FEBS Letters
... as a potential confounding phenomenon in the assessment of low affinity transport kinetics [7]. Tester and Davenport [1] also pointed out that the high rates of influx measured with tracers match well with the magnitude of sodium inward currents measured in protoplasts isolated from roots. As stated ea ...
... as a potential confounding phenomenon in the assessment of low affinity transport kinetics [7]. Tester and Davenport [1] also pointed out that the high rates of influx measured with tracers match well with the magnitude of sodium inward currents measured in protoplasts isolated from roots. As stated ea ...
Human Diseases Associated with Form and Function of the Golgi
... the mutation found in Dyggve-Melchior-Clausen disease occurs at a lysine residue that is conserved in RAB33B orthologs across all species [41]. In fact, this lysine residue is found in the GTP binding pocket of all Rab family members thereby demonstrating the importance of this residue to the functi ...
... the mutation found in Dyggve-Melchior-Clausen disease occurs at a lysine residue that is conserved in RAB33B orthologs across all species [41]. In fact, this lysine residue is found in the GTP binding pocket of all Rab family members thereby demonstrating the importance of this residue to the functi ...
Heart Failure
... (microtubule-associated protein 1 light chain 3), an 18-kDa homologue of Atg8 in yeast, is processed and lipid conjugated.18 The resulting 16-kDa active isoform migrates from the cytoplasm to isolation membranes and autophagosomes. Recently, intracellular migration of LC3 to vesicular membranes has ...
... (microtubule-associated protein 1 light chain 3), an 18-kDa homologue of Atg8 in yeast, is processed and lipid conjugated.18 The resulting 16-kDa active isoform migrates from the cytoplasm to isolation membranes and autophagosomes. Recently, intracellular migration of LC3 to vesicular membranes has ...
Fig. 1 - The Journal of Cell Biology
... Tim50 is the major presequence receptor of the TIM23 complex in the inner mitochondrial membrane and regulates gating of the Tim23 pore. A surprising and still unresolved observation is that a loss of Tim50 leads to robust import defects for matrix proteins, but has a much lesser effect on precursor ...
... Tim50 is the major presequence receptor of the TIM23 complex in the inner mitochondrial membrane and regulates gating of the Tim23 pore. A surprising and still unresolved observation is that a loss of Tim50 leads to robust import defects for matrix proteins, but has a much lesser effect on precursor ...
Plant Vacuoles
... 1996; Müntz, 1998; see Herman and Larkins, 1999, in this issue). The membrane of the protein storage vacuoles (PSVs) contains the seed-specific aquaporin a-TIP (Höfte et al., 1992; Paris et al., 1996; Swanson et al., 1998; see below). Storage proteins are also synthesized and accumulated in speciali ...
... 1996; Müntz, 1998; see Herman and Larkins, 1999, in this issue). The membrane of the protein storage vacuoles (PSVs) contains the seed-specific aquaporin a-TIP (Höfte et al., 1992; Paris et al., 1996; Swanson et al., 1998; see below). Storage proteins are also synthesized and accumulated in speciali ...
High pressure effects on protein structure and function
... It is generally accepted that formation of hydrosome earlier indirect observations. The main-chain phobic contacts proceeds with positive AV values angles of helices and sheets are least affected by pressure, followed by the remaining main chains, and is therefore disfavored by pressure. Depending s ...
... It is generally accepted that formation of hydrosome earlier indirect observations. The main-chain phobic contacts proceeds with positive AV values angles of helices and sheets are least affected by pressure, followed by the remaining main chains, and is therefore disfavored by pressure. Depending s ...
Plant Vacuoles
... 1996; Müntz, 1998; see Herman and Larkins, 1999, in this issue). The membrane of the protein storage vacuoles (PSVs) contains the seed-specific aquaporin a-TIP (Höfte et al., 1992; Paris et al., 1996; Swanson et al., 1998; see below). Storage proteins are also synthesized and accumulated in speciali ...
... 1996; Müntz, 1998; see Herman and Larkins, 1999, in this issue). The membrane of the protein storage vacuoles (PSVs) contains the seed-specific aquaporin a-TIP (Höfte et al., 1992; Paris et al., 1996; Swanson et al., 1998; see below). Storage proteins are also synthesized and accumulated in speciali ...
Identification of a Protein with Antioxidant Activity that is Important for
... Biosciences, NJ, USA). a kDa ...
... Biosciences, NJ, USA). a kDa ...
COMBINATION COMPRISING AT LEAST ONE AMINO ACID AND A
... arachadonic acid, which is then metabolized to prostaglandins and 15-hydroxyeicosatetraenoic acid (15-HETE). 15HETE has been shown to produce a significant increase in protein degradation and nuclear binding of the transcription factor NF-κB (a nuclear factor that binds the kappa immunoglobulin ligh ...
