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Impact on the quality of life of dermatological patients in southern
Impact on the quality of life of dermatological patients in southern

... In the last ten years, there has been an increasing interest in assessing the quality of life of patients with skin diseases as well as in the development of methods of assessment.1-4 Patients with skin diseases may have their lives affected in many ways. Skin diseases are major causes of morbidity ...
Insertion of endobronchial nitinol coils to improve lung function in
Insertion of endobronchial nitinol coils to improve lung function in

... functional diseased lung segments, allowing air to flow to healthier parts of the lungs, with the aim of improving gas exchange and, as a result, lung function. The procedure is intended to improve lung function in patients with upper or lower lobe heterogeneous emphysema, as well as in patients wit ...
Cervical Dystonia - California Physical Therapy Association
Cervical Dystonia - California Physical Therapy Association

... ROC plots sensitivity by 1-specificity (want combination high sens and low 1-spec) ...
Assessment of Appropriate Use of Stress Ulcer
Assessment of Appropriate Use of Stress Ulcer

Ibuprofen Bril 400 mg Film
Ibuprofen Bril 400 mg Film

... NSAIDs at any time during treatment, with or without warning symptoms or a previous history of serious GI events. The risk of GI bleeding, ulceration or perforation is higher with increasing NSAID doses, in patients with a history of ulcer, particularly if complicated with haemorrhage or perforation ...
Novel oral anticoagulants and reversal agents
Novel oral anticoagulants and reversal agents

... there are no specific reversal agents currently available for the NOACs. Despite the fact that the need for reversal of any anticoagulant is relatively rare and the rapid offset of the NOACs obviates reversal in most situations, antidotes for the NOACs would be beneficial to manage patients who requ ...
Document
Document

... frequency and severity. Subsequent studies have been less impressive, with many failing to meet their primary endpoints of migraine frequency,9-11 number of days with migraine,10 number of total single doses to treat a migraine attack,10 and severity.11 In this issue of JMCP, Mitchell et al. have pr ...
Burden of Tyrosine Kinase Inhibitor Failure in Patients with Chronic
Burden of Tyrosine Kinase Inhibitor Failure in Patients with Chronic

... [34]. Furthermore, an attitudinal study of CML patients found that the most common reasons for non-adherence were simply forgetting to take the dose and to avoid experiencing side effects [44]. Suboptimal response: A suboptimal response, referred to as a warning response by the 2013 European Leukemi ...
The Pharmacist`s Role in Obesity Management - Power
The Pharmacist`s Role in Obesity Management - Power

... The community pharmacist is an essential resource for overweight and obese patients who are attempting to manage their weight. Among all health professionals, pharmacists are perhaps most often asked about weight-loss agents, as they dispense prescription and nonprescription therapies for weight man ...
Growth Hormone Deficiency in Fungal Exposure
Growth Hormone Deficiency in Fungal Exposure

... et al., 2002; Sherris et al., 2005). Fungal antigens activate helper T-lymphocytes in the blood of CRS patients, producing cytokines that recruit (interleukins 13 [IL-13]), (interferon g [INF-g]), and activate (IL-5) eosinophils. Lymphocytes from normal controls do not activate helper T-lymphocytes ...
c) people with a family history of CJD
c) people with a family history of CJD

... which are inherited from one parent. These may produce forms of the PrP molecule which are more likely to be converted into abnormal form. Finally, in CJD acquired by transmission (variant and iatrogenic), PrPsc molecules enter the body via an outside source and corrupt the PrPc of the host. The PrP ...
Title: A TRIAL OF BECLOMETHASONE/FORMOTEROL IN COPD USING EXACT-PRO TO MEASURE EXACERBATIONS
Title: A TRIAL OF BECLOMETHASONE/FORMOTEROL IN COPD USING EXACT-PRO TO MEASURE EXACERBATIONS

... An exacerbation is usually an event diagnosed by a physician after the patient has reported increased symptoms/signs. However, many exacerbations are not reported by patients [2]. In clinical trials, this under-reporting leads to an under-estimate of exacerbation frequency [8]. Patient diaries can i ...
Final scope
Final scope

... making recommendations involving a choice between alternative interventions. A review of the economic evidence will be conducted and analyses will be carried out as appropriate. The preferred unit of effectiveness is the quality-adjusted life year (QALY), and the costs considered will usually be onl ...
shoulder arthroplasty protocol - Vanderbilt University School of
shoulder arthroplasty protocol - Vanderbilt University School of

... considered using an empirical regbe vigorously treated as any other imen (Table 3). In addition, antibipatient with elimination of the otic prophylaxis may be considered source of the infection (incision and drainage, when the higher-risk dental procedures (again, as endodontics, extraction) and app ...
Uterine Fibroids 1 Non-‐cancerous tumors called uterine
Uterine Fibroids 1 Non-‐cancerous tumors called uterine

... noted  that  the  most  important  outcomes  to  study  would  vary  depending  on  the  severity  of  the  disease  in  the  patients   under  study.  Conversely,  the  most  important  treatment  options  to  study  would  be  driven ...
2005 American Heart Association Guidelines for Cardiopulmonary
2005 American Heart Association Guidelines for Cardiopulmonary

... Systemic corticosteroids are the only proven treatment for the inflammatory component of asthma, but the onset of their anti-inflammatory effects is 6 to 12 hours after administration. A comprehensive search of the literature by the Coch-rane approach (including pediatric and adult patients) determi ...
Delineation of candidate genes responsible for structural brain
Delineation of candidate genes responsible for structural brain

... The summary of clinical features of 21 patients with variable size deletions between 6q25.3-q27 (seven patients from our cohort and 14 patients previously reported in the literature) are listed in Table 1. Among these patients, 14 were female, 7 were male. In the 12 families with known inheritance p ...
kidney failure treatment options
kidney failure treatment options

... Will I have fluid restrictions when I’m on dialysis? Fluid intake is reduced when patients have chronic kidney disease and are on dialysis. Too much fluid can cause high blood pressure, shortness of breath, and heart damage. Discuss with your physician how much water you can drink each day. Can dial ...
InfinityHIT VTE-Stroke MU Rules Presentation
InfinityHIT VTE-Stroke MU Rules Presentation

Investigation of Multidrug-resistant TB — Republic of the
Investigation of Multidrug-resistant TB — Republic of the

Use of a Loading Dose of Levetiracetam or Not?
Use of a Loading Dose of Levetiracetam or Not?

... prolonged, the likelihood of poor outcomes increases dramatically. In view of this, the most recent practice guidelines for the treatment of status epilepticus (SE) suggest that SE be defined as 5 minutes or more of (i) continuous clinical and/or electrographic seizure activity or (ii) recurrent sei ...
Tuberculosis
Tuberculosis

... gamma in supernatant, currently at third generation test – Quantiferon Gold In-tube • Elispot – measure of individual T-cells that produce interferon gamma. Continuity ...
Case presentation General Surgery
Case presentation General Surgery

... No human trials found involving OM Animal studies: May have a role in bone infection – 28 days of treatment in rabbits with OM – Tigecycline/oral rifampicin: 100% infection clearance ...
Oral versus parenteral antimicrobials for the treatment of cellulitis: a
Oral versus parenteral antimicrobials for the treatment of cellulitis: a

... to parenteral antimicrobials in time to no advancement of cellulitis. Treating these patients with oral antimicrobials also appears to be effective and safe, with each group experiencing similar rates of failure of treatment, improvement in pain scores and side effects of treatment. Patients in eith ...
Preparing Your Patients for Biosimilars
Preparing Your Patients for Biosimilars

... are starting to be approved for use in rheumatology patients, and pharmaceutical insiders predict these drugs will be a game changer when they hit clinics in the coming years. “Americans should see biosimilars in clinic in the next year or two,” said Stephen Feldman, MD. Feldman, a dermatologist at ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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