can result in a new organism with more or fewer chromosomes than normal. Individuals with Down’s syndrome have an extra copy of chromosome twenty-one. This results in a variety of physical and/or mental conditions. Many genetic disorders are caused by recessive gen ...
DNA and RNA are nucleic acids that carry out cellular
DNA and RNA are nucleic acids that carry out cellular

... The entire genetic content of a cell is known as its genome and the study of genomes is genomics. In eukaryotic cells, but not in prokaryotes, DNA forms a complex with histone proteins to form chromatin, the substance of eukaryotic chromosomes. A chromosome may contain tens of thousands of genes. Ma ...
DNA and RNA are nucleic acids that carry out cellular
DNA and RNA are nucleic acids that carry out cellular

... The entire genetic content of a cell is known as its genome and the study of genomes is genomics. In eukaryotic cells, but not in prokaryotes, DNA forms a complex with histone proteins to form chromatin, the substance of eukaryotic chromosomes. A chromosome may contain tens of thousands of genes. Ma ...
Huntington`s disease
Huntington`s disease

... Linkage--Recombination during meiosis separates genes 1. Genes on different chromosomes assort independently 2. Genes on the same chromosome are linked 3. This linkage is not absolute ...
What is a gene?
What is a gene?

... Transcription factors, defined here specifically as proteins containing domains that suggest sequencespecific DNA-binding activities, are classified based on the presence of 50+ conserved domains. Links to resources that provide information on mutants available, map positions or putative functions f ...
Introduction and review Lecture 1: Jan. 18, 2006
Introduction and review Lecture 1: Jan. 18, 2006

... • Genetics is the study of inherited traits • Each organism has its own “Genetic Blueprint” that makes it different from others. • This information is stored in the chromosomes located in the nucleus. • The genetic information is stored as discrete instructions called “genes”. • Their existence was ...
DNA unit Summary
DNA unit Summary

... DNA molecule, allowing free nucleotides in the nucleus to bond to the new single strands by base-pairing. This process will continue until the entire molecule has been unzipped and replicated. Each new strand formed is a complement of one of the original, or parent, strands. That means it matches th ...
D: Glossary of Acronyms and Terms
D: Glossary of Acronyms and Terms

... Nonconjugative plasmid: A plasmid incapable of initiating or directing the process of conjugation. (Compare conjugative plasmid.) Nontransferable plasmid: See nonconjugativeplasmid. Nucleic acid: A macromolecule composed of sequences of nucleotide bases; DNA or RNA. Nucleotide (base): The unit of nu ...
Instructional Objectives—DNA, RNA and Protein Synthesis
Instructional Objectives—DNA, RNA and Protein Synthesis

... Describe the importance of each of the following molecules during protein synthesis? DNAmRNAtRNARibosomesObjective 12:Given a DNA sequence transcribe it into mRNA and determine the amino acid sequence that will be produced during translation.  Transcribe the following strand of DNA into mRNA. Then ...
Advances in Genetics
Advances in Genetics

... out with a belief that there is more to life than mere chemistry – will lose their faith while at college. I believe this is also the cause of the widespread self-destructive and self-denigrating behaviors we see throughout our culture.” p. v. “… the “Primary Hypothesis” (that mutation/selection can ...
Topic guide 7.7: Genes and evolution
Topic guide 7.7: Genes and evolution

... code, many amino acids are coded for by more than one base triplet. However, molecular biologists now know that not all DNA codes for proteins and they are now finding that silent mutations may be involved with certain genetic diseases, such as Marfan’s syndrome, if they occur in a regulatory portio ...
14-2 Human Chromosomes – Reading Guide
14-2 Human Chromosomes – Reading Guide

... 1. Genes make up only a small part of chromosomes; only about _________% of chromosome’s DNA functions as genes. 2. The first two human chromosomes whose sequences were determined were chromosome ______ & ______. 3. Chromosome 21 contains about _______ genes, including one associated with amyotropic ...
Phylogenetic DNA profiling : a tool for the investigation of poaching
Phylogenetic DNA profiling : a tool for the investigation of poaching

... procedure. Reactions were performed in a total volume of 25 µl using 1-10 ng template DNA. The final concentration of the components in reaction mix was as follows; 10 mM Tris-HCl (pH 8.3), 50 mM KCl, 2.5 mM MgCl2, 0.25 µM each primer, 200 µM dNTP’s, 1 unit Taq polymerase (Life Technologies, Austral ...
HIV GENOTYPE ASSAY
HIV GENOTYPE ASSAY

... entire region Protease (codon 1-99) and two-thirds RT region (1335). Big Dye Terminator chemistry is used to permit a resolution of 600 bases on the 3100 Genetic Analyzer  Sequence Purification-removes unincorporated Big terminators from samples so they do not interfere with sample sequencing & ana ...
Standardized Test Prep Gene Technologies and Human Applications
Standardized Test Prep Gene Technologies and Human Applications

... Student essays should be supported by facts and logical arguments. Consider peer review of essays. Sample argument: No, such information might create biases against those whose diseases are well-researched as opposed to those about which less is known. Genetic research should not be abused because t ...
Sequence - andreawise
Sequence - andreawise

... the sequence (recorded in the Science Life literature database called PUBMED).  You can search for similar sequences using the feature called BLAST (by inputting all or part of a DNA or amino acid sequence) and compare two or more sequences. ...
30. Insulin Prodution
30. Insulin Prodution

... Create new account Upload ...
Lecture 6 Gene expression: microarray and deep sequencing
Lecture 6 Gene expression: microarray and deep sequencing

... amount of data from a single run ~ amount of data from the human genome project ...
Units 5 and 6: DNA and Protein Synthesis 1/22 Vocabulary
Units 5 and 6: DNA and Protein Synthesis 1/22 Vocabulary

... Translation: process of interpreting the DNA message and building the protein ○ Begins when mRNA attaches to a ribosome (contains ribosomal RNA (rRNA); in the cytoplasm) ○ Each three-base nucleotide sequence on the mRNA is called a codon. o Each codon specifies a particular amino acid; for example, ...
Genetic terms, punnett squares
Genetic terms, punnett squares

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a instructions to the candidates

... NB: No candidate will leave the Examination Hall before the expiry of the period of at least 45 minutes of the start of the paper. 1. Write your Roll Number and specific subject B,C or D clearly in the designated space on the answer sheet and on the question paper. 2. The enclosed paper contains 2 S ...
Unit VII: Genetics
Unit VII: Genetics

... selective breeding has been occurring for 1000s of years ...
DNA 1: Today`s story, logic & goals
DNA 1: Today`s story, logic & goals

... Modes of inheritance DNA, RNA (e.g. RNAi), protein (prion), & modifications (e.g. 5mC) “Horizontal” (generally between species) transduction, transformation, transgenic “Vertical” Mitosis: duplication & division (e.g. somatic) Meiosis/fusion: diploid recombination, reduction Maternal (e.g. mitochon ...
Design Part 2. PPT
Design Part 2. PPT

... culture, clothes, environment,surgery ...
Where Do New Genes Come From? A Computational Analysis of
Where Do New Genes Come From? A Computational Analysis of

... Identify horizontal transfers Infer functional associations Snel, Bork, Huynen. PNAS 2002 ...
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Human genome



The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.
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