development of polymeric drug delivery systems for biotech products
... the field of drug delivery systems (DDSs). In this respect, many systems have been developed and conjugation with PEG (polyethylene glycol) can be considered one of the leading approaches. PEGylation brings to the conjugated molecule great solubility and stability to proteolytic digestion, furthermo ...
... the field of drug delivery systems (DDSs). In this respect, many systems have been developed and conjugation with PEG (polyethylene glycol) can be considered one of the leading approaches. PEGylation brings to the conjugated molecule great solubility and stability to proteolytic digestion, furthermo ...
The role of Arabidopsis CRK5 protein kinase in the regulation of root
... seven closely related members of the CRK family, the CRK5 kinase (At3g50530) carries an Nterminal MGxC myristylation/palmitoylation motive, which is conserved in all plasma membrane-associated CRK proteins examined so far in other plant species. The N-terminal domain of CRK5 also harbours a nuclear ...
... seven closely related members of the CRK family, the CRK5 kinase (At3g50530) carries an Nterminal MGxC myristylation/palmitoylation motive, which is conserved in all plasma membrane-associated CRK proteins examined so far in other plant species. The N-terminal domain of CRK5 also harbours a nuclear ...
The archaeal origins of the eukaryotic translational system
... assumed truly homologous among each phylodomain, for Bacteria and Archaea, for Eukarya and Archaea and for all three phylodomains. This was followed by full-sequence genome searches to ensure that apparent conserved patterns were truly characteristic of the various phylodomains over the widest possi ...
... assumed truly homologous among each phylodomain, for Bacteria and Archaea, for Eukarya and Archaea and for all three phylodomains. This was followed by full-sequence genome searches to ensure that apparent conserved patterns were truly characteristic of the various phylodomains over the widest possi ...
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... resistant TB strains, including strains with multiple drug resistance (MDR) and more recently, strains with extensive drug resistance (XDR). From the various MDR mechanisms, main focus is on efflux pumps as they contribute to MDR of Mycobacterium tuberculosis (MTB) in most of the cases. Efflux pumps ...
... resistant TB strains, including strains with multiple drug resistance (MDR) and more recently, strains with extensive drug resistance (XDR). From the various MDR mechanisms, main focus is on efflux pumps as they contribute to MDR of Mycobacterium tuberculosis (MTB) in most of the cases. Efflux pumps ...
Chapter 10
... Proteins can be translocated into the ER either during their synthesis on membrane-bound ribosomes (cotranslational translocation) or after their translation has been completed on free ribosomes in the cytosol (posttranslational translocation). In mammalian cells, most proteins enter the ER cotransl ...
... Proteins can be translocated into the ER either during their synthesis on membrane-bound ribosomes (cotranslational translocation) or after their translation has been completed on free ribosomes in the cytosol (posttranslational translocation). In mammalian cells, most proteins enter the ER cotransl ...
Additional file 1
... ATP binding cassette transporter putative (XP_002516304.1) Sugar transporter protein (NP_001191180.1) ...
... ATP binding cassette transporter putative (XP_002516304.1) Sugar transporter protein (NP_001191180.1) ...
Neutrophil-specific granule deficiency: homozygous recessive
... Since SGD individuals express normal levels of lactoferrin and ...
... Since SGD individuals express normal levels of lactoferrin and ...
Induction of CDPK (ZmCPK11)- and MAPK
... changes in the concentration of cytosolic and nuclear free calcium (Ca2+), referred to as calcium signature, are observed (Kudla et al. 2010). It has been shown that inhibitors of calcium channels affect negatively the expression of JA-induced genes (León et al. 1998, Sun et al. 2006). These results ...
... changes in the concentration of cytosolic and nuclear free calcium (Ca2+), referred to as calcium signature, are observed (Kudla et al. 2010). It has been shown that inhibitors of calcium channels affect negatively the expression of JA-induced genes (León et al. 1998, Sun et al. 2006). These results ...
Diapositive 1 - LBGI Bioinformatique et Génomique Intégratives
... Actin Related Proteins (ARPs) are key players in major biological processes important for cell life. In cytoskeleton activities, the ARP2/3 complex is essential for actin dynamics, ARP1 and ARP11 are involved in microtubule based vesicle trafficking, in nuclear functions (transcriptional activation, ...
