Mechanisms of Therapeutic Actions and Adverse Side Effects
... Each atypical antipsychotic agent has a binding profile that differs from other antipsychotics. An antipsychotic’s binding profile is a summation of the receptors to which it binds, the strength of the binding to individual receptor types (binding affinity or Ki), and the action of the drug on that ...
... Each atypical antipsychotic agent has a binding profile that differs from other antipsychotics. An antipsychotic’s binding profile is a summation of the receptors to which it binds, the strength of the binding to individual receptor types (binding affinity or Ki), and the action of the drug on that ...
street drugs and alcohol
... • sensory effects – e.g. tinnitus, giddiness, blurred vision • physical – e.g. exhaustion, twitching, aches and pains • extreme – e.g. delirium, convulsion and even death! ...
... • sensory effects – e.g. tinnitus, giddiness, blurred vision • physical – e.g. exhaustion, twitching, aches and pains • extreme – e.g. delirium, convulsion and even death! ...
Lecture 3 – intro to ANS drugs – cholinergic
... monoamine transporter) ▪ Blocked by drug reserpine = depletion of adrenergic stores ...
... monoamine transporter) ▪ Blocked by drug reserpine = depletion of adrenergic stores ...
Introduction to Autonomic Drugs: Cholinergic agents
... monoamine transporter) ▪ Blocked by drug reserpine = depletion of adrenergic stores ...
... monoamine transporter) ▪ Blocked by drug reserpine = depletion of adrenergic stores ...
Boost Your Mood Class Recording - Philadelphia Integrative Medicine
... – Most behavior and personality is influenced by many genes – There are no individual genes for mental disorders – In general – our psychological make-up is heritable up to 50% ...
... – Most behavior and personality is influenced by many genes – There are no individual genes for mental disorders – In general – our psychological make-up is heritable up to 50% ...
Drug Facts Sheet Amphetamines
... Effect on mind The effects of amphetamines and methamphetamine are similar to cocaine, but their onset is slower and their duration is longer. In contrast to cocaine, which is quickly removed from the brain and is almost completely metabolized, methamphetamine remains in the central nervous system l ...
... Effect on mind The effects of amphetamines and methamphetamine are similar to cocaine, but their onset is slower and their duration is longer. In contrast to cocaine, which is quickly removed from the brain and is almost completely metabolized, methamphetamine remains in the central nervous system l ...
Mechanisms of common and important adverse drug reactions
... Mechanisms of common and important adverse drug reactions Jack W. Strandhoy, Ph.D. ...
... Mechanisms of common and important adverse drug reactions Jack W. Strandhoy, Ph.D. ...
ISHIK UNIVERSITY FACULTY OF DENTISTRY
... Pharmacodynamics governs the concentrationeffect part of the interaction, whereas pharmacokinetics deals with the doseconcentration part. The pharmacokinetic processes of absorption, distribution, and elimination determine how rapidly and for how long the drug will appear at the target organ. The ph ...
... Pharmacodynamics governs the concentrationeffect part of the interaction, whereas pharmacokinetics deals with the doseconcentration part. The pharmacokinetic processes of absorption, distribution, and elimination determine how rapidly and for how long the drug will appear at the target organ. The ph ...
Medicinal Chemistry (MDCH) 5220
... Considering the biochemical processes occurring in neurons, what might be targets for drug action? [i.e. that Goodman & Gilman table from Monday’s adrenergic lecture & the pictures of neurons and biochemical pathways in the notes]. Think of example drugs that modulate these processes at various stag ...
... Considering the biochemical processes occurring in neurons, what might be targets for drug action? [i.e. that Goodman & Gilman table from Monday’s adrenergic lecture & the pictures of neurons and biochemical pathways in the notes]. Think of example drugs that modulate these processes at various stag ...
receptors
... Large and prolonged intake of certain substances cause an increase in the number of receptors (basis of withdrawal response in addiction). Each NT influences its own receptors independent of the action of other receptors. Excitatory and inhibitory NTs. Post-synaptic neuron sums up the influences of ...
... Large and prolonged intake of certain substances cause an increase in the number of receptors (basis of withdrawal response in addiction). Each NT influences its own receptors independent of the action of other receptors. Excitatory and inhibitory NTs. Post-synaptic neuron sums up the influences of ...
C22L3 PPT - Destiny High School
... Crack, also called rock or freebase rock, reaches the brain seconds after being smoked or injected. Once in the blood, crack causes the heart rate and blood pressure to soar to dangerous levels. ...
... Crack, also called rock or freebase rock, reaches the brain seconds after being smoked or injected. Once in the blood, crack causes the heart rate and blood pressure to soar to dangerous levels. ...
Psychoactive Drugs Notes
... Drugs and altered consciousness Psychoactive drugs: drugs that affect the brain and change consciousness How do they work? drugs change the way our neurotransmitters work neurotransmitter: chemicals that neurons use to communicate with each other ...
... Drugs and altered consciousness Psychoactive drugs: drugs that affect the brain and change consciousness How do they work? drugs change the way our neurotransmitters work neurotransmitter: chemicals that neurons use to communicate with each other ...
镇静催眠药sedative-hypnotic drugs
... the frequency of C1－ channel openness . It is generally believed that GABAA receptors in amygdala and cornu ammonis play a role in antianxiety of BZ ，while the sedation and hypnosis effect is related to receptors in the brain stem. ...
... the frequency of C1－ channel openness . It is generally believed that GABAA receptors in amygdala and cornu ammonis play a role in antianxiety of BZ ，while the sedation and hypnosis effect is related to receptors in the brain stem. ...
NOOTROPIC DRUGS
... ACTION • TCAs inhibit serotonin, norepinephrine, and dopamine transporters, slowing reuptake • TCAs also allow for the down regulation of post-synaptic receptors • All TCAs and SSRIs contain an essential amino group that appears to interact with Asp98 in hSERT ...
... ACTION • TCAs inhibit serotonin, norepinephrine, and dopamine transporters, slowing reuptake • TCAs also allow for the down regulation of post-synaptic receptors • All TCAs and SSRIs contain an essential amino group that appears to interact with Asp98 in hSERT ...
29.5 Brain Function and Chemistry
... • Different neurotransmitters relate to different functions. synapse ...
... • Different neurotransmitters relate to different functions. synapse ...
29.5 Brain Function and Chemistry KEY CONCEPT brain.
... • Different neurotransmitters relate to different functions. synapse ...
... • Different neurotransmitters relate to different functions. synapse ...
drug abuse - Leduc Victim Services
... central to a person’s thoughts, emotions and activities that they cannot stop using it. Tolerance: With regular use, a user needs more and more of a drug to get the same effect. Overdose: May or may not be fatal. May occur in users who have developed a tolerance for a drug, or street drug users who ...
... central to a person’s thoughts, emotions and activities that they cannot stop using it. Tolerance: With regular use, a user needs more and more of a drug to get the same effect. Overdose: May or may not be fatal. May occur in users who have developed a tolerance for a drug, or street drug users who ...
Insight therapies
... Modify irrational self-talk, set attainable behavioral goals and develop realistic strategies for attaining them ...
... Modify irrational self-talk, set attainable behavioral goals and develop realistic strategies for attaining them ...
Routes of Excretion
... ◦ 2nd messenger systems ◦ more than 50 G protein coupled receptors have been identified ◦ control many cellular processes ...
... ◦ 2nd messenger systems ◦ more than 50 G protein coupled receptors have been identified ◦ control many cellular processes ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.