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Proteins
Proteins

... • 8. Regulation: Certain proteins not only control the expression of genes, but also control when gene expression takes place. • Proteins are divided into two types: • Fibrous proteins • Globular proteins ...
Structural investigation of single biomolecules
Structural investigation of single biomolecules

... Structural investigation of single biomolecules NMR spectroscopy and X-ray crystallography are currently the most common techniques capable of determining the structures of biological macromolecules like proteins and nucleic acids at an atomic level of resolution. The atomic force microscope (AFM) i ...
MOVEMENT OF SUBSTANCES
MOVEMENT OF SUBSTANCES

... • Its means that only some substances can move across the plasma membrane freely while the others cannot • Two general factors that determine : I. size II. Polarity ...
Figure E Functional classification of crop proteins into COG
Figure E Functional classification of crop proteins into COG

... microbiome analyses, 6 pens/diet were first chosen. All other animals were used for other investigations. For metaproteomic analyses, 4 animals each from 2 pens/diets were randomly selected. Collected content of crop and ceca was homogenized on a pen basis yielding two crop and cecal samples per die ...
Outer dense fibre protein 2 (ODF2) is a self
Outer dense fibre protein 2 (ODF2) is a self

... tropomyosins and ODF3. In addition, ODF2 contains two leucine-zipper regions in the C-terminal half (Fig. 1A). In many proteins, the predicted coiled-coil segments lie in areas that are thought to play a functionally important role, for example, in mediation of oligomerization (Lupas et al., 1991). ...
Varicella-Zoster Virus Specifies a Thymidylate Synthetase
Varicella-Zoster Virus Specifies a Thymidylate Synthetase

... Most organisms contain separate genes for TS and dihydrofolate reductase (DHFR), which uses as a substrate one of the products generated by TS. In contrast, several protozoa, including L. major, specify a bifunctional protein containing a D H F R domain in the amino-terminal portion and a TS domain ...
Full Text
Full Text

... provides information about the potential functional or structural contributions of sequence motif residues. For structural examples of sequence motifs to be meaningful in comparison with proteins of unknown structure, it is assumed that conserved sequence motifs will generally have the same local 3D ...
Aquaporin JcPIP2 is Involved in Drought Responses in Jatropha
Aquaporin JcPIP2 is Involved in Drought Responses in Jatropha

... reading frame encoding a protein of 280 amino acids. The amino acid sequence showed 94% identity with Ricinus communis PIP. Injection of JcPIP2 complementary RNA into Xenopus oocytes increased 10-fold the osmotic water permeability of the oocytes. Immunodetection of JcPIP2 with anti-JcPIP2 antibody ...
6. Protein Folding
6. Protein Folding

... form. From a kinetic standpoint, cis‐trans proline isomerization is a very slow process that can prevent the progress of protein folding by trapping one or more proline residues crucial for folding in the non‐native isomer, especially when the native protein requires the cis isomer. • More prolines— ...
Gene Therapy Progress and Prospects: Viral trafficking
Gene Therapy Progress and Prospects: Viral trafficking

... virions bind the nuclear pore complex (NPC) and release their DNA genome into the nucleus (reviewed by Whittaker15) (Figure 3). This process, reconstituted in vitro, has been shown to be inhibited with antibodies to the NPC complex or against importin b. In this sytem, HSV binding of the NPC was dep ...
Pattern searches for the identification of putative lipoprotein genes in
Pattern searches for the identification of putative lipoprotein genes in

... evidence that a protein is lipidated in vivo. These included (1) metabolic labelling of the protein, in its source organism, with exogenously supplied radiolabelled fatty acid (normally palmitate, incorporation of which is typically detected by autoradiography following protein electrophoresis). Thi ...
Plant K Channel Proteins
Plant K Channel Proteins

... equation tells us that a membrane potential of this magnitude could allow for passive accumulation of K moving into cells through K channels to a level two orders of magnitude greater than external [K]. In fact, cytosolic K is typically 100-150 mM in plant cells (while K in the soil solution is ofte ...
Saccharomyces cerevisiae Elongator mutations confer resistance to
Saccharomyces cerevisiae Elongator mutations confer resistance to

TyrPhos12
TyrPhos12

... • Low-abundance proteins, their activation exerts major effects due to simultaneous activation of several signaling pathways that are often synergistic and  enhanced survival and growth. • This is an important function of growth factors when they are located on dendritic spines or shafts or on nerv ...
Structure and assembly of the spliceosomal small nuclear
Structure and assembly of the spliceosomal small nuclear

... used to investigate pairwise interactions of the Sm proteins [33•,34•]. Kambach et al. [32••] have been able to arrange all seven Sm proteins within a seven-membered ring (Figure 1d) in a manner that is consistent with all the known pairwise interactions [33•,34•]. The heptameric ring is the only co ...
Exploring Proteins - Weber State University
Exploring Proteins - Weber State University

... powerful analytical tools in biochemistry • An antibody (Immunoglobulin, Ig) is a complex protein formed by an animal in response to the presence of a foreign substance (most often foreign proteins). • An antibody usually exhibits specific and high affinity for their “antigens” that stimulated their ...
The Tobacco Homolog of Mammalian Calreticulin
The Tobacco Homolog of Mammalian Calreticulin

... or may be part of the structure of reticuloplasmin retention signals (Haugejorden et al., 1991; Denecke et al., 1992) and that retention cannot be predicted based on the primary sequence. This notion is illustrated by the fact that the auxin binding protein ABPl contains the KDEL motif but does not ...
sv-lncs - School of Mathematical and Computer Sciences
sv-lncs - School of Mathematical and Computer Sciences

... among the same set of proteins in a random graph. They observed that the majority of cliques (fully connected graphs) of size four or greater are statistically significant in PPI networks compared with random graphs. Hence, small cliques are likely to appear by chance. Also, we know that data obtain ...
Origin and evolution of peptide-modifying
Origin and evolution of peptide-modifying

... collagen-like proteins in bacteria. Jumonji-related domains diversified into three distinct lineages in bacterial secondary metabolism systems and these were precursors of the three major clades of ...
Reduced amino acid alphabets exhibit an improved sensitivity and
Reduced amino acid alphabets exhibit an improved sensitivity and

... Protein Data Bank (PDB), it is clear that the same protein fold may be generated by different amino acid sequences; in effect, the structure of proteins is more conserved than their sequences (Chothia and Lesk, 1986). In some cases, the sequences underlying similar structures show almost zero sequen ...
Plant, Cell and Environment
Plant, Cell and Environment

... acids, from the source leaf companion cells into the cells of different sink organs can follow the same symplastic pathways. Apoplastic transport of sucrose is unlikely to play a major role between the cells of these tissues. However, numerous cells and tissues are not symplastically connected to th ...
12.4 G Protein–Coupled Receptors and Second Messengers
12.4 G Protein–Coupled Receptors and Second Messengers

Cloning, sequence and in vitro transcription/translation analysis of a
Cloning, sequence and in vitro transcription/translation analysis of a

Nitrogen lectures (Part 2)
Nitrogen lectures (Part 2)

... FACTORS AFFECTING PROTEIN REQUIREMENTS ...
lecture08_11
lecture08_11

... – Detect similar function where sequence differs (only ~50% remote homologies can be detected based on sequence) ...
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Magnesium transporter

This page links directly from the magnesium in biological systems page.Magnesium transporters are proteins that transport magnesium across the cell membrane. All forms of life require magnesium, yet the molecular mechanisms of Mg2+ uptake from the environment and the distribution of this vital element within the organism are only slowly being elucidated.In bacteria, Mg2+ is probably mainly supplied by the CorA protein and, where the CorA protein is absent, by the MgtE protein. In yeast the initial uptake is via the Alr1p and Alr2p proteins, but at this stage the only internal Mg2+ distributing protein identified is Mrs2p. Within the protozoa only one Mg2+ transporter (XntAp) has been identified. In metazoa, Mrs2p and MgtE homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been identified along with another novel protein, AtMHX.
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