... arachadonic acid, which is then metabolized to prostaglandins and 15-hydroxyeicosatetraenoic acid (15-HETE). 15HETE has been shown to produce a significant increase in protein degradation and nuclear binding of the transcription factor NF-κB (a nuclear factor that binds the kappa immunoglobulin ligh ...
Genome-wide Screen for Inner Nuclear Membrane
... below and then the mutant regions were exchanged with the corresponding fragment of pRS415TRM1-II-GFP. pRS415-TRM1-II-∆L2-GFP contains a deletion of the TRM1-II second codon. It was generated by reverse PCR using pGEMT-A1-4 as the template. pRS415-TRM1-II-K3→E3GFP and pRS415-TRM1-II-L2→F2 were obtai ...
... below and then the mutant regions were exchanged with the corresponding fragment of pRS415TRM1-II-GFP. pRS415-TRM1-II-∆L2-GFP contains a deletion of the TRM1-II second codon. It was generated by reverse PCR using pGEMT-A1-4 as the template. pRS415-TRM1-II-K3→E3GFP and pRS415-TRM1-II-L2→F2 were obtai ...
Effects of phosphatidylethanolamine glycation on lipid–protein
... glycation by forming adducts with PE. Moreover, these authors found these complexes in human red blood cells, suggesting that this compound may act as a lipid glycation inhibitor in vivo, and demonstrated that supplementation of the diet of diabetic rats with pyridoxal 5 -phosphate reduces the leve ...
... glycation by forming adducts with PE. Moreover, these authors found these complexes in human red blood cells, suggesting that this compound may act as a lipid glycation inhibitor in vivo, and demonstrated that supplementation of the diet of diabetic rats with pyridoxal 5 -phosphate reduces the leve ...
Phloem RNA-binding proteins as potential components of the long
... vitro (Gómez and Pallás, 2001; Owens et al., 2001). The lectins belonging to the PP2 family are among the most abundant and enigmatic proteins in phloem sap. Moreover the phylogeny analyses identified PP2-like genes in species from 17 angiosperm and gymnosperm genera, and indicated that these protein ...
... vitro (Gómez and Pallás, 2001; Owens et al., 2001). The lectins belonging to the PP2 family are among the most abundant and enigmatic proteins in phloem sap. Moreover the phylogeny analyses identified PP2-like genes in species from 17 angiosperm and gymnosperm genera, and indicated that these protein ...
Self-Subunit Swapping Occurs in Another Gene Type of Cobalt
... of metal ions into NHases is mediated by various ‘‘activator proteins’’ [1]. Fe-NHases require activators for functional expression in Rhodococcus sp. N-771 [24], Pseudomonas chlororaphis B23 [25], and Rhodococcus sp. N-774 [26]. A proposed metal-binding motif, CXCC, in the NHase activator of Rhodoc ...
... of metal ions into NHases is mediated by various ‘‘activator proteins’’ [1]. Fe-NHases require activators for functional expression in Rhodococcus sp. N-771 [24], Pseudomonas chlororaphis B23 [25], and Rhodococcus sp. N-774 [26]. A proposed metal-binding motif, CXCC, in the NHase activator of Rhodoc ...
Identification of proteins that putatively bind the
... SCRM or SCRM2 cause the excess production of entry division resulting higher density and clustered stomata. A combination of a scrm-D mutation with a spch, mute, or fama mutation produces an additive phenotype (Kanaoka et al., 2008). The epidermis of mute has normal pavement cells and excessively a ...
... SCRM or SCRM2 cause the excess production of entry division resulting higher density and clustered stomata. A combination of a scrm-D mutation with a spch, mute, or fama mutation produces an additive phenotype (Kanaoka et al., 2008). The epidermis of mute has normal pavement cells and excessively a ...
Roles of phosphatidate phosphatase enzymes in lipid metabolism
... protein kinase C [15–17]. In addition, PAP activity can attenuate the bioactive functions of PtdOH, which include promoting cell growth and proliferation, vesicular trafficking, secretion and endocytosis [5,8,17–20]. PAP1 PAP1 enzymes have been purified and characterized from the membrane and cytoso ...
... protein kinase C [15–17]. In addition, PAP activity can attenuate the bioactive functions of PtdOH, which include promoting cell growth and proliferation, vesicular trafficking, secretion and endocytosis [5,8,17–20]. PAP1 PAP1 enzymes have been purified and characterized from the membrane and cytoso ...
implications of protein flexibility for drug discovery
... different substrate affinities, can be modulated by binding at these sites, which are remote from the active site2. From a thermodynamic standpoint, the induced-fit and conformational-selection models are equivalent. However, the concepts of conformational selection and induction are more useful whe ...
