Download Smoking Cessation Treatment Options

Smoking Cessation Treatment Options
that is superior to nicotine replacement in
helping smokers stop smoking and in
reducing relapse. Zyban® also appears to
prevent weight gain and depression
associated with smoking cessation. The
length of treatment will vary depending on a
person’s mood, withdrawal symptoms and
the intensity of the craving.
The U.S. Food and Drug Administration
has approved five medications to help
people quit smoking:
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
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bupropion SR (brand name
Zyban®)—available by prescription
nicotine gum—available over-thecounter
nicotine inhaler—available by
prescription
nicotine nasal spray—available by
prescription
nicotine patch—available by
prescription and over-the-counter
Using Zyban® in combination with
nicotine-replacement therapy is more
effective than using nicotine-replacement
alone. This dual-medicine approach—
utilizing nicotine replacement to block
withdrawal symptoms in combination with
Zyban® to reduce craving and stabilize
mood—is an effective treatment strategy.
Zyban® (bupropion)
Zyban® is the first non-nicotine treatment
All drugs of abuse, including nicotine, cause
a dopamine surge and subsequent depletion
in the brain’s reward pathway. Zyban® is
thought to lessen nicotine craving by
blocking dopamine from being recycled too
quickly (inhibiting re-uptake), thereby
increasing the availability of dopamine
along the brain’s reward path.
Nicotine-replacement therapy
There are several types of over-the-counter
nicotine-replacement products, including
patches, gum, nasal spray and inhaler. They
are all about equally effective; about 28
percent of smokers who use them
successfully quit. The key is to find the right
approach for you. Some smokers like to play
with the inhaler like they would a cigarette.
For others, feeling the spray in the back of
their throat is rewarding.
You may want to consult a health care
professional such as your primary care
physician who can help you develop a
treatment plan.
©1999-2005 University of Florida McKnight Brain
Institute
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