Pharmacology 3a – Cholinomimetics
... A cholinomimetic drug is one that mimics the action of acetylcholine. They are clinically important because they act on post-ganglionic muscarinic receptors. s NB: ACh is of no therapeutic use as it does not differentiate between nicotinic and muscarinic receptors and is rapidly degraded Nicotin ...
... A cholinomimetic drug is one that mimics the action of acetylcholine. They are clinically important because they act on post-ganglionic muscarinic receptors. s NB: ACh is of no therapeutic use as it does not differentiate between nicotinic and muscarinic receptors and is rapidly degraded Nicotin ...
PAUL O. OCHIENG`
... and the evolving legal models, policies and propositions on regulation of controlled drugs in Kenya and also analyzed the measures that have been taken to regulate and control the use of controlled drugs in the country. Methodology: This research involved a systematic and contemplative analysis of K ...
... and the evolving legal models, policies and propositions on regulation of controlled drugs in Kenya and also analyzed the measures that have been taken to regulate and control the use of controlled drugs in the country. Methodology: This research involved a systematic and contemplative analysis of K ...
1 Background The Federal Food, Drug and Cosmetic Act
... with the European Medicines Agency, all the data they have been collecting on almost 200 compounds over the past 20–30 years from these two-year rat cancer studies along with the results of shorter rat toxicology studies that are run for six-months to support clinical trial safety. These data indica ...
... with the European Medicines Agency, all the data they have been collecting on almost 200 compounds over the past 20–30 years from these two-year rat cancer studies along with the results of shorter rat toxicology studies that are run for six-months to support clinical trial safety. These data indica ...
Liam Watson (MSc, BSc (Hons.), PGDip.)
... time ‘just one more line – then I’ll quit.' I'll go for a piss it will be a tablespoon's worth. I'll piss out slugs of blood, like congealed jelly and the pain is horrific. It feels like a ball with loads of spikes just bouncing on your bladder. On a bad day I’ll go to the ...
... time ‘just one more line – then I’ll quit.' I'll go for a piss it will be a tablespoon's worth. I'll piss out slugs of blood, like congealed jelly and the pain is horrific. It feels like a ball with loads of spikes just bouncing on your bladder. On a bad day I’ll go to the ...
07.States_of_Consciousness
... • Our brain is protected by a layer of capillaries called the blood-brain barrier. • The drugs that are small enough to pass through are called psychoactive drugs. ...
... • Our brain is protected by a layer of capillaries called the blood-brain barrier. • The drugs that are small enough to pass through are called psychoactive drugs. ...
Toxidromes - Lakeridge Health
... reveal a clear blue sky and with it, a promise of another hot August day. In a back alley in south Oshawa, an EMS crew is just arriving to deal with a patient who is unresponsive and barely breathing. A troubled upbringing has lead down a path of drug abuse. This morning it has gone too far and the ...
... reveal a clear blue sky and with it, a promise of another hot August day. In a back alley in south Oshawa, an EMS crew is just arriving to deal with a patient who is unresponsive and barely breathing. A troubled upbringing has lead down a path of drug abuse. This morning it has gone too far and the ...
VISUAL ALTERATION
... HOW DO THESE TREAT GLAUCOMA? EXAMPLES OF DRUGS: -Latanoprost (Xalatan) -bimatoprost (Lumigan) -travoprost (Travatan): not to be used with pregnancy ...
... HOW DO THESE TREAT GLAUCOMA? EXAMPLES OF DRUGS: -Latanoprost (Xalatan) -bimatoprost (Lumigan) -travoprost (Travatan): not to be used with pregnancy ...
Pay Attention: Ritalin Acts Much Like Cocaine
... Methylphenidate flips the relationship, upping the signal and reducing the noise. After someone swallows methylphenidate, it enters the bloodstream and eventually finds the brain, where it blocks dopamine transporters and increases attention signaling. Again, cocaine acts the same way. But the two d ...
... Methylphenidate flips the relationship, upping the signal and reducing the noise. After someone swallows methylphenidate, it enters the bloodstream and eventually finds the brain, where it blocks dopamine transporters and increases attention signaling. Again, cocaine acts the same way. But the two d ...
pharm 24 [4-20
... High dose: alpha stim causes vasoconstriction and increased afterload (acceptable) Used for cardiac arrest [once again work upwards] 12. When do we use NE for heart conditions? Don’t. It’s fine for shock though 13. What is the synthetic β (mostly β1 and chronotropic) agonist? isoproterenol 1 ...
... High dose: alpha stim causes vasoconstriction and increased afterload (acceptable) Used for cardiac arrest [once again work upwards] 12. When do we use NE for heart conditions? Don’t. It’s fine for shock though 13. What is the synthetic β (mostly β1 and chronotropic) agonist? isoproterenol 1 ...
Side Effects of Sleep Drugs
... up to two weeks to help relieve occasional sleepiness in people ages 12 and older. "If you continue to have sleeping problems beyond two weeks, you should see a doctor," says Marina Chang, R.Ph., pharmacist and team leader in FDA's Division of Nonprescription Regulation Development. OTC sleep aids a ...
... up to two weeks to help relieve occasional sleepiness in people ages 12 and older. "If you continue to have sleeping problems beyond two weeks, you should see a doctor," says Marina Chang, R.Ph., pharmacist and team leader in FDA's Division of Nonprescription Regulation Development. OTC sleep aids a ...
bsapp.com - Bibb County Schools
... When taken in sufficient doses and frequency, some drugs are capable of producing withdrawal symptoms; physiological changes that encourage their continued use. When the use of these drugs ceases abruptly, a severe physical illness follows. Addicts learn regular drug use prevents this withdrawal sic ...