... Actin Related Proteins (ARPs) are key players in major biological processes important for cell life. In cytoskeleton activities, the ARP2/3 complex is essential for actin dynamics, ARP1 and ARP11 are involved in microtubule based vesicle trafficking, in nuclear functions (transcriptional activation, ...
What are enzymes and how do they work
... a. The ribosome moves 1 nucleotide at a time b. The ribosome moves 2 nucleotides at a time c. The ribosome moves 3 nucleotides at a time 4. What is the next codon that will be read by the ribosome in the schematic above? ___GAA______ 5. What two features of a tRNA allow it to function as an “adapter ...
... a. The ribosome moves 1 nucleotide at a time b. The ribosome moves 2 nucleotides at a time c. The ribosome moves 3 nucleotides at a time 4. What is the next codon that will be read by the ribosome in the schematic above? ___GAA______ 5. What two features of a tRNA allow it to function as an “adapter ...
The topology of the proton translocating F0 component of the ATP
... (ii) The strain CM 2786-1 harboured the cloned atp operon on a plasmid and the membrane consequently contained 4- to 5- fold more ATP synthase than the wild-type. This strain was thus ideal for a study of the effects of proteases because the individual F 0 subunits could be easily recognized after S ...
... (ii) The strain CM 2786-1 harboured the cloned atp operon on a plasmid and the membrane consequently contained 4- to 5- fold more ATP synthase than the wild-type. This strain was thus ideal for a study of the effects of proteases because the individual F 0 subunits could be easily recognized after S ...
"Genetic Methods of Polymer Synthesis". In: Encyclopedia of
... Recombinant DNA methods have been traditionally used in site-directed mutagenesis studies designed to probe protein folding or enzymatic activity. The ease with which genetic sequences can be constructed has, however, led to the increased use of these methods for the synthesis of proteins with repet ...
... Recombinant DNA methods have been traditionally used in site-directed mutagenesis studies designed to probe protein folding or enzymatic activity. The ease with which genetic sequences can be constructed has, however, led to the increased use of these methods for the synthesis of proteins with repet ...
Cardiolipin-Mediated Mitochondrial Dynamics and
... them being linoleic acid [18:2 (n-6); Schlame et al., 2005]. This feature is rather unusual, because most other phospholipids, including CL’s precursor phosphatidylglycerol (PG), do not show an obvious preference for specific fatty acids. Although it is unknown how the acyl chain preference is determ ...
... them being linoleic acid [18:2 (n-6); Schlame et al., 2005]. This feature is rather unusual, because most other phospholipids, including CL’s precursor phosphatidylglycerol (PG), do not show an obvious preference for specific fatty acids. Although it is unknown how the acyl chain preference is determ ...
Chapter 13 Lecture Notes: Peptides, Proteins
... In addition to alpha helices and beta sheets, there are a few other, much less frequently seen geometries that are also categorized as secondary structures. Since these other secondary structures are relatively rare, I will not discuss their particularities. A key feature of secondary protein struct ...
... In addition to alpha helices and beta sheets, there are a few other, much less frequently seen geometries that are also categorized as secondary structures. Since these other secondary structures are relatively rare, I will not discuss their particularities. A key feature of secondary protein struct ...
Energy metabolism reactions in ruminant muscle: responses to
... and those of posture and activity. The metabolic reactions respond to a wide range of nutritional and hormonal stimuli and are often apparently co-ordinated; in magnitude, however, their contribution to energy requirements can be minor compared with locomotion and posture. Metabolic reactions includ ...
... and those of posture and activity. The metabolic reactions respond to a wide range of nutritional and hormonal stimuli and are often apparently co-ordinated; in magnitude, however, their contribution to energy requirements can be minor compared with locomotion and posture. Metabolic reactions includ ...
Regulation of Heat Shock Response in Yeast and - E
... 1.1. The role of HSF2 in developmental processes and heat shock response ............. 38 1.2 Regulation of HSF2 activation in hemin-induced K562 cells ................................ 38 1.3 Expression and function of HSF2 ........................................................................ 39 ...
... 1.1. The role of HSF2 in developmental processes and heat shock response ............. 38 1.2 Regulation of HSF2 activation in hemin-induced K562 cells ................................ 38 1.3 Expression and function of HSF2 ........................................................................ 39 ...
