PowerPoint Sunusu
... Primary targets of these ligand-receptor complexes are transcription factors. DNA RNA proteins Steroid hormones exert their effects by this receptor mechanism. Time course of activation and duration of the response is much longer than the other type of receptors. ...
... Primary targets of these ligand-receptor complexes are transcription factors. DNA RNA proteins Steroid hormones exert their effects by this receptor mechanism. Time course of activation and duration of the response is much longer than the other type of receptors. ...
Stimulants
... Mephedrone Severe adverse effects appear dose related but are rare at typical levels of use Interactions with other substances may be significant in risk profile student survey of mephedrone users, more than half reported adverse effects first fatality Sweden 2008 Most fatalities associated wi ...
... Mephedrone Severe adverse effects appear dose related but are rare at typical levels of use Interactions with other substances may be significant in risk profile student survey of mephedrone users, more than half reported adverse effects first fatality Sweden 2008 Most fatalities associated wi ...
Assessing Abnormal Behaviors Chris Heimerl, MA
... What is the rationale for selected medication/treatment intervention? What are the expected benefits? What are the potential consequences -with and without use of this treatment? When should the effect of the medication/treatment intervention ...
... What is the rationale for selected medication/treatment intervention? What are the expected benefits? What are the potential consequences -with and without use of this treatment? When should the effect of the medication/treatment intervention ...
Antiprotozoal and Antihilmintic Drugs
... Protozoal diseases are less easily treated than bacterial infections: Unicellular protozoal cells have metabolic processes closer to human cells than bacteria. Many of antiprotozoal drugs cause serious toxic effects and most of them are not safe I n pregnancy. ...
... Protozoal diseases are less easily treated than bacterial infections: Unicellular protozoal cells have metabolic processes closer to human cells than bacteria. Many of antiprotozoal drugs cause serious toxic effects and most of them are not safe I n pregnancy. ...
2-GENERAL PRINCIPLES FINAL
... regulatorymolecules, to stimulate or inhibit physiologic processes. ...
... regulatorymolecules, to stimulate or inhibit physiologic processes. ...
Case: Young man, dance party, collapsed outside.
... Calcium antagonists - treatment Calcium: most effective • High doses may be needed ...
... Calcium antagonists - treatment Calcium: most effective • High doses may be needed ...
Homeopathic drugs
... of symptoms; however, in a patient whose disease symptoms resemble just this mosaic of symptoms, the same drug (simile principle) would effect a cure when given in a very low dosage (“potentiation”). ...
... of symptoms; however, in a patient whose disease symptoms resemble just this mosaic of symptoms, the same drug (simile principle) would effect a cure when given in a very low dosage (“potentiation”). ...
Tolerance and Idiosyncrasy
... Receptor-mediated responses to drugs and hormonal agonists often desensitize with time, when they are given continuously or repeatedly After reaching an initial high level, the response (eg, cellular cAMP accumulation, Na+ influx, contractility, etc) gradually diminishes over seconds or minutes, ...
... Receptor-mediated responses to drugs and hormonal agonists often desensitize with time, when they are given continuously or repeatedly After reaching an initial high level, the response (eg, cellular cAMP accumulation, Na+ influx, contractility, etc) gradually diminishes over seconds or minutes, ...
（3）
... Relaxing the spasticity of skeletal muscle, probably by increasing presynaptic inhibition in the spinal cord. Used for the treatment of skeletal muscle spasms caused by central or peripheral diseases. ...
... Relaxing the spasticity of skeletal muscle, probably by increasing presynaptic inhibition in the spinal cord. Used for the treatment of skeletal muscle spasms caused by central or peripheral diseases. ...
Uppers Downers & All Arounders
... – With abstinence, disturbed mental states such as amphetamine psychosis or depression can stop for some people – Amphetamines release neurotransmitter that mimics sexual gratification ...
... – With abstinence, disturbed mental states such as amphetamine psychosis or depression can stop for some people – Amphetamines release neurotransmitter that mimics sexual gratification ...
analgesia in rats and mice
... Ibuprofen has been recommended for use as a pain reliever with a wide ranging dose of 7.5 to 30 mg/kg. Ibuprofen has anti-inflammatory, analgesic and an anti-pyretic (fever) activity. Ibuprofen is a non-specific COX inhibitor resulting in decreased prostaglandin formation. It is well absorbed orally ...
... Ibuprofen has been recommended for use as a pain reliever with a wide ranging dose of 7.5 to 30 mg/kg. Ibuprofen has anti-inflammatory, analgesic and an anti-pyretic (fever) activity. Ibuprofen is a non-specific COX inhibitor resulting in decreased prostaglandin formation. It is well absorbed orally ...
Mood Disorders
... – Have Pt develop a daily schedule – Allow sufficient time to think & act. – Clearly communicate expectations Attendance @ mealtimes, group meetings, etc. ...
... – Have Pt develop a daily schedule – Allow sufficient time to think & act. – Clearly communicate expectations Attendance @ mealtimes, group meetings, etc. ...
ANTIDEPRESSANTS: MAOIs (p.1) 1. Mono
... developed in the 1950s are very effective (as effective as the tri-cyclic antidepressants/TCAs) their use is limited by serious (even fatal) side-effects if taken with other catecholamine agonists major concern is HBP --- cardiovascular accidents (“strokes”) ...
... developed in the 1950s are very effective (as effective as the tri-cyclic antidepressants/TCAs) their use is limited by serious (even fatal) side-effects if taken with other catecholamine agonists major concern is HBP --- cardiovascular accidents (“strokes”) ...
Cocaine, Stimulants, and MDMA
... NE release correlates with subjective and physiological stimulant effects ...
... NE release correlates with subjective and physiological stimulant effects ...
Smoking Cessation Treatment Options
... nicotine-replacement therapy is more effective than using nicotine-replacement alone. This dual-medicine approach— utilizing nicotine replacement to block withdrawal symptoms in combination with Zyban® to reduce craving and stabilize mood—is an effective treatment strategy. Zyban® (bupropion) Zyban® ...
... nicotine-replacement therapy is more effective than using nicotine-replacement alone. This dual-medicine approach— utilizing nicotine replacement to block withdrawal symptoms in combination with Zyban® to reduce craving and stabilize mood—is an effective treatment strategy. Zyban® (bupropion) Zyban® ...
The Mechanistic Classification of Addictive Drugs
... selective SERT inhibition in humans (e.g., fluoxetine to treat depression) does not carry any addiction liability. Amphetamine, methamphetamine, and their many derivates. These exert their effects by reversing the action of biogenic amine transporters at the plasma membrane [41]. Amphetamines are sub ...
... selective SERT inhibition in humans (e.g., fluoxetine to treat depression) does not carry any addiction liability. Amphetamine, methamphetamine, and their many derivates. These exert their effects by reversing the action of biogenic amine transporters at the plasma membrane [41]. Amphetamines are sub ...
PHARMACOLOGY AND PHARMACEUTICAL INDUSTRY
... 5-HT2 and 5-HT3 receptors), dopamine, cholinergic (muscarinic) and NMDA receptors has been elucidated by utilizing a variety of experimental paradigms in rat and mouse, including experimental model of AlzheimerÕs disease. Blood Brain Barrier: The regulatory role of histamine (H2 receptors) and prost ...
... 5-HT2 and 5-HT3 receptors), dopamine, cholinergic (muscarinic) and NMDA receptors has been elucidated by utilizing a variety of experimental paradigms in rat and mouse, including experimental model of AlzheimerÕs disease. Blood Brain Barrier: The regulatory role of histamine (H2 receptors) and prost ...
Internal Medicine Morning Report
... • Polypharmacy means "many drugs“ • The use of more medication than is clinically indicated or warranted • 5 or more drugs ...
... • Polypharmacy means "many drugs“ • The use of more medication than is clinically indicated or warranted • 5 or more drugs ...
The Nervous System
... (1) Influence of axon diameter: the larger the axon’s diameter, the faster it conducts impulses (2) Influence of a myelin sheath: if present, the myelin sheath dramatically increases the speed of transmission because myelin acts as an insulator to prevent leakage of charge from the axon; the electri ...
... (1) Influence of axon diameter: the larger the axon’s diameter, the faster it conducts impulses (2) Influence of a myelin sheath: if present, the myelin sheath dramatically increases the speed of transmission because myelin acts as an insulator to prevent leakage of charge from the axon; the electri ...
PRESS RELEASE The Netherlands Cancer Institute (NKI) and to
... Clinical Chemistry of The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital (NKI-AVL) will collaborate on the development of a potential new therapy for Brain Tumors. Brain Tumors are highly aggressive and most often fatal cancers that affect up to 200,000 patients annually in the Unite ...
... Clinical Chemistry of The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital (NKI-AVL) will collaborate on the development of a potential new therapy for Brain Tumors. Brain Tumors are highly aggressive and most often fatal cancers that affect up to 200,000 patients annually in the Unite ...
Slide 1
... B6 vitamin, chicken, fish, pork, liver, kidney increase conversion of levodopa (左旋多巴) to dopamine (多巴胺) thus reduce the efficacy for Parkinson treatment ...
... B6 vitamin, chicken, fish, pork, liver, kidney increase conversion of levodopa (左旋多巴) to dopamine (多巴胺) thus reduce the efficacy for Parkinson treatment ...
Recreational Drugs
... Can be taken orally, intranasally, intravenously, or inhaled by smoking. Medically used for treatment of attention deficit hyperactive disorder, narcolepsy, and obesity. Produces an intense extremely pleasurable sensation. Can be followed by intense feelings of displeasure when it wears off. ...
... Can be taken orally, intranasally, intravenously, or inhaled by smoking. Medically used for treatment of attention deficit hyperactive disorder, narcolepsy, and obesity. Produces an intense extremely pleasurable sensation. Can be followed by intense feelings of displeasure when it wears off. ...
QA34_6_PregnancyPrescribing
... In general, the use of medications in pregnancy should be avoided where possible, particularly in the first trimester. The use of all medications in pregnancy should follow a careful risk versus benefit assessment. A medication with the best safety record over time should be chosen over a new medica ...
... In general, the use of medications in pregnancy should be avoided where possible, particularly in the first trimester. The use of all medications in pregnancy should follow a careful risk versus benefit assessment. A medication with the best safety record over time should be chosen over a new medica ...
WHY ARE WE STILL STUCK AROUND BENZODIAZEPINES? Introduction SMMGP Manchester, October 2013
... and BZ receptors, which become less responsive, so that inhibitory actions are decreased • Rate of development of tolerance may be rapid, but varies for different drug effects; relief of anxiety, sedation and pleasure (depending on no. / complexity of receptors) • Can also develop at different speed ...
... and BZ receptors, which become less responsive, so that inhibitory actions are decreased • Rate of development of tolerance may be rapid, but varies for different drug effects; relief of anxiety, sedation and pleasure (depending on no. / complexity of receptors) • Can also develop at different speed ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.