... different substrate affinities, can be modulated by binding at these sites, which are remote from the active site2. From a thermodynamic standpoint, the induced-fit and conformational-selection models are equivalent. However, the concepts of conformational selection and induction are more useful whe ...
Expression and V (D) J recombination activity of mutated RAG
... immune system. Little is known of the specific role these genes play. We have explored the sequences encoding mouse RAG-1 by deleting large parts of the gene and by introducing local sequence changes. We find that a RAG-1 gene with 40% of the coding region deleted still retains its recombination fun ...
... immune system. Little is known of the specific role these genes play. We have explored the sequences encoding mouse RAG-1 by deleting large parts of the gene and by introducing local sequence changes. We find that a RAG-1 gene with 40% of the coding region deleted still retains its recombination fun ...
Review Common Themes in Mechanisms of Gene Silencing
... at least two types of silencing complexes, discussed below, these mechanisms involve the physical coupling of histone modifying enzymes to histone binding proteins. SIR-Mediated Gene Silencing in Budding Yeast One of the best-studied examples of eukaryotic gene silencing occurs in the budding yeast ...
... at least two types of silencing complexes, discussed below, these mechanisms involve the physical coupling of histone modifying enzymes to histone binding proteins. SIR-Mediated Gene Silencing in Budding Yeast One of the best-studied examples of eukaryotic gene silencing occurs in the budding yeast ...
Vitamin supplementation by gut symbionts ensures metabolic
... Figure 2. Pairwise MA plots for expressed genes among aposymbiotic and symbiotic D. fasciatus reared on their natural diet of cottonseeds. The scatter plot depicts the distribution of aposymbiotic/symbiotic log2 intensity ratio (M-value) versus the log2 average intensity (A-value). Each dot represen ...
... Figure 2. Pairwise MA plots for expressed genes among aposymbiotic and symbiotic D. fasciatus reared on their natural diet of cottonseeds. The scatter plot depicts the distribution of aposymbiotic/symbiotic log2 intensity ratio (M-value) versus the log2 average intensity (A-value). Each dot represen ...
MB ChB PHASE I
... into mucosal cells by several methods, including ATP-driven Na+-dependent transport like that used for Glc. [Energy Transformations - Carbohydrates Lecture 2] ...
... into mucosal cells by several methods, including ATP-driven Na+-dependent transport like that used for Glc. [Energy Transformations - Carbohydrates Lecture 2] ...
Document
... certain molecular groups result in absorption bands at specific spectral positions, both respond to the coupling to the environment, and both allow one to determine connectivity of molecular groups and thereby ultimately the 3D structure of a molecule by employing multidimensional techniques [1–3]. ...
... certain molecular groups result in absorption bands at specific spectral positions, both respond to the coupling to the environment, and both allow one to determine connectivity of molecular groups and thereby ultimately the 3D structure of a molecule by employing multidimensional techniques [1–3]. ...
lecture 8
... GroEL function: single polypeptide N- and C-termini of GroEL (chaperonins in general) are buried inside the cavity construct is a fusion between all 7 subunits--protein size is ...
... GroEL function: single polypeptide N- and C-termini of GroEL (chaperonins in general) are buried inside the cavity construct is a fusion between all 7 subunits--protein size is ...
Bio-fermentation Technology to Improve Efficiency of Swine Nutrition*
... diets, thereby improving nutrient utilization and reducing nutrient excretion to the environment. Yeast metabolites are also produced by bio-fermentation and have been repeatedly shown to improve milk production of sows during early lactation even though actual mechanisms are still to be investigate ...
... diets, thereby improving nutrient utilization and reducing nutrient excretion to the environment. Yeast metabolites are also produced by bio-fermentation and have been repeatedly shown to improve milk production of sows during early lactation even though actual mechanisms are still to be investigate ...
The water of life: osmoregulation in Saccharomyces cerevisiae
... Interactions between the target of rapamycin (TOR) and the CWI pathways during nutrient stress, and effects on osmotolerance ...
... Interactions between the target of rapamycin (TOR) and the CWI pathways during nutrient stress, and effects on osmotolerance ...
Common infection strategies of plant and animal pathogenic bacteria
... Once the bacteria are close to a host cell, they start to inject effector proteins into the cytosol of the eukaryotic ...
... Once the bacteria are close to a host cell, they start to inject effector proteins into the cytosol of the eukaryotic ...