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Sepsis review St Luc Hospital, September 2003 By Antonios Liolios
Sepsis review St Luc Hospital, September 2003 By Antonios Liolios

... Finally coagulation is activated with release of thrombin and the formation of the fibrin clot. The purpose of this pathway is to “wall off” the infection. Immune system overstimulation is not central. What has been recently recognized is that cytokines may actually be beneficial in sepsis. The immu ...
2011 Advanced CustomVue Technology Brochure
2011 Advanced CustomVue Technology Brochure

... Statements regarding the potential benefits of wavefront-guided LASIK (CustomVue) are based upon the results of clinical trials. These results are indicative of not only the CustomVue Treatment but also the care of the clinical physicians, the control of the surgical environment by those physicians, ...
Preparing Your Patients for Biosimilars
Preparing Your Patients for Biosimilars

... are starting to be approved for use in rheumatology patients, and pharmaceutical insiders predict these drugs will be a game changer when they hit clinics in the coming years. “Americans should see biosimilars in clinic in the next year or two,” said Stephen Feldman, MD. Feldman, a dermatologist at ...
Tuberculosis
Tuberculosis

... gamma in supernatant, currently at third generation test – Quantiferon Gold In-tube • Elispot – measure of individual T-cells that produce interferon gamma. Continuity ...
Sense Organ Disorders
Sense Organ Disorders

... sent to the brain. There, instructions are formulated that travel through the cranial nerves to the skeletal muscles. In the face and throat, for example, these muscles control movements for smiling and swallowing. A brief review of the sense organs will be given here. The eye is the organ of vision ...
ERS-ATS COPD Guidelines
ERS-ATS COPD Guidelines

... The medications for COPD currently available can reduce or abolish symptoms, increase exercise capacity, reduce the number and severity of exacerbations, and improve health status. ...
Clinical issues associated with the use of complementary and alternative medicine chapter 2
Clinical issues associated with the use of complementary and alternative medicine chapter 2

... perhaps two, interventions taken from a whole treatment system. For instance, there are hundreds of small studies examining the efficacy of acupuncture needling alone for treating asthma, pain, hypertension or nausea. Yet, in practice, acupuncture needling would be just one of a portfolio of interve ...
Purulent pericarditis: Review of a 20
Purulent pericarditis: Review of a 20

... but the presence of mediastinitis and empyema and echocardiographic evidence of pericardial effusion (2 patients) ; no tamponade but a recent urinary tract infection and pericardial effusion with marked toxicity and leukocytosis (I patient), and pyopneumothorax with subsequent acute constrictive per ...
Pulmonary rehabilitation: insight into current trends Anabel Sciriha, Stephen Montefort Abstract
Pulmonary rehabilitation: insight into current trends Anabel Sciriha, Stephen Montefort Abstract

... disease (AD) accounts for 50-70% of cases followed by Vascular dementia, Lewy Body Disease, fronto-temporal dementia and dementia secondary to disease.2 According to an estimate from World Health Organization (WHO), dementia is responsible for more years lived with disability in people older than 60 ...
Anti-TNF Monoclonal Antibodies in Inflammatory Bowel Disease
Anti-TNF Monoclonal Antibodies in Inflammatory Bowel Disease

... who fail conventional medical therapy require biological treatment with monoclonal antibodies (mAbs). Although mAbs are highly effective for induction and maintenance of clinical remission, not all patients respond, and a high proportion of patients lose response over time. One factor associated wit ...
Final Labeling Text
Final Labeling Text

... were observed in orally dosed rats. No fetal harm was observed with oral administration of eliglustat to pregnant rabbits at dose levels 10 times the recommended human dose. CERDELGA should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Clinical Con ...
Ibuprofen Bril 200 mg Film
Ibuprofen Bril 200 mg Film

... NSAIDs at any time during treatment, with or without warning symptoms or a previous history of serious GI events. The risk of GI bleeding, ulceration or perforation is higher with increasing NSAID doses, in patients with a history of ulcer, particularly if complicated with haemorrhage or perforation ...
Presentation
Presentation

... • Currently, there is no difference in OS at a median follow-up of 1.5 years post-ASCT • Lenalidomide prolonged TTP within patient stratification by high and low β2M, and prior thalidomide or lenalidomide induction therapy • Lenalidomide maintenance produced some hematologic toxicity, but this was n ...
entire SUMJ Dundee Vol1 - Issue 2 as a PDF
entire SUMJ Dundee Vol1 - Issue 2 as a PDF

... environment  for  treating  patients  as  there  is  time  available  to  build  a  therapeutic  relationship.  This  can  prove  especially  important  for  patients  with  a  dual  diagnosis,  who  need concurrent treatment for more than one condition. This also provides an opportunity  for  the  ...
Prophylaxis of CMV infection and disease
Prophylaxis of CMV infection and disease

... mg/m2 three times daily) from day –5 until engraftment, followed until day +100 by IV ganciclovir (5 mg/kg daily from Monday to Friday) and oral acyclovir (800 mg three times daily on weekend). ...
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Amr Mustafa Abdelhamid Alhammady_338_IJAR
Amr Mustafa Abdelhamid Alhammady_338_IJAR

... Although significant progress has been made to understand the molecular mechanism for advancement from acute liver injury to fibrosis and cirrhosis, there is no antifibrotic therapy actually available for patients with chronic liver disease. The mainstay is to treat the underlying liver disease. If ...
Maltose Facts
Maltose Facts

... viruses and theoretically, the Creutzfeldt-Jakob disease (CJD) agent. All infections thought by a physician possibly to have been transmitted by this product should be reported by the physician or other healthcare provider to Octapharma. The physician should discuss the risks and benefits of this pro ...
Addition of sildenafil to bosentan monotherapy in pulmonary arterial
Addition of sildenafil to bosentan monotherapy in pulmonary arterial

... developed that target the prostacyclin (epoprostenol, treprostinil and iloprost), nitric oxide (sildenafil) or endothelin (bosentan) pathways. ...
Asthma
Asthma

... complaining of increased shortness of breath and using his short-acting beta agonist 3 times per week. Which of the following statements is correct regarding management of this patient? a) continue current management as symptoms require beta agonist less than once daily b) add a long acting beta ago ...
Guidelines for medical treatment of acute Kawasaki disease: Report
Guidelines for medical treatment of acute Kawasaki disease: Report

... first marketed have confirmed the efficacy and safety of singleuse IVIG therapy. In addition, the incidence of coronary artery lesions (CAL) has gradually decreased every year since IVIG treatment was introduced in Japan.1 The incidence of giant coronary artery aneurysms (CAA), however, has remained ...
Respiratory medicines for children: current evidence, unlicensed use and research priorities
Respiratory medicines for children: current evidence, unlicensed use and research priorities

... rescue medication use, lung function, airway hyperresponsiveness, quality of life and exacerbation rates [7, 8]. Most children with asthma on low-dose ICS treatment attain adequate control of their asthma and normal lung function [9]. Both the magnitude of the beneficial effect and the amount of var ...
Diette GB, Patino CM, Merriman B, Paulin L, Riekert K, Okelo S, Thompson K, Krishnan JA, Quartey R, Perez-Williams D, Rand C. Patient factors that physicians use to assign asthma treatment. Arch Intern Med. 2007;167(13): p.1360-6.
Diette GB, Patino CM, Merriman B, Paulin L, Riekert K, Okelo S, Thompson K, Krishnan JA, Quartey R, Perez-Williams D, Rand C. Patient factors that physicians use to assign asthma treatment. Arch Intern Med. 2007;167(13): p.1360-6.

... physicians from the American College of Chest Physicians (PSs) and 225 practicing physicians from the American Academy of Family Physicians (FPs), representing 34% of potentially eligible respondents. The PSs and FPs resided in 49 and 43 US states and territories, respectively. While we had few data ...
Australian public assessment for Follitropin alfa (rch)
Australian public assessment for Follitropin alfa (rch)

... • The EU application was approved on the basis of the same clinical data as contained in the current Australian application, obtained by comparing Bemfola with Gonal-f in the ART indication. The EMA approved extrapolation of these clinical findings to the full list of indications, based on the biosi ...
Noninfectious Posterior Uveitis Noninfectious
Noninfectious Posterior Uveitis Noninfectious

... oral steroids may not be necessary. In birdshot chorioretinopathy, for instance, patients can present with only a few cells and no CME or vasculitis, so steroids are not necessary. In these rare cases, the patient needs longterm immunosuppression, and we start with an antimetabolite, knowing that it ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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