... When taken in sufficient doses and frequency, some drugs are capable of producing withdrawal symptoms; physiological changes that encourage their continued use. When the use of these drugs ceases abruptly, a severe physical illness follows. Addicts learn regular drug use prevents this withdrawal sic ...
Pharmaceutical Medicinal Chemistry-3
... a. Express the knowledge pertinent to SAR of drugs to suggest a suitable drug for patients. b. Demonstrate and suggest the lead molecule to pharmaceutical chemists to develop new drugs with improved efficacy. c. Access resources to gain information related to drugs SAR, pharmacodynamics and pharmaco ...
... a. Express the knowledge pertinent to SAR of drugs to suggest a suitable drug for patients. b. Demonstrate and suggest the lead molecule to pharmaceutical chemists to develop new drugs with improved efficacy. c. Access resources to gain information related to drugs SAR, pharmacodynamics and pharmaco ...
Pharmacology Review
... • If the dosing interval is shorter than 4 halflives accumulation will occur ...
... • If the dosing interval is shorter than 4 halflives accumulation will occur ...
Adenosine - Wellington ICU
... Class - short acting anti-arrhythmic - naturally occurring purine nucleoside ...
... Class - short acting anti-arrhythmic - naturally occurring purine nucleoside ...
Slide 1
... A receptor which is capable of producing its biological response in the absence of a bound ligand is said to display "constitutive activity".The constitutive activity of receptors may be blocked by invers agonist binding. Mutations in receptors that result in increased constitutive activity underl ...
... A receptor which is capable of producing its biological response in the absence of a bound ligand is said to display "constitutive activity".The constitutive activity of receptors may be blocked by invers agonist binding. Mutations in receptors that result in increased constitutive activity underl ...
File amines chap 8 drug ppt. (1).
... referred to as Neuroleptics and are most commonly prescribed as anti-psychotics. This type of tranquilizer is not widely abused. • Minor Tranquiliers are the more common of the tranquilizers. These include the Benzodiazepines, known by trade names such as Valium, Xanax, Serax, Ativan, Klonopin, Libr ...
... referred to as Neuroleptics and are most commonly prescribed as anti-psychotics. This type of tranquilizer is not widely abused. • Minor Tranquiliers are the more common of the tranquilizers. These include the Benzodiazepines, known by trade names such as Valium, Xanax, Serax, Ativan, Klonopin, Libr ...
+ Alcohol Dependence and Abuse
... concentration Irritability & combativeness Accidental suffocation due to excessive relaxation of diaphragm muscles ...
... concentration Irritability & combativeness Accidental suffocation due to excessive relaxation of diaphragm muscles ...
Neuro-fatigue
... fatigue caused by the alterations of chemicals in different parts of the brain, or chemical imbalances within the brain caused by the injury. Individuals with a brain injury describe neuro-fatigue as complete and utter exhaustion, an absolute shut down of thinking and feeling, an inability to move o ...
... fatigue caused by the alterations of chemicals in different parts of the brain, or chemical imbalances within the brain caused by the injury. Individuals with a brain injury describe neuro-fatigue as complete and utter exhaustion, an absolute shut down of thinking and feeling, an inability to move o ...
Parkinson`s Disease
... Concomitant administration of levodopa and monoamine oxidase (MAO) inhibitors, such as phenelzine, can produce a hypertensive crisis caused by enhanced catecholamine production. In patients with glaucoma, the drug can cause an increase in intraocular pressure. Antipsychotic drugs are generally ...
... Concomitant administration of levodopa and monoamine oxidase (MAO) inhibitors, such as phenelzine, can produce a hypertensive crisis caused by enhanced catecholamine production. In patients with glaucoma, the drug can cause an increase in intraocular pressure. Antipsychotic drugs are generally ...
01_CLIN_PHARMACOKYNETIC_PHARMACODYNAMIC
... Drug tolerance occurs when the body becomes accustomed to a particular drug over time so that larger doses must be given to produce the same effects. Tolerance may be acquired to the pharmacologic action of many drugs, especially opioid analgesics, alcohol, and other CNS depressants. Tolerance to ph ...
... Drug tolerance occurs when the body becomes accustomed to a particular drug over time so that larger doses must be given to produce the same effects. Tolerance may be acquired to the pharmacologic action of many drugs, especially opioid analgesics, alcohol, and other CNS depressants. Tolerance to ph ...
abstract-orderBYpresenter-board-number_DAY1
... LONG LASTING EFFECTS OF SUBCHRONIC ADMINISTRATION OF MEPHEDRONE WITH MDMA IN MICE BUSPIRONE MAINTENANCE REDUCES SEXUAL RISK-TAKING BUT DOES NOT ALTER THE ABUSE-RELATED EFFECTS OF COCAINE IN COCAINE USERS ANTIPSYCHOTIC-LIKE EFFECTS OF THE DOPAMINE D2 RECEPTOR PARTIAL AGONIST 2BROMOTERGURIDE IN RATS E ...
... LONG LASTING EFFECTS OF SUBCHRONIC ADMINISTRATION OF MEPHEDRONE WITH MDMA IN MICE BUSPIRONE MAINTENANCE REDUCES SEXUAL RISK-TAKING BUT DOES NOT ALTER THE ABUSE-RELATED EFFECTS OF COCAINE IN COCAINE USERS ANTIPSYCHOTIC-LIKE EFFECTS OF THE DOPAMINE D2 RECEPTOR PARTIAL AGONIST 2BROMOTERGURIDE IN RATS E ...
receptor
... Rarely an important characteristic of the drug Can be important if lack of potency forces inconveniently large doses Implies nothing about maximal efficacy – refers to dosage needed to produce effects ...
... Rarely an important characteristic of the drug Can be important if lack of potency forces inconveniently large doses Implies nothing about maximal efficacy – refers to dosage needed to produce effects ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.