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Efficacy and Safety Considerations in Topical Treatments for Atopic
Efficacy and Safety Considerations in Topical Treatments for Atopic

... erythematous papules and plaques and the formation of large lichenified plaques resulting from chronic lesions. In adults, AD usually presents in flexural folds, the face and neck, upper arms and back, and the dorsa of hands, feet, fingers, and toes. Most children outgrow their AD but continue to ha ...
Odor identification test as an indicator of idiopathic REM sleep
Odor identification test as an indicator of idiopathic REM sleep

... iRBD and a Lewy body disease, such as PD, than in OSAS patients. Besides, to differentiate iRBD and PD from OSAS, the OSIT-J with a cutoff value of 8.5 yielded sensitivity of 88.2 and 85.3% and specificity of 83.3 and 85.7%, respectively. Therefore, a cutoff value of 8 was considered useful for diff ...
Revised: September 2016 AN: 00674/2016 SUMMARY OF
Revised: September 2016 AN: 00674/2016 SUMMARY OF

... associated monitoring of serum phenobarbital levels. The phenobarbital serum concentration may be checked after steady state has been achieved, and if it is less than 15 µg/ml the dose may be adjusted accordingly. If seizures recur the dose may be raised up to a maximum serum concentration of 45 µg/ ...
Introduction: There are a variety of crystals that may be
Introduction: There are a variety of crystals that may be

... where they are associated with degenerative changes. The crystals may provoke an acute attack of synovitis- referred to as pseudo-gout. The deposits are often visible as a fine layer of calcification overlying the menisci and articular cartilage of the knee- termed chondrocalcinosis; and BCP crystal ...
Acute Oncology Services Clinical Guidelines
Acute Oncology Services Clinical Guidelines

... condition to allow understanding of its context and importance, followed by the expected clinical presentations. A range of investigations is suggested, with the understanding that these will be tailored to individual cases. In most instances the subsequent management protocols mention generic drugs ...
Selected Properties of Darunavir Other names Prezista®, TMC
Selected Properties of Darunavir Other names Prezista®, TMC

... showed that darunavir pharmacokinetics were not significantly affected. There are currently no pharmacokinetic data of darunavir in HIV-infected subjects with severe renal impairment or endstage renal disease; however a significant increase in darunavir would not be expected in such subjects, due to ...
Guidelines for Medicine - The Clinical Establishments
Guidelines for Medicine - The Clinical Establishments

... of health care. Asthma can be defined as a chronic inflammatory disorder of the airways. Different terms such as allergic or asthmatic bronchitis, wheezy bronchitis, intrinsic and extrinsic asthma are frequently employed in clinical practice. Asthma commonly begins in childhood and early youth, but ...
The changing spectrum of pulmonary disease in patients with HIV
The changing spectrum of pulmonary disease in patients with HIV

... weeks after starting tuberculosis therapy developed immunological reactions, whereas only one out of 15 subjects developed such reactions when starting after a delay of more than 6 weeks. For physicians treating patient populations in which tuberculosis is common, the potential for immune reconstitu ...
Mandibular advancement splints for the treatment of sleep apnea
Mandibular advancement splints for the treatment of sleep apnea

... treated with an oral device. However there are a further 25% of patients who still show a significant improvement, reducing AHI by 50% or more. The remaining 35–40% of patients will not respond (defined as less than 50% reduction in AHI) and some patients will even show a worsening of OSA with an or ...
here - BITS Embryo
here - BITS Embryo

... • What is the clinical impact, cost, and costeffectiveness of strategies for preventing opportunistic infections in patients with ...
Relvar/Breo
Relvar/Breo

... From the Global Strategy for Diagnosis, Management and Prevention of COPD 2015,© Global Initiative for Chronic Obstructive Lung Disease (GOLD), all rights reserved. Available from http://www.goldcopd.org ...
Medical Therapy for Pulmonary Arterial Hypertension*
Medical Therapy for Pulmonary Arterial Hypertension*

Classification and management of primary angle closure disease
Classification and management of primary angle closure disease

... iridotomy and one in eyes with medically uncontrolled CACG following LPI. The first trial consisted of randomizing 72 medically controlled patients with PACG with cataract to either phacoemuslification alone (Group I, 35 patients) or to combined PKE with trabeculectomy with adjunctive Mitimycin C (Gro ...
week 13.: autoimmunity i.
week 13.: autoimmunity i.

... number of cells or tissues. AIRE ensures that these proteins are expressed in the thymus, where their peptide antigens contribute to negative selection of the T cell repertoire. In this case the normal array of tissue-specific proteins is not expressed in the thymus and hence negative selection of t ...
RRC_art 4.indd - Romanian Journal of Cardiology
RRC_art 4.indd - Romanian Journal of Cardiology

... of foam cells or to endothelial dysfunction47,48. Also, it has been revealed that persistently elevated erythrocyte sedimentation rate (ESR) is associated with the extension of atherosclerotic lesions49. PsA is also characterized by increased arterial stiffness through: reduced levels of endothelial ...
Factors Associated With Patient Delay in Heart Failure Patients
Factors Associated With Patient Delay in Heart Failure Patients

... Descriptive statistics were used to characterize the study population. Differences between patients with short and long patient delay were tested with Chi-square tests or Fisher’s exact tests for dichotomous variables and Mann-Whitney tests for continuous variables. A P-value < 0.05 (twotailed) was ...
Management of Extremity Lymphedema
Management of Extremity Lymphedema

... legs. A controlled site trial[18] of this type of pump followed 24 patients for six months following treatment and demonstrated that even after one treatment with the device, approximately half of the patients maintained most of their reduction over several months. The best results were seen in a pa ...
emergency medical treatment protocol
emergency medical treatment protocol

... Selegiline can ordinarily only be used safely without dietary restrictions at doses where it presumably selectively inhibits MAO B (e.g., 10 mg/day). In short, attention to the dose dependent nature of Selegiline's selectivity is critical if it is to be used without elaborate restrictions being plac ...
Slide 1
Slide 1

... 2. Partially uncontrolled 3. Uncontrolled ...
product monograph rescriptor
product monograph rescriptor

... controlled trials who received RESCRIPTOR 400 mg tid. Dose titration does not significantly reduce the incidence of rash. Skin rash is more common in patients with lower CD4 cell counts and typically occurs within 1 to 3 weeks of treatment. Severe and life threatening skin reactions have occurred on ...
Hepatic Encephalopathy: Diagnosis and Treatment
Hepatic Encephalopathy: Diagnosis and Treatment

... amino acid [BCAA]) and caused a deterioration in neurologic function.30 ...
Contrast Simulation Study Material
Contrast Simulation Study Material

...  Asthma may indicate an increased likelihood of a contrast reaction ...
A publicationof T he H imalaya D rug C ompany
A publicationof T he H imalaya D rug C ompany

... The Himalaya Drug Company was founded by my father in 1930, long before I was born, with a clear vision to bring Ayurveda to society in a contemporary form. New formulations were created by referring to ancient Ayurvedic texts, selecting widely available Indian herbs and subjecting dozens of these h ...
Development of structured treatment interruption strategies for HIV
Development of structured treatment interruption strategies for HIV

... and possible re-initiation, perhaps through several cycles of these steps. However, although STI regimens have been proposed based on experience and expert opinion and have been studied clinically in both humans and animals (Lisziewicz et al., 1999; Lori et al., 2000; Lori and Lisziewicz, 2001; Rose ...
Skin - The Dermatologist
Skin - The Dermatologist

... have a significant impact on the results of treatment regardless of what medications are prescribed. As we further come to understand the relationships between epidermal barrier function and specific underlying skin diseases, it becomes more apparent that proper skin care not only impacts tolerabili ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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