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Re-Designing Humans Part Two If Humans were built to Last Joseph M. Rosen, M.D. April 17th , 2003 Engineering 005 Summary of the Course: Re-designing Humans Form and Function (Sci Am March 2001) Technologies – surgery, robotics, virtual reality and genetic engineering Applications – walking, senses and internal organs and outward appearance Re-Design vs. Re-Evolution – changing future generations – Genes for Beauty Genotype is a function of the human genome: Critical discovery April 25,1953 DNA is the template for RNA to make proteins: human genome = DNA Human transformation – re-designing humans: Phenotype definition: Nature and Nurture in Humans Phenotype is the expression of nature and nuture in a species or individual Nature is what we inherit from generation to generation - genotype Nuture is our expression of civilization, culture, clothes, environment,surgery Limitations of surgery, genome and robotics: Lamarck and Nanosurgery: Operating on the Germline Surgery on the genotype to alter form and function Recent ability to make major changes in evolution: DNA and the Human Genome Genetic engineering could allow surgery to alter future generations This would dramatically alter choices for human evolution in both form and function Nature’s information code for life’s expression: Nanosurgery to change future generations by human choice Each cell has the potential to clone an entire person Hidden genes to express Wings, fins and other parts ? Wings Lets Walk first before we Fly “ flying squirrel” Built to Last Lets ‘not’ age Anti-Aging: Re-designing Humans Human purpose – The Selfish Gene 100 Years Young Person Designed for a Healthy Old Age Mike McKenna thesis work –first virtual humans : How do we walk – making avatar – virtual creatures Mike McKenna thesis work –first virtual humans : Using Virtual Reality to teach us about Walking so we can Last If Humans were built to last: Flaws and Fixes If Humans were built to last: List of Flaws – Walk this Way Bioweapons can effect the will of the nation through terror and the economy blowback risk to the enemy If Humans were built to last: List of Fixes – Walk this Way Bioweapons can effect the will of the nation through terror and the economy BW have a potentially unique outcome –can change policy and military strategy Re-Designing Humans Other Systems What other systems need to be modified to remain young Getting A Head Vision Hearing Trachea Esophagus Get a Plumber Male Female If Humans were built to last: Flaws and Fixes-Plan a Head If Humans were built to last: Call a Plumber - Male If Humans were built to last: Call a Plumber - Female Deformities versus Beauty: Re-Think role of Surgery Cosmetics – Operating on Normal people to make them ‘beautiful’ Curing Aging, Fatness, Culture Some Cultures change their phenotype (shape) Plastic surgery to alter the human form - skin: Surgical Recontruction for deformities is not Cosmetic Human transformation – re-designing humans: Phenotype alteration through the clothes we wear Human transformation – re-designing humans: Phenotype alteration through the masks and modifications Human transformation – re-designing humans: Phenotype alteration through scarification and modification Cosmetic Surgery Next