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Functional Characterization of a Mitochondrial Ser/Thr Protein
Functional Characterization of a Mitochondrial Ser/Thr Protein

... Protein phosphorylation is a major form of posttranslational modification critical to cell signaling that also occurs in mitochondrial proteome. Yet, only very limited studies have been performed to characterize mitochondrial-targeted protein kinases or phosphatases. Recently, we identified a novel ...


... 3. Which of the following is most correct: a) Charged amino acids are never buried in the interior of a protein. b) All hydrophobic amino acids are buried when a protein folds. c) Tyrosine is only found in the interior of proteins. d) Glycine is rarely found in proteins because it is too destabilizi ...
Chapter 3 - Slothnet
Chapter 3 - Slothnet

... from hydrogen bonding between N–H groups on one amino acid and C=O groups on another. • β pleated sheet—two or more polypeptide chains are aligned; hydrogen bonds form between the chains. ...
Functional protein micropatterning for drug design
Functional protein micropatterning for drug design

Amino acid catabolism I
Amino acid catabolism I

... transdeamination (transamination+GDH) minor patways 2. deamination of other compounds N-containing side chains of nucleotides neurotransmitters 3. ammonia production in the large intestine by bacteria portal vein, direct transport of ammonia. Urea cycle Function: 1. prevents ammonia levels from risi ...
The following equations and constants may be useful:
The following equations and constants may be useful:

... surfaces at low pH values (e.g. pH < 6). However, its adherence properties become progressively weaker as the pH is raised. ...
Interaction interfaces of protein domains are not topologically
Interaction interfaces of protein domains are not topologically

... involved in binding to other proteins are better conserved than the other residues.9,10 Evolutionary information derived from the large number of protein sequences and structures can powerfully guide both the analysis and prediction of protein–protein interfaces. The residue conservation at the inte ...
It Works! Shake™ Product Info Sheet
It Works! Shake™ Product Info Sheet

... Yellow Pea and Organic Sprouted Brown Rice proteins. This “perfect protein” blend contains a balanced amino acid profile. What does that mean? These two proteins complement each other, with the Organic Sprouted Brown Rice protein providing a complete spectrum of amino acids, including being high in ...
The Effect of Protein Loads on Plasma Amino Acid Levels
The Effect of Protein Loads on Plasma Amino Acid Levels

Targeted Quantitation of HMGB1 Protein by label
Targeted Quantitation of HMGB1 Protein by label

No Slide Title
No Slide Title

... O-Mannose •UDP-Glc Transfers Glc1-P to Mannose on a cystosolic protein •62kD protein is Phosphoglucomutase (Glc-1-PGlc-6-P) •Transferase and phosphodiesterase found on many cells •Membrane association regulated by modification with Glc-1-P •Structure of underlying oligosaccharide not known ...
Exam 2
Exam 2

... (b) (2 pts) A b-specific nuclease catalyzes the hydrolysis of pApGpCpTp between the C and T residues. Write the products of this cleavage reaction using the same nomenclature. (c) (2 pts) What two amino acid residues are somewhat more likely to be part of a tight beta turn in a protein structure? (d ...
Molecular Reaction Mechanisms of Proteins
Molecular Reaction Mechanisms of Proteins

cAMP-Dependent Protein Kinase, Catalytic Subunit Product
cAMP-Dependent Protein Kinase, Catalytic Subunit Product

pdf file
pdf file

... and the plasma membrane. Here, we report the identification of COD1/SPF1 (control of HMGCoA reductase degradation/SPF1) through genetic strategies intended to uncover genes involved in protein maturation and endoplasmic reticulum (ER)-associated degradation (ERAD), a quality control pathway that rid ...
Protein Synthesis, Processing, and Regulation
Protein Synthesis, Processing, and Regulation

... together and, under appropriate conditions, will reform a functional ribosome. Although ribosome assembly in vivo (particularly in eukaryotic cells) is considerably more complicated, the ability of ribosomes to self-assemble in vitro has provided an important experimental tool, allowing analysis of ...
Gene Expression and Signal Transduction
Gene Expression and Signal Transduction

... of multiple copies of certain genes, or multigene families. The best-studied plant genome is that of A. thaliana. Arabidopsis contains roughly 26,000 genes, approximately the same number as in the human genome. In contrast, the rice (Oryza sativa) genome has been estimated to contain between 35,000 ...
Mitochondrial quality control by the ubiquitin
Mitochondrial quality control by the ubiquitin

... an ERAD-like system, MAD, has been proposed to operate at mitochondria [10–12,14,15]. In this system, matrix or inner membrane proteins are retrotranslocated to the outer membrane for ubiquitination and targeting to the proteasome. Several observations support the existence of such a system. Protein ...
The Possible DNA-binding Nature of the Regulatory Proteins
The Possible DNA-binding Nature of the Regulatory Proteins

... the first two of these stages (0 and I) have, in fact, nothing to do with the developmental process and can be disregarded as far as this paper is concerned. For the molecular biologist the questions posed are those that arise in any study of differentiation. (a) How many operons - gene clusters fun ...
Mass spectrometry and the search for moonlighting proteins
Mass spectrometry and the search for moonlighting proteins

... found in multiple locations: inside and outside of cells, within different cell types, in different locations within a cell, within different protein complexes, and with different binding partners (Fig. 2). However, although moonlighting proteins can complicate the interpretation of the results of t ...
The following equations and constants may be useful:
The following equations and constants may be useful:

... surfaces at low pH values (e.g. pH < 6). However, its adherence properties become progressively weaker as the pH is raised. ...
The Logic Linking Protein Acetylation and Metabolism
The Logic Linking Protein Acetylation and Metabolism

On the trail of protein sequences
On the trail of protein sequences

... notions are dangerous in science, although they’re usually easier to spot in others. The project was worthwhile on several fronts, and we learned a good deal about computing and sequence comparison both, even though we were operating under severe constraints. The PDP-11 had a hard disk with a maximu ...
The Plant Cell - College of Computer, Mathematical, and Natural
The Plant Cell - College of Computer, Mathematical, and Natural

... Turgeon, 1999, in this issue). Interestingly, AHA9 and AHA10 are expressed specifically in the anther (Houlne and Boutry, 1994) and the developing seed (Harper et al., 1994), respectively. Pumps in the root epidermis are thus thought to function mainly in energizing nutrient uptake from the soil, wh ...
Crystal Structure of 4-Chlorobenzoate:CoA Ligase/Synthetase in the
Crystal Structure of 4-Chlorobenzoate:CoA Ligase/Synthetase in the

... thiol on the mixed anhydride to form the CoA thioester (k ) 100 s-1). CBAL is a member of the adenylate-forming enzyme superfamily (6). The enzymes are 500-700 residues in length and are usually soluble however membrane-bound proteins have also been identified that are involved in fatty-acid uptake ...
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Magnesium transporter

This page links directly from the magnesium in biological systems page.Magnesium transporters are proteins that transport magnesium across the cell membrane. All forms of life require magnesium, yet the molecular mechanisms of Mg2+ uptake from the environment and the distribution of this vital element within the organism are only slowly being elucidated.In bacteria, Mg2+ is probably mainly supplied by the CorA protein and, where the CorA protein is absent, by the MgtE protein. In yeast the initial uptake is via the Alr1p and Alr2p proteins, but at this stage the only internal Mg2+ distributing protein identified is Mrs2p. Within the protozoa only one Mg2+ transporter (XntAp) has been identified. In metazoa, Mrs2p and MgtE homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been identified along with another novel protein, AtMHX.
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