Engineering Tyrosine-Based Electron Flow Pathways in Proteins
... phenylalanines that can be selectively mutated to tyrosine residues, provides an ideal protein with which to study such through-protein electron transfer pathways and ways to manipulate them. Two surface exposed phenylalanines that are close to the heme have been mutated to tyrosines (F42Y, F98Y). I ...
... phenylalanines that can be selectively mutated to tyrosine residues, provides an ideal protein with which to study such through-protein electron transfer pathways and ways to manipulate them. Two surface exposed phenylalanines that are close to the heme have been mutated to tyrosines (F42Y, F98Y). I ...
Heterotrimeric G Protein–Coupled Signaling in Plants
... RGS proteins, and the Gβ subunit, as well as residues that form the guanine nucleotide-binding pocket and hydrolyze GTP (90). Most important for the explanation of why plant Gα subunits are self-activating, the nucleotide-binding pocket is located between these two domains (Figure 1c). The overall s ...
... RGS proteins, and the Gβ subunit, as well as residues that form the guanine nucleotide-binding pocket and hydrolyze GTP (90). Most important for the explanation of why plant Gα subunits are self-activating, the nucleotide-binding pocket is located between these two domains (Figure 1c). The overall s ...
Two glucose/xylose transporter genes from the yeast Candida
... fermentation of glucose-rich hydrolysates derived from dedicated agricultural crops (e.g. corn and wheat). However, the use of hemicellulosic materials as feedstock is deemed preferable both from an environmental and from an economic point of view because hemicellulose is a major component of low-va ...
... fermentation of glucose-rich hydrolysates derived from dedicated agricultural crops (e.g. corn and wheat). However, the use of hemicellulosic materials as feedstock is deemed preferable both from an environmental and from an economic point of view because hemicellulose is a major component of low-va ...
Template-Synthesized Protein Nanotubes
... is immersed first into a solution of 3-amino propylphosphonic acid (APA), resulting in attachment (again via the phosphonate) of a monolayer of this molecule to the pore walls. The amino groups are then reacted with an excess quantity of the protein-immobilization agent glutaraldehyde (GA),14,15 lea ...
... is immersed first into a solution of 3-amino propylphosphonic acid (APA), resulting in attachment (again via the phosphonate) of a monolayer of this molecule to the pore walls. The amino groups are then reacted with an excess quantity of the protein-immobilization agent glutaraldehyde (GA),14,15 lea ...
Ribosomal proteins L5 and L15 Ivailo Simoff in vivo
... proteins show high sequence homology across the species borders. Furthermore, both L5 and L15 are connected to various human diseases which makes it important to elucidate their role in ribosome biogenesis and ribosome function. By applying random- and site-directed mutagenesis, coupled with functio ...
... proteins show high sequence homology across the species borders. Furthermore, both L5 and L15 are connected to various human diseases which makes it important to elucidate their role in ribosome biogenesis and ribosome function. By applying random- and site-directed mutagenesis, coupled with functio ...
PDF - Oxford Academic - Oxford University Press
... of 3-week-old ara6 mutants at Zeitgeber time 3 (ZT3; Supplementary Fig. S2) because starch begins to accumulate at around this time point (McClung 2006, Seo et al. 2011) and we detected differences in the starch content at this time point most sensitively in the time course experiment. As a negative ...
... of 3-week-old ara6 mutants at Zeitgeber time 3 (ZT3; Supplementary Fig. S2) because starch begins to accumulate at around this time point (McClung 2006, Seo et al. 2011) and we detected differences in the starch content at this time point most sensitively in the time course experiment. As a negative ...
Directions: Choose the BEST answer from among those given.
... e) choose this answer if none of these is the best choice 22)A common structural motif of proteins in which a linear sequence of amino acids folds into a righthanded elongated structure that twists in regular corkscrew fashion around a central axis, and is stabilized by internal hydrogen bonding bet ...
... e) choose this answer if none of these is the best choice 22)A common structural motif of proteins in which a linear sequence of amino acids folds into a righthanded elongated structure that twists in regular corkscrew fashion around a central axis, and is stabilized by internal hydrogen bonding